家庭内感染麻风1例

<正>1临床资料患者女,35岁。腹部出现巴掌大淡红斑2年3个月,伴轻度瘙痒。2个月前右手腕和右大腿出现2处类似皮损,并逐渐增大。当地医院以"神经性皮炎"治疗1月﹙药名不详﹚,无效。遂至本院就诊。皮肤科情况:肚脐上方有一15.0cm×10.0cm大淡红斑,界清,伴轻度瘙痒,右手腕部见一5.0cm×5.0cm环形淡红斑,边缘隆起,内外缘界清;右大腿内侧出现5.0cm×8.0cm大的淡红斑,均有轻度瘙痒感。神经干检查示:右尺神经粗大,无压痛,运动功能正常,余系统检查未见异常。     

麻风的家庭内感染

作为麻风控制方案的一部分,作者于1962～1970年期间对Gudiyatham Taluk(南印度的一个有40万人口的行政单位)的居民做了两次普查并对已确诊的麻风病人进行了随访研究。对有麻风病人的5088户家庭(其中仅有1个病例的单发户占87％)中的22652名接触者进行了临床检查以确定有无麻风,受检率为97.3％。确定了家庭内麻风接触者中所发生的新病例数——继发性发病率(Secondary attack rates),并对与原发病例和接触者有关的特点进行了研究。继发性发病率的定义为     

家庭内传染麻风29例

张家港市至1994年底累计发现麻风175例,其中29例(16.6％)为家庭内传染。29例中男23例,女6例;多菌型12例,少菌型17例;发病年龄9个月～83岁,平均21.78岁;年龄3～83岁;平均24.81岁。传染源为父母者19例,兄弟姐妹者6例,夫妻者2例,子女者1例,外祖母1例。传染源共23     

283户麻风家庭内感染情况调查分析

２８３户麻风家庭内感染情况调查分析皋官蔚（江苏省东台市皮肤病防治院，２２４２００）我市１９７３～１９９３年期间共新发生麻风病２８３户，其中多菌型９１户，少菌型１９２户，共发生麻风３２１例。麻风多发户３４户占麻风总户数的１２．０％。在１２７４名家属中有...     

56例麻风家庭内传染情况

1970年以来在麻风病人的家属中发现56例发病者,占同期发现病人数的5.9％,其中男38例,女18例,MB13例,PB 43例;年龄7～76岁,平均27.23岁,15岁以下的17例(30.45),16～30岁20例(35.7％),31～50岁13例     

麻风家庭内发病89例的统计分析

麻风家庭内发病８９例的统计分析傅鸿坤，邓显谷（云南砚山县皮肤病防治站，６６３１００）砚山县１９８８～９２年５年间新登记病人１７４例，其中家内发病８９例，占５１．１５％；８９例中男６７例，女２２例；多菌型４７例，少菌型４２例。家内发现新病人过半，现报告...     

麻风的家庭内聚集性检验

疾病的家庭内聚集性检验,一般多用二项分布拟合法。笔者曾用该法处理了此间的一组麻风流行病学资料,结果与二项分布的概率没有显著差别。为了使结论更严谨更科学,笔者改用Dottroff介绍的G检验法对同一资料作了处理,结果能较客观地反映麻风的家庭内聚集性。一、资料见附表。     

家庭内麻风接触者在传播麻风中的作用

本研究采用病例对照模型研究Asanambut地区家庭内麻风接触者在传播麻风中的作用.该地区自1971年以来,已进行了麻风防治工作,麻风发生率为38.66/1000.作者选择1983年7月～1984年12月,在Asanambut调查、教育、治疗(SET)联合部发现的病人作为研究对象,其中5例因死亡或     

贵州省306例新发麻风家庭内感染者调查分析

回顾性分析2011-2015年942例新发麻风患者的临床资料,显示家庭内接触感染发病306例(32.48%),其中男217例,女89例,年龄7~89岁,平均年龄34.58岁,15岁以下31例(10.13%);多菌型242例(79.08%),少菌型64例(20.92%);诊断延迟期6天~40.80年,平均为2.60年;I级畸残53例,II级畸残92例;大多数传染源为血缘亲属(276例,90.20%),由父母感染者占49.67%(152例)。     

麻风患者家庭内发病的调查

经反复调查核实,至1986年底,日照市累计发现病人1508例,分布于556个自然村、1377户中。病人家庭内又有新发病者108户,续发患者131例,其中男97、女34;年龄5～75岁,平均23.22岁;L32、T95、B3、I1。有病人的1377户中只有一个病人者1269户,家内有续发病例者108户(7.84％);病人家属5149人中,发病者131例,患病率为25.45‰。一户有2例病人者91户,3例者13户,4例及5例者各2户。家中原发病     

羊痘二例

报道2例人感染羊痘，通过临床及实验室经荧光PCR检测确诊。例1，女，55岁。有病羊接触史，左手无名指出现黄豆大感染性肉芽肿改变1个月，外阴多发疣状增生20天。例2，女，46岁。左手两个手指有红色结节伴触痛半月，发病前有病羊接触史。两例患者经PCR检测羊痘病毒DNA均阳性，经抗病毒及冷冻治疗后皮肤逐渐恢复正常。     

Dermatomyofibroma: report of two cases

Dermatomyofibroma is a recently described, benign acquired cutaneous proliferation of fibroblasts and myofibroblasts. We report 2 additional cases, both in young women. The lesions measured 0.5 and 1.0 cm and were located on the breast and upper back. Follow-up at 8 months and 3 years revealed no evidence of recurrence. Both lesions exhibited a uniform population of spindle cells forming intersecting long fascicles with a tendency to horizontal orientation in the reticular dermis. Cytologic atypia was absent and mitotic figures were minimal or absent. Collagen was present as thin fibers separating individual cells and as thicker bundles between the fascicles. A fine reticulin network surrounded the spindle cells. Elastic Fibers were mostly preserved and appeared thicker or even increased in number. The spindle cells were immunoreactive for vimentin and muscle actin and negative for desmin, S-100 protein, factor XIIIa, and CD34. Electron microscopic studies confirmed the presence of myofibroblasts. The differential diagnosis was made with cellular and fibrous dermatofibroma, piloleiomyoma, hyperlrophic scar, and dermatofibrosarconia protuberans, both classic and plaque type. The data presented supports the histologic distinction of dermatomyofibroma from other fibroblastic proliferations of the skin.     

