乳腺断层融合摄影+数字乳腺摄影与单纯数字乳腺摄影对乳腺癌筛查的比较研究

正目的比较断层融合+数字X线乳腺摄影与单纯数字X线乳腺摄影的筛查召回率与乳腺癌检出率。方法本研究经伦理委员会批准,获得了知情同意,并遵循HIPAA。对     

乳腺数字化断层摄影分析乳腺实质结构评估罹患乳腺癌风险:与乳腺数字化摄影比较

目的乳腺密度百分比(PD)是已被确认的罹患乳腺癌的风险因子,本研究目的是在筛查人群中评估数字化乳腺断层摄影(DBT)与数字化乳腺摄影显示的乳腺实质结构特征与PD的相关性。材料与方法本研究经专业委员会核准,受试者均签署书面知情同意书。回顾性分析2007年7月—2008年3月进行的一项经专业委员会批准的DBT筛查     

应用ROC曲线对比数字乳腺摄影与模拟乳腺摄影对病灶显示的研究

目的 对照研究数字乳腺摄影与模拟乳腺摄影在病灶显示上的差别.方法 分别将专用的TRM乳腺体模置于传统模拟和数字乳腺钼靶X线机的托盘上,采用固定65 cm的焦片距,根据乳腺体模的厚度确定适当的压力为4磅,分别获得传统模拟与数字乳腺摄影的曝光条件,并获TRM乳腺体模的传统模拟和数字照片.请5位观测者,对获得的传统模拟和数字照片上的乳腺体模影像分别在观片灯上采用"五值法"进行视读,以ROC曲线解析,并分别进行统计处理,以判断有无统计学意义.结果 在乳腺模体的传统模拟与数字照片上,视读直径为0.25～0.32 mm的钙化灶,有显著差异;视读直径为0.45～1.35 mm的肿块灶,有显著差异.结论 数字乳腺摄影的照片在显示直径为0.25～0.32 mm的钙化灶和直径为0.45～1.35 mm的肿块灶均优于传统模拟乳腺摄影照片.     

MRI乳腺非肿块样强化灶:乳腺摄影及乳腺超声对病变分类的额外价值

目的评价常规乳腺影像检查方法(乳腺摄影及超声)对判断MRI非肿块样强化灶是否为恶性病变的附加诊断价值,建立一套联合多种乳腺影像检查手段评价乳腺病变的模式。材料与方法本研究经伦理委员会批准并豁免病人的知情同意。共分析115例女性(年龄21～76岁,平均48.3     

数字乳腺三维断层摄影与MRI对致密型乳腺中乳腺癌的诊断性能对比分析

目的:对比分析数字乳腺三维断层摄影(DBT)及3.0T动态增强磁共振成像对致密乳腺中乳腺癌的诊断价值.方法:以致密型乳腺女性为研究对象,回顾性分析486例纳入研究者DB T及3.0TMRI图像的影像学特征,对比分析诊断敏感度、特异度、符合率、阳性预测值及阴性预测值.并绘制受试者操作特征(ROC)曲线,计算曲线下面积(A...     

数字乳腺X线摄影和中心组合断层投照对乳腺密度百分比的估算

目的评价临床数字乳腺X线摄影与中心组合数字乳腺断层（DBT）投照成像估算乳腺密度百分比（PD）读片者间和同一读片者内的一致性。材料与方法本研究经学术委员会通过并符合健康医疗保险要求,所有病人均签署知情同意书。对39例女性（31～80岁．平均年龄51岁）的匿名数字乳腺x线摄影和中心DBT投照行乳腺PD估算。     

