全文获取类型
收费全文 | 1849篇 |
免费 | 115篇 |
国内免费 | 44篇 |
专业分类
耳鼻咽喉 | 22篇 |
儿科学 | 87篇 |
妇产科学 | 10篇 |
基础医学 | 263篇 |
口腔科学 | 40篇 |
临床医学 | 169篇 |
内科学 | 280篇 |
皮肤病学 | 30篇 |
神经病学 | 62篇 |
特种医学 | 156篇 |
外科学 | 152篇 |
综合类 | 237篇 |
预防医学 | 132篇 |
眼科学 | 17篇 |
药学 | 185篇 |
中国医学 | 78篇 |
肿瘤学 | 88篇 |
出版年
2023年 | 9篇 |
2022年 | 12篇 |
2021年 | 38篇 |
2020年 | 20篇 |
2019年 | 14篇 |
2018年 | 17篇 |
2017年 | 36篇 |
2016年 | 27篇 |
2015年 | 45篇 |
2014年 | 65篇 |
2013年 | 87篇 |
2012年 | 95篇 |
2011年 | 112篇 |
2010年 | 88篇 |
2009年 | 82篇 |
2008年 | 113篇 |
2007年 | 90篇 |
2006年 | 79篇 |
2005年 | 63篇 |
2004年 | 46篇 |
2003年 | 51篇 |
2002年 | 41篇 |
2001年 | 45篇 |
2000年 | 38篇 |
1999年 | 40篇 |
1998年 | 30篇 |
1997年 | 34篇 |
1996年 | 30篇 |
1995年 | 24篇 |
1994年 | 13篇 |
1993年 | 18篇 |
1992年 | 19篇 |
1991年 | 25篇 |
1990年 | 24篇 |
1989年 | 32篇 |
1988年 | 29篇 |
1987年 | 24篇 |
1986年 | 15篇 |
1985年 | 30篇 |
1984年 | 16篇 |
1983年 | 14篇 |
1982年 | 11篇 |
1981年 | 20篇 |
1980年 | 16篇 |
1978年 | 13篇 |
1977年 | 13篇 |
1976年 | 14篇 |
1975年 | 15篇 |
1974年 | 10篇 |
1972年 | 11篇 |
排序方式: 共有2008条查询结果,搜索用时 15 毫秒
1.
HA Carpay P Matthijsse M Steinbuch PGH Mulde 《Cephalalgia : an international journal of headache》1997,17(5):591-595
In an open, randomized cross-over study in 124 patients, we compared the efficacy, safety and patient preference of oral and subcutaneous sum triptan in the acute treatment of migraine. Patients were treated for 3 attacks or 3 months and then crossed over. Primary clinical efficacy was defined as a reduction in headache severity on a four-point self-rating scale from severe (3) or moderate (2) to mild (1) or none (0), or mild (1) to none (0). Efficacy was evaluated 2 h after the administration of subcutaneous and 4h after the administration of oral sumatriptan. Subcutaneous sumatriptan was significantly more effective than oral sumatriptan in relieving headache (over all three attacks 78% vs 61% improvement), improving clinical disability (55% vs 41 % improvement) and relieving nausea (69% vs 53%), vomiting (72% vs 32%) and phono- or photophobia (67% vs 49%). Median time to recurrence was shorter after subcutaneous (12.5 h) than after oral sumatriptan (18 h); the number of patients experiencing a recurrence was similar Patients reported more adverse events after subcutaneous sumatriptan (1.32 per attack) than after the oral form (0.85 per attack), but all adverse events were mild to moderate in intensity and of short duration. Patient opinion was more often positive after subcutaneous sumatriptan. These results may be useful in counselling patients to choose between the available marketed formulations of sumatriptan. 相似文献
2.
One hundred and one patients, nursed in an intensive care unit for at least 24h, were monitored for bacterial colonization
and infection. The infection rates were similar to those in other reports. Patients were not generally colonized with common
environmental strains in the unit. Bacterial dissemination between patients was uncommon. No gentamicin resistant gram negative
or Staphylococcus aureus strains were observed, nor methicillin resistant Staphylococcus aureus strains. the hypothesis that these favourable conditions are partly related to the excellent isolation and barrier nursing
facilities in the unit cannot be fully substantiated. 相似文献
3.
4.