Panfolliculoma: report of two cases

Panfolliculoma is a distinctive and unusual benign follicular neoplasm. It shows differentiation towards all components of the hair follicle, including the upper and the lower segments. We report two cases of this rare disease. The first patient presented with a painful nodule on the scalp and the second patient had an asymptomatic skin-colored nodule on his left eyebrow. Histopathologic examination of both cases revealed lobular proliferation of solid-cystic follicular structures. The cystic structures contain laminated keratin, indicating infundibular differentiation. The solid tumor part was composed of basaloid germinative cells, matricial cells, and cells with trichohyalin granules, representing inner root sheath differentiation. The range of differentiations was highlighted using immunohistochemical stains, including labeling of cytokeratin 1, 5, 10, 14 (using 34bE12), cytokeratin 5/6, CD34 (outer root sheath), and Ber-EP4 (lower segment of hair follicle). Panfolliculoma should not be confused with trichofolliculoma or trichoblastoma.     

Retronychia: report of two cases

Retronychia is an incomplete form of nail shedding that leads to embedding of the nail into the proximal nail fold and subsequent inflammation. Patients present with persistent paronychia in the setting of disrupted nail growth. Other nail changes may be present. Simple avulsion is curative, and unlike other forms of ingrown nails, it does not tend to recur. We report 2 cases of retronychia that were associated with distal onycholysis and subungual hematoma, respectively. Both were successfully treated with nail avulsion.     

反向性银屑病二例

<正>临床资料例1,患者,女,48岁。7年前,患者头皮出现红色丘疹、斑块伴银白色鳞屑,轻度瘙痒,院外诊断为"银屑病",给予药物治疗(具体药物不详)后皮损消退,此后皮疹反复出现。3个月前,患者头皮再次出现大量银白色鳞屑,并出现双侧腋下、会阴部境界清楚的红斑。患者无高血压、糖尿病、心脏病等病史,家族中无类似疾病史。查体:一般情况好,系统检查未见明显异常。皮肤科情况:头皮大量银白色鳞屑,可见束状发。双侧腋下、会阴部境界清楚的红斑,未见明显鳞屑(图     

疱疹样天疱疮二例

<正>临床资料病例1,女,71岁,农民。主因背部及四肢红斑、丘疹、斑块伴瘙痒20天,2019年3月7日于我院就诊。患者20天前口服汤药后双膝部出现散在粟粒大红色丘疹,伴瘙痒,未在意。13天前自觉瘙痒感加重后于当地诊所就诊,未明确诊断,予口服药物治疗,具体成分和剂量不详,用药后皮疹面积扩大,于双下肢及背部出现红斑、丘疹及斑块,遂于我院就诊。来诊时患者瘙痒感明显,皮损处可见明显抓痕及血痂,未见明显水疱。体格检查:系统查体未见异常。皮肤科查体     

色素性痒疹2例

报告2例色素性痒疹.例1为女性,26岁.颈部、胸腹部、背部出现淡红色丘疹伴剧烈瘙痒1年.皮损反复发作,消退后遗留网状色素沉着斑.例2为男性,17岁.颈、胸、背部出现红色丘疹及网状色素沉着伴剧烈瘙痒半年,皮损呈风团样,反复发作.2例患者皮损组织病理检查结果均显示非特异性苔藓样皮炎改变.经口服米诺环素200mg/d治疗3周后,2例患者红色丘疹均完全消退,瘙痒消失,原皮损部位遗留网状色素沉着斑,随访2个月无复发.     

浅表型纤维瘤病二例

病例1,女,73岁。因双手掌结节伴活动受限7月余来我院就诊。患者7月前无明显诱因双手掌出现皮下肿物,无明显自觉症状。肿物逐渐增大,双手手指不能伸直,以小指无名指为重,功能受限。患者有肝癌病史4年,治疗情况不详。皮肤科检查：双手掌多发深在质硬结节,皮色,大小约0.6 cm×0.5 cm。表面光滑、不活动,与局部皮肤有粘连。掌部皮肤褶皱,手指屈曲,活动受限。左手拇指皮下组织萎缩。     

隆突性皮肤纤维肉瘤二例

例1男,38岁。枕后肿块12年,质硬,表面皮肤光滑。例2女,54岁。右上臂紫红色肿块11年,质中等,表面毛细血管扩张。组织病理示:真皮及皮下组织大量组织细胞和胶原纤维呈蓆纹状、轮辐状、漩涡状排列。免疫组化:CD34+,Ki67+。两例均诊断为隆突性皮肤纤维肉瘤。     

Anogenital granulomatosis: report of two cases

Anogenital granulomatosis (AGG) is a rare chronic inflammatory disorder of unknown aetiology. It presents clinically with swelling of the genital or anoperineal area, with histopathological findings of noncaseating giant cell granulomas. Some cases of AGG are associated with underlying systemic disease, mainly Crohn disease. We report two patients with AGG. The first was a young man with ulcerative colitiis treated with infliximab, which also alleviated the developing symptoms of AGG. The second was a young woman who was otherwise healthy. After the introduction of complex decongestive therapy, the oedema was considerably reduced in both patients.