全文获取类型
收费全文 | 28158篇 |
免费 | 1884篇 |
国内免费 | 98篇 |
专业分类
耳鼻咽喉 | 216篇 |
儿科学 | 796篇 |
妇产科学 | 608篇 |
基础医学 | 4739篇 |
口腔科学 | 754篇 |
临床医学 | 2730篇 |
内科学 | 5352篇 |
皮肤病学 | 563篇 |
神经病学 | 2795篇 |
特种医学 | 727篇 |
外国民族医学 | 2篇 |
外科学 | 2844篇 |
综合类 | 149篇 |
一般理论 | 28篇 |
预防医学 | 2836篇 |
眼科学 | 415篇 |
药学 | 1798篇 |
中国医学 | 48篇 |
肿瘤学 | 2740篇 |
出版年
2023年 | 204篇 |
2022年 | 371篇 |
2021年 | 688篇 |
2020年 | 495篇 |
2019年 | 685篇 |
2018年 | 789篇 |
2017年 | 645篇 |
2016年 | 726篇 |
2015年 | 812篇 |
2014年 | 1003篇 |
2013年 | 1422篇 |
2012年 | 1967篇 |
2011年 | 1963篇 |
2010年 | 1134篇 |
2009年 | 1051篇 |
2008年 | 1771篇 |
2007年 | 1718篇 |
2006年 | 1628篇 |
2005年 | 1546篇 |
2004年 | 1344篇 |
2003年 | 1377篇 |
2002年 | 1240篇 |
2001年 | 373篇 |
2000年 | 330篇 |
1999年 | 340篇 |
1998年 | 258篇 |
1997年 | 258篇 |
1996年 | 200篇 |
1995年 | 213篇 |
1994年 | 176篇 |
1993年 | 168篇 |
1992年 | 223篇 |
1991年 | 237篇 |
1990年 | 197篇 |
1989年 | 183篇 |
1988年 | 175篇 |
1987年 | 165篇 |
1986年 | 167篇 |
1985年 | 141篇 |
1984年 | 162篇 |
1983年 | 116篇 |
1982年 | 126篇 |
1981年 | 103篇 |
1980年 | 93篇 |
1979年 | 95篇 |
1978年 | 103篇 |
1976年 | 77篇 |
1975年 | 96篇 |
1974年 | 95篇 |
1973年 | 77篇 |
排序方式: 共有10000条查询结果,搜索用时 15 毫秒
1.
2.
María Cabrerizo Gloria Trallero María José Pena Amaia Cilla Gregoria Megias Carmen Mu?oz-Almagro Eva Del Amo Diana Roda Ana Isabel Mensalvas Antonio Moreno-Docón Juan García-Costa Nuria Rabella Manuel Ome?aca María Pilar Romero Sara Sanbonmatsu-Gámez Mercedes Pérez-Ruiz María José Santos-Mu?oz Cristina Calvo And the study group of “Enterovirus parechovirus infections in children under ?years-old Spain” PI- 《European journal of pediatrics》2015,174(11):1511-1516
3.
H. Nilsson J. Johansson K. Svanberg S. Svanberg G. Jori E. Reddi A. Segalla D. Gust A. L. Moore T. A. Moore 《British journal of cancer》1997,76(3):355-364
The biodistribution of two recently developed tumour markers, trimethylated (CP(Me)3) and trimethoxylated (CP(OMe)3) carotenoporphyrin, was investigated by means of laser-induced fluorescence (LIF) after i.v. injection into 38 tumour-bearing (MS-2 fibrosarcoma) female Balb/c mice. At 3, 24, 48 or 96 h after administration, the carotenoporphyrin fluorescence was measured in tumoral and peritumoral tissue, as well as in the abdominal, thoracic and cranial cavities. The fluorescence was induced by a nitrogen laser-pumped dye laser, emitting light at 425 nm, and analysed by a polychromator equipped with an image-intensified CCD camera. The fluorescence was evaluated at 490, 655 and 720 nm: the second and third wavelengths represent the carotenoporphyrin (CP)-related peaks, whereas the first one is close to the peak of the tissue autofluorescence. The tumour and the liver were the two tissue types showing the strongest carotenoporphyrin-related fluorescence, whereas the cerebral cortex and muscle consistently exhibited weak substance-related fluorescence. In most tissue types, the fluorescence intensities decreased over time. A few exceptions were observed, notably the liver, in which the intensity remained remarkably constant over the time period investigated. 相似文献
4.
