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1.
Background: Little research has been conducted on functional categories in probable Alzheimer's disease (pAD). Furthermore, the findings are contradictory, since some studies report ceiling performance on tense and/or subject–verb agreement (Kaprinis & Stavrakaki, 2007 Kaprinis, S. and Stavrakaki, S. 2007. Morphological and syntactic abilities in patients with Alzheimer's disease. Brain and Language, 103: 5960. doi:10.1016/j.bandl.2007.07.044[Crossref], [Web of Science ®] [Google Scholar]; Kavé & Levy, 2003 Kavé, G. and Levy, Y. 2003. Sensitivity to gender, person and tense inflection by persons with Alzheimer's disease. Brain and Language, 87: 267277. doi:10.1016/S0093-934X(03)00106-8[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), whereas others report morphosyntactic deficits and agrammatic profiles (e.g., Altmann, Kempler, & Andersen, 2001 Altmann, L. G. P., Kempler, D. and Andersen, E. S. 2001. Speech errors in Alzheimer's disease: Reevaluating morphosyntactic preservation. Journal of Speech, Language, and Hearing Research, 44: 10691082. doi:10.1044/1092-4388(2001/085)[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: This study investigates the ability of Greek-speaking pAD individuals to produce and judge subject–verb agreement, tense, and aspect. Given pAD individuals have working memory limitations (e.g., Baddeley, 1996 Baddeley, A. 1996. Exploring the central executive. The Quarterly Journal of Experimental Psychology, 49: 528. doi:10.1080/713755608[Taylor & Francis Online], [Web of Science ®] [Google Scholar]), and given the differential processing demands of agreement, tense and aspect (e.g., Fyndanis, Varlokosta, & Tsapkini, 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]), pAD participants are expected to perform better on agreement than on tense/aspect. Based on the hypothesis that reference to the past is computationally more demanding than reference to the future/present (e.g., Bastiaanse et al., 2011 Bastiaanse, R., Bamyaci, E., Hsu, C-J., Lee, J., Yarbay Duman, T. and Thompson, C. K. 2011. Time reference in agrammatic aphasia: A cross-linguistic study. Journal of Neurolinguistics, 24: 652673. doi:10.1016/j.jneuroling.2011.07.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), a within-tense dissociation is expected to emerge. Further, on the assumption that unmarked values of functional categories are less demanding than marked values (e.g., Lapointe, 1985 Lapointe, S. 1985. A theory of verb form use in the speech of agrammatic aphasics. Brain and Language, 24: 100155. doi:10.1016/0093-934X(85)90100-2[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), the imperfective (unmarked) aspect is expected to be better preserved than the perfective (marked) aspect.

Methods & Procedures: Ten Greek-speaking mild pAD individuals and six healthy controls participated in a sentence completion task, a grammaticality judgement task, and a sentence–picture matching task. Non-parametric tests were used for analysis of results.

Outcomes & Results: PAD participants were found to be significantly more impaired in aspect compared to tense and agreement, in both production and grammaticality judgement/comprehension. Agreement was found significantly better preserved than tense in production. Similar patterns of performance have been attested in agrammatism (e.g., Fyndanis et al., 2012a Fyndanis, V., Varlokosta, S. and Tsapkini, K. 2012a. Agrammatic production: Interpretable features and selective impairment in verb inflection. Lingua, 122: 11341147. doi:10.1016/j.lingua.2012.05.004[Crossref], [Web of Science ®] [Google Scholar]). Reference to the past and reference to the future did not dissociate, whereas the imperfective aspect was found to be significantly more impaired than the perfective aspect in production.

Conclusions: PAD participants' better performance on producing agreement, compared to tense/aspect, is accounted for in terms of the differential demands these categories pose on the processing system. Agreement is computationally less demanding than tense/aspect, because the former involves processing of grammatical information only, whereas the latter involve processing and integration of grammatical and extralinguistic/conceptual information. The preponderance of tense over aspect is attributed to the subjectivity of the latter, which renders it either a category “difficult” to test, or a computationally more demanding condition. The results also show that reference to the past is as demanding as reference to the future. The hypothesis that unmarked values are easier than marked ones is not supported by our data.  相似文献   

