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Published data and our own observations were used to develop a general strategy, methodology, and approaches to the treatment of PTSD (PTSD) with separate groups of psychopharmacological agents. Features of the treatment of acute stress reactions and PTSD were identified. Differences in the efficacy of psychopharmacotherapy in these states were noted: positive results in the treatment of acute stress reactions were obtained in 90% of cases, compared with 40–60% in PTSD. Treatment recommendations for these states are presented.  相似文献   

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Neuroscience and Behavioral Physiology - The development of post-traumatic stress disorder (PTSD) in humans includes a number of symptoms, the main being intrusive memories of the trauma,...  相似文献   

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Hemolytic activity of classic and alternative complement cascades and blood concentrations of TNF-α, IL-1β, and IL-6 were measured in patients with post-traumatic stress disorder. The results attest to hyperactivity of the classic complement cascade associated with elevated content of proinflammatory cytokines and hypoactivation of the alternative complement cascade in patients with post-traumatic stress disorder in comparison with healthy individuals.  相似文献   

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The question of the nosological independence and diagnosis of post-traumatic stress disorder (PTSD) is considered from the theoretical point of view in relation to the multifactorial development of the disease. These questions are discussed using the sequelae of combat trauma (PTSD in combatants) as an example. The author’s original concepts on the sequential development of pathos and nosos, as applied to “combat” PTSD, are presented.  相似文献   

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1 前言 自然灾害中的地震,危害的不仅是人类的生命与财产,它导致的心理创伤也是巨大的.多项流行病学研究均表明,地震灾区幸存者中,约有10%会发展成为创伤后应激障碍(posttraumatic stress disorder,PTSD)[1.3],该障碍可能长年不愈[2],患者的社会职业生活等多方面功能会受到严重影响.  相似文献   

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目的 调查参加汶川地震救援的军人在震后7个月和14个月时创伤后应激障碍的检出率及心理健康状况.方法 在参与地震救援的部队中随机抽取600人,在震后7个月和14个月时采用创伤后应激障碍症状自评量表、症状自评量表进行调查.采用SPSS 13.0统计软件对第一次调查的497份有效问卷和第二次的491份有效问卷的数据进行统计分析.结果 创伤后应激障碍症状的时点检出率,7个月为37.62%,14个月为26.28%,经卡方检验两组有显著性差异(x2=14.633,P=0.000).但其中中重度症状的检出率,7个月为2.01%,14个月为1.43%,两组无显著性差异(x2=0.502,P=0.479).创伤后应激障碍症状自评量表总均分7个月时(26.70±6.47);14个月时(25.77±5.86).秩和检验差异有显著性(P=0.000).结论 对参与地震严重灾难救援的军人,应注意发现创伤后应激障碍症状尤其是有中重度症状者,并应予以个别心理治疗或药物治疗.  相似文献   

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Neuroscience and Behavioral Physiology - Objective. To study the role of traumatic brain injury (TBI) in the development of post-traumatic stress disorder (PTSD) in combat veterans. Materials and...  相似文献   

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ABSTRACT

Post-Traumatic Stress Disorder continues to be under-diagnosed among individuals with severe mental illness and substance abuse. In a convenience sample of 64 patients with severe mental disorders being treated at an urban outpatient clinic, 24% met full criteria for PTSD based upon a comprehensive assessment protocol while only 3% were diagnosed with PTSD by clinicians in the medical record (Cochran's Q = 11.267, df 1, p <.001). In contrast, there was a high rate of diagnostic agreement for psychotic and affective illnesses as well as substance abuse. More attention needs to be given to systematically assessing PTSD among severely mentally ill and dually diagnosed individuals because even highly skilled diagnosticians miss the complex presentation of symptoms with which these patients present for treatment.  相似文献   

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