全文获取类型
收费全文 | 2709篇 |
免费 | 111篇 |
专业分类
耳鼻咽喉 | 19篇 |
儿科学 | 119篇 |
妇产科学 | 27篇 |
基础医学 | 335篇 |
口腔科学 | 31篇 |
临床医学 | 181篇 |
内科学 | 562篇 |
皮肤病学 | 58篇 |
神经病学 | 298篇 |
特种医学 | 101篇 |
外科学 | 329篇 |
综合类 | 42篇 |
预防医学 | 114篇 |
眼科学 | 171篇 |
药学 | 137篇 |
中国医学 | 3篇 |
肿瘤学 | 293篇 |
出版年
2023年 | 21篇 |
2022年 | 54篇 |
2021年 | 104篇 |
2020年 | 62篇 |
2019年 | 64篇 |
2018年 | 96篇 |
2017年 | 54篇 |
2016年 | 51篇 |
2015年 | 62篇 |
2014年 | 89篇 |
2013年 | 124篇 |
2012年 | 185篇 |
2011年 | 184篇 |
2010年 | 97篇 |
2009年 | 91篇 |
2008年 | 146篇 |
2007年 | 158篇 |
2006年 | 138篇 |
2005年 | 112篇 |
2004年 | 139篇 |
2003年 | 128篇 |
2002年 | 84篇 |
2001年 | 43篇 |
2000年 | 62篇 |
1999年 | 58篇 |
1998年 | 15篇 |
1997年 | 14篇 |
1996年 | 16篇 |
1995年 | 11篇 |
1994年 | 17篇 |
1993年 | 12篇 |
1992年 | 26篇 |
1991年 | 29篇 |
1990年 | 20篇 |
1989年 | 21篇 |
1988年 | 27篇 |
1987年 | 36篇 |
1986年 | 26篇 |
1985年 | 22篇 |
1984年 | 13篇 |
1983年 | 9篇 |
1982年 | 8篇 |
1980年 | 5篇 |
1979年 | 10篇 |
1977年 | 5篇 |
1975年 | 8篇 |
1973年 | 10篇 |
1972年 | 13篇 |
1971年 | 13篇 |
1970年 | 5篇 |
排序方式: 共有2820条查询结果,搜索用时 527 毫秒
1.
2.
3.
Scott E Strome Elizabeth Martin Dallas Flies Dianne Khurana Diva Salomao Koji Tamada Andrei I Chapoval Jan L Kasperbauer Kerry D Olsen Lieping Chen 《Otolaryngology--head and neck surgery》2002,126(2):180-187
OBJECTIVES: CD62L was evaluated as a determinant of human pre-effector T cells. STUDY DESIGN AND SETTING: Phenotype and cytokine secretion profiles of CD62L cells were determined based on activation status. RESULTS: CD62L(Low) T cells demonstrated significantly higher secretion of interleukin (IL)-10 and interferon (IFN)-gamma than did CD62L(High) T cells. After activation, the majority of cells expressed high levels of the CD62L surface marker. Postactivation levels of IL-10 production remained elevated or unchanged. In a murine B16 melanoma model, freshly isolated CD62L(Low) tumor draining lymph nodes (TDLN) T cells showed increased secretion of IL-2 and IL-4 but not of IL-10 or IFN-gamma. The surface expression of CD62L and cytokine secretion patterns were maintained after activation with concomitant increases in IL-10. CONCLUSION: Our results provide evidence that CD62L(Low) T cells in TDLNs of progressively growing squamous cell carcinoma of the head and neck differ phenotypically and functionally from those of mouse origin. SIGNIFICANCE: Characterization of this human CD62L(Low) T cell population provides initial insight regarding novel surface markers in TDLN T cells that might correlate with antitumor reactivity. 相似文献
4.
Dipti Mahajan Nita Khurana Namrata Setia 《Oral surgery, oral medicine, oral pathology, oral radiology, and endodontics》2007,103(3):e47-e50
Cysticercosis is a parasitic infestation caused by the pork tapeworm larval stage, Cysticercus cellulosae. The majority of the cases present in ocular, cerebral, and subcutaneous locations. We report the presence of cysticercosis inside the submandibular gland in association with squamous cell carcinoma of the inferior alveolar ramus of the mandible. To the best of our knowledge, this is the first case report documenting cysticercosis inside a salivary gland. A 65-year-old male presented with complaints of an ulcerative lesion on the inferior alveolar ramus present for 2 months. Histological examination revealed a keratinizing well-differentiated squamous cell carcinoma involving the alveolar margin and mandible. The histopathological examination of the submandibular gland revealed cysticercosis. This case emphasizes the importance of adequate sampling of all the tissues obtained for associated infectious disorders, more so in immunosuppressed patients, which will help the clinician to manage the case appropriately. 相似文献
5.
