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1.
A further analysis of already published data supports the position that retardates of low ability level less frequently have retarded siblings, retarded parents, and parents low in occupational level than do retardates higher in ability level. The analysis supports the position that there are two types of retarded individuals, persons retarded as a result of gene or chromosomal anomalies, brain injury, etc., who more frequently occur in the lower-level retardate group, and persons whose retardation represents polygenic segregation, who more frequently occur in the higher-level group. 相似文献
2.
背景:局部注射具有成骨作用的辛伐他汀,可显著增加骨质疏松大鼠股骨颈及股骨髁部的骨密度及力学强度,分析局部注射辛伐他汀对股骨髁骨小梁的影响。
目的:进一步研究骨质疏松大鼠股骨内局部注射辛伐他汀对股骨髁骨小梁的影响。为将辛伐他汀应用于临床骨质疏松局部治疗提供实验基础。
方法:18只雌性SD大鼠双侧卵巢切除后3个月,制备大鼠骨质疏松模型。实验大鼠随机数字表法均分为3组,分别在实验大鼠的右侧股骨髓腔内单次注射辛伐他汀溶液5 mg、10 mg,对照组单纯注射空白载体。分别在注射后1个月处死大鼠并取材。Micro-CT扫描并定量分析骨组织形态变化。
结果与结论:给药后1个月,Micro-CT扫描结果显示,辛伐他汀治疗组的骨微结构参数如骨皮质厚度、骨小梁密度及连接率明显优于对照组。说明疏松骨骼单次注射小剂量辛伐他汀可显著促进股骨髁部骨小梁改建,改善骨骼微结构,可为强化局部、防治骨质疏松骨折的新选择进一步提供实验基础。 相似文献
3.
石斛属民族药用植物的分类及生药学研究 总被引:2,自引:0,他引:2
中药石斛早在《神农本草经》中就被列为上品,其应用历史悠久,具有养阴生津、补肾益气、润喉护嗓、活血明目、抗癌防老等功效。本文对国内外石斛属民族药用植物的分类及生药学研究进行了综述。 相似文献
4.
目的我科自2001~2005年4月对59例67膝的骨性关节炎(0A),进行关节镜检查及镜下清理术。方法镜检:膝关节骨性关节炎伴不同程度滑膜炎,滑膜皱壁粘连纤维片,关节软骨不同程度破坏。镜下清除增生滑膜,松解粘连,去除剥脱软骨、修复关节面。结果随访2月~4年,平均1.5年,术后综合评估2月~1年,优良率94%;1~2年,优良率79.2%;2年以上优良率54.8%。结论关节镜对膝关节骨性关节炎诊断能提供了比较全面的资料,并对骨性关节炎早期有良好疗效,具有创伤小、恢复快、并发症少和重复治疗等优点。 相似文献
5.
Yu. F. Isakov V. N. Fedorova V. V. Shafranov A. V. Butorina E. E. Faustova S. S. Bykovskaya N. V. Fomicheva 《Bulletin of experimental biology and medicine》1995,119(6):647-650
Assessment of the aftereffects of cryoexposure and ultrahigh-frequency cryoexposure on hemangioma tissue of various types,
cavernous and squamous, showed a higher cryogenic effect in hemangiomatous tissue preexposed to ultrahigh-frequency waves.
A quantitative criterion is proposed for assessing the efficacy of the studied methods of exposure.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 119, N
o
6, pp. 669–672, June, 1995 相似文献
6.
L. S. Eliseeva 《Bulletin of experimental biology and medicine》1993,115(4):428-431
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 115, N
o
4, pp. 401–404, April, 1993 相似文献
7.
Since the cutaneous veins of the four limbs have been used as autogenous grafts in the treatment of cardiovascular disorders, knowledge of distribution of the valves is increasingly required depending upon the use. In the gross anatomical study of distribution of valves of the trunci venae, there has been argument about locational relationships between the venous roots and the valves in the vicinity of the roots and the inter-valvular distance. However, there have been only few reports discussing detailed information about valves of the cutaneous veins of the four limbs. The authors observed patterns of distribution of the cutaneous venous valves of the four limbs of cadavers prepared for practice in anatomy. The following parts were excised from each cadaver: the cephalic, basilic, and the great saphenous veins, which originate from the acral venous network and flow into the proximal deep veins, and the venous roots communicating with these veins. An incision was made on each excised vein in the direction of the long axis under observation with a stereoscopic microscope, and the inter-valvular distance and the distance between the valve and the orifice of venous root in the vicinity of the valve were measured. The inter-valvular distance varied with type of the truncus venae, and it varied according to area even in the same truncus venae. 相似文献
8.