超细β-磷酸三钙/聚-L-乳酸复合材料的制备与骨折内固定器的加工 总被引:3,自引:0,他引:3
目的:制备分散性良好的超细β-磷酸三钙(β-TCP)/聚-L-乳酸(PLLA)复合材料及新型可吸收骨折内固定器。方法:通过研磨方法制备β-TCP超细粒子,用一缩二乙二醇作分散剂研磨β-TCP后,再将β-TCP与PLLA超声混合,制得复合材料,经注塑加工制成可吸收骨钉,并采用扫描电镜等方法进行表征。结果与结论:用一缩二乙二醇作分散剂研磨β-TCP后再经超声混合,可以使β-TCP超细粒子在复合材料中分散均匀,粒子大小仅为300nm左右,β-TCP与PLlA基体之间结合良好。超细β-TCP/PLLA复合材料可加工成可吸收骨钉,弯曲强度达到100MPa左右,完全满足松质骨内固定的要求。 相似文献
5.
6.
H H Euler J O Schroeder 《The New England journal of medicine》1992,327(14):1028; author reply 1029-1028; author reply 1030
7.
H H Euler J O Schroeder R A Zeuner E Teske 《The International journal of artificial organs》1991,14(10):639-646
A group of clinics cooperating as the Lupus Plasmapheresis Study Group (LPSG) is starting an international multicenter study of the treatment of severe systemic lupus erythematosus. The primary goal of this randomized and prospective trial is to establish whether treatment with plasmapheresis and subsequent pulse cyclophosphamide improves the outcome compared to treatment with pulse cyclophosphamide alone. The underlying rationale assumes that plasmapheresis: a) eliminates pathogenic autoantibodies and immune complexes and b) induces a compensatory activation of pathogenic lymphocyte clones through a feed-back between circulating antibodies and their respective antibody-producing clones. Synchronization of plasmapheresis with subsequent pulse cyclophosphamide should enhance the deletion of pathogenic clones during the period of greatest vulnerability. This overview reviews the first results of treatment approaches based on this concept and summarizes the design of the LPSG trial. 相似文献
8.
The classification of fractures of the scapula (type A: body and process fractures; type B: neck fractures; type C: glenoid fractures) is shown, and the indications for conservative and operative treatment are described, as are the surgical approaches and operative techniques. In our hospital, 93 patients with 153 fractures of the scapula type A, B or C (ratio 1.6:1) were treated. This ratio was 1.7:1 in patients treated by operation. The indication for operation was usually glenoid fractures with accessory process fractures. 相似文献
9.
MN Tabrizi† C Chams-Davatchi† N Esmaeeli† P Noormohammadpoor† F Safar† H Etemadzadeh† HA Ettehadi‡ F Gorouhi† 《Journal of the European Academy of Dermatology and Venereology》2007,21(1):79-84
BACKGROUND: Pemphigus vulgaris (PV) is a severe blistering disease involving the skin and mucous membranes. The most common causes of death in these patients are adverse effects of drugs, and infection. Skin lesions are one of the important sources of infection. Thus, any local treatment that could reduce healing time of lesions and consequently reduce the total dosage of drugs needed to treat is favourable. OBJECTIVE: To evaluate the efficacy of epidermal growth factor (EGF) in reducing healing time of lesions in patients with pemphigus vulgaris. METHODS: In this randomized, double-blind, within-patient, left/right, controlled trial, 20 hospitalized patients with pathologial and immunohistologial (direct and indirect immunoflourecence) proven pemphigus vulgaris (PV) were chosen. In addition, all patients had at least one appropriate pemphigus lesion on each side of the body that had not healed after 2-week systemic therapy and sterile saline washing. EGF (10 microg/g) in 0.1% silver sulfadiazine cream vs. 0.1% silver sulfadiazine cream alone was applied randomly on one side of the body. RESULTS: Kaplan-Meier survival analysis suggested that median time to heal with application of EGF plus silver sulfadiazine cream was 9 days, in comparison with 15 days for silver sulfadiazine cream alone (log-rank test, P=0.0003). No intervention-related adverse effect was observed during the study. CONCLUSIONS: EGF can significantly reduce healing time of skin lesions in patients with pemphigus vulgaris, at least when this cream base is applied (Cochrane skin group identifier: CSG20). 相似文献
10.