神经导航辅助下经鼻蝶入路神经内镜切除垂体腺瘤22例临床分析

目的探讨神经导航辅助下经鼻蝶入路微创内镜切除垂体腺瘤临床应用价值。方法回顾性分析该院2013年1月-2015年1月收治垂体腺瘤患者共22例,均在神经导航辅助下经鼻蝶入路行微创内镜切除,术中对肿瘤组织及周围重要解剖结构进行准确定位,确定病灶切除程度。结果所有病例均成功完成手术,其中肿瘤全切除19例,次全切除3例;术后出现一过性尿崩症7例,2例发生短暂性脑脊液漏,无颅内感染及死亡病例。结论神经导航辅助下经鼻蝶入路微创内镜切除垂体腺瘤可准确定位肿瘤组织,实时观察病灶大小及周围重要解剖结构;通过神经导航与微创内镜联合运用可在最大范围内对肿瘤进行安全切除,明显减少术中创伤和术后并发症。     

神经导航在经蝶垂体瘤手术中的应用

目的 探讨神经导航在经蝶垂体瘤术中的应用价值。方法 应用神经导航技术经蝶切除26例垂体腺瘤。术前行三维重建，确定手术入路，术中实时导航，监测肿瘤切除程度。结果 26例垂体瘤在神经导航引导下均能精确定位，肿瘤全切18例，次全切8例；术后7例出现一过性尿量增多，无脑脊液漏和颅内感染，无手术死亡。结论 经蝶垂体瘤手术中，神经导航可提供实时三维定位，有助于提高肿瘤切除率，减少手术并发症。     

神经导航辅助神经内镜下经蝶垂体腺瘤切除术（附21例报告）

目的：评价神经导航辅助神经内镜下在经鼻蝶垂体腺瘤切除术中的应用。方法回顾性分析21例垂体腺瘤在神经导航辅助神经内镜下经鼻蝶入路手术患者的临床资料,包括导航的定位、肿瘤切除程度等。结果21例患者中,术中导航精确,神经导航注册误差为0.4～1.9 mm,平均0.9 mm,肿瘤全切16例,次全切除5例,所有视力、视野缺损患者均有改善。8例一过性尿崩症痊愈出院,1例脑脊液鼻漏经过改变体位治愈,1例垂体功能低下需激素替代治疗。结论神经导航辅助神经内镜下在经鼻蝶垂体腺瘤手术中能够准确、实时定位肿瘤与周围重要解剖结构,可最大范围地切除肿瘤,并能减少术中损伤和术后并发症。     

立体定位经鼻内窥镜蝶鞍部肿瘤切除的手术护理配合

目的 探讨立体定位经鼻内窥镜蝶鞍部肿瘤切除手术的护理配合.方法 总结2004年5月～2005年3月对6例蝶鞍部肿瘤病人实施立体定位经鼻内窥镜蝶胺部肿瘤切除的密切配合.结果 6例病人均完整切除肿瘤,术中出血量少,术程缩短.结论 做好围手术期护理,熟悉立体定位及鼻内窥镜仪器的操作配合,为手术顺利进行提供可靠的保证.     

立体定位经鼻内窥镜蝶鞍部肿瘤切除的手术护理配合

目的探讨立体定位经鼻内窥镜蝶鞍部肿瘤切除手术的护理配合。方法总结2004年5月~2005年3月对6例蝶鞍部肿瘤病人实施立体定位经鼻内窥镜蝶胺部肿瘤切除的密切配合。结果6例病人均完整切除肿瘤,术中出血量少,术程缩短。结论做好围手术期护理,熟悉立体定位及鼻内窥镜仪器的操作配合,为手术顺利进行提供可靠的保证。     

2例McCune-Albright综合征合并生长激素腺瘤患者的围手术期护理

总结了2例McCune-Albright综合征合并生长激素腺瘤患者行经蝶垂体腺瘤切除术的护理方法.患者均行神经导航辅助下经蝶窦入路垂体腺瘤切除术.术前重视患者的心理变化.为手术做好动态MRI等相关检查及治疗.术后严密观察患者有无继发性蝶鞍区出血、脑脊液漏、水电解质紊乱、垂体功能低下等并发症.患者手术顺利,术后恢复良好.患者术后生长激素水平均有明显下降,这内分泌学治愈.     

