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为了确定凝血因子Ⅶ:C、Ⅸ:C 和 vWF:Ag 在胎儿期的发生部位,本文就用水囊引产法获得胎龄18~23周的胎儿,分别测定其肾、肝、脾、骨髓和胸腺等5种脏器中凝血因子Ⅷ:C、Ⅸ:C 及 vWF:Ag 的水平。并比较了肾组织培养前后凝血因子水平的变化。结果表明,肾脏组织凝血因子Ⅷ:C、Ⅸ:C 的水平明显高于其他组织。随着培养后细胞数的增殖,Ⅷ:C 和Ⅸ:C 的水平也有了提高。因此,初步认定胎儿肾脏组织可能是合成或贮存凝血因子Ⅷ:C 和Ⅸ:C 的器官之一。 相似文献
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库血贮存3~4周后,红细胞的2,3-二磷酸甘油酸(2,3-DPG)含量降至2.903±0.863pM/gHb(为新鲜血的12.96%),经37℃水浴4小时后,红细胞2,3-DPG升至4.177±1.324μM/gHb(为新鲜血的18.65%),乳酸生成值为3.860±O.839mg/mgFe,P_(?)为36~38.5mmHg。库血内加12%党参黄芪注射液,37℃水浴4小时,红细胞2,3-DPG 含量升至9.111±1.999μM/gHb(为新鲜血的40.67%),乳酸生成值为5.092±0.635mg/mgFe,P_(50)为32~33mmHg。此结果似说明党参黄芪能促进红细胞糖酵解及提高2,3-DPG 含量,改善释氧能力。 相似文献
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Xu Zhen-bang徐振邦 Wu Jue吴珏 Chen Hou-chu陈厚初Lu Yi-jian陆奕健 Gong Mei-chun龚美纯 《中华医学杂志(英文版)》1987,100(8):654-657
The 2,3-diphosphoglycerate (2,3-DPG) content
of freshly drawn blood is 22.4+1.49µM/gHb. When
whole blood with ACD preservative solution. is
stored at 4 C for 3-4 weeks, the erythrocyte 2,3-DPG
content decreases t0 2.91+0.86 µM/gHb (12.96% that
of fresh blood). The erythrocyte oxygen delivery
capacity lowered correspondingly with the decrease
in 2,3-DPG content. Extract of Radix Codonopsis
pilosulae党参 and Radix Astragali黄芪 were
added t0 2,3-DPG depleted blood and stored at 37C
for 4 hours. Now the 2,3-DPG content was 9.11+
2.00 uM/gHb (40.67% that of fresh blood), lactic
acid 5.09+0.64 mg/mgFe and P50 32-33 mmHg.
Control samples without the herbals added were
correspondingly 4.18+1.32 µM/gHb (18.56% that of
fresh blood), 3.86+0.84 mg/mgFe and 36 38.5 mmHg.
It appeared that Radix Codonopsis pilosullae and
Radix Astragali can promote erythrocytc glycolysis,
increase erythrocyte 2,3-DPG content and improve
oxygen delivery capacity. 相似文献
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