2.
Psychometric properties of Romanian translations of the Behavior Problems Inventory-01 (BPI-01; Rojahn, Matson, Lott, Esbensen, & Smalls, 2001 Rojahn, J., Matson, J. L., Lott, D., Esbensen, A. J. and Smalls, Y. 2001. The Behavior Problems Inventory: An instrument for the assessment of self-injury, stereotyped behavior, and aggression/destruction in individuals with developmental disabilities. Journal of Autism and Developmental Disorders, 31: 577588. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and the Nisonger Child Behavior Rating Form (NCBRF; Aman, Tassé, Rojahn, & Hammer, 1996 Aman, M. G., Tassé, M. J., Rojahn, J. and Hammer, D. 1996. The Nisonger CBRF: A child behavior rating form for children with developmental disabilities. Research in Developmental Disabilities, 17: 4157. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) were explored. Respondents completed the instruments for 115 children and adolescents with intellectual disabilities. Internal consistency of both instruments' total scales was good to excellent (Cronbach's α ranging from .88 to .95) and the subscale internal consistencies were fair to excellent (with α ranging from .74 to .94). The results based on bivariate Spearman correlations and multiple regression analyses provided strong convergent and discriminant validity of both instruments. Overall, the Romanian versions of the behavior rating scales had very good reliability (internal consistencies) and convergent and discriminant validity. It is hoped that this study will be a catalyst for Romanian clinicians and researchers as well as for transcultural researchers working with Romanian individuals with intellectual disabilities to continue the exploration of the utility and psychometric quality not only of the BPI-01 and the NCBRF but also of other English language psychopathology assessment instruments.  相似文献   

3.
4.
Background: Production of passive sentences is often impaired in agrammatic aphasia and has been attributed both to an underlying structural impairment (e.g., Schwartz, Saffran, Fink, Myers, & Martin, 1994 Schwartz, M. F., Saffran, E. M., Fink, R. B., Myers, J. L. and Martin, N. 1994. Mapping therapy: A treatment program for agrammatism. Aphasiology, 8: 1954. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) and to a morphological deficit (e.g., Caplan & Hanna, 1998 Caplan, D. and Hanna, J. 1998. Sentence production by aphasic patients in a constrained task. Brain and Language, 63: 184218. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Faroqi-Shah & Thompson, 2003 Faroqi-Shah, Y. and Thompson, C. K. 2003. Effect of lexical cues on the production of active and passive sentences in Broca's and Wernicke's aphasia. Brain and Language, 85: 409426. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). However, the nature of the deficit in passive sentence production is not clear due to methodological issues present in previous studies.

Aims: This study examined active and passive sentence production in nine agrammatic aphasic speakers under conditions of structural priming using eyetracking to test whether structural impairments occur independently of morphological impairments and whether the underlying nature of error types is reflected in on-line measures, i.e., eye movements and speech onset latencies.

Methods & Procedures: Nine participants viewed and listened to a prime sentence in either active or passive voice, and then repeated it aloud. Next, a target picture appeared on the computer monitor and participants were instructed to describe it using the primed sentence structure.

Outcomes & Results: Participants made substantial errors in sentence structure, i.e., passives with role reversals (RRs) and actives-for-passives, but few errors in passive morphology. Longer gaze durations to the first-produced noun for passives with RRs as compared to correct passives were found before and during speech. For actives-for-passives, however, this pattern was found during speech, but not before speech.

Conclusions: The deficit in passive sentence production does not solely arise from a morphological deficit, rather it stems, at least in part, from a structural level impairment. The underlying nature of passives with RRs is qualitatively different from that of actives-for-passives, which cannot be clearly differentiated with off-line testing methodology.  相似文献   

5.
Background: In addition to the canonical subject-verb-object (SVO) word order, German also allows for non-canonical order (OVS), and the case-marking system supports thematic role interpretation. Previous eye-tracking studies (Kamide et al., 2003 Kamide, Y., Scheepers, C. and Altmann, G. M. 2003. Integration of syntactic and semantic information in predictive processing: Cross-linguistic evidence from German and English. Journal of Psycholinguistics Research, 32: 3754. doi: 10.1023/A:1021933015362 [Google Scholar]; Knoeferle, 2007 Knoeferle, P. 2007. “Comparing the time-course of processing initially ambiguous and unambiguous German SVO/OVS sentences in depicted events”. In Eye movement research. A window on mind and brain, Edited by: van Gompel, R., Fischer, M., Murray, W. and Hill, R. 517531. Oxford, , UK/Amsterdam: Elsevier.  [Google Scholar]) have shown that unambiguous case information in non-canonical sentences is processed incrementally. For individuals with agrammatic aphasia, comprehension of non-canonical sentences is at chance level (Burchert et al., 2003 Burchert, F., De Bleser, R. and Sonntag, K. 2003. Does morphology make the difference? Agrammatic sentence comprehension in German. Brain and Language, 87: 323342. doi: 10.1016/S0093-934X(03)00132-9[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The trace deletion hypothesis (Grodzinsky 1995 Grodzinsky, Y. 1995. A restrictive theory of agrammatic comprehension. Brain and Language, 50: 2751. doi: 10.1006/brln.1995.1039[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 2000 Grodzinsky, Y. 2000. The neurology of syntax: Language use without Broca's area. Behavioral and Brain Sciences, 23: 171. doi: 10.1017/S0140525X00002399[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) claims that this is due to structural impairments in syntactic representations, which force the individual with aphasia (IWA) to apply a guessing strategy. However, recent studies investigating online sentence processing in aphasia (Caplan et al., 2007 Caplan, D., Waters, G., DeDe, G., Michaud, J. and Reddy, A. 2007. A study of syntactic processing in aphasia I: Behavioral (psycholinguistic) aspects. Brain and Language, 101: 103150. doi: 10.1016/j.bandl.2006.06.225[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Dickey et al., 2007 Dickey, M. W., Choy, J. J. and Thompson, C. K. 2007. Real-time comprehension of Wh-movement in aphasia: Evidence from eyetracking while listening. Brain and Language, 100: 122. doi: 10.1016/j.bandl.2006.06.004[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) found that divergences exist in IWAs' sentence-processing routines depending on whether they comprehended non-canonical sentences correctly or not, pointing rather to a processing deficit explanation.

