全文获取类型
收费全文 | 3318篇 |
免费 | 214篇 |
国内免费 | 4篇 |
专业分类
耳鼻咽喉 | 63篇 |
儿科学 | 168篇 |
妇产科学 | 62篇 |
基础医学 | 328篇 |
口腔科学 | 131篇 |
临床医学 | 266篇 |
内科学 | 751篇 |
皮肤病学 | 45篇 |
神经病学 | 218篇 |
特种医学 | 90篇 |
外科学 | 543篇 |
综合类 | 44篇 |
一般理论 | 1篇 |
预防医学 | 183篇 |
眼科学 | 73篇 |
药学 | 324篇 |
中国医学 | 11篇 |
肿瘤学 | 235篇 |
出版年
2023年 | 26篇 |
2022年 | 46篇 |
2021年 | 95篇 |
2020年 | 70篇 |
2019年 | 78篇 |
2018年 | 116篇 |
2017年 | 114篇 |
2016年 | 87篇 |
2015年 | 88篇 |
2014年 | 134篇 |
2013年 | 173篇 |
2012年 | 248篇 |
2011年 | 271篇 |
2010年 | 161篇 |
2009年 | 138篇 |
2008年 | 215篇 |
2007年 | 226篇 |
2006年 | 184篇 |
2005年 | 175篇 |
2004年 | 155篇 |
2003年 | 131篇 |
2002年 | 113篇 |
2001年 | 41篇 |
2000年 | 39篇 |
1999年 | 39篇 |
1998年 | 28篇 |
1997年 | 12篇 |
1996年 | 23篇 |
1995年 | 16篇 |
1994年 | 17篇 |
1993年 | 13篇 |
1992年 | 28篇 |
1991年 | 30篇 |
1990年 | 32篇 |
1989年 | 19篇 |
1988年 | 16篇 |
1987年 | 12篇 |
1986年 | 16篇 |
1985年 | 15篇 |
1984年 | 9篇 |
1983年 | 17篇 |
1982年 | 7篇 |
1981年 | 10篇 |
1980年 | 8篇 |
1979年 | 10篇 |
1977年 | 4篇 |
1976年 | 5篇 |
1974年 | 4篇 |
1970年 | 4篇 |
1968年 | 4篇 |
排序方式: 共有3536条查询结果,搜索用时 15 毫秒
1.
Accurate diagnosis and recognition of predisposing factors has been shown to be challenging in lower limb cellulitis (LLC). Assessment of 1746 consecutive patients with cellulitis presenting to a UK university hospital showed increasing overdiagnosis, with only 31.9% of patients referred during the period 2015–2018 having the diagnosis of LLC confirmed. Recognition of at least one predisposing factor increased from 61% to 89% following introduction of more specific screening questions. This identified a need for better primary care dermatology education and the benefit of a proforma with specific screening questions for reversible predisposing factors for LLC. 相似文献
2.
Darren R. Feldman MD Yasser Ged MBBS Chung-Han Lee PhD Andrea Knezevic MS Ana M. Molina MD Ying-Bei Chen PhD Joshua Chaim DO Devyn T. Coskey MS Samuel Murray MS Satish K. Tickoo MD Victor E. Reuter MD Sujata Patil PhD Han Xiao MD Jahan Aghalar MD Arlyn J. Apollo MD Maria I. Carlo MD Robert J. Motzer MD Martin H. Voss MD 《Cancer》2020,126(24):5247-5255
3.
A 17-year-old man presented with signs of peritonitis. Laparotomy revealed gangrene of the stomach without obvious cause. The patient underwent total gastrectomy with esophago-jejunal anastomosis with formation of jejunal pouch. Bacterial culture of the peritoneal fluid grew Strept. pyogenes and E. coli. The patient was discharged on day 21 after a stormy postoperative course. 相似文献
4.
Ajay Punpale C S Pramesh Nirmala Jambhekar Rajesh C Mistry 《Annals of thoracic and cardiovascular surgery》2006,12(6):425-427
Liposarcomas are extremely rare in the mediastinum. They may achieve considerable size before causing any symptoms. Mediastinal liposarcomas may invade surrounding structures like the pericardium or the superior vena cava. Complete surgical excision is the optimal treatment in resectable cases. Excision of adjacent structures like the pericardium may be needed if the tumor infiltrates them. We report on a case of a giant liposarcoma of the mediastinum involving both hemithoraces and extending into the neck, which was successfully managed by complete surgical excision. 相似文献
5.
