两种材料修复楔状缺损的临床疗效观察

目的对复合体Dyract AP与光固化玻璃离子水门汀3M-Vitremer修复楔状缺损的临床效果进行比较.方法55例390颗楔状缺损牙分别用复合体Dyract AP(A组)与光固化玻璃离子水门汀(Vitremer,美国3M公司)(B组)修复,于修复后1.5～2年复查.结果A组成功率94.68%,B组88.12%,两组差异有统计学意义.结论两种材料均为临床修复楔状缺损的较理想材料,Dyract AP临床效果优于3M-Vitremer.     

不同材料对楔状缺损疗效影响的分析

目的 比较Dyract AP复合体和3M-VitremerTM光固化玻璃离子水门汀两种材料修复牙体楔状缺损的临床效果.方法 便利取样法选取2009年7月至2011年6月接受楔状缺损修复治疗的89例患者的246颗楔状缺损患牙,随机法分为A、B两组。A组（121颗）采用Dyract AP复合体充填修复,B组（125颗）采用3 M-VitremerTM光固化玻璃离子水门汀充填修复,随访期为2年,评定两种材料修复成功率.结果 术后1年末,A组患牙修复成功率（91.0％）与B组（93.2％）比较,差异无统计学意义（x^2 =0.393,P＞0.05）;术后2年末,A组成功率（79.4％）显著低于B组（89.4％）,两组差异有统计学意义（x^2 =4.100,P ＜0.05）.结论 3M-VitremerTM光固化玻璃离子水门汀修复楔状缺损效果优于Dyract AP复合体。     

三种材料修复牙齿楔状缺损的疗效观察

目的比较玻璃离子水门汀、光固化复合树脂和Dyract复合体修复牙齿楔状缺损的效果.方法选择82例412颗患牙,随机分为3组,分别使用玻璃离子水门汀、光固化复合树脂和Dyract复合体修复缺损,修复1年后随访,观察疗效.结果玻璃离子水门汀组修复成功率为81.88%,光固化复合树脂组为88.32%,Dyract复合体组为95.62%.Dyract复合体组修复成功率显著高于玻璃离子水门汀组和光固化树脂组(均P＜0.05).结论 Dyract复合体是修复楔状缺损的较好材料.     

两种材料修复楔状缺损临床效果报告

目的:比较玻璃离子水门汀和Dyract AP复合树脂两种材料修复牙体楔状缺损的临床效果.方法:选择在阿克苏地区医院口腔科门诊就诊的患者50例,共331颗中等以上深度楔状缺损牙,随机分为A、B两组,A组采用玻璃离子水门汀充填修复;B组采用Dyract AP复合树脂充填修复,随访1年,评定成功率.结果:A组回访167颗患牙(23人),成功124颗,成功率74.25%;B组回访:129颗患牙(21人),成功112颗,成功率86.87%.结论:Dyract AP复合树脂修复楔状缺损优于玻璃离子水门汀.     

不同材料修复楔状缺损的临床效果观察

目的探讨3种材料修复楔状缺损的临床疗效。方法将105例患者（390颗患牙）随机分成3组,分别用GC Fuji IX GP玻璃离子水门汀（A组）、Dyract AP复合体（B组）、Z350流动复合树脂（C组）修复楔状缺损,观察比较1年后的疗效。结果 A组成功率为80.77%,B组成功率为93.85%,C组成功率为95.38%。3组成功率比较有统计学意义（χ2=18.63,P〈0.01）,其中B组与C组之间的疗效无显著性差异（P〉0.05）,A组与B、C组之间的疗效存在显著性差异（P〈0.01）。结论 Dyract AP复合体和Z350流动复合树脂是修复楔状缺损较为理想的材料。     