Aims: The aim of the current study was to investigate agrammatic IWAs' online and offline sentence comprehension simultaneously in order to reveal what online sentence-processing strategies they rely on and how these differ from controls' processing routines. We further asked whether IWAs' offline chance performance for non-canonical sentences does indeed result from guessing.

Methods & Procedures: We used the visual-world paradigm and measured eye movements (as an index of online sentence processing) of controls (N?=?8) and individuals with aphasia (N?=?7) during a sentence–picture matching task. Additional offline measures were accuracy and reaction times.

Outcomes & Results: While the offline accuracy results corresponded to the pattern predicted by the TDH, IWAs' eye movements revealed systematic differences depending on the response accuracy.

Conclusions: These findings constitute evidence against attributing IWAs' chance performance for non-canonical structures to mere guessing. Instead, our results support processing deficit explanations and characterise the agrammatic parser as deterministic and inefficient: it is slowed down, affected by intermittent deficiencies in performing syntactic operations, and fails to compute reanalysis even when one is detected.  相似文献   

6.
Insular degeneration has been linked to symptoms of frontotemporal dementia (FTD). Presented in this case is a patient exhibiting semantic variant primary progressive aphasia, behavioral disturbance. Upon autopsy, he was found to have severe insular atrophy. In addition, selective serotonin reuptake inhibitors were ineffective in reducing symptoms of obsessive–compulsive behaviors or emotional blunting. This case suggests that Seeley et al.'s (2007 Seeley, W. W., Allman, J. M., Carlin, D. A. and et al. 2007. Divergent social functioning in behavioral variant frontotemporal dementia and Alzheimer disease: Reciprocal networks and neuronal evolution. Alzheimer Disease & Associated Disorders, 21: S50S57. [Crossref], [PubMed], [Web of Science ®] [Google Scholar], Alzheimer Disease & Associated Disorders, 21, S50) hypothesis that von Economo neurons and fork cell-rich brain regions, particularly in the insula, are targeted in additional subtypes of FTD beyond the behavioral variant.  相似文献   

7.
Background: The syndrome of deep dysphasia is characterised by an inability to repeat pseudowords and the production of semantic errors in word repetition. Several single case studies revealed that phonological decoding might be outstandingly impaired. Recovery of deep dysphasia has only been illustrated in detail for patient NC (Martin & Saffran, 1992 Martin, N. and Saffran, E. M. 1992. A computational account of deep dysphasia: Evidence from a single case study.. Brain and Language, 43: 240474. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Dell, Schwartz, Martin, Saffran, and Gagnon (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]) tried to simulate NC's repetition performance in their connectionist lexical activation model, but it did not fit his error pattern as it assumes perfect recognition of auditory input.

Aims: In this new single case study on recovery of deep dysphasia, we intended to collect further evidence for the assumption that impaired input processing is the crucial cause of the impairment. Moreover, we aimed to explain impairment and psycholinguistic parameter effects in the connectionist semantic‐phonological model (Foygel & Dell, 2000 Foygel, D. and Dell, G. S. 2000. Models of impaired lexical access in speech production.. Journal of Memory and Language, 43: 182216. [Crossref], [Web of Science ®] [Google Scholar]) by adding a phonetic input level.

Methods & Procedures: JR's performance was repeatedly assessed in the course of recovery. Errors in naming and repetition were classified according to the taxonomy of Dell et al. (1997 Dell, G. S., Schwartz, E. M., Martin, N., Saffran, E. and Gagnon, D. A. 1997. Lexical access in aphasic and nonaphasic speakers.. Psychological Review, 104: 801838. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). JR's error patterns were simulated in the semantic‐phonological model to determine the naming disorder and to predict word repetition. In addition, we established an error modality analysis to disentangle input and output impairments in repetition. Thus, the source of each error could be subclassified as belonging to either expressive or receptive components of repetition.