J Siddiqui A H Siddiqi T Itoh T Matsumoto 《Molecular and biochemical parasitology》1985,15(2):143-148
Sterols of three digenetic trematodes were isolated and characterized by infrared and 1H nuclear magnetic resonance spectroscopies, and gas-liquid chromatography and gas chromatography-mass spectrometry. Sterols identified were cholesterol, cholestanol, 24-methylcholesterol, 24-methylcholestanol, 24-ethyl-22-dehydrocholesterol, 24-ethyl-22-dehydrocholestanol, 24-ethylcholesterol and 24-ethylcholestanol. 相似文献
9.
V. N. Yakovenko 《Bulletin of experimental biology and medicine》1999,128(4):1045-1048
New electrophysiologic devices were used for the diagnostics of the state of excitable structures in the gastrointestinal
tract and correction of their motor functions. Bioelectrical and biomechanical activities form the basis of functioning of
internal organs. The mechanisms of generation of slow bioelectrical activity that are important for clinical and physiological
studies are described. One of these mechanisms is a capacitance parametric transducer converting the energy of contractions
into specific electric signals reflecting muscle functions. Another mechanism results from slow oscillations of resting potentials
of interrelated excitable cells in large neuromuscular structures of internal organs. The elaborated procedure is efficient
for preventing early postoperative paresis of the gastrointestinal tract.
Translated fromByulleten' Eksperimental'noi Biologii i Meditsiny, Vol. 128, No. 10, pp. 448–452, October, 1999 相似文献
10.
为观察链脲佐菌素(streptozotocin,STZ)双侧侧脑室注射对大鼠海马神经元突触的影响,本研究将Wistar大鼠随机分为对照组和模型组,模型组大鼠分别于第1、3d双侧侧脑室重复注射STZ3mg/kg,对照组以人工脑脊液代替STZ。21d后,取大鼠海马,免疫组织化学染色及Western blotting方法观察突触素、活性调节细胞骨架相关蛋白(activity-regulated cytoskeletal-associatedprotein,Arc)的表达;电镜观察海马CA1区神经元突触超微结构的改变。结果显示:与对照组相比,模型组大鼠海马内突触素蛋白表达显著减少,而Arc蛋白表达显著增多;模型组海马CA1区神经毡内突触结构异常,突触小泡聚集增多。以上结果提示:脑室注射STZ可影响大鼠海马突触相关蛋白的表达,引起突触超微结构异常,干扰了神经元突触信号的传导。 相似文献
11.
12.
V. P. Pashchenko 《Bulletin of experimental biology and medicine》1978,86(5):1554-1556
The viability of tissue explants of mouse kidneys, estimated quantitatively by growth in plasma-free culture, was shown to depend on several factors connected with the conditions of culture. The effect of methods of treatment of the serum, pH of the medium, and the character of distribution of the tissue explant during culture, the size of the explants, and the firmness of attachment of the tissue fragments to the substrate on this index was demonstrated.Problem Laboratory, Arkhangel'sk Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. P. Avtsyn.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 11, pp. 629–631, November, 1978. 相似文献
13.
社区精神分裂症病人照料者的生活质量研究 总被引:26,自引:2,他引:26
通过对93名精神分裂症患者的家庭照料者与100名对照者比较研究表明,照料者的躯体功能、心理功能、社会功能与经济状况都显著差于对照者。照料者的生活质量与被照料者的病期、病情严重度、整体功能、药物副作用有关;同时,照料者身份为患者母亲者其生活质量受影响最大。 相似文献
14.
目的探讨宫腔镜检查在女性不孕症患者中的应用。方法回顾性分析原发性不孕180例,继发不孕322例患者进行宫腔镜检查的结果,比较不同不孕症的差异。结果1.不孕症中输卵管阻塞为167例(33.27%),另外子宫内膜炎(24.90%)、子宫内膜息肉(10.76%)、子宫腔粘连(5.18%)、宫颈管肿物(3.98%)和先天性子宫发育异常(3.19%)也是常见原因。2.原发性不孕症中子宫内膜息肉、宫颈管肿物比例明显高于继发性不孕组,子宫内膜炎和输卵管阻塞方面继发性不孕组高于原发性不孕组。3.普通不孕组在子宫腔粘连方面明显低于试管婴儿组,在鞍状子宫等子宫先天性发育异常方面明显高于试管婴儿组。4.进行试管婴儿失败患者中原发性不孕与继发性不孕在宫腔异常分别为43.94%和36.84%,两者在子宫内膜息肉、子宫粘膜下肌瘤、宫腔粘连、宫颈管肿物、子宫内膜炎、先天性子宫发育异常等方面无显著性差异。结论宫腔镜具有创伤小,恢复快,病人无需住院的优点,在女性不孕症临床中有重要作用。 相似文献
15.
