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排序方式: 共有143条查询结果,搜索用时 0 毫秒
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B. Bader-Meunier C. Gitiaux A. Belot K. Brochard R. Mouy D. Ponce V. Bughin F. Jouen L. Musset Y. Allenbach E. Hachulla H. Maillard A. Meyer E. Bourrat O. Benveniste 《Archives de pédiatrie》2019,26(2):120-125
A guideline group consisting of a pediatric rheumatologist, internists, rheumatologists, immunologists, a physiotherapist and a patient expert elaborated guidelines related to the management of juvenile dermatomyositis on behalf of the rare autoimmune and autoinflammatory diseases network FAI2R. A systematic search of the literature published between 2000 and 2015 and indexed in PubMed was undertaken. Here, we present the expert opinion for diagnosis and treatment in juvenile dermatomyositis. 相似文献
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E. David A. Belot J.-C. Lega I. Durieu C. Rousset-Jablonski 《La Revue de médecine interne / fondée ... par la Société nationale francaise de médecine interne》2021,42(7):498-504
Infection with human papillomavirus (HPV) is one of the most widespread sexually transmitted diseases and the main risk factor for cervical cancer. Underlying conditions, like immunosuppression, favour the persistence and the progression of cervical lesions to an aggressive form. Patients with autoimmune diseases, and particularly systemic lupus erythematosus (SLE), may be prone to HPV infection and cervical dysplasia. However, the risk factors for developing persistent HPV-related infection, dysplasia and cancer are not identified for patients with SLE. The existence of an increased risk of cervical cancer compared to the general population remains debated. Thus, HPV vaccine is recommended for SLE patients as well as for the general population. Vaccine coverage of SLE patients is not known in France. Adolescents with chronic health condition seem to be insufficiently vaccinated regarding their vulnerability to infectious diseases. Strategies are required to decrease HPV vaccination barriers. 相似文献
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Ellia Mezgueldi Aurlia Bertholet‐Thomas Solange Milazzo Michael Morris Justine Bacchetta Nicole Fabien Pierre Cochat Anthony P. Weetman Elizabeth Helen Kemp Alexandre Belot 《Clinical Case Reports》2015,3(10):809-813
Early diagnosis of potentially life‐threatening autoimmune polyendocrinopathy‐candidiasis‐ectodermal dystrophy (APECED) is crucial, but is often delayed due to the clinical heterogeneity of the disorder. Even in the absence of the classic disease triad of chronic mucocutaneous candidiasis, hypoparathyroidism, and adrenocortical insufficiency, a diagnosis of APECED should be considered in children who have hypoparathyroidism and chronic keratitis, with a past medical history showing a mild and transient Candida infection. 相似文献
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Vincent Goëb Marc Ardizzone Laurent Arnaud Jérôme Avouac Athan Baillet Alexandre Belot Béatrice Bouvard Pascal Coquerelle Sabrina Dadoun Alain Diguet David Launay Danielle Lebouc Pierre Loulergue Sophie Mahy Pascal Mestat Gaël Mouterde Benjamin Terrier Coralie Varoquier Jean Sibilia 《Revue du Rhumatisme》2013,80(5):459-466
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Douay N Belot F Bader G Guyot B Heitz D Fauconnier A 《Gynécologie, obstétrique & fertilité》2007,35(7-8):632-636
OBJECTIVES: The purpose of the study was to compare the postoperative pain of patients who had a hysterectomy through vaginal route according to the process of binding: wire or electrosurgical bipolar vessel sealing. PATIENTS AND METHODS: Retrospective study carried out in the 60 last patients who underwent a hysterectomy by vaginal route for a benign pathology in the gynaecological service of surgery of the CHI Poissy-Saint-Germain-en-Laye until March 2006. Among these patients, 32 had profited from a binding by wire and 28 of the electrosurgical bipolar vessel sealing. The studied criteria were the post-operative pain, total morphine consumption and the durations of the analgesic treatment, the hospitalisation and intervention time. RESULTS: The postoperative pain in the first 24 hours was twice lower using thermofusion; it was valid in immediate post-operative period and after 24 hours. In addition, total morphine consumption was also significantly lower using thermofusion. DISCUSSION AND CONCLUSION: This pilot study shows that the electrosurgical bipolar vessel sealing allows a reduction in the pain into the immediate postoperative period. Other prospective and randomised studies would allow it and conclude on the duration of hospitalisation, the quality of life from the patients and the cost in terms of public health. 相似文献
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Galectin-1 modulates human glioblastoma cell migration into the brain through modifications to the actin cytoskeleton and levels of expression of small GTPases 总被引:10,自引:0,他引:10
Camby I Belot N Lefranc F Sadeghi N de Launoit Y Kaltner H Musette S Darro F Danguy A Salmon I Gabius HJ Kiss R 《Journal of neuropathology and experimental neurology》2002,61(7):585-596
We show that high-grade astrocytic tumors with high levels of galectin-1 expression are associated with dismal prognoses. The immunohistochemical analysis of galectin-1 expression of human U87 and U373 glioblastoma xenografts from the brains of nude mice revealed a higher level of galectin-1 expression in invasive areas rather than non-invasive areas of the xenografts. Nude mice intracranially grafted with U87 or U373 cells constitutively expressing low levels of galectin-1 (by stable transfection of an expression vector containing the antisense mRNA of galectin-1) had longer survival periods than those grafted with U87 or U373 cells expressing normal levels of galectin-1. Galectin-1 added to the culture media markedly and specifically increased cell motility levels in human neoplastic astrocytes. These effects are related to marked modifications in the organization of the actin cytoskeleton and the increase in small GTPase RhoA expression. All the data obtained indicate that galectin-1 enhances the migratory capabilities of tumor astrocytes and, therefore, their biological aggressiveness. 相似文献