Outcomes & Results: Initially there was a sharp contrast between severely impaired word and pseudoword repetition and almost unimpaired reading aloud. During recovery, performance in naming and word repetition improved a great deal, while repetition of pseudowords remained impossible. The evolvement of real word repetition was characterised by psycholinguistic parameter effects at different points in time: concreteness before length, before frequency. The connectionist model over‐predicted correct responses in word repetition as for NC. There were only few expressive repetition errors; regarding receptive errors, nonwords and null responses decreased significantly while formal errors became the dominant error type in the course of recovery.

Conclusions: The development of psycholinguistic parameter effects, dissociations in performance, the computer simulations, and results from error modality analysis as well as changes of error pattern are ample evidence for the primary decoding disorder in JR. We argue that deep dysphasia can be explained by an impairment of phonetic–phonological connections in an extended version of the connectionist one‐route model of repetition with four rather than three levels of auditory word processing. The improved real word repetition despite persisting failure on pseudowords is accounted for by an increase of both phonetic–phonological and lexical–phonological connection weights.  相似文献   

8.
Background: Anagram and Copy Treatment (ACT) and Copy and Recall Treatment (CART) have been shown to improve written communication for those with severe aphasia (Beeson, 1999 Beeson, P. M. 1999. Treating acquired writing impairment: Strengthening graphemic representations. Aphasiology, 13: 767785. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]; Beeson, Hirsch, & Rewega, 2002 Beeson, P. M., Hirsch, F. M. and Rewega, M. A. 2002. Successful single-word writing treatment: Experimental analysis of four cases. Aphasiology, 16: 473491. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]; Beeson, Rising, & Volk, 2003 Beeson, P. M., Rising, K. and Volk, J. 2003. Writing treatment for severe aphasia: Who benefits?. Journal of Speech, Language, and Hearing Research, 46: 10381060. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). More recently, the addition of a spoken repetition component to the CART programme has been suggested to enhance oral naming in moderate aphasia (Beeson & Egnor, 2006 Beeson, P. M. and Egnor, H. 2006. Combining treatment for written and spoken naming. Journal of the International Neuropsychological Society, 12: 816827. [PubMed], [Web of Science ®] [Google Scholar]; Wright, Marshall, Wilson, & Page, 2008 Wright, H. H., Marshall, R. C., Wilson, K. B. and Page, J. L. 2008. Using a written cueing hierarchy to improve verbal naming in aphasia. Aphasiology, 22: 522536. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]) and in cases with co-existing apraxia of speech (AOS) (de Riesthal, 2007 de Riesthal, M. Changes in written and spoken naming with a modified CART programme. Paper presented at the American Speech and Hearing Association. Boston, MA [Google Scholar]). No studies have investigated the use of a modified ACT and CART with spoken repetition in individuals with severe aphasia and AOS.

Aims: The purpose of the study was to examine ACT and CART modified with spoken naming repetition, using visual and auditory stimuli in the ACT sessions and home practice videos in the CART sessions, for individuals with severe aphasia.

Methods & Procedures: Three individuals, RC, AC, and MJ, with severe aphasia and coexisting AOS post left middle cerebral artery strokes participated in a 3-month programme. Participants were enrolled in modified ACT and CART with spoken repetition of the target word. For the CART programme a video was created for each word in a treatment set to facilitate repetition in the home practice programme. Probes of spoken and written performance were obtained at the onset of each session, and during baseline, treatment, and follow-up maintenance

Outcomes & Results: All participants improved in their ability to write the treatment stimuli. A 5-point scoring system (Helm-Estabrooks & Albert, 2003 Helm-Estabrooks, N. and Albert, M. L. 2003. Manual of Aphasia and Aphasia Therapy, Austin, TX: Pro-.  [Google Scholar]) was a more sensitive tool than the traditional binary scoring. None of the participants improved in the spoken naming condition with task stimuli. Mild improvement was noted in comparing pre- and post-test naming for MJ.

Conclusions: Our study supports evidence that ACT and CART may improve written naming skills in persons with severe aphasia. The inclusion of spoken repetition in the home practice CART programme may not be appropriate for cases with severe aphasia with AOS. However, further research using the technique with moderate aphasia with AOS may reveal that the technique of practice with auditory and visual stimuli is beneficial. The ease of using digital video tools with computer or augmentative devices has exciting and practical clinical application.  相似文献   

