全文获取类型
收费全文 | 3152篇 |
免费 | 118篇 |
国内免费 | 24篇 |
专业分类
耳鼻咽喉 | 146篇 |
儿科学 | 138篇 |
妇产科学 | 148篇 |
基础医学 | 229篇 |
口腔科学 | 196篇 |
临床医学 | 237篇 |
内科学 | 611篇 |
皮肤病学 | 42篇 |
神经病学 | 207篇 |
特种医学 | 144篇 |
外科学 | 619篇 |
综合类 | 51篇 |
一般理论 | 1篇 |
预防医学 | 81篇 |
眼科学 | 140篇 |
药学 | 136篇 |
中国医学 | 30篇 |
肿瘤学 | 138篇 |
出版年
2024年 | 2篇 |
2023年 | 32篇 |
2022年 | 41篇 |
2021年 | 58篇 |
2020年 | 56篇 |
2019年 | 57篇 |
2018年 | 81篇 |
2017年 | 68篇 |
2016年 | 92篇 |
2015年 | 108篇 |
2014年 | 102篇 |
2013年 | 160篇 |
2012年 | 243篇 |
2011年 | 250篇 |
2010年 | 157篇 |
2009年 | 139篇 |
2008年 | 223篇 |
2007年 | 217篇 |
2006年 | 223篇 |
2005年 | 211篇 |
2004年 | 205篇 |
2003年 | 204篇 |
2002年 | 133篇 |
2001年 | 59篇 |
2000年 | 43篇 |
1999年 | 26篇 |
1998年 | 17篇 |
1997年 | 12篇 |
1996年 | 14篇 |
1995年 | 9篇 |
1994年 | 8篇 |
1993年 | 7篇 |
1992年 | 5篇 |
1991年 | 4篇 |
1990年 | 7篇 |
1989年 | 2篇 |
1985年 | 2篇 |
1984年 | 3篇 |
1983年 | 3篇 |
1982年 | 2篇 |
1981年 | 1篇 |
1979年 | 1篇 |
1978年 | 1篇 |
1977年 | 1篇 |
1976年 | 1篇 |
1974年 | 1篇 |
1962年 | 1篇 |
1961年 | 1篇 |
1959年 | 1篇 |
排序方式: 共有3294条查询结果,搜索用时 15 毫秒
1.
2.
Hale Sayan V Haktan Ozacmak Aysel Guven R Gulhan Aktas I Diler Ozacmak 《Journal of investigative surgery》2006,19(3):163-173
Erythropoietin exerts hematopoietic effects by stimulating proliferation of early erythroid precursors. Nonhematopoietic effects of erythropoietin have also been shown. It may act as a new angiogenic factor in wound healing. This study aimed to investigate the effect of systemic administration of recombinant human erythropoietin on wound healing in mice. Dorsal incisional wounds were performed in mice, which were then divided into two groups; a group treated for 7 days with recombinant human erythropoietin, and a control group. Sacrificing animals on day 7, the wound tissues were collected for analysis of wound breaking strength, malondialdehyde, a marker of lipid peroxidation, hydroxyproline, an index of reparative collagen deposition, reduced glutathione levels, and for histological evaluation. The immunohistochemical determination of vascular endothelial growth factor (VEGF) which is believed to be the most prevalent angiogenic factor throughout the skin repair process, was also studied. The treatment significantly increased wound breaking strength by decreasing malondialdehyde and increasing hydroxyproline levels on day 7 after wounding. No statistically meaningful change was observed in reduced glutathione content. VEGF was immunostained significantly more on wound tissue of treated animals compared to the control group. Recombinant human erythropoietin treatment may be effective in wound healing due to inhibition of lipid peroxidation, deposition of collagen, and VEGF expression in wound area. 相似文献
3.
