低位腹主动脉血管外阻断下子宫成形术及改良Cho缝合术在凶险性前置胎盘伴胎盘植入剖宫产术中的联合应用价值

目的:探讨低位腹主动脉血管外阻断下子宫成形术及改良Cho缝合术在凶险性前置胎盘伴胎盘植入剖宫产术中的联合应用价值。方法:选择2017年1月1日至2019年2月28日于湖南省妇幼保健院进行择期剖宫产的凶险性前置胎盘伴穿透性胎盘植入并行低位腹主动脉血管外阻断术的27例患者进行回顾性分析,研究组行改良Cho缝合,在子宫下段胎盘穿透入处取第二横切口并修剪子宫重塑成形,共15例,对照组取子宫体部单切口,局部予常规\"U\"或\"8\"字缝合,共12例。结果:研究组中术中失血量≥2000 ml者比例少于对照组(20.0%vs 66.7%,P0.05),手术时间≥3小时比例低于对照组(33.3%vs 83.3%,P0.05),术后住院时间≥7天比例低于对照组(53.3%vs 91.7%,P0.05)。两组术中切除子宫各1例(P0.05),均未有非计划再次手术切除子宫及败血症发生。研究组1例膀胱修补,对照组2例膀胱修补(P0.05)。研究组腹壁伤口愈合不良2例,对照组1例(P0.05)。两组患者术后1～3月随访超声检查均无异常,均无其他器官系统后遗症及血栓发生。结论:低位腹主动脉血管外阻断下子宫成形术及改良Cho缝合可联合应用于凶险性前置胎盘伴穿透性胎盘植入患者的剖宫产术中,手术时间缩短,失血量下降,安全有效。     

经子宫后路子宫切除治疗穿透性胎盘植入2例报告

胎盘植入尤其是合并前置胎盘时常引起灾难性产后出血、术后感染、DIC等导致孕产妇死亡,是产科少见而严重的并发症,也是近年来围产期子宫切除最常见的手术指征。但是,由于子宫-膀胱腹膜粘连,子宫切除时下推膀胱困难,手术常发生严重并发症。近期我们采取了经子宫后路子宫切除方法,减少出血量且未发生手术严重并发症,现介绍如下。     

腹主动脉球囊阻断术联合子宫重塑术对凶险性前置胎盘并发胎盘植入患者产后出血、子宫切除的影响及安全性分析

目的 探讨腹主动脉球囊阻断术联合子宫重塑术对凶险性前置胎盘并发胎盘植入患者产后出血、子宫切除的影响及安全性.方法 2017年10月至2019年10月河南省驻马店市中心医院收治的68例凶险性前置胎盘并发胎盘植入患者随机分为治疗组及对照组,各34例.对照组剖宫产术前行腹主动脉球囊阻断术,治疗组在对照组基础上联合子宫重塑术,...     

腹主动脉球囊阻断在凶险性前置胎盘合并胎盘植入剖宫产术中的应用

目的:探讨凶险性前置胎盘合并胎盘植入术前行腹主动脉球囊导管预置术,术中暂时阻断腹主动脉后其对剖宫产术中出血及相关并发症的影响。方法:回顾性分析郑州大学第一附属医院2012年1月至2015年6月在产科住院分娩的凶险性前置胎盘合并大面积穿透性胎盘植入病例268例,A组230例剖宫产术前行腹主动脉球囊导管预置术,术中暂时阻断腹主动脉血流,B组38例术前未行腹主动脉球囊导管预置术,比较两组术中、术后情况及其相关并发症差异。结果:A组手术时间、术中出血量、术中输血量、术中检测PT值、子宫切除率及术后转重症监护病房率均明显低于B组,差异有统计学意义(P0.05);两组新生儿Apgar评分、出生体质量比较,差异无统计学意义(P0.05)。结论:凶险性前置胎盘合并大面积穿透性胎盘植入,剖宫产术前行腹主动脉球囊导管预置术,可有效减少术中出血,降低子宫切除等相关并发症的风险。     

腹主动脉球囊阻断术用于凶险性前置胎盘合并胎盘植入剖宫产术的并发症及处理

目的:探讨腹主动脉球囊阻断术应用于凶险性前置胎盘合并胎盘植入的孕妇剖宫产手术中的并发症和处理.方法:回顾分析2017年1月1日至2017年12月31日在郑州大学第三附属医院住院分娩的凶险性前置胎盘伴胎盘植入患者166例,均行腹主动脉球囊阻断下剖宫产术.统计球囊阻断术的手术成功率、手术时间、术中出血量,观察术后球囊置入介...     