9.
ABSTRACT

We used factor analysis to examine relationships among tasks that have previously shown right hemispheric processing asymmetries. We were interested in whether processing emotion displayed by a face constitutes a distinct perceptual process from processing other facial characteristics. Interest in this topic arose after Boles [1991 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]. Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar](1 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), 59 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]91 Boles, D. B. (1991). Factor analysis and the cerebral hemispheres: Pilot study and parietal functions. Neuropsychologia, 29(1), 5991. doi: 10.1016/0028-3932(91)90094-O[Crossref], [PubMed], [Web of Science ®] [Google Scholar]] found evidence of a common process underlying face processing and then Boles [1992 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]. Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar](11 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]), 963 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]988 Boles, D. B. (1992). Factor analysis and the cerebral hemispheres: Temporal, occipital and frontal functions. Neuropsychologia, 30(11), 963988. doi: 10.1016/0028-3932(92)90049-R[Crossref], [PubMed], [Web of Science ®] [Google Scholar]] found evidence of a distinct process for the processing of the facial emotion. We used seven tasks that measured both face and non-face perception. Analysis of the asymmetries revealed measures from the five face tasks resulted in a single factor, thus failing to support the hypothesis that emotional face perception would involve a separate process from non-emotional face perception. A second factor revealed a separate process underlying enumeration, and a third factor revealed yet another process underlying line bisection. The results indicate that perceiving facial emotion results in right hemisphere processing, and faces as a whole are responsible for such processing.  相似文献   

10.
Decision-making under conditions of uncertainty was studied in 11 children with moderate to severe post-acute traumatic brain injury (TBI) using a modification of the Iowa Gambling Task (Bechara et al., 1994 Bechara, A, Damasio, AR, Damasio, H and Anderson, SW. 1994. Insensitivity to future consequences following damage to human prefrontal cortex. Cognition, 50: 715. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). We hypothesized that decision-making would be compromised in children with TBI. The results revealed that when divided into subgroups by lesion location, children with lesions in the amygdala (AM) were impaired on modified gambling task performance, but children with ventromedial (VM) lesions did not appear to be impaired on the task. These results are in contrast to studies of decision-making in adults with focal lesions of vascular etiology.  相似文献   

11.
Executive functioning influences a host of other cognitive processes and people who attend neuropsychological services are more likely to display executive dysfunction than any other cognitive deficit (Stuss & Levine, 2002 Stuss, D. and Levine, B. 2002. Adult clinical neuropsychology: Lessons from studies of the frontal lobes. Annual Review of Psychology, 53: 401433. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). Impairment in executive functioning disrupts a person's ability to effectively employ their intact areas of functioning, and undermines effective self-management of other areas of dysfunction, hampering attempts to employ compensatory strategies. Therefore, assessment of a person's executive functioning is a high priority as part of a comprehensive neurorehabilitation plan. Guided by the International Classification of Functioning, Disability, and Health model (ICF model; Peterson, 2005 Peterson, D. 2005. International Classification of Functioning, Disability and Health: An introduction for rehabilitation psychologists. Rehabilitation Psychology, 50: 105112. [Crossref], [Web of Science ®] [Google Scholar]), we suggest that an important development in the field is moving to formal assessment of executive performance in functional contexts, in addition to more traditional assessment of executive impairment. We outline a number of existing studies in this area, review current measures that can provide clinicians with useful information on these issues, and discuss how this research could be further advanced.  相似文献   

12.
Developing language treatments that not only improve trained items but also promote generalisation to untrained items is a major focus in aphasia research. This study is a replication and extension of previous work which found that training abstract words in a particular context-category promotes generalisation to concrete words but not vice versa (Kiran, Sandberg, & Abbott, 2009 Kiran, S., Sandberg, C., & Abbott, K. (2009). Treatment for lexical retrieval using abstract and concrete words in persons with aphasia: Effect of complexity. Aphasiology, 23, 835853. doi: 10.1080/02687030802588866[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Twelve persons with aphasia (five female) with varying types and degrees of severity participated in a generative naming treatment based on the Complexity Account of Treatment Efficacy (CATE; Thompson, Shapiro, Kiran, & Sobecks, 2003 Thompson, C., Shapiro, L., Kiran, S., & Sobecks, J. (2003). The role of syntactic complexity in treatment of sentence deficits in agrammatic aphasia: The Complexity Account of Treatment Efficacy (CATE). Journal of Speech, Language, and Hearing Research, 46, 591607. doi: 10.1044/1092-4388(2003/047)[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). All participants were trained to generate abstract words in a particular context-category by analysing the semantic features of the target words. Two other context-categories were used as controls. Ten of the twelve participants improved on the trained abstract words in the trained context-category. Eight of the ten participants who responded to treatment also generalised to concrete words in the same context-category. These results suggest that this treatment is both efficacious and efficient. We discuss possible mechanisms of training and generalisation effects.  相似文献   

13.
Prism Adaptation Therapy (PAT) is an intervention method in the treatment of the attention disorder neglect (Frassinetti, Angeli, Meneghello, Avanzi, & Ladavas, 2002 Frassinetti, F., Angeli, V., Meneghello, F., Avanzi, S. and Ladavas, E. 2002. Long-lasting amelioration of visuospatial neglect by prism adaptation. Brain, 125: 608623. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Rossetti et al., 1998 Rossetti, Y., Rode, G., Pisella, L., Farne, A., Li, L.Boisson, D. 1998. Prism adaptation to a rightward optical deviation rehabilitates left hemispatial neglect. Nature, 395(6698): 166169. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]). The aim of this study was to investigate whether one session of PAT using a computer-attached touchscreen would produce similar after-effects to the conventional box normally used in PAT.