Gahan J Pandina Robert Bilder Philip D Harvey Richard S E Keefe Michael G Aman Georges Gharabawi 《Neuropsychopharmacology》2007,62(3):226-234
BACKGROUND: Effects of risperidone on cognitive function in children with disruptive behavior disorders (DBDs) and subaverage intelligence quotient (IQ) were assessed. METHODS: Data from two 6-week, double-blind, placebo-controlled studies (n = 228) were combined, as were three 1-year, open-label studies (n = 688). Patients with DBDs and subaverage IQ, 5 to14 years, received placebo or risperidone .02 to .06 mg/kg/day. Cognitive measures included the Continuous Performance Task (CPT) and Verbal Learning Test for Children (VLT-C). Efficacy was assessed using the Nisonger Child Behavior Rating Form (NCBRF). Adverse events were collected via spontaneous report; sedation was assessed using visual analog scale. RESULTS: Improvements on the NCBRF Conduct Problem subscale were significantly greater for risperidone- versus placebo-treated patients (-15.8 vs. -6.4, p < .0001) in short-term studies; significant reductions were observed in long-term studies (-16.3, p < .0001). No overall decline and some significant improvement in attention (CPT) and memory (VLT-C) were noted regardless of treatment in short-term studies. VLT-C improved significantly (p < .0001) for both groups, with no difference between treatment groups. Improvements in memory (VLT-C) and attention (CPT) were noted in long-term studies. Somnolence/sedation did not affect cognitive function. CONCLUSIONS: Cognitive function was not altered by risperidone in short-term studies and was maintained or improved with one year of treatment in children with DBDs and subaverage IQ, potentially representing age-appropriate gains. 相似文献
6.
Ruma Pahwa Nita Khurana K Uma Chaturvedi Anoop Raj 《Indian journal of otolaryngology and head and neck surgery》2003,55(3):193-194
Neurilemmoma is usually soimry, benign tumour derived from schwan cells of the Sheaths of peripheral cranial or autonomie
nerves. In thehead and neck region it occurs most commonly in association with acoustic nerve within the skuil and is rely
fottnd in the oral cavity (1,2). We report here two cases of the iongue diagnosed on histopathohgy. 相似文献
7.
8.
W Mayo-Smith A E Rosenberg J S Khurana S V Kattapuram L H Romero 《Clinical orthopaedics and related research》1990,(251):230-234
Chondroblastoma, a rare bone tumor usually found in the epiphyseal region of long bones, appeared in the rib of a 49-year-old man. Review of the literature reveals that the most common locations for this tumor are the knee and proximal humerus. The most common age group is the second decade. Eighteen cases of chondroblastoma of the rib have been reported in the literature; the patients were older than typical patients with epiphyseal chondroblastoma and had an excellent prognosis after resection of the tumor. 相似文献
9.
Aman SHARMA Susheel KUMAR Ajay WANCHU A. K. MANDAL Surjit SINGH Pradeep BAMBERY 《International journal of rheumatic diseases》2007,10(2):153-155
Inflammatory myopathies like dermatomyositis are associated with increased incidence of malignancies. This association has been commonly reported with malignancies of ovaries, gastro‐intestinal tract, breast and non‐Hodgkin's lymphomas but occurrence of dermatomyositis with bladder cancer has been rarely reported. We report a patient with carcinoma bladder who developed dermatomyositis while being treated for the bladder cancer. 相似文献
10.
Scores for 112 children aged 6 to 12 years, with well-controlled seizures and of average or higher IQ, were compared for problem behavior with established norms. As assessed on the Conners' Teacher Rating Scale, the group with seizures was comparable to the normative group on two subscales and superior on two others. In contrast, parents of children in the seizure group rated them as significantly worse on all six subscales of the Revised Behavior Problem Checklist. In a larger group of 133 children with seizures, from which this sample was selected, the relationship of age, sex, and seizure type to behavior problems was examined. Subjects with partial seizures were rated as slightly more aggressive and antisocial than those with generalized seizures. Findings were discussed in regard to differences in perception of behavior by parents and teachers and the possible relevance of seizure type to the expression of behavior problems. 相似文献