Long-term neurotoxicity of chlorpyrifos: spatial learning impairment on repeated acquisition in a water maze. 总被引:2,自引:0,他引:2
Fernando Ca?adas Diana Cardona Eva Dávila Fernando Sánchez-Santed 《Toxicological sciences》2005,85(2):944-951
Organophosphate compounds are cholinesterase inhibitors widely used in agriculture, industry, household products, and even as chemical weapons. Their major mechanism of acute toxic action is the inhibition of acetylcholinesterase, which is responsible for the degradation of the neurotransmitter acetylcholine. An organophosphorus ester-induced chronic neurotoxicity (OPICN) syndrome has been proposed. The OPICN syndrome could result from both long-term exposure to subclinical doses of OPs and after acute poisoning. Development of animal models for the cognitive decline are required and could later help to elucidate the mechanisms involved in this long-term effect on the central nervous system. Previously, we have found performance decrements in a four-trial repeated acquisition spatial task in a water maze. The present study includes two experiments to extend the long-term behavioral effects observed. Rats were injected either once or twice with chlorpyrifos (CPF) and then tested months after in a two-trial repeated acquisition task in a water maze. Our results confirm and extend the long-term behavioral effects of subcutaneous administration of CPF. The two treatments used produced performance decrements that suggest functional central nervous system alterations. 相似文献
5.
6.
7.
8.
Nonconvulsive status epilepticus may be subdivided into generalized (absence) status and complex partial status. The latter is regarded as a rarity, whereas the former constitutes the dominant part of the hitherto reported cases. We report 10 consecutive cases of adult patients with nonconvulsive status epilepticus, all documented by ictal electroencephalographic (EEG) recordings. Five had a complex partial status; the origin of the complex partial status appeared to be frontal in four of these patients. Three had recurrent complex partial seizures with incomplete recovery between seizures, and two had more continuous symptoms. One of the latter exhibited neither motor phenomena nor automatisms. The effect of diazepam or clonazepam was immediate in all 10 cases though transient in eight. A lasting control of the status was not achieved in six patients until i.v. phenytoin was added. The difficulties in the differentiation between complex partial status and absence status despite ictal EEG recordings are discussed, illustrated by a case with seizure discharges of a focal onset which rapidly generalized. The study indicates that complex partial status may be more common and the clinical expressions of absence status more variable than hitherto recognized. 相似文献
9.
Ophira Salomon Joseph Moisseiev Tamara Vilganski Rima Dardik Shimon Kurtz Eva Shpringer David M Steinberg Nurit Rosenberg 《Blood coagulation & fibrinolysis》2006,17(6):485-488
To determine whether polymorphisms of platelet surface glycoprotein associated with arterial thrombosis are risk factors for branch retinal vein occlusion. A case-control study in which 69 patients with branch retinal vein occlusion and 147 controls who attended the eye clinic for nonvascular complications participated. DNA was extracted from whole blood and analyzed for genotyping of platelet glycoprotein polymorphisms by polymerase chain reactions and specific restricted enzymes. No relationship was found between the four platelet glycoprotein polymorphisms i.e. GPIa C807T, VNTR and Kozak of glycoprotein Ibalpha, the HPA-1 of glycoprotein IIIa and the occurrence of branch retinal vein occlusion. The HPA-2 polymorphism was found in 18 out 60 (30%) patients with branch retinal vein occlusion in comparison with 27 out 142 (19%) of controls, with an estimated odds ratio of 1.8 (95% confidence interval, 0.91-3.65). The four platelet glycoprotein polymorphisms are not risk factors for branch retinal vein occlusion and therefore it seems unnecessary to screen those patients for it. A larger study is required, however, to determine whether HPA-2 is a novel risk factor for branch retinal vein occlusion. 相似文献
10.
Michael Schenker Mikael Wiberg Simon P Kay Roland S Johansson 《Journal of plastic, reconstructive & aesthetic surgery》2007,60(1):13-23
Although toe-to-hand transfer has a defined role in the management of congenital hand deformities, it remains unclear how well children integrate the transferred digits into physiological grasping. We analysed fingertip forces in the precision grip of 13 patients when lifting a test object more than three years after free toe transfer for absent or hypoplastic digits. Clinically, most patients showed normal sensibility of transferred digits, but active motion and pinch strength were limited as compared to the normal hand. For the control of fingertip forces, two key features of the normal two-digit opposition grip were seen in all operated hands: adaptation of grip force to object weight and parallel coordination of lift and grip forces. These physiological grasping strategies developed independently of the patients' age at the time of operation, which ranged from one to 13 years. In four patients, we observed increased tangential load forces with the operated hand due to misalignments in the application of fingertips on the grasp surfaces. Such forces lead to increased grip force requirements on both fingers that may overload transferred digits with limited motor function. The need for optimal alignment of the grip axis during toe-transfer surgery is emphasised. 相似文献