In four experiments, 81 healthy subjects and 7 brain-injured patients diagnosed with neglect were subjected to a single session of PAT under two conditions: (1) using the original box, and (2) using a computer-based implementation of PAT. The session of PAT included a pre-exposure step involving pointing at 30 targets without feedback; an exposure step involving pointing at 90 targets with prism goggles and feedback; and a post-exposure step involving pointing at 60 targets, with no goggles and no feedback.

The results indicate that the expected similarity in the after-effect produced by the two conditions seems to occur only if subjects receive feedback on pointing precision by seeing their fingertip during the exposure step. Attempts to provide feedback indirectly via icons on the computer screen failed to produce the expected size in the after-effect. The findings have direct implications for computer-based treatment of visuospatial disorders in the future and computer-assisted rehabilitation in general.  相似文献   

14.
We examined the cultural validity of the College Student Reasons for Living Inventory (CSRLI) with Asian American College Students (N = 314). Although results did not completely replicate the six factor structure of the CSRLI as identified in Westefeld, Cardin, and Deaton (1992 Westefeld , J. S. , Cardin , D. , & Deaton , W. L. ( 1992 ). Development of the College Student Reasons for Living Inventory . Suicide and Life-Threatening Behavior , 22 , 442452 .[PubMed], [Web of Science ®] [Google Scholar]), partial support was found. The content of the five factors that emerged corresponded to five of the original scales. Our factor solution accounted for 50.25% of common variance and demonstrated moderate to high coefficient alphas. Validity of the CSRLI subscales was supported through significant negative relations with measures of depression and hopelessness. Furthermore, the CSRLI subscales accounted for 8% of the variance in suicidal behavior above and beyond that accounted for by the risk factors of depression and hopelessness alone.  相似文献   

15.
Deep brain stimulation (DBS) now plays an important role in the treatment of Parkinson's disease, tremor, and dystonia. DBS may also have a role in the treatment of other disorders such as obsessive-compulsive disorder, Tourette's syndrome, and depression. The neuropsychologist plays a crucial role in patient selection, follow-up, and management of intra-operative and post-operative effects (Pillon, 2002 Pillon , B. ( 2002 ). Neuropsychological assessment for management of patients with deep brain stimulation . Movement Disorders , 17 ( Suppl 3 ), S116122 .[Crossref], [PubMed] [Google Scholar]; Saint-Cyr & Trepanier, 2000 Trepanier , L. L. , Kumar , R. , Lozano , A. M. , Lang , A. E. , & Saint-Cyr , J. A. ( 2000 ). Neuropsychological outcome of GPi pallidotomy and GPi or STN deep brain stimulation in Parkinson's disease . Brain and Cognition , 42 ( 3 ), 324347 .[Crossref], [PubMed], [Web of Science ®] [Google Scholar]). There is now emerging evidence that DBS can induce mood, cognitive, and behavioral changes. These changes can have dramatic effects on patient outcome. There have been methodological problems with many of the studies of DBS on mood, cognition, and behavior. The neuropsychologist needs to be aware of these issues when following up patients, and constructing future studies. Additionally, this article will review all aspects of the DBS procedure that can result in mood, cognitive, and behavioral effects and what role(s) the neuropsychologist should play in screening and follow-up.  相似文献   