乳腺磁共振成像联合乳腺数字三维断层摄影技术对乳腺良恶性病变鉴别价值

目的 探讨乳腺磁共振成像(MRI)联合乳腺数字三维断层摄影技术(DBT)对乳腺良恶性病变的鉴别价值。方法 收集自2020年4月至2022年6月于江汉大学附属医院行乳腺DBT及MRI检查,且行病理检查确诊的206例乳腺结节性病变患者的临床资料、影像资料及病理资料。绘制受试者工作特征(ROC)曲线,比较DBT、MRI、DBT+MRI诊断乳腺良恶性病变的曲线下面积(AUC)及诊断效能。结果 DBT诊断阳性预测值为80.65%,阴性预测值为86.72%。MRI诊断阳性预测值为81.25%,阴性预测值为81.64%。DBT+MRI诊断阳性预测值为83.18%,阴性预测值为98.99%。DBT+MRI诊断乳腺良恶性病变的AUC为0.911,高于DBT诊断的0.837,差异有统计学意义(Z=1.958,P<0.05)。DBT+MRI诊断乳腺良恶性病变的敏感度为98.89%,特异度为84.48%,准确度为90.78%。结论 乳腺DBT+MRI检查鉴别乳腺结节性病变良恶性效能优于单独DBT检查,与单独乳腺MRI检查诊断效能无明显差异。     

One-to-one comparison between digital spot compression view and digital breast tomosynthesis

Objective  

To assess if digital breast tomosynthesis (DBT) is at least equal to digital spot compression view (DSCV).     

Digital breast tomosynthesis: sensitivity for cancer in younger symptomatic women

Objective:Full-field digital mammography (FFDM) has limited sensitivity for cancer in younger women with denser breasts. Digital breast tomosynthesis (DBT) can reduce the risk of cancer being obscured by overlying tissue. The primary study aim was to compare the sensitivity of FFDM, DBT and FFDM-plus-DBT in women under 60 years old with clinical suspicion of breast cancer.Methods:This multicentre study recruited 446 patients from UK breast clinics. Participants underwent both standard FFDM and DBT. A blinded retrospective multireader study involving 12 readers and 300 mammograms (152 malignant and 148 benign cases) was conducted.Results:Sensitivity for cancer was 86.6% with FFDM [95% CI (85.2–88.0%)], 89.1% with DBT [95% CI (88.2–90%)], and 91.7% with FFDM+DBT [95% CI (90.7–92.6%)]. In the densest breasts, the maximum sensitivity increment with FFDM +DBT over FFDM alone was 10.3%, varying by density measurement method. Overall specificity was 81.4% with FFDM [95% CI (80.5–82.3%)], 84.6% with DBT [95% CI (83.9–85.3%)], and 79.6% with FFDM +DBT [95% CI (79.0–80.2%)]. No differences were detected in accuracy of tumour measurement in unifocal cases.Conclusions:Where available, DBT merits first-line use in the under 60 age group in symptomatic breast clinics, particularly in women known to have very dense breasts.Advances in knowledge:This study is one of very few to address the accuracy of DBT in symptomatic rather than screening patients. It quantifies the diagnostic gains of DBT in direct comparison with standard digital mammography, supporting informed decisions on appropriate use of DBT in this population.     

临床数字乳腺断层X线组合系统:剂量测量特征

目的全面描述临床数字乳腺断层成像(DBT)系统在获取乳腺摄影及断层组合影像时的放射剂量学特征dosimetric properties。材料与方法制作可压缩的脂水混合体     

Digital breast tomosynthesis: Image acquisition principles and artifacts

Digital breast tomosynthesis (DBT) is a new technology that is being used more frequently for both breast cancer screening and diagnostic purposes and its utilization is likely to continue to increase over time. The major benefit of tomosynthesis over 2D-mammography is that it allows radiologists to view breast tissue using a three-dimensional dataset and improves diagnostic accuracy by facilitating differentiation of potentially malignant lesions from overlap of normal tissue. In addition, image processing techniques allow reconstruction of two dimensional synthesized mammograms (SM) from DBT data, which eliminates the need for acquiring two dimensional full field digital mammography (FFDM) in addition to tomosynthesis and thereby reduces the radiation dose. DBT systems incorporate a moveable x-ray tube, which moves in a prescribed way over a limited angular range to obtain three-dimensional data of patients' breasts, and utilize reconstruction algorithms. The limited angular range for DBT leads to incomplete sampling of the object, and a movable x-ray tube prolongs the imaging time, both of which make DBT and SM susceptible to artifacts. Understanding the etiology of these artifacts should help radiologists in reducing the number of artifacts and in differentiating a true finding from one related to an artifact, thus potentially decreasing recall rates and false positive rates. This is becoming especially important with increased incorporation of DBT in practices around the world. The goal of this article is to review the physics principles behind DBT systems and use these principles to explain the origin of artifacts that can limit diagnostic evaluation.