经子宫后路子宫切除术在凶险性前置胎盘伴胎盘植入中的临床应用

目的:探讨经子宫后路子宫切除术在凶险性前置胎盘伴胎盘植入中的临床应用价值。方法:对经临床或病理诊断凶险性前置胎盘伴胎盘植入患者90例分为经子宫后路子宫切除术组(观察组)23例和传统子宫切除术组(对照组)67例,对比两组平均手术时间、术中出血量、术后24小时出血量、术后住院天数、严重并发症。结果:观察组无孕产妇死亡,对照组1例孕产妇死亡。观察组未发生膀胱损伤,1例(4.34%)输尿管损伤、1例(4.34%)肠管损伤;对照组5例(7.46%)膀胱损伤,7例(10.4%)输尿管损伤、7例(10.4%)肠管损伤;两组各并发症比较差异均有统计学意义(P0.05)。观察组与对照组比较,手术平均时间(143.7±40.5分钟vs 180.8±37.2分钟)、术中出血量及术后24小时出血量(2243.6±1010.7 ml vs 2866.5±985.9 ml,2468.5±120.7 ml vs 3084.1±110.5 ml)、输注红细胞量(12.3±5.6 U vs 17.1±6.7 U)、术后住院天数(7.8±3.2天vs 10.7±2.9天)差异有统计学意义(P0.05)。结论:经子宫后路子宫切除术治疗凶险性前置胎盘伴胎盘植入,能有效控制产后出血量,减少手术并发症,可能是更好的手术选择。     

不同动脉阻断术在凶险性前置胎盘伴胎盘植入剖宫产中的应用比较

目的:比较腹主动脉球囊阻断术、双侧髂内动脉球囊阻断术和子宫动脉栓塞术3种不同动脉阻断术在凶险性前置胎盘伴胎盘植入产妇剖宫产中的效果。方法:回顾性分析2014年10月至2017年12月在武汉中心医院剖宫产分娩的103例凶险性前置胎盘伴胎盘植入产妇的临床资料,分为子宫动脉栓塞术组(UA组,n=30),腹主动脉球囊阻断术组(AA组,n=34)和双侧髂内动脉球囊阻断术组(IA组,n=39)。比较3组产妇置管情况,剖宫产手术情况及产后情况。结果:3组产妇剖宫产术前置管术时间两两比较,差异均有统计学意义(P<0.05),UA组最短为5.32±2.34分钟,IA组最长为32.18±6.31分钟。UA组胎儿基本未受辐射,AA组胎儿透视时间和接受辐射量显著少于IA组,差异有统计学意义(9.48±3.21秒vs 54.23±23.85秒,t=10.846,P=0.000;2.94±0.78 mGY vs 21.29±13.84 mGY,t=7.714,P=0.000)。3组产妇剖宫产情况比较:UA组手术时间最长(143.45±25.43分钟),AA组手术时间最短(104.23±21.38分钟);UA组的术中出血量、输血比率、输血量及子宫切除率显著高于其他两组(P<0.05);UA组产后血红蛋白浓度显著低于其他两组(P<0.05)。3组产妇剖宫产术后情况比较,差异无统计学意义(P>0.05)。结论:腹主动脉和髂内动脉球囊术对凶险性前置胎盘伴胎盘植入产妇剖宫产术中出血控制效果较好,子宫保留率更高。腹主动脉球囊阻断术对母体和胎儿的放射安全性更好。     

腹主动脉球囊阻断辅助下提拉宫颈行子宫下段螺旋式缝合术在植入型凶险型前置胎盘中的应用

目的:对植入型凶险型前置胎盘的孕妇,计划性剖宫产术中采用腹主动脉球囊阻断辅助下提拉宫颈,行子宫下段螺旋式缝合术的有效性和安全性进行评估。方法:选取18例经B型彩色超声和磁共振成像(MRI)联合诊断为植入型凶险型前置胎盘的孕妇,均行计划性剖宫产(保留子宫意愿),手术孕周(36.78±1.63)周。剖宫产术前行腹主动脉球囊预置管,娩出胎儿并结扎脐带后,采用腹主动脉球囊临时阻断,剥离胎盘,提拉宫颈,行子宫下段螺旋式缝合术。术后必要时行双侧子宫动脉栓塞术。回顾分析患者的术中失血量、术后24h失血量、子宫切除率、输血量、预置腹主动脉球囊时间、腹主动脉球囊阻断时间、胎儿和产妇的辐射剂量、术后血管并发症、外科并发症及产褥期并发症。结果:18例孕妇术中视诊和术后病理均诊断为凶险型前置胎盘伴胎盘植入。剖宫产术中失血量(2061±1709)ml,术后24h失血量(228±141)ml,子宫切除率5.55%,12例输血,输注红细胞悬液量(1148±1061)ml,血浆量(491±403)ml。腹主动脉球囊预置管时间为(4.17±1.25)min,腹主动脉球囊阻断时间为(15.83±8.01)min;胎儿辐射剂量(9±5.50)mGy,产妇辐射剂量(43.29±47.64)mGy。外科并发症1例(膀胱损伤),无血管并发症和产褥期并发症发生。结论:腹主动脉球囊阻断辅助下提拉宫颈行子宫下段螺旋式缝合术是控制植入型凶险型前置胎盘患者术中、术后出血与保留子宫的一种安全和有效的联合治疗方法。     