16.
Background: A number of hypotheses have been formulated to account for comprehension data in agrammatic aphasia. They explain deficits in comprehending specific structures, such as semantically reversible non-canonical sentences, for example, Trace Deletion Hypothesis (TDH, Grodzinsky, 1986 Grodzinsky, Y. 1986. Language deficit and the theory of syntax. Brain and Language, 27: 135159. doi:10.1016/0093-934X(86)90009-X[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 1990 Grodzinsky, Y. 1990. Theoretical perspectives on language deficits, Cambridge, MA: MIT Press. [Crossref] [Google Scholar], 1995 Grodzinsky, Y. 1995. A restrictive theory of agrammatic comprehension. Brain and Language, 51: 2651. doi:10.1006/brln.1995.1039[Crossref], [Web of Science ®] [Google Scholar]), or functional categories, for example, Tree Pruning Hypothesis (TPH, e.g., Friedmann, 2006 Friedmann, N. 2006. Generalizations on variations in comprehension and production: A further source of variation and a possible account. Brain and Language, 96: 151153. doi:10.1016/j.bandl.2005.06.002[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Tense Underspecification Hypothesis (TUH, Wenzlaff & Clahsen, 2004 Wenzlaff, M. and Clahsen, H. 2004. Tense and agreement in German agrammatism. Brain and Language, 89: 5768. doi:10.1016/S0093-934X(03)00298-0[Crossref], [PubMed], [Web of Science ®] [Google Scholar], 2005 Wenzlaff, M. and Clahsen, H. 2005. Finiteness and verb-second in German agrammatism. Brain and Language, 92: 3344. doi:10.1016/j.bandl.2004.05.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]); Interpretable Features’ Impairment Hypothesis (IFIH; e.g., Varlokosta et al., 2006 Varlokosta, S., Valeonti, N., Kakavoulia, M., Lazaridou, M., Economou, A. and Protopapas, A. 2006. The breakdown of functional categories in Greek aphasia: Evidence from agreement, tense, and aspect. Aphasiology, 20: 723743. doi:10.1080/02687030500513703[Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Several studies, however, report evidence contradicting these theories (e.g., Caramazza, Capasso, Capitani, & Miceli, 2005 Caramazza, A., Capasso, R., Capitani, E. and Miceli, G. 2005. Patterns of comprehension performance in agrammatic Broca's aphasia: A test of the Trace Deletion Hypothesis. Brain and Language, 94: 4353. doi:10.1016/j.bandl.2004.11.006[Crossref], [PubMed], [Web of Science ®] [Google Scholar]; Dickey, Milman, & Thompson, 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and propose new accounts to explain the comprehension deficits in agrammatic aphasia, for example, Distributed Morphology Account (DMA, Dickey et al., 2008 Dickey, M. W., Milman, L. H. and Thompson, C. K. 2008. Judgment of functional morphology in agrammatic aphasia. Journal of Neurolinguistics, 21: 3565. doi:10.1016/j.jneuroling.2007.08.001[Crossref], [PubMed], [Web of Science ®] [Google Scholar]).

Aims: Against the background above, this study investigates the ability of three Greek-speaking agrammatic individuals to comprehend a wide range of structures and functional categories: semantically reversible (canonical) active and (non-canonical) passive sentences, Complementizer Phrase, subject-verb Agreement, Tense, and Aspect.

Methods & Procedures: We administered: (a) two sentence-picture matching tasks to test comprehension of reversible active and passive sentences, and Tense; (b) a sentence grammaticality judgement task to test judgement of Tense, Aspect, and subject-verb Agreement; and (c) a picture-pointing task to test comprehension of Complementizer Phrase.

Outcomes & Results: (a) Two of the three agrammatic participants performed at chance on reversible passive sentences and above chance on active sentences. The third participant performed equally high on the two sentence types. Two participants performed at chance on Tense comprehension and one above chance. (b) The three participants were selectively or across-the-board impaired in judgement of Agreement, Tense, and Aspect. One of the two selectively affected participants had chance performance on Aspect and above chance performance on Agreement and Tense. The other one performed at chance on Aspect and Tense, and above chance on Agreement. The third participant's performance was equally poor on all three categories. (c) All three agrammatic participants performed above chance on the comprehension of Complementizer Phrase.

Conclusions: In comprehension/judgement, canonical and non-canonical sentences do not dissociate in all agrammatic speakers, while functional categories associated with the verb morphology may be compromised in the face of relatively well-preserved categories that are located higher in the syntactic hierarchy. All three agrammatic participants support the DMA, and two of them support the TDH. Instead, none of them provided support to the TPH, TUH, and IFIH.  相似文献   

17.
In contrast to research into the development of language laterality, there has been relatively little research into the development of lateralisation of emotional processing. If language lateralisation begins in childhood and is complete by puberty (Lenneberg, 1967 Lenneburg, E. H. 1967. Biological foundations of language, New York: Wiley.  [Google Scholar]) it seems reasonable that the lateralisation of the perception of emotions might also occur during this period. In this study a split field chimeric faces test using the six universal facial expressions proposed by Ekman and Friesen (1971 Ekman, P. and Friesen, W.V. 1971. Constants across cultures in the face and emotion. Journal of Personality and Social Psychology, 17: 124129. [Crossref], [PubMed], [Web of Science ®] [Google Scholar]), an emotion in the eyes test, and a situational cartoon test were administered to three groups of children aged 5/6, 7/8, and 10/11. No overall hemispace advantage was seen for the 5/6-year-old group, but by the age of 10/11 a clear left hemispace advantage (right hemisphere) was found for all six emotions. Such a pattern is comparable to a previous study that made use of adults on this task (Workman, Peters, & Taylor, 2000b Workman, L., Peters, S. and Taylor, S. 2000b. Laterality of perception processing of pro- and anti-social emotion displayed in chimeric faces. Laterality, 5: 237249. [Taylor & Francis Online], [Web of Science ®] [Google Scholar]). Moreover, a significant positive correlation between a child's ability to recognise emotions in cartoon situations and their left hemispatial advantage score was uncovered. Finally, a significant positive correlation between a child's ability to recognise emotions in the eyes of others and their left hemispatial advantage score was also uncovered. These findings are taken as evidence that there may be a relationship between the development of emotional processing in the right hemisphere and a child's emerging ability to perceive or attend to the emotional states of others. Results are discussed in relation to the child's development of a theory of mind.  相似文献   

