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1.
PIERLUIGI TABACCHI MARIELLA CHIRICOLO MARINELLA CENCI FRANCESCO BARBONI MARCO MANFRINI GAETANO BACCI PIERO PICCI MARIO CAMPANACCI FEDERICO LICASTRO CLAUDIO FRANCECHI 《Tissue antigens》1982,20(4):251-253
A homogeneous group of 53 Caucasian subjects with high-grade osteosarcoma (OS) was typed for HLA-A and B locus antigens. Although no significant differences in the distribution of these antigens were found in comparison with 425 local controls, a trend towards an increase of HLA-B18 and decrease of HLA-B21 was observed. All the patients underwent amputation plus adjuvant chemotherapy and among the 29 patients with a follow-up longer than one year, 9 out of 10 subjects with HLA-A3 antigens developed metastases within a few months. None of the OS patients had the HLA-A3, B7 haplotype which is present in linkage-disequilibrium in the control population. 相似文献
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EDUARDO ARANA‐RUEDA M.D. Ph.D. ALONSO PEDROTE M.D. Ph.D. LORENA GARCÍA‐RIESCO M.D. ALVARO ARCE‐LEÓN M.D. FEDERICO GÓMEZ‐PULIDO M.D. JUAN‐MANUEL DURÁN‐GUERRERO M.D. AGUSTÍN FERNÁNDEZ‐CISNAL M.D. MANUEL FRUTOS‐LÓPEZ M.D. JUAN‐ANTONIO SÁNCHEZ‐BROTONS M.D. 《Pacing and clinical electrophysiology : PACE》2015,38(2):216-224
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MARCO SCAGLIONE M.D. DOMENICO CAPONI M.D. MATTEO ANSELMINO M.D. Ph.D. FRANCESCA DI CLEMENTE M.D. ALESSANDRO BLANDINO M.D. FEDERICO FERRARIS M.D. PAOLO DI DONNA M.D. ELISA EBRILLE M.D. FRANCK HALIMI M.D. JEAN F. LECLERCQ M.D. COSTANZA IUNCO M.D. CARLOEUGENIO VAUDAGNA M.D. FEDERICO CESARANI M.D. FIORENZO GAITA M.D. 《Journal of cardiovascular electrophysiology》2014,25(12):1299-1305
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ANTONIO MICHELUCCI LUIGI PADELETTI REA CHELUCCI ALESSANDRO MEZZANI MARIA C. PORCIANI FEDERICO CARUSO EMANUELE LEBRUN FRANCESCA BACCI MOIRA MARTELLI GIAN FRANCO GENSINI 《Pacing and clinical electrophysiology : PACE》1996,19(5):758-767
Signal-averaged P wave of 42 patients with lone paroxysmal atrial fibrillation (PAF) and 29 normal subjects (N) were recorded, using three orthogonal leads and analyzed in the time and frequency (entire P wave or a 100-ms segment ranging from 75 ms before to 25 ms after the end of P wave) domains. PAFs were divided into a group of 12 having ≥ 2 attacks a month (HF) and a group of 30 having ≤ 2 attacks a year (LF). Statistically significant differences were absent with regard to ages of PAF and N; ages of HF, LF, and N at the time of signal-averaged ECG; ages of HF and LF at the time of the first arrhythmic episode; and elapsed times from the first episode. Length of P wave and some frequency-domain parameters were found to be significantly correlated with age. PAF showed a significantly longer duration of P wave in the frontal plane using the time-domain analysis. Frequency analysis was found to be useful in evaluating the influence of attack frequency. HF showed significantly higher values of some frequency-domain parameters than LF and N, while the three groups did not differ for time-domain analysis. P wave duration and frequency content of the three orthogonal leads proved to be significantly different in PAF and N. Right and left atrial echocardiographic dimensions proved to be higher (even if within normal limits) in HF than in LF and N. Results suggest that frequency analysis should be performed on the entire P wave. 相似文献
5.
A. J. MORRIS M. PANCHATCHARAM H. Y. CHENG L. FEDERICO Z. FULKERSON S. SELIM S. MIRIYALA D. ESCALANTE-ALCALDE† S. S. SMYTH‡ 《Journal of thrombosis and haemostasis》2009,7(S1):38-43
Summary. Lysophosphatidic acid (LPA), its sphingolipid homolog sphingosine 1-phosphate (S1P) and several other related molecules constitute a family of bioactive lipid phosphoric acids that function as receptor-active mediators with roles in cell growth, differentiation, inflammation, immunomodulation, apoptosis and development. LPA and S1P are present in physiologically relevant concentrations in the circulation. In isolated cell culture systems or animal models, these lipids exert a range of effects that suggest that S1P and LPA could play important roles in maintaining normal vascular homeostasis and in vascular injury responses. LPA and S1P act on a series of G protein-coupled receptors, and LPA may also be an endogenous regulator of PPARγ activity. In this review, we discuss potential roles for lysolipid signaling in the vasculature and mechanisms by which these bioactive lipids could contribute to cardiovascular disease. 相似文献
6.
MARGO M.; ALTOMONTE L.; ZOLI A.; MIRONE L.; MASSI G.; FEDERICO F. 《Rheumatology (Oxford, England)》1990,29(2):145-146
The authors report a case of eosinophilic fasciitis with anhistopathological pattern of inflammatory neutrophilic vasculitisassociated with the typical inflammatory infiltrate. The presenceof this type of vasculitis which may be observed in the initialforms of scleroderma supports the hypothesis of a considerableoverlap between these two entities. KEY WORDS: Vasculitis, Scleroderma, Eosinophilia, Skin 相似文献
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EMANUELE MELIGA M.D. Ph.D. MAURO DE BENEDICTIS M.D. ANDREA GAGNOR M.D. FEDERICO CONROTTO M.D. MARCO NOVARA M.D. INNOCENZO SCROCCA M.D. FERDINANDO VARBELLA M.D. SEBASTIANO MARRA M.D. MARIA ROSA CONTE M.D. 《Journal of interventional cardiology》2013,26(4):351-358