腹主动脉球囊阻断辅助下提拉宫颈行子宫下段螺旋式缝合术在植入型凶险型前置胎盘中的应用26

目的:对植入型凶险型前置胎盘的孕妇,计划性剖宫产术中采用腹主动脉球囊阻断辅助下提拉宫颈,行子宫下段螺旋式缝合术的有效性和安全性进行评估.方法:选取18例经B型彩色超声和磁共振成像(MRI)联合诊断为植入型凶险型前置胎盘的孕妇,均行计划性剖宫产(保留子宫意愿),手术孕周(36.78±1.63)周.剖宫产术前行腹主动脉球囊预置管,娩出胎儿并结扎脐带后,采用腹主动脉球囊临时阻断,剥离胎盘,提拉宫颈,行子宫下段螺旋式缝合术.术后必要时行双侧子宫动脉栓塞术.回顾分析患者的术中失血量、术后24 h失血量、子宫切除率、输血量、预置腹主动脉球囊时间、腹主动脉球囊阻断时间、胎儿和产妇的辐射剂量、术后血管并发症、外科并发症及产褥期并发症.结果:18例孕妇术中视诊和术后病理均诊断为凶险型前置胎盘伴胎盘植入.剖宫产术中失血量(2061±1709)ml,术后24h失血量(228±141)ml,子宫切除率5.55%,12例输血,输注红细胞悬液量(1148±1061)ml,血浆量(491±403)ml.腹主动脉球囊预置管时间为(4.17±1.25)min,腹主动脉球囊阻断时间为(15.83±8.01)min;胎儿辐射剂量(9±5.50)mGy,产妇辐射剂量(43.29±47.64)mGy.外科并发症1例(膀胱损伤),无血管并发症和产褥期并发症发生.结论:腹主动脉球囊阻断辅助下提拉宫颈行子宫下段螺旋式缝合术是控制植入型凶险型前置胎盘患者术中、术后出血与保留子宫的一种安全和有效的联合治疗方法.     

剖宫产术后瘢痕部穿透性胎盘植入

剖宫产术后再次妊娠瘢痕部位穿透性胎盘植入可以发生在妊娠期的各个阶段,临床中常由于诊断延误或处理不当引起致命性难以控制的大出血而行子宫切除术,严重者直接导致胎儿及孕产妇的死亡。统计资料显示,我国的剖宫产率在20世纪80年代初为19．5％,到20世纪90年代上升为35．3％,近年来个别地区上升为50％以上。随着剖宫产率的上升,剖宫产后再次妊娠问题愈加引起关注。     

Clinical application of prophylactic internal iliac artery balloon occlusion combined with uterine artery embolization in patients with abnormally invasive placenta

Background: The purpose of this study is to investigate the role of prophylactic internal iliac artery balloon occlusion combined with uterine artery embolization (UAE) in patients with abnormally invasive placenta.

Methods: Forty cases with abnormally invasive placenta who visited our hospital were analyzed retrospectively from May 2014 to September 2015. Twenty cases who had prophylactic balloon occlusion of internal iliac artery with/without UAE were in the study group, while the other 20 cases in the control group. Volume of estimated blood loss and blood transfusion, rate of hysterectomy, surgery duration, postoperative complication and length of hospitalization were compared between two groups.

Results: The mean estimated blood loss in the study group (800?ml,500–1800?ml) was less than that in the control group (1875?ml, 500–7600?ml) (p?=?.01). Only two cases had blood transfusion in the study group, while 12 cases in the control group. No case was performed hysterectomy in the study group, while one case had the operation in the control group. There was no significant difference in surgery duration, postoperative complications and length of hospitalization between two groups.

Conclusion: Prophylactic balloon occlusion of internal iliac artery combined with UAE is effective and safe for patients with abnormally invasive placenta.     

Aortic balloon occlusion for controlling intraoperative hemorrhage in patients with placenta previa increta/percreta

Background/Aims: To investigate whether abdominal aortic balloon occlusion (ABO) effectively reduces intraoperative hemorrhage in patents with placenta previa increta/increta.