I(indigenous)-compounds are age-related, carcinogen adduct-like, putative indigenous DNA modifications detectable by 32P-postlabeling assay in untreated animals. To investigate the origins of these DNA derivatives, we examined the effects of dietary vitamin E, a natural antioxidant, on I-compounds of rat liver and kidney DNA. Weanling female Sprague-Dawley rats were fed Draper's diets containing 0, 100, 1000, or 10,000 mg/kg alpha-tocopheryl acetate for 6 mo. The DNA from four individual rats of each group was analyzed by a nuclease P1-enhanced version of the 32P-postlabeling assay for DNA adducts. The amount of vitamin E in the liver was measured by high performance liquid chromatography. Rats fed vitamin E-deficient diet (0 mg/kg) showed identical profiles and similar levels of I-compounds as those fed the 100 mg/kg diet. Most I-spots were significantly intensified and one tissue-specific extra spot was found in both liver and kidney DNA of rats fed the 1000 or 10,000 mg/kg vitamin E diet. However, one of the five major I-spots detected in the kidney was weaker in the 1000 and 10,000 mg/kg groups than in the 0 and 100 mg/kg groups. These results show that formation of most I-compounds was not affected by vitamin E-deficient diet, and that long-term feeding of diet containing high levels of vitamin E may cause metabolic alterations leading to an increased formation of DNA-reactive (potentially mutagenic or carcinogenic) electrophiles. 相似文献
6.
7.
C S Pramesh Bhulaxmi P Madur Sudip Raina Sangeeta B Desai Rajesh C Mistry 《Annals of thoracic and cardiovascular surgery》2004,10(3):187-190
Angiosarcoma is a rare, highly malignant tumor arising from endothelial cells of small blood vessels. They usually occur in the skin, deep soft tissues, breast and liver. Pleural angiosarcomas are extremely rare and are restricted to case reports in medical literature. It is very difficult to distinguish them from malignant mesotheliomas on clinical, radiological and even histopathological features. Immunohistochemistry is valuable in making the diagnosis, showing negative reactivity for mesothelial markers and positivity for vascular markers. Prognosis is generally dismal except in occasional cases where the disease is localized and amenable for surgical resection. We report a 55-year-old man who presented to us with chest pain, cough and hemoptysis and was diagnosed to have a pleural angiosarcoma. 相似文献
8.
Jean-Francois Morin M.D. Bergez F. Mistry M.D. FRCPC Lisa Knowlton M.D. 《Journal of cardiac surgery》2007,22(4):356-358
Abstract In this case report we describe a situation where despite a normal TEE exam immediately postcardiopulmonary bypass, there was no flow in the left internal mammary artery graft to the left anterior descending artery. This was picked up by coronary Doppler and subsequently repaired. 相似文献
9.
Steven N Singh X Charlene Tang Bramah N Singh Paul Dorian Domenic J Reda Crystal L Harris Ross D Fletcher Satish C Sharma J Edwin Atwood Alan K Jacobson H Daniel Lewis Becky Lopez Dennis W Raisch Michael D Ezekowitz 《Journal of the American College of Cardiology》2006,48(4):721-730
OBJECTIVES: The purpose of this study was to determine quality of life (QOL) and exercise performance (EP) in patients with persistent atrial fibrillation (AF) converted to sinus rhythm (SR) compared with those remaining in or reverting to AF. BACKGROUND: Restoration of SR in patients with AF improving QOL and EP remains controversial. METHODS: Patients with persistent AF were randomized double-blind to amiodarone, sotalol, or placebo. Those not achieving SR at day 28 were cardioverted and classified into SR or AF groups at 8 weeks (n = 624) and 1 year (n = 556). The QOL (SF-36), symptom checklist (SCL), specific activity scale (SAS), AF severity scale (AFSS), and EP were assessed. RESULTS: Favorable changes were seen in SR patients at 8 weeks in physical functioning (p < 0.001), physical role limitations (p = 0.03), general health (p = 0.002), and vitality (p < 0.001), and at 1 year in general health (p = 0.007) and social functioning (p = 0.02). Changes in the scores for SCL severity (p = 0.01), functional capacity (p = 0.003), and AFSS symptom burden (p < 0.001) at 8 weeks and in SCL severity (p < 0.01) and AF symptom burden (p < 0.001) at 1 year showed significant improvements in SR versus AF. Symptomatic patients were more likely to have improvement. The EP in SR versus AF was greater from baseline to 8 weeks (p = 0.01) and to 1 year (p = 0.02). The EP correlated with physical functioning and functional capacity except in the AF group at 1 year. CONCLUSIONS: In patients with persistent AF, restoration and maintenance of SR was associated with improvements in QOL measures and EP. There was a strong correlation between QOL measures and EP. 相似文献
10.
A. Satish Chandra Sanjeev Mohanty 《Indian journal of otolaryngology and head and neck surgery》2007,59(1):43-44
Role of Embolisation in preoperative management of Nasopharyngeal angiofibroma is well established in present day therapeutic
modalities. An improvised technique i.e., subselective embolisation has been provided by Interventional radiologists to fortify
the therapeutic results. This study compares the final outcome of seven cases, four of which were embolised pre operatively.
Each case was dealt with varying surgical approaches. 相似文献