浙派针灸流派灸法学术传承及技法特色

[目的] 介绍浙派针灸流派灸法的学术发展脉络及技法特色。[方法] 通过研究浙江灸法发展史料，整理各流派传承家谱，探寻基于不同学术及地域特点，具有鲜明特色的浙派针灸流派灸法学术分支。[结果] 浙派针灸流派灸法以严氏、施氏、高氏、罗氏传承脉络相对清晰完整，以化脓灸、温针灸、铺灸为特色，具有一脉相承、代有传人、法从典出、理源于经、融会贯通、守正创新的特点。[结论] 挖掘浙派针灸中的灸法分支，整理其理论来源、发展创新、技法要点、后世影响等，对扩大浙派针灸的治疗范围，推广浙江特色灸法的临床应用具有积极意义。     

壮医针灸疗法现代研究进展

壮医针灸简、便、廉、验,是古老而新兴的治病方法,临床广泛用于治疗各科疾病,极富民族特色和地方特色,是壮族人民在长期的生产、生活实践中积累和总结出的宝贵医疗经验,是壮族珍贵的文化遗产。该文对近年壮医针灸“三剑客”的临床应用及实验研究进展作一总结评价,以期进一步研究提高。     

浙北施氏针灸流派传承及其学术特色浅析

[目的] 探析浙北施氏针灸流派的传承现状及其学术特色,进一步丰富秀水医派内涵。[方法] 采用传统医史文献及现代文献整理研究方法,对施氏针灸的起源、传承及学术特色进行挖掘、分析与整理。[结果] 浙北中医文化底蕴深厚,针灸流派纷呈,名医名家众多,较有影响力的针灸流派有凌、施、严、盛、金五家,各家世代相传,且屡有创新。施氏针灸作为典型代表之一,其历史源远流长,传承活跃,内容丰富,临证中十分重视脾胃,多以健脾益胃、温运中阳为治则,且善施温针,使气得温而易行,助针刺而通调气机;重视针灸并用、针药结合,以提高临床疗效。施氏传人在传承守正的同时也在持续创新,从而充实疾病谱,丰富治疗手段,提升临床疗效。[结论] 施氏针灸在不断传承和创新的过程中,已逐步形成了浙北针灸特色的诊疗体系,可供临床学习借鉴。     

长白山通经调脏手法流派溯源与发展

长白山通经调脏手法流派起源于吉林省长白山地区,是结合针灸、推拿、药浴、敷贴等多种中医外治技术的极具中医特色的临床诊疗流派,善于使用针灸、推拿等技术诊疗疾病。一代宗师刘冠军教授结合多年临床工作经验,以＂外通经络、内调脏腑＂为主要的学术思想,形成了流派的理论基础;纪青山教授等推陈出新,完善理论,促进了流派的发展与传承;王之虹教授等拓展手法内涵,丰富诊疗体系,开展机制研究,使流派发展达到新的高度。     

浙派针灸传承历史及针灸法源流略述

[目的] 介绍浙派针灸传承历史及代表性针灸法源流。[方法] 采用传统医史文献整理研究方法，通过查阅浙派针灸历史文献，梳理了浙派针灸传承历史，并整理考订了具有代表性的针灸法及其源流。[结果] 中医学至今已发展了数千年，根据不同学术特点或地域形成了许多流派，浙派中医自古以来在中医史上就有非常重要的地位，其中浙派针灸在理论和针法灸法上均有重大贡献。从时间发展上看，从古代到现代，不断涌现出具有代表性的医家和著作，这些都没有因为历史原因而受影响。从针法灸法的源流来看，浙派针灸以浙北和浙中为发展中心，有名的医家大多集中于此，如凌氏、严氏、施氏、盛氏等。浙派各医家均有各自的特色，有的善用针法，有的善用灸法，有的擅长针药结合，这些形成了浙派针灸百花齐放的优势。[结论] 研究浙派针灸传承历史及针灸法源流对浙派针灸后世医家有很重要的教育意义，对发展浙派针灸也有积极的促进作用。     

壮医针挑疗法的临床应用研究进展

壮医针挑疗法以“三道两路”学说为基础,是壮医特色的外治法之一。该疗法因操作简便、适应证广、疗效显著,在壮族地区广泛使用。本文对近年壮医针挑疗法的临床应用研究进展进行综述,以期更好地发挥其特有优势,拓展应用空间,推动壮医的传承、发展与进步。     

中医学术流派传承的核心内容与关键要素

中医学历经千年,流派众多。流派的传承对中医药理论与实践的发展起到了良好的推动作用。在中医学术流派良性发展中,道、法、术作为传承的主要内容是保障传承质量的关键,也是保障中医学术的整体性和连续性的核心。通过对于流派传承的深入的思考和探讨,试图挖掘、归纳、概括传承的共性规律,以期发展壮大流派传承,强化中医学术特色。     

管遵惠老师子午流注学术特点介绍

管遵惠教授在继承家学和前人经验基础上,致力于针法灸法研究,开拓创新,通过对历代不同学术流派的整理研究,补充和完善了子午流注开穴方法,形成了特色鲜明的管氏针灸流派,丰富和发展了子午流注理论。本文着重介绍了管遵惠教授子午流注的学术特点。     

浙江首批“全国中医药学术流派传承工作室建设单位”建设现状及建议

[目的]梳理总结浙江何氏妇科、杭州宣氏儿科、浙江陈木扇女科以及绍派伤寒的建设现状,为浙江学术流派传承工作室建设发展提供建议。[方法]通过检索相关文献并进行文献研究,整理浙江何氏妇科、杭州宣氏儿科、浙江陈木扇女科以及绍派伤寒的传承脉络和发展历史,归纳其学术思想,探讨学术流派传承工作室的建设情况。[结果]浙江何氏妇科、杭州宣氏儿科、浙江陈木扇女科以及绍派伤寒深入挖掘本流派的学术理论,形成了独有的诊疗思想。传承模式以家族传承为主,辅以师带徒模式,建立了研究室及多个学术流派工作站。四家学术流派研究室的建立不仅对其自身的传承与创新具有重大意义,更在浙江中医药事业的发展方面起到了举足轻重的推动作用,为浙江其他医学流派工作室的建立提供了研究经验和模式。[结论]浙江学术流派传承工作室的建设需要继续深入研究中医流派学术思想,加强研究成果的临床应用,促进学术流派的发展传承。     

江南何氏世医流派(镇江支)的学术观点浅析及传承思考

在中医学发展史上,传承是中医学不断发展的重要因素。当传承体系符合历史发展规律时,中医发展就会顺利且平稳;当其发展规律违背自然现象时,则会受到各种因素的制约或干扰。江南何氏世医绵延数百年,历经宋、元、明、清至今,家族行医的历史长达800余年,目前共有30代,为中医世医绵延之最。目前其在上海地区仍有传承,但镇江地区学术传承出现断档。本文总结概括了何氏流派的相关学术思想和临床诊疗经验,探讨了如何建立有效的传承模式,提高传承质量,推动该流派的传承发展。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.