透视下痛点阻滞与针刀治疗梨状肌综合征的临床观察

目的观察痛点阻滞与小针刀治疗梨状肌综合征的临床观察。方法将118例梨状肌综合征的患者,随机分为两组,A组为治疗组72例,在透视下采用小针刀加痛点阻滞法;B组为对照组46例,采用镇痛液局部痛点阻滞。结果A组和B组有效者分别为70例（97.2%）与34例（73.9%）,A组有效率明显高于B组（P〈0.05）;复发者A组1例（1.3%）,B组12例（26.0%）,A组明显低于B组（P〈0.05）。结论在梨状肌综合征的非手术治疗方法中,透视下痛点阻滞加小针刀治疗,疗效好,并且优于单纯痛点阻滞法。     

毫火针结合新医正骨治疗梨状肌综合征的临床研究

目的：研究毫火针结合新医正骨治疗梨状肌综合征的临床疗效,验证其安全性,探讨毫火针结合新医正骨对梨状肌综合征患者的治疗效果。方法：观察组予针刺结合新医正骨疗法,对照组予针刺结合按摩治疗梨状肌综合征,每组各60例,治疗2个疗程结束后观测其症状变化情况,根据疗效判定标准判定其临床疗效。结果：观察组治愈45例,好转12例,未愈3例,治愈率75.0％,总有效率95.0％;对照组治愈29例,好转10例,未愈21例,治愈率48.3％,总有效率65.0％。两组治愈率、总有效率比较差异有非常显著性（ P ＜0.01）,观察组疗效明显优于对照组。结论：毫火针结合新医正骨疗法治疗梨状肌综合征,疗效显著、确切,安全。     

小针刀配合中药熏洗治疗跖管综合征临床研究

目的:探讨小针刀配合中药熏洗治疗跖管综合征的临床疗效.方法:将80例跖管综合征患者随机分为两组;治疗组40例采用小针刀配合中药熏洗治疗;对照组40例进行封闭治疗,疗程结束后进行疗效分析.结果:治疗组优良率为77.5％,对照组疗效优良率为62.5％.两组比较差异有统计学意义(P＜0.05).结论:小针刀配合中药熏洗治疗跖管综合征具有简便验廉的特点,较单纯西医疗法有较强优势.     

小针刀配合中药治疗梨状肌损伤综合征疗效观察

[目的]探讨小针刀配合中药治疗梨状肌损伤综合征的疗效.[方法]将80例梨状肌损伤综合征患者随机分为研究组和对照组各40例,研究组采用小针刀配合中药治疗治疗;对照组予中医推拿治疗,疗程各为四周.[结果]两组治疗后研究组有效率97.5%,对照组有效率80%,有显著性差异(P<0.01),研究组较对照组复发率低.[结论]小针刀配合中药治疗梨状肌损伤综合征具有松解粘连,挛缩,切除疤痕,使动态平衡恢复,能有效恢复梨状肌的损伤.     

特殊方法治疗梨状肌综合征161例

目的：观察特殊方法（齐刺法和白虎摇头手法）治疗梨状肌综合征的疗效。方法：将161例梨状肌综合征患者随机分为两组,治疗组81例,采用齐刺结合白虎摇头手法治疗,对照组80例,采用常规针刺组。治疗4个疗程后进行比较,结果：治疗组总有效率96．29％,对照组76．25％,两组比较差异有非常显著性意义（P〈0．01）。治疗组在第1疗程中治愈率明显高于对照组,差异有非常显著性意义（P〈0．01）．结论：特殊方法治疗梨状肌综合征有较好的疗效。     

针刺结合超短波治疗梨状肌综合征疗效观察

目的:观察针刺结合超短波治疗梨状肌综合征的临床疗效。方法:将60例梨状肌综合征患者随机分为两组,治疗组30例,采用针刺结合超短波治疗;对照组30例单独采用超短波治疗。结果:治疗组有效率96.7%,痊愈率60.0%;对照组有效率80.0%,痊愈率30.0%。两组比较差异有统计学意义(P<0.01)。结论:针刺结合超短波治疗梨状肌综合征疗效高于单纯采用超短波治疗。     

推拿、TDP、电脑中频三联治疗梨状肌综合征75例

目的：观察推拿、TDP、电脑中频三联治疗梨状肌综合征的临床疗效。方法：将150例梨状肌综合征患者完全随机分成2组,治疗组75例,对照组75例,治疗组采用推拿、TDP、电脑中频三联治疗;对照组75例采用局部封闭、TDP、电脑中频综合治疗。观察2组治疗前后症状的改善情况。结果：治疗1个疗程后治疗组总有效率为100．0％．复发率为10．7％;对照组总有效率为96．0％,复发率为44．0％;2组总有效率、复发率分别比较,差异均有显著性意义（P〈0．05）。结论：推拿、TDP、电脑中频三联治疗梨状肌综合征有良好的疗效。     

中药离子导人法治疗腰腿痛110例疗效观察及护理体会

目的：观察中药离子导入法治疗腰腿痛的临床疗效及护理.方法：选取2009年3月～ 2010年3月期间,我科诊治的208例腰腿痛患者为研究对象,随机分为两组,以110例治疗组患者应用中药离子导人法结合中医常规综合治疗加系统护理,98例对照组患者采用中医常规综合治疗加系统护理.治疗1年后电话回访或随访所有患者,观察比较两组临床疗效.结果：110例治疗组患者52例（47.28％）临床治愈,50例（45.45％）有效,8例（7.27％）无效,总有效率达92.73％,对照组患者总有效率仅为81.63％,两组疗效差异显著（r检验P＜0.05）.结论：中药离子导入法可明显减轻患者的腰腿痛,显著提高临床疗效.     

冻结肩中药蒸气浴配合小针刀治疗临床观察

目的:观察中药蒸气浴配合小针刀治疗冻结肩86例临床疗效。方法:将86例冻结肩患者采用单盲法随机分组治疗,治疗组44例,对照组42例。治疗组采用中药蒸气浴配合小针刀治疗,对照组单纯用中药蒸气浴治疗。结果,治疗组痊愈率59.09%,总有效率为95.45%。对照组痊愈率为42.86%,总有效率为80.95%。经统计学处理两组疗效具有显著意义(P<0.05)。结论:中药蒸气浴配合小针刀治疗冻结肩疗效显著。     

中西医结合治疗小儿原发性肾病综合征23例

观察中西医结合治疗小儿原发性肾病综合征（ＩＮＳ）的临床疗效。方法：选择４６例ＩＮＳ患者，随机分为治疗组和对照组。治疗组（２３例），用强的松及中药；对照组（２３例），单纯用强的松治疗。观察临床缓解率及副反应发生率。结果：治疗组完全缓解率（７３．９％）和总缓解率（９１．３％）均明显高于对照组（６５．２％，８６．９％）。治疗组副反应率（４３．５％）明显低于对照组（７３．９％）。结论：中西医结合治疗小儿原发性肾病综合征优于单纯西医治疗。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.