Methods: Forty-three women were diagnosed as placenta previa increta/percreta by ultrasound and MRI. These patients’ assessments were taken by their chief physician, and they were under necessity of previous cesarean section as confirmed by the committee of experts during consultation. There was no significant difference in disease risk rating between them in whole process. Although our department provided a more appropriate method, 10 of 43 patients chose intraoperative aortic balloon occlusion (IABO). Other 33 patients who refused that suggestion were considered as control group. Fully informed consents were obtained from all patients in this study group. The intraoperative blood loss, blood transfusion, rate of hysterectomy and complications of mothers and fetus of IABO group and control group were analyzed.

Results: The median intraoperative blood loss was 1000?ml in the IABO group compared with 2000?ml in the control group (p?<?0.05). The median volume of transfused red blood cells was 1100?ml in the IABO group compared with 2000?ml in the control group (p?<?0.05). 33.3% (11/33) patients in the control group had hemorrhagic shock, and one of them suffered from cardiac arrest intraoperatively because of severe bleeding. However, none of these serious events occurred in the IABO group (p?<?0.05). The hysterectomy rate was 70% (7/10) in the IABO group and 63.3% (21/33) in the control group (p?>?0.05). No IABO-related complications were observed in the mother and fetus.

Conclusion: IABO is an effective and safe method to control intraoperative blood loss and blood transfusion in patients with placenta previa increta/percreta.     

Effects of method of uterine repair on surgical outcome of cesarean delivery

Objective

To compare the rates of intraoperative and postoperative complications of uterine repair when performed in situ or extra-abdominally following cesarean delivery.

Methods

In this prospective randomized study 4925 women who underwent cesarean delivery were randomly assigned to in situ (n = 2462) or extra-abdominal (n = 2463) uterine repair (group 1 and group 2, respectively). The study compares drop in hemoglobin concentration (as a measure of intraoperative blood loss). It also compares operating time, time to return of bowel sound, and duration of hospitalization as well as rates of uterine atony, blood transfusion, intraoperative complications, additional use postoperative analgesics, endometritis, and wound infection.

Results

Uterine atony developed in 96 women (3.8%) in group 1 and 226 women (9.1%) in group 2 (P = 0.001). Moreover, the operating time and the time to return of bowel sound were shorter and the rates of both additional use of postoperative analgesics and wound infection were lower in group 1 (P = 0.001, P = 0.002, P = 0.001, and P = 0.003, respectively).

Conclusion

Fewer cases of uterine atony, a shorter operating time, a faster return of bowel function, a lesser need for postoperative analgesics, and lower rates of additional use of postoperative analgesics and wound infections suggest that in-situ uterine repair ought to be preferred to extra-abdominal uterine repair following cesarean delivery.     

Placement of a cervical cerclage in combination with an intrauterine balloon catheter to arrest postpartum hemorrhage

Placement of a cervical cerclage postpartum allows retention of a uterine tamponade balloon in women with a dilated cervix. This novel indication for a cervical cerclage may be a useful adjunct to intrauterine balloon catheter in management of postpartum uterine hemorrhage.     

Uterine balloon therapy for the treatment of menorrhagia

Objective(s)

To evaluate the effectiveness of uterine balloon therapy for the treatment of menorrhagia and to determine its prognostic factors.

Method(s)

Seventy five patients were treated with uterine balloon therapy with thermachoice II for intractable menorrhagia without detectable pathology and the results were statistically analyzed regarding procedure efficacy, safety, side effects and prognostic factors at follow-up periods of one month, three months, six months and 12 months.

Results(s)

After undergoing uterine balloon therapy, 41.30% patients attained eumenorrhea, 30.43% hypomenorrhea and 15.21% amenorrhea at the end of 12 months follow-up. Retroverted uterus, prolonged duration of menstruation, endometrial thickness of at least 9mm and uterine depth >10 cm were associated with an increased risk of treatment failure.

Conclusion(s)

Uterine balloon therapy is an efficient and reliable modality to treat women with intractable menorrhagia especially those who have completed their families but do not want to part with their uterus which of course is without any organic pathology.     

Depression of uterine blood flow during total umbilical cord occlusion in sheep

The effect of total umbilical cord occlusion upon maternal blood flow in the internal iliac and median uterine arteries was studied in eight chronically instrumented pregnant sheep. Occlusion of the umbilical cord was performed with an inflatable balloon occluder around the total cord. Blood flow was measured with electromagnetic flow transducers. Total umbilical cord occlusion of short duration (mean 40.1 s) caused a significant decrease in blood flow in the maternal internal iliac and median uterine arteries at the end of the occlusion to respectively 93.9% and 91.7% of the control values.The decrease in internal iliac and median uterine artery blood flow is attributed to an elevated fetal capillary pressure in the placenta, leading to an increased fetal placental tissue pressure which in turn compresses the maternal placental capillaries, resulting in a heightened vascular resistance and a decrease in uterine blood flow.