想要健康地长寿,请减少含糖饮料的摄入

正要避免过多摄入含糖饮料,如苏打水、果汁、柠檬水或运动饮料,因为这些饮料可以引起许多健康问题,如体重增加、患糖尿病、心脏病或中风。但哈佛大学主导的一项发表在2019年3月《循环》的观察性研究发现了一个更为严重的后果,即含糖饮料的摄入量与早逝有关。研究人员对两项大型研究的数据进行了分析,这两项研究共纳入了11万多名调查对     

限制含糖饮料摄入可预防糖尿病

正最近一项由ANU的研究者们做出的研究结果揭示,如果坚持每天不喝含糖类的饮料,泰国每年的糖尿病发生事件将会降低数千起。这一结果来自于泰国境内从2005年到2013年之间的大规模追踪性研究,囊括了全国范围内将近40000名成年人的样本。     

含糖饮料增加糖尿病风险

一项发表于2013年1月《美国临床营养期刊》的哈佛研究发现,增甜饮料无论是含咖啡因的或是不含咖啡因的,都与发生2型糖尿病的高风险相关,而且不论男女。这是另一个在饮食停止饮用苏打和其他糖类增甜饮料的原因。     

研究显示:不吃早餐增加糖尿病风险

一项小规模的研究显示,体重过重的女性如果每天都吃早餐,有助于降低患糖尿病的风险.反之,如果不吃早餐,胰岛素的作用就会减弱,较易患糖尿病. 美国科罗拉多大学的研究人员对9名女性进行了研究,她们的平均年龄为29岁,都有体重过重或肥胖问题.研究人员让她们一天吃早餐,另一天不吃早餐,然后在午餐后为她们测量胰岛素、血糖浓度.     

胃旁路术治疗2型糖尿病的疗效分析

目的探讨胃旁路术治疗2型糖尿病的远期疗效。方法回顾性分析2006年1月至2010年12月在深圳市龙岗中心医院接受胃旁路术治疗的36例2型糖尿病患者的临床和随访资料。其中男27例,女9例;年龄17~54岁。收集术后不同时期的体重、血糖等临床数据,探讨该术式的远期疗效。结果共有36名患者被纳入到该研究中,术后2型糖尿病缓解22例,有效10例,无效4例。6例高血压得到缓解或治愈,5例高血脂恢复正常,4例糖尿病肾病消失。疾病缓解者能维持状态稳定无复发。结论胃旁路手术能降低2型糖尿病患者的血糖、血压、血脂和体重水平,安全可行,远期疗效稳定。     

胰岛素依赖型糖尿病患者的生长激素和催乳素

作者报告了胰岛素依赖型糖尿病患者血中催乳素(PRL)和生长激素(GH)与病程及失代偿状态和代偿过程中糖尿病性微血管病变明显程度之间的关系。 材料与方法:实验对象为16～50岁的胰岛素依赖型糖尿病患者,计66名(男39名,女27名),患者体重在标准体重的±10%范围内。被检者分成二组:第一组28名,病程长短不同,但无糖尿病性微     

研究:每天一罐含糖饮料患糖尿病风险增加22％

据外媒报道,本周公布的欧洲一项研究结果显示,每天喝一罐含糖的苏打饮料会导致患糖尿病的风险增加22％. 研究人员对8个欧洲国家35万人进行研究,发现每多饮用340毫升含糖饮料,与每个月只喝一罐或更少的人相比,患糖尿病的风险增加22％.     

含糖饮料与心力衰竭的关系

正这里有另一个摒除饮食中含糖饮料的另一个原因:一项2015年11月2日《心脏》杂志在线发表的一项研究表明,男性每天饮用含糖饮料与患心力衰竭风险的增加有关。心力衰竭是心脏泵出足够的血容量来满足身体需求的能力逐渐下降。研究人员从1998年到2010年对瑞典的42000名中老年男性的饮食信息进行跟踪调查。他们没有区分饮料的类型或无论饮用者是使用是蔗糖、果糖     

湖北省十堰市某地区糖尿病和糖尿病前期患病率调查

目的了解湖北省十堰市某地区糖尿病及糖尿病前期患病率情况。方法采用分层抽样方法,对2014年1月—2016年7月湖北省十堰市某地区4435名20~79岁汉族人群进行横断面调查,获取一般资料,测空腹血糖,对于空腹血糖≥6.1 mmol/L者,进一步行OGTT诊断是否为糖尿病。结果共计4435名完成调查,其中男性2620名,女性1815名。经当地人口学数据标化后,该区域内糖尿病总体患病率为11.24%(其中男性10.08%,女性12.81%),糖尿病前期总体患病率为14.98%(其中男性13.70%,女性16.73%),男女间差异有统计学意义(P<0.01)。结论十堰市郧阳区糖尿病及糖尿病前期患病率较高,应积极采取相应措施予以控制。     