四种材料治疗牙体楔状缺损的疗效观察

目的：观察比较流体树脂、光固化复合树脂、Dyract复合体、玻璃离子水门汀充填治疗牙体楔状缺损的临床效果。方法：选择78例病人共184颗楔状缺损牙随机分为4纽,分别使用流体树脂（Filtek TM Z 350 Flow able Restorative,A组）、光固化复合树脂（FiltekTM Z 350 Universal Restorative,B组）、Dyract复合体（DyractAP,c组）和通用型玻璃离子（glaslonomer FX Ⅱ,D组）进行充填修复,用改良的美国公共卫生署（UnitedStatesPublicHealthService,USPHS）评价系统对患牙充填后6、12mo的效果进行临床评价。结果：在6too时通用型玻璃离子的成功率明显低于其他三组（P〈0．05）,12mo时,流体树脂和复合体的疗效均明显优于另外两组（P〈0．05）。结论：流体树脂和复合体是治疗楔状缺损较为理想的材料。     

三种材料修复楔状缺损的临床效果比较

目的比较Dyract复合体、玻璃离子水门汀、光固化复合树脂3种材料修复楔状缺损的效果。方法对93例共360颗楔状缺损的患牙随机分成3组,各修复120颗。结果经过18个月的追踪观察,Dyract组成功率达98.33%,玻璃离子组成功率为96.67%,复合树脂组成功率为90.83%。结论Dyract复合体粘结性强,对牙髓刺激小,其疗效优于玻璃离子与复合树脂,是修复楔状缺损较为理想的材料。     

三种充填材料修复楔状缺损的临床效果

目的 选择比较理想的修复楔状缺损的材料.方法 160例患者的510颗患牙随机分为3级组,分别用FX-Ⅱ型玻璃离子,Spectum光固化复合树脂和Dyract AP复合体修复楔状缺损,修复1、3年复查,观察临床疗效.结果 修复后1、3年成功率分别为:FX-Ⅱ玻璃离子组83.77%、73.48%;Spectum光固化复合树脂91.93%、77.30%;Dyract Ap复合体93.13%、91.11%;术后1年Dgyact复合体组、Spectum光固化复合树脂,成功率高于FX-Ⅱ玻璃离子组,3年Dgyact复合体组成功率高于Spectum光固化复合树脂、FX-Ⅱ玻璃离子组(P＜0.05).结论 Dgyact Ap复合体修复楔状缺损较于Spectum光固化复合树脂、FX-Ⅱ玻璃离子组临床效果较好.     

两种充填材料修复楔状缺损的临床比较

目的比较Dyract复合体与富士IX玻璃离子水门汀修复楔状缺损的效果。方法将65例405颗楔状缺损患牙随机分成2组,观察组用Dyract复合体修复210颗牙,对照组用富士IX玻璃离子水门汀修复195颗牙。结果经过1年-2年追踪观察,Dyract组1年成功率达90.95%,2年成功率达88.10%;富士IX玻璃离子组1年成功率为72.82%,2年成功率达69.23%,2组比较有显著性差异（P〈0.05）。结论 Dyract复合体是修复楔状缺损较为理想的材料。     

3种材料修复牙体楔状缺损的临床疗效对比

目的:观察比较玻璃离子和光固化树脂及复合体3种材料修复牙体楔状缺损的治疗效果。方法:选择60例386颗患牙,随机分为3组,即玻璃离子粘固剂修复组、光固化树脂修复组、复合体修复组,进行对比观察。结果:2年疗效光固化树脂修复组总成功率60.34%,玻璃离子粘固剂修复组总成功率75.93%,Dyract复合体修复组成功率为91.36%。结论:Dyract复合体修复楔状缺损临床疗效明显优于玻璃离子粘固剂及光固化树脂。     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.     

Scientific principles and rigorous processes should be followed in developing clinical guidelines for therapeutic interventions of integrative medicine

A clinical guideline for the therapeutic interventions of integrative medicine may be defined as a written document which states a series of recommendations on therapeutic interventions of integrative medicine for a special disease or condition. The guideline may provide assistance to medical professionals in making clinical decisions aimed at improving the clinical outcome of patients and reducing the costs of medical care（~＇4~. Recommendations issued by a guideline should be based on the best available evidence in both Western and Chinese medicine. For fulfilling this purpose, the development of clinical guidelines for therapeutic interventions in the field of integrative medicine should follow scientific principles and undergo a rigorous processes.