Formulation and in Vitro-in Vivo Evaluation of Sustained-Release Lithium Carbonate Tablets 总被引:1,自引:0,他引:1
Çiftçi Kadriye Çapan Yilmaz Öztürk Orhan Hincal A. Atilla 《Pharmaceutical research》1990,7(4):359-363
The release of lithium carbonate incorporated into polymethylmethacrylate, poly vinyl chloride, hy-drogenated vegetable oil, and carbomer matrix tablets was studied in vitro. The formulation containing 10% carbomer showed a sustained-release profile comparable to that of a standard, commercially available, sustained-release preparation containing 400 mg lithium carbonate embedded in a composite material. In vivo the newly formulated and standard sustained-release lithium carbonate tablets were compared to an oral solution and conventional lithium carbonate tablets in 12 healthy subjects. These crossover studies showed that the sustained-release tablets produced a flatter serum concentration curve than the oral solution and conventional tablet, without loss of total bioavailability. 相似文献
4.
Christoph R?cken Jutta Ernst Ernst Hund Hartmut Michels Jolanta Perz Wolfgang Saeger Orhan Sezer Simone Spuler Friedrich Willig und Hartmut H.-J. Schmidt 《Medizinische Klinik》2006,101(10):825-829
Ohne Zusammenfassung 相似文献
5.
6.
Engin Altinta? Dilek O?uz Sabite Ka?ar Yasemin Ozderin Orhan Sezgin Neslihan Inci Zengin 《The Turkish journal of gastroenterology》2004,15(1):49-52
Dydrogesterone, similar to women's natural progesterone, has been used in a wide range of gynecological conditions. Despite its widespread use, dydrogesterone-induced hepatotoxicity and dydrogesterone-induced hemolytic anemia have, to the best of our knowledge, never been reported previously. We describe a case of hepatitis and warm antibody hemolytic anemia due to dydrogesterone. 相似文献
7.
8.
Misdiagnosed fibrosarcoma of the mandible mimicking temporomandibular disorder: a rare condition. 总被引:1,自引:0,他引:1
Kaan Orhan Ay?e Isil Orhan Ula? Oz Filiz Namdar Pekiner Cagri Delilbasi 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,104(4):e26-e29
The jawbones can be sites of various neoplastic conditions. Given the variety of processes affecting this particular anatomical area, formulation of a precise diagnosis can be challenging to clinicians. Limited jaw movement, pain, and facial asymmetry are common signs among patients, especially those with temporomandibular disorder (TMD). This paper reports a case of primary fibrosarcoma affecting the mandible and surrounding structures in a 14-year-old girl presenting signs and symptoms similar to TMD. Her condition was misdiagnosed, and she was treated for TMD over an extended period before the correct diagnosis was made for fibrosarcoma. The patient underwent surgical resection with postsurgical radiotherapy and chemotherapy and now is being followed up. Although malignant lesions are rare in the temporomandibular joint (TMJ) region, dentists are advised to be aware of the condition and to keep in mind that patients who are admitting for TMD can also possibly be affected from neoplasms. Hence, those patients have to be examined meticulously to avoid misdiagnosis and mistreatment. 相似文献
9.
10.
The Human Leukocyte Antigen (HLA) typing of large groups of patients with various autoimmune diseases has demonstrated that some HLA alleles occur at higher frequencies in specific diseases than in the general population. Chronic urticaria has been shown to have an autoimmune basis by a previous study which found an association between chronic urticaria and specific HLA groups. We investigated the HLA subtypes of Turkish chronic urticaria patients. For this purpose 42 Turkish patients with chronic urticaria and 115 healthy controls were typed for HLA-DR and DQ by PCR-SSP (Polymerase Chain Reaction Sequence Specific Primers) low resolution DNA technique. We found an increased frequency of DR4 (42.9%, p=0.01) in chronic urticaria patients in comparison with that in healthy controls. This study supports the hypothesis that HLA alleles may be involved in the pathogenesis of chronic urticaria and that they appear to be directly involved in the initiation of the immune response. 相似文献