V. V. Mikhailov V. Vas Mikhailov 《Bulletin of experimental biology and medicine》1975,80(5):1288-1290
Motoneurons of the lumbosacral region of the spinal cord were studied during local botulinus paralysis. The development of paralysis of the poisoned limb was accompanied by lowering of the membrane potential, the amplitude of the antidromic action potentials and of mono- and polysynaptic EPSPs, and the input resistance, and by an increase in the critical depolarization level of the soma membrane of phasic motoneurons in the affected segments of the spinal cord. The excitability of the tonic motoneurons was substantially unchanged in the course of development of local botulism.A. A. Bogomolets Department of Pathological Physiology, Saratov Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR P. N. Veselkin.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 80, No. 11, pp. 21–24, November, 1975. 相似文献
16.
Tikhonov DB 《Neuroscience and behavioral physiology》2008,38(5):461-469
Potential-dependent sodium channels play a leading role in generating action potentials in excitable cells. Sodium channels are the site of action of a variety of modulator ligands. Despite numerous studies, the mechanisms of action of many modulators remain incompletely understood. The main reason that many important questions cannot be resolved is that there is a lack of precise data on the structures of the channels themselves. Structurally, potential-dependent sodium channels are members of the P-loop channel superfamily, which also include potassium and calcium channels and glutamate receptor channels. Crystallization of a series of potassium channels showed that it was possible to analyze the structures of different members of the superfamily using the "homologous modeling" method. The present study addresses model investigations of the actions of ligands of sodium channels, including tetrodotoxin and batrachotoxin, as well as local anesthetics. Comparison of experimental data on sodium channel ligands with x-ray analysis data allowed us to reach a new level of understanding of the mechanisms of channel modulation and to propose a series of experimentally verifiable hypotheses. 相似文献
17.
人类胚胎体外培养细菌污染12例分析 总被引:2,自引:0,他引:2
目的分析胚胎体外培养细菌污染的发生原因及预防措施。方法对中山大学附属第一医院生殖中心10年来胚胎体外培养中发生的12例细菌污染资料进行回顾分析。结果胚胎体外培养污染中,所有培养液滴有污染5例,部分液滴有污染3例,接触配子及胚胎的液滴污染有4例,培养液滴最常见的细菌为大肠埃希菌,污染的来源可能为患者生殖道、手术操作、培养环境及培养操作等。结论严格操作规程,改善培养环境,可能有效减少人类胚胎体外培养中的细菌污染。 相似文献
18.
Prasanna R Nain L Tripathi R Gupta V Chaudhary V Middha S Joshi M Ancha R Kaushik BD 《Journal of basic microbiology》2008,48(3):186-194
A set of seventy axenised and unicyanobacterial isolates belonging to the genus Anabaena were evaluated for biocidal activity against a set of phytopathogenic fungi. Among them, 35 Anabaena strains showed zone of inhibition against one or more fungi. The extracellular filtrates from 4 and 8 weeks old cultures of these Anabaena strains were further evaluated in terms of hydrolytic enzymes, proteins and IAA employing standard methods. Significant differences were also observed among the strains in terms of their FPase, chitosanase and xylanase activity, while low and relatively similar values of CMCase, cellobiase and protease activity were recorded in the strains analyzed. IAA production was also observed in all the strains. Comparative evaluation of activity of hydrolytic enzymes and antifungal activity revealed that such enzymes may contribute to the fungicidal activity of the cyanobacterial strains, besides other bioactive compounds, including IAA, which are established promising traits for biocontrol agents. This study is a first time report on the production of hydrolytic enzymes by these oxygenic photosynthetic prokaryotes, which can be potential candidates for the development of biocontrol agent(s) against selected phytopathogenic fungi. 相似文献
19.
Ya. I. Aleksevich 《Bulletin of experimental biology and medicine》1978,86(2):1071-1072
The efficacy of treatment with Diaform-3 antitoxin, given by either intracisternal or intralumbar injection in a dose of 400 i.u./kg, was compared in experiments on 100 rabbits with ascending, hematogenous, and cerebral tetanus caused by injection of 1 c.l.d. of tetanus toxin. Intracisternal injection of the antitoxin was found to be three times more effective than intralumbar (the proportion of animals cured was 31.4 and 10.2% respectively). The latter was effective only in animals with ascending tetanus, evidently because the portal of entry of the toxin into the CNS was along the peripheral nerves of the hind limbs.Central Research Laboratory, L'vov Medical Institute. (Presented by Academician of the Academy of Medical Sciences of the USSR A. M. Chernukh.) Translated from Byulleten' Éksperimental'noi Biologii i Meditsiny, Vol. 86, No. 8, pp. 212–213, August, 1978. 相似文献