含糖饮料的摄入量对健康的影响

正我们到底喝了多少含糖饮料?这里有一些令人鼓舞的消息:由哈佛大学研究人员主导于2017年11月在线发表的一项观察性研究表明,含糖饮料的摄入量在2004年至2014年间显著地下降。研究人员查看了从18,000多名儿童和青少年以及超过27,000名20岁或以上的成年人收集的数据。每隔两年,这些人都会被问到他们在过去24小时内喝过的饮料种     

Correlations between lipid levels and age, gender, glycemia, obesity, diabetes, and smoking

A low level of high-density lipoprotein cholesterol (HDL-C) is an important cardiovascular risk factor. Dietary measures and pharmacological agents are often not sufficient to reach the HDL-C target level of 40 mg/dl in patients with low baseline HDL-C. This study assesses the association between lipid levels and age, gender, body mass index (BMI), glycemia, diabetes and smoking and focuses on the parameters influencing HDL-C. In the town of Lede (Belgium) all patients aged between 45 and 64 years were invited during 1999 for a free of charge health check-up and blood test. Blood pressure, weight, length and smoking habits were recorded. Serum levels for glycemia and lipoproteins were determined. In total, 629 subjects attended for the check-up. In a logistic regression analysis age above 50 years was correlated with low HDL-C (OR = 2.27 CI = 1.10-4.68). Male gender was correlated with low HDL-C (OR = 3.85 CI = 1.77-8.43) and with high triglycerides (TG) (OR = 1.94 CI = 1.14-3.30). From the level of 90 mg/dl glycemia was correlated with low HDL-C (OR = 2.56 CI = 1.02-6.39) and high TG (OR = 2.12 CI = 1.16-4.06). Obesity was correlated with low HDL-C (OR = 2.36 CI = 1.18-4.71) and high TG (OR = 2.17 CI = 1.88-5.23). This study provides some evidence to sharpen the target levels for glycemia and BMI among patients with low HDL-C and high TG. For these patients, the target glycemia should be around 90 mg/dl and BMI around 25 kg/m2. Physical activity and diet are also important in the achievement of these target levels.     

Lipoxins,Resolvins, Protectins,Maresins, and Nitrolipids: Connecting Lipids,Inflammation, and Cardiovascular Disease Risk

Essential fatty acids and their metabolites (γ-linolenic acid [GLA], dihomo-GLA, arachidonic acid, eicosapentaenoic acid, and docosahexaenoic acid; prostaglandin E₁; prostacyclin [PGI₂]; PGI₃; lipoxins; resolvins; protectins; maresins; and nitrolipids) prevent platelet aggregation, produce vascular relaxation, inhibit neutrophil degranulation and superoxide formation, inhibit platelet activation, possess peroxisome proliferator-activated receptor-γ ligand activity, and release nitric oxide. Thus, they lower blood pressure, are anti-arrhythmic and anti-inflammatory in nature, reduce low-density lipoprotein cholesterol, ameliorate the adverse actions of homocysteine, activate telomerase, and have cytoprotective properties—actions that prevent atherosclerosis and cardiovascular disease. Because coronary heart disease (CHD) and atherosclerosis are low-grade systemic inflammatory conditions, it is likely that reduced formation of lipoxins, resolvins, protectins, maresins, and nitrolipids plays a significant role in the pathogenesis of CHD. Hence, development of stable synthetic analogues of lipoxins, resolvins, protectins, and maresins may form a new therapeutic approach to CHD and other low-grade systemic inflammatory conditions.     

Cardiovascular,diabetes, and cancer strips: evidences,mechanisms, and classifications

Objectives

To report and name firstly that there are cardiovascular disease (CVD), diabetes mellitus (DM) and cancers (CDC) strips; and disclose their mechanisms, classifications, and clinical significances.

Study design

Narrative and systematic review study and interpretive analysis.

Methods

Data sources and study selection: to collect and present related evidences on CDC strips from evidence-based, open-access, both Chinese- and English-language literatures in recent 10 years on clinical trials from PubMed according to keywords “CVD, DM and cancers” as well as authors’ extensive clinical experience with the treatment of more than fifty thousands of patients with CVD, diabetes and cancers over the past decades, and analyze their related mechanisms and categories which based on authors’ previous works. Data extraction: data were mainly extracted from 48 articles which are listed in the reference section of this review. Qualitative, quantitative and mixed data were included, narratively and systematically reviewed.

Results

With several conceptual and technical breakthrough, authors present related evidences on CDC strips, these are, CVD and DM, DM and cancers, cancers and CVD linked, respectively; And “Bad SEED” +/– “bad soil” theory or doctrine may explain this phenomenon due to “internal environmental injure, abnormal or unbalance” in human body resulting from the role of risk factors (RFs) related multi-pathways and multi-targets, which including organ & tissue (e.g., vascular-specific), cell and gene-based mechanisms. Their classifications include main strips/type B, and Branches/type A as showed by tables and figures in this article.

Conclusions

There are CDC strips and related mechanisms and classifications. CDC strips may help us to understand, prevent, and control related common non-communicable diseases (NCDs) as well as these high risk strips.