内窥镜辅助下经蝶窦行垂体腺瘤切除术19例临床分析

【目的】探讨内窥镜辅助下经蝶窦行垂体腺瘤切除术的手术方法。【方法】分析内窥镜辅助下经蝶窦行垂体腺瘤手术19例的临床特征及疗效。【结果]19例患者术前CT、MRI显示,其中微腺瘤5例,大腺瘤7例,巨大腺瘤7例。内窥镜辅助下经蝶窦行垂体腺瘤切除术全切除肿瘤14例,大部切除5例．术后随访1～3年,主要临床症状均有不同程度改善。【结论】内窥镜辅助下经蝶窦行垂体腺瘤手术方法具有微创、简便,并发症少的优点,是垂体瘤手术治疗的较佳手段。     

影像导航在鼻内镜下眼眶手术的临床研究

目的 探讨影像导航技术在鼻内镜眼眶微创手术中的应用.方法 回顾性分析7例患者,其中视神经损伤3例;眶内球后异物3例;球后肿瘤1例(血管瘤).所有病例均采用Brain Lab影像导航系统及鼻内镜实施手术.结果 影像导航术前准备时间(包括配准、头架定位、常规器械注册等)10～20min,平均15 min.手术区域影像标志与实体解剖标志间的误差≤1.3 mm.影像导航可准确定位视神经等解剖标志,无手术并发症发生.结论 影像导航系统可以帮助术者在术中定位眼眶内重要的解剖结构,并可使手术视野扩展到内镜之外,使术者在术野中进行手术操作的同时,能顾及术野周围的重要结构,特别是在复杂的手术中,可提高手术的精确性和安全性.     

3D-Slicer软件在神经内镜经鼻蝶入路垂体腺瘤手术中的应用

目的 探讨3D-Slicer软件辅助神经内镜经鼻蝶入路垂体腺瘤手术的疗效与价值。方法 28例垂体腺瘤患者行头颅CT和头颅MRI检查,将影像数据输入3D-Slicer软件,对蝶窦、鞍区骨性结构、垂体腺瘤及颈内动脉、视神经结构进行三维重建,并行术前规划,判断神经血管和肿瘤的空间关系,模拟磨除鞍底的过程,将重建图像与术中图像进行比较,评价两者吻合程度,记录术后并发症和疗效。结果 所有患者的三维重建图像中,蝶窦、鞍区骨性结构、垂体腺瘤及神经血管均可清晰显示,与术中内镜下实际图像高度匹配,能准确识别重要结构,并规划出鞍底骨窗的合适范围。所有患者手术过程顺利,术后均未发生严重并发症。结论 3D-Slicer软件运用于神经内镜下经鼻蝶入路垂体腺瘤手术,有助于术前明确显示蝶窦、蝶鞍、肿瘤与神经血管的空间关系,可帮助提高手术安全性与手术效率。     

内镜下经鼻蝶入路垂体腺瘤切除术的护理配合

[目的]探讨内镜下经鼻蝶入路垂体腺瘤切除术的术中护理配合。[方法]2016年1月—2017年6月对13例内镜下经鼻蝶入路垂体腺瘤切除术进行护理配合,总结术中护理配合。[结果]本组病人垂体腺瘤全切除10例,次全切除3例,手术时间60 min~105min,术中无大出血及脑脊液漏,术后并发脑脊液漏1例,经保守治疗1周后恢复,术后发生短暂性尿崩2例,使用药物治疗后恢复,术前有轻微尿崩者术后未见明显加重,无死亡病例。[结论]加强内镜下经鼻蝶入路垂体腺瘤切除术的护理配合是手术成功的保证。     

内镜下经单鼻孔蝶窦入路切除垂体腺瘤的临床研究

目的 探讨神经内镜下经单鼻孔蝶窦入路在垂体腺瘤切除术中的临床应用.方法 回顾性分析47例内镜下经单鼻孔蝶窦入路治疗垂体腺瘤患者的临床资料及手术方法,观察其疗效及并发症.结果 肿瘤全切除39例(82.9％),次全切除6例(12.8％),部分切除2例(4.3％).术后并发症有暂时性尿崩症11例,脑脊液鼻漏3例,术后鼻腔出血2例,颅内感染1例.无死亡病例.术后随访6～24个月,临床症状多有不同程度改善;术后内分泌学复查,25例激素水平降至正常,无肿瘤复发.结论 内镜下经单鼻孔蝶窦入路切除垂体腺瘤具有创伤小、并发症少、患者恢复快等优点,是治疗垂体腺瘤的一种安全、有效的方法.     

神经内镜控制下经鼻-经蝶手术入路切除垂体腺瘤

目的 探讨神经内镜控制下单鼻孔经蝶手术入路切除垂体瘤的适应证、手术方法、手术技巧及其优点。方法 经内镜控制下单鼻孔经蝶手术入路手术治疗垂体瘤患者9例。结果 肿瘤全切7例，次全切2例。手术效果良好。并发症2例;脑脊液漏及颅内感染1例，尿崩、高热、意识障碍1例。无死亡。结论 神经内镜控制下单鼻孔经蝶手术入路切除垂体瘤较传统手术方法具有微创、照明良好、视野开阔、并发症较少等优点，是垂体瘤手术治疗的发展方向。     

Comparision of stress response severity during intravenous, inhalation and combined anesthesia (inhalation plus local) for pituitary transsphenoidal adenomectomy

