全文获取类型
收费全文 | 691篇 |
免费 | 49篇 |
国内免费 | 2篇 |
专业分类
耳鼻咽喉 | 1篇 |
儿科学 | 32篇 |
妇产科学 | 8篇 |
基础医学 | 107篇 |
口腔科学 | 9篇 |
临床医学 | 94篇 |
内科学 | 141篇 |
皮肤病学 | 14篇 |
神经病学 | 79篇 |
特种医学 | 15篇 |
外科学 | 79篇 |
综合类 | 4篇 |
一般理论 | 2篇 |
预防医学 | 57篇 |
眼科学 | 26篇 |
药学 | 43篇 |
肿瘤学 | 31篇 |
出版年
2023年 | 11篇 |
2022年 | 18篇 |
2021年 | 32篇 |
2020年 | 13篇 |
2019年 | 26篇 |
2018年 | 26篇 |
2017年 | 20篇 |
2016年 | 23篇 |
2015年 | 19篇 |
2014年 | 34篇 |
2013年 | 36篇 |
2012年 | 49篇 |
2011年 | 53篇 |
2010年 | 33篇 |
2009年 | 28篇 |
2008年 | 33篇 |
2007年 | 31篇 |
2006年 | 33篇 |
2005年 | 32篇 |
2004年 | 34篇 |
2003年 | 17篇 |
2002年 | 25篇 |
2001年 | 3篇 |
2000年 | 2篇 |
1999年 | 2篇 |
1998年 | 2篇 |
1997年 | 6篇 |
1995年 | 2篇 |
1994年 | 5篇 |
1992年 | 4篇 |
1991年 | 6篇 |
1990年 | 8篇 |
1989年 | 7篇 |
1988年 | 8篇 |
1987年 | 6篇 |
1986年 | 7篇 |
1985年 | 3篇 |
1984年 | 4篇 |
1979年 | 4篇 |
1978年 | 2篇 |
1977年 | 4篇 |
1975年 | 2篇 |
1974年 | 3篇 |
1973年 | 2篇 |
1971年 | 4篇 |
1970年 | 3篇 |
1967年 | 4篇 |
1965年 | 2篇 |
1943年 | 1篇 |
1931年 | 1篇 |
排序方式: 共有742条查询结果,搜索用时 31 毫秒
1.
2.
Peter Feindt Jens Litmathe Adina B?rgens Udo Boeken Muhammed Kurt Emmeran Gams 《European journal of cardio-thoracic surgery》2007,31(4):614-617
OBJECTIVE: Enlargement of the ascending aorta is often combined with valvular, coronary, or other cardiac diseases. Reduction aortoplasty can be an optional therapy; however, indications regarding the diameter of aorta, the history of dilatation (poststenosis, bicuspid aortic valve), or the intraoperative management (wall excision, reduction suture, external reinforcement) are not established. METHODS: In a retrospective study between 1997 and 2005, we investigated 531 patients operated for aneurysm or ectasia of the ascending aorta (diameter: 45-76mm). Of these, in 50 patients, size-reducing ascending aortoplasty was performed. External reinforcement with a non-coated dacron prosthesis was added in order to stabilize the aortic wall. RESULTS: Aortoplasty was associated with aortic valve replacement in 47 cases (35 mechanical vs 12 biological), subvalvular myectomy in 29 cases, and CABG in 13 cases. The procedure was performed with low hospital mortality (2%) and a low postoperative morbidity. Computertomographic and echocardiographic diameters were significantly smaller after reduction (55.8+/-9mm down to 40.51+/-6.2mm (CT), p<0.002; 54.1+/-6.7mm preoperatively down to 38.7+/-7.1mm (echocardiography), p<0.002), with stable performance in long-term follow-up (mean follow-up time: 70 months). CONCLUSIONS: As demonstrated in this study, size reduction of the ascending aorta using aortoplasty with external reinforcement is a safe procedure with excellent long-term results. It is a therapeutic option in modern aortic surgery in patients with poststenotic dilatation of the aorta without impairment of the sinotubular junction of the aortic valve and root. 相似文献
3.
Morbidity and death during liver resection in children are due to hemorrhage and the consequences of massive transfusion. To overcome these problems, a new rapid method of blood transfusion was used in four children (8 to 35 months, 8.6 to 13 kg) undergoing extensive hepatic resection for tumor (tumor weight, 440 to 1625 gm). The rapid infusion device consisted of a roller pump and a bubble oxygenator-warmer circuit primed with washed packed red cells resuspended in fresh-frozen plasma and calcium-free balanced salt solution (Plasmalyte). The infusate was warmed, oxygenated, and buffered before it was administered. An average of 5130 ml per patient of this reconstituted blood was infused at an average rate of 122 +/- 45 ml/min, with peak infusion rates sometimes as great as 1 L/min. Cardiac output, pulmonary artery wedge pressure, body temperature, urine output, blood gases, blood chemistries, and coagulation factors remained unchanged during and after these massive transfusions. Blood transfusion at rapid rates required during pediatric liver resection can be accomplished safely if the storage lesion of the bank blood is previously corrected. 相似文献
4.
5.
This paper describes the development of a digitized, real-time, microcomputer-based signal processing system which records the following variables: systolic and diastolic blood pressure, heart rate, pulse transit time, blood volume pulse, and R-, S-, and T-wave amplitudes of EKG signals. Forty-eight healthy subjects participated in a three-task stress response study in order to gather initial data for evaluating the reliability and validity of this monitoring system. The three tasks represented replications of earlier studies: 1) reading aloud of a monotonous neutral text (Reading Only, RO); 2) mental arithmetic without vocalization (Arithmetic Quiet, AQ); and 3) mental arithmetic with vocalization (Arithmetic Aloud, AA). The findings provided support for the reliability and validity of the new monitoring system given that few data were lost, and resting values as well as differential task responses were found to be comparable with earlier data sets derived via similar experimental protocols. 相似文献
6.
Primary antibody deficiency syndromes are a rare group of disorders present at any age, with complex polygenic disorders. We report the forth case of polyglandular autoimmune syndrome (PAS) type IIIc worldwide with complex clinical features and no family history of endocrine disorders or primary immunodeficiencies. Our patient, a 44-year-old Caucasian female was diagnosed with PAS type IIIc due to the presence of autoimmune thyroiditis, autoimmune alopecia diffusa and primary ovarian insufficiency, associated with lymphoproliferative disease and primary antibody failure. Treatment included lifelong intravenous immunoglobulin, supplements and antibiotics. The clinical complexity and rare occurrence made it challenging to determine diagnosis and provide better treatment for the patient. The current case provides an insight of the challenges to determine primary antibody failure signs in the presence of PAS which will further help to determine diagnosis and therapeutic treatment for PAS patients. 相似文献
7.
8.
9.
10.