18.
We report normative data on topographical working memory collected through the Walking Corsi Test (WalCT; Piccardi et al., 2008 Piccardi, L. , Iaria, G. , Ricci, M. , Bianchini, F. , Zompanti, L. , & Guariglia, C. (2008). Walking in the Corsi test: Which type of memory do you need? Neuroscience Letters , 432 , 127131.[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) for developing a standard administration procedure to be used in clinical and educational practice. A total of 268 typically developing Italian children aged 4–11 years performed both WalCT and Corsi Block-Tapping Test (CBT; Corsi, 1972 Corsi, P. M. (1972). Human memory and the medial temporal region of the brain . McGill University, Montreal: Unpublished doctoral dissertation. [Google Scholar]) a well-known visuo-spatial memory test. WalCT has already been validated in adults, demonstrating sensitivity in detecting topographical memory deficits even in individuals who have no other memory impairments. Our results showed that age, but not sex, affected performances. Both girls and boys had a larger span on the CBT than the WalCT. The youngest group did not differ in performing WalCT and CBT, but from 5.6 years of age children performed better on CBT than WalCT, suggesting that memory in reaching space develops before topographical memory. Only after 5 years of age do children learn to process specifically topographical stimuli, suggesting that this happens when their environmental knowledge becomes operational and they increase environmental independence. We also discuss the importance to introduce WalCT in the clinical assessment.  相似文献   

19.
Deficits in emotion recognition, a crucial aspect of social cognition, are common after serious brain injury, as are executive deficits. Since social cognition and executive function are considered to be separate constructs, our first aim was to examine the presence of emotion recognition problems in brain injury patients with dysexecutive problems. We studied 65 brain injury patients of mixed aetiology participating in a randomised controlled trial evaluating the effects of a multifaceted treatment for executive dysfunction (Spikman, Boelen, Lamberts, Brouwer, & Fasotti, 2010 Spikman, J. M., Boelen, D. H., Lamberts, K. F., Brouwer, W. H., & Fasotti, L. (2010). Effects of a multifaceted treatment program for executive dysfunction after acquired brain injury on indications of executive functioning in daily life. Journal of the International Neuropsychological Society, 16(1), 118129. doi: 10.1017/S1355617709991020[Crossref], [PubMed], [Web of Science ®] [Google Scholar]) and 84 matched controls with a test for emotion recognition. Results showed that, in patients with acquired brain injury exhibiting executive deficits, emotion recognition deficits are also present. Male patients are more impaired than female patients, irrespective of aetiology. Our second aim was to investigate whether emotion recognition problems negatively predict the results of the treatment programme. Pre-treatment emotion recognition performance significantly predicted resumption of roles in daily life (Role Resumption List; RRL) and performance on an ecologically valid test for everyday executive functioning (Executive Secretarial Task; EST) post-treatment and, in addition, interfered negatively with treatment condition. Moreover, worse pre-treatment emotion recognition skills affect the learning of compensatory strategies for executive dysfunction negatively, whereas pre-treatment dysexecutive deficits do not.  相似文献   

20.
The purpose of the present study was to examine depressive symptoms as a function of eating disorder (ED) diagnostic status and gender. A demographic questionnaire, the Beck Depression Inventory-II (BDI-II; Beck, Steer & Brown, 1996 Beck, A. T., Steer, R. A. and Brown, G. K. 1996. Manual for the Beck Depression Inventory, 2nd, San Antonio, TX: The Psychological Corporation.  [Google Scholar]), and the Questionnaire for Eating Disorder Diagnoses (Q-EDD; Mintz, O'Halloran, Mulholland & Schneider, 1997 Mintz, L. B., O'Halloran, M. S, Mulholland, A. M. and Schneider, P. A. 1997. Questionnaire for Eating Disorder Diagnoses: Reliability and validity of operationalizing DSM–IV criteria into a self-report format: Correction. Journal of Counseling Psychology, 44: 6379. [Crossref], [Web of Science ®] [Google Scholar]) were administered to a nonclinical sample of college-aged men (n = 115) and women (n = 136). Contrast tests revealed significant differences in mean BDI-II scores as a function of Q-EDD diagnostic status. This effect did not differ as a function of gender and the pattern was the same for both cognitive and somatic-affective depressive symptoms. The nature of the comorbid relationship between ED and depressive symptoms appears markedly similar across both genders.  相似文献   

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