Transsphenoidal pituitary surgery is usually accompanied by severe hemodynamic stress response which is hardly treated with fentanyl. The main goal of the study is to compare anesthetic methods for endonasal endoscopic transsphenoidal pituitary adenomectomy and single out the most effective way of reducing or preventing the stress reaction. 65 patients underwent endonasal endoscopic transsphenoidal pituitary adenomectomy. In all the patients general an- esthesia was induced with propofol. Analgesia was provided by phetanyl boluses. The patients were divided into three groups. In the first group of patients TIVA with propofol-TCI was used. In the second group of patients anesthesia was maintained by N20 plus sevoflurane. The third group of patients received an additional bilateral endoscopic mucosal 2% lidocain 5 ml infiltration of the pterygopalatine nerve branches zone. Pipecuronium was used for neuromuscular blockade. The simultaneous HR, ABP and metabolism increase were qualified as stress response. In the first and second groups of patients the maximum stress response was recorded on the stage of mucosal coagulation and on the opening of the blades of bivalve nasal speculum. No major difference in stress response severity was noted in these groups. In the third group stress response was significantly lower. According of the results of the study bilateral endoscopic mucosal lidocaine infiltration of the pterygopalatine nerve branches zone for anesthetic management of endonasal endoscopic transsphenoidal pituitary adenomectomy can be recommended.     

神经导航辅助下经鼻蝶入路垂体瘤切除术及手术配合

目的探讨神经导航在经鼻蝶垂体瘤切除术中的应用及护理配合技术。方法应用导航技术经鼻蝶窦切除49例垂体腺瘤。术前行三维重建,确定手术入路,术中实时导航,监测肿瘤切除程度。做好患者心理护理,掌握神经导航仪的操作方法,备齐术中所需器械、物品和药物,熟悉手术配合过程,术中严格无菌操作。结果49例患者全切38例,次全切11例,术后原有症状均有明显改善,无严重并发症发生,均痊愈出院。结论神经导航辅助下经鼻蝶垂体瘤切除术是一种定位准、损伤小、反应轻、疗效好的微创手术,高质量的手术配合是手术成功的重要保证。     

鼻内镜下经鼻蝶入路海绵窦解剖学研究

目的 通过鼻内镜下经鼻蝶入路海绵窦解剖学研究,为临床治疗海绵窦区病变提供解剖学基础.方法 在12例成人尸头上进行,在鼻内镜下经鼻蝶入路进入海绵窦,观察窦内重要血管、神经的走行,并从颅内切开海绵窦,测量神经血管在窦内的长度、外径及与鞍底中线间的距离.结果 在鼻内镜下可顺利进入海绵窦,清楚显露海绵窦内、外壁、颈内动脉、动眼神经、滑车神经、外展神经及眼神经,并对其进行全程游离.结论 鼻内镜下经鼻蝶入路进入海绵窦,操作简便,创伤小,可清楚暴露海绵窭内部结构,可用于临床上海绵窦病变的治疗.     

Endoscopic drill-assisted dacryocystorhinostomy

Summary

With the introduction of endoscopes for endonasal surgery, there have been an increasing number of endonasal dacryocystorhinostomies (DCR) performed. The advantages of the endonasal approach include the avoidance of an external facial scar and reduced risk of damage to the medial canthal ligament. We described our experience with the use of the Hall Osteon drill for endoscopic DCR. This procedure has been found to be technically reliable giving satisfactory post-operative results in 16 patients suffering from nasol-acrimal duct obstruction. The follow up was up to 12 months with a mean of 5 months. Three patients who had residual post-operative epiphora were considered as failures. There were no major complications and minor complications included one case of periorbital ecchymosis, one unretrieved silicone tube and a minor vestibule abrasion. The preliminary results suggest that the endoscopic drill-assisted DCR could offer a reliable treatment in patients with epiphora due to nasolacrimal duct obstruction.     

Transvaginal endoscopic cholecystectomy using a simple magnetic traction system

Abstract

Natural orifice transluminal endoscopic surgery (NOTES) is still at an early stage of clinical development. The development of new instruments is required to overcome some of the current limitations of NOTES. We thus performed transvaginal endoscopic cholecystectomies to determine the feasibility of using a magnetic traction system. Experiments were performed in a non-survival porcine model (n = 4). The magnet-fixed endoscopic clip was attached to the apex of the gallbladder fundus and held together with the external handheld magnet across the abdominal wall. The gallbladder fundus was then retracted to the cephalic direction by moving the external handheld magnet and the gallbladder was dissected from the liver bed. The gallbladder was placed in the endocatch material and delivered through the vagina. NOTES cholecystectomies via the transvaginal approach were successfully performed in a porcine model. The magnetic traction system was effective in achieving adequate exposure in all pigs. The magnetic traction system provides vigorous, multi-axial traction as required for the cholecystectomy procedure. There were no complications during the procedure other than minor bleeding from the liver bed. The mean procedure time was 133.8 minutes (range, 105 to 175 minutes). Our study successfully demonstrated the feasibility of the magnetic traction system in NOTES.     

内镜下经鼻入路