Biliary endoprostheses. Plastic versus metal stents

Plastic biliary endoprostheses relieved malignant obstructive jaundice in 80% to 90% of the patients. The comfort of a completely indwelling endoprosthesis should be offered to all palliatively treated tumor patients, and external-internal catheters should be reserved for the minority of patients who return with reoccluded endoprostheses. These patients have bacterial flora that rapidly contaminates the endoprosthesis and causes encrustations and reocclusions. Thus, a second endoprosthesis also would reocclude quickly. The mechanism of reocclusion of plastic and metal endoprostheses is completely different. In plastic endoprostheses, bacterial contamination causes decomposition of the bile and subsequent encrustation. In metal endoprostheses tumor ingrowths between the struts of the stent cause reocclusion. Tumor ingrowths were observed in only 6.5% of metal prostheses with a narrow woven mesh (Wallstent), whereas prostheses with large distances between the struts (Gianturco stent) had ingrowth rates of 19% to 50%. This fact shows that tumor ingrowths can be reduced by narrowing the spaces between the metallic network, and, therefore, improvements in the design of the metal stents should reduce the occlusion rate to or below that of plastic endoprostheses, which currently have a lower encrustation rate. The major advantages of expandable metal prostheses are the relative ease and the minimal trauma of the implantation procedure. The Wallstent endoprosthesis, in particular, can be inserted through a 7-F introducer sheath and offers the chance of single-step placement. The 30-day mortality rate, therefore, was only 5%. This is significantly lower than the 30-day mortality rate after insertion of plastic prostheses (15% to 24%). Even simple external catheter drainage procedures have a higher reported 30-day mortality rate (27%). Expandable metal endoprostheses would be the most useful device if the occlusion rate could be kept under 10% in large series. Increasing the length of the endoprostheses to 10 cm in the expanded state could also improve the long-term patency rates.     

Biliary drainage: conversion of external to internal drainage

A percutaneously inserted biliary drainage catheter was converted from external to internal drainage with the use of an additional catheter advanced through the gastrostomy opening. This technique was successful in one patient with unresectable cancer of the head of the pancreas, in whom it was performed to overcome the various disadvantages of external biliary drainage.     

Biliary endoprostheses in tumors at the hepatic duct bifurcation

In 51 patients with tumors at the hepatic duct bifurcation, endoprostheses were transhepatically inserted into the bile ducts. Patients with Bismuth-3-tumors (i.e. bilateral biliary obstruction) were treated by insertion of 2 or more endoprostheses. Long-term success presumed drainage of all obstructed ducts, because cholangitis has been a common problem secondary to undrained segments. Furthermore the debris and the high viscosity of infected bile increased the risk for obstruction of the endoprostheses, which was observed in 6%. The mean time of survival was 7 months with a maximum of 26 months. In our experience endoprostheses can be used successfully in unresectable Klatskin tumours, which increases the comfort for the patients in their last months of life.     

Biliary endoprostheses. Insertion using a combined peroral-transhepatic method

The transhepatic placement of adequately sized endoprostheses for the palliation of malignant biliary obstruction is painful and requires large hepatic parenchymal tracks. Endoscopically placed biliary stents are smaller, but may not be adequate for long-term patency. The authors have used a combined peroral-transhepatic approach successfully to pull large endoprostheses through the alimentary track and into the biliary tree.     

Metallic endoprostheses for malignant tracheobronchial obstruction: Initial experience

Purpose To assess the efficacy of the Wallstent endoprosthesis in malignant tracheobronchial obstruction. Methods Seven patients with irresectable carcinoma of the bronchus were treated with nine Wallstent endoprostheses. The procedures were performed under endoscopic and fluoroscopic guidance. Wallstent endoprostheses ranging from 8–16 mm in diameter and 26–49 mm in length were deployed after balloon dilatation of the strictures. Results All stents were successfully deployed in the desired positions. There was one procedural complication and one procedure-related death. Three patients showed significant improvement in respiratory status after stenting. At a mean follow-up of 5.1 months, there has been no stent migration, fracture, or collapse. One patient had proximal tumor overgrowth that was treated with additional stent insertion. One patient died after a bout of massive hemoptysis 3 months poststenting and it was difficult to tell whether this was related to the endoprosthesis. Conclusion The use of the Wallstent endoprosthesis in malignant tracheobronchial obstruction is technically feasible.     

Percutaneous transhepatic internal drainage using polyurethane double-pigtail endoprostheses

Relief of obstructive jaundice by the percutaneous transhepatic insertion of an endoprosthesis is now a well recognised and common radiological procedure. We report the successful insertion of polyurethane double-pigtail stents (made for transpapillary endoscopic insertion) by the percutaneous transhepatic route in five patients. Our experience indicates that these stents are as effective in relieving jaundice as, and less traumatic and easier to insert than, the larger varieties in common use.     

Large-bore, long biliary endoprostheses (biliary stents) for improved drainage

Seventy-one large-bore, long biliary stents were placed in 62 patients. The 12-Fr Teflon stents with multiple side holes were made to extend from the entrance point of the biliary tree to the wall of the duodenum opposite the ampulla of Vater. The entire procedure takes one week. The techniques for placement and proper fashioning of the stents are described in detail. In one patient, the biliary tree was re-entered 15 months after the initial placement of a stent. The stent was removed percutaneously and replaced by a longer stent. The technique for removal is also described. The problems of migration and obstruction have been overcome with this technique, making this the preferred method of nonsurgical drainage of malignant obstructive jaundice.     

Biliary leaks: treatment by means of percutaneous transhepatic biliary drainage

PURPOSE: To evaluate the efficacy of percutaneous transhepatic biliary drainage in the treatment of biliary leaks. MATERIALS AND METHODS: Sixteen patients with a biliary leak involving either the common bile duct (n = 12), the biliary confluence (n = 2), or a hepaticojejunal anastomosis (n = 2) were treated by means of percutaneous transhepatic biliary drainage. The biliary leak was due to severe acute necrotizing pancreatitis in six patients, while 10 patients had postoperative leak. Percutaneous transhepatic biliary drainage was performed with a 12-F catheter, with two series of side holes positioned on both sides of the extravasation to divert bile flow away from the defect. RESULTS: In 13 patients, the biliary leak healed after drainage (mean duration, 78 days). In four of these patients, a slight residual narrowing of the bile duct was treated by means of either balloon dilation (n = 2) or balloon dilation followed by insertion of a metallic stent (n = 2). All 13 patients remained cured (mean follow-up, 38 months). Two patients with severe acute necrotizing pancreatitis died of complications unrelated to the biliary leak. Vascular complications occurred in two patients, one of whom died after surgical drainage of a subcapsular hematoma. CONCLUSION: Biliary leaks can be treated successfully by means of percutaneous transhepatic biliary drainage. The procedure is particularly useful when surgical or endoscopic management has failed.     

Displacement of occluded plastic endoprostheses into the duodenum during percutaneous biliary drainage: description of an under-reported technique

AIM: Percutaneous transhepatic biliary drainage (PTBD) is occasionally requested in patients with an occluded plastic stent in situ. We describe a technique for dislodging the stent into the duodenum during PTBD. MATERIALS AND METHODS: Twelve patients (M:F, 9:3 mean age 70 years) with plastic stents in the common bile duct (CBD) underwent PTBD. Eleven patients had malignant obstruction and one patient had Mirizzi's syndrome and a large duodenal diverticulum. PTBD was performed using right lobe access in nine patients and a left hepatic access in three patients. The level of biliary obstruction was at the lower CBD in five patients, mid-CBD in four patients and upper CBD in three patients. After standard percutaneous biliary access was established, an 8mm by 4 cm balloon catheter was gently inflated alongside the upper end of the plastic stent and advanced over a stiff guidewire, towards the duodenum, to dislodge the plastic stent. RESULTS: Plastic stents were successfully dislodged in all 11 patients with malignancy and metallic stents were deployed for palliation. In nine of 11 patients with malignant lesions the PTBD dislodgement of the plastic stent and insertion of a metallic stent was carried out as a single-step procedure. In two patients with biliary sepsis, a two-step procedure was necessary. In the patient with Mirizzi's syndrome the plastic stent could not be dislodged. No complications were observed. CONCLUSION: Plastic stents, inserted at ERCP, can be dislodged in the majority of cases at PTBD using a balloon catheter inserted alongside the failed stent without complication.     

Biliary drainage by ultrasound-guided puncture of the left hepatic duct

Percutaneous transhepatic biliary drainage under ultrasonic guidance was performed in 38 patients with obstructive jaundice due to malignancy (49 intubations). The method was used for palliation in 33 patients and for pre-operative drainage because of cholangitis in five patients. Puncture of the left lobar ducts was the method of choice (35 patients). Only in cases of poor visualisation of the left biliary ducts was right-sided drainage performed (three patients). Combined left- and right-sided drainage was necessary in nine patients. All attempts with ultrasound-guided punctures were successful. There were no complications related to the punctures. Delayed complications were cholangitis (10 patients) and bleeding (one patient). The advantages of the method compared with conventional percutaneous transhepatic biliary drainage and the advantages of the left liver lobe drainage are outlined.     

Wide-gauge bile duct endoprostheses with a port irrigation system. A new method of prolonging the drainage function]

The maintenance of adequate drainage by the bile ducts is crucial in all the endoscopic or percutaneous transhepatic procedures used today for the treatment of obstructive jaundice. We use wide-gauge polyurethane bile duct endoprostheses (F16; 5.3 mm - F20; 6.7 mm). Occlusion need not be expected to occur earlier than 4-6 months after placement. The implantation of a subcutaneous port system connected to the prosthesis by means of an F5 (1.6 mm) catheter allows not only X-ray examination of the function, but also lavage of the prosthesis and the biliary ducts. It is possible to add bile-dissolving substances, thus preventing crystallization of bile. In this way the patency of the prosthesis can be maintained for substantially longer. This also means a definite improvement in the quality of life.     

Arthroscopy in patients with knee endoprostheses

Remarkable advances have been made in knee replacement. Nevertheless, patients and surgeons still face unsolved problems following implantation of an artificial knee joint. In some cases arthroscopy may serve as a diagnostic or surgical tool. Our experience has shown that arthroscopy is helpful in diagnosing polyethylene wear, fractures of prosthetic components and loosening of the endoprosthesis. Moreover, surgical procedures can be synchronously performed, e.g. lateral release for complete or partial patellar dislocation, parapatellar denervation for retropatellar pain and resection of meniscal remnants or a synovial plica in case of interposed tissue. In contrast to knee infections, early prosthetic infections should be treated with an open procedure.     

Ultrasound-guided percutaneous drainage of meniscal cysts: preliminary clinical experience

AIM: To evaluate the efficacy of ultrasound-guided percutaneous drainage of symptomatic meniscal cysts. MATERIALS AND METHODS: Patients with lateral knee joint tenderness and swelling and confirmed meniscal cyst on magnetic resonance imaging (MRI) were consecutively enrolled for ultrasound-guided percutaneous cyst aspiration. Cysts were injected with local anaesthetic and steroid before completion of procedure. All 18 patients (all male, average age 33 years) were subsequently followed up (average time 10 months) and meniscal cyst symptoms assessed by questionnaire. Fischer's exact test used to analyse the data. RESULTS: In every case the procedure was well tolerated, and each patient indicated that they would be willing to have a repeat procedure in the future. Ten patients reported complete resolution of symptoms secondary to therapeutic cyst aspiration and had resumed participation in high-performance sport. Two patients reported a satisfactory sustained response, reporting only occasional "twinges of pain". In the remaining six patients, symptoms returned after an initial pain-free period. The pain-free period ranged from 1-8 weeks. In this study, patient outcome did not significantly correlate with any meniscal cyst characteristic. CONCLUSION: Ultrasound-guided percutaneous aspiration of meniscal cysts is a well-tolerated, simple, and safe procedure. In this small patient series, it was associated with positive early results with favourable outcomes in the mid to long-term. It should be considered in patients unsuitable for surgical debridement or as an interim therapy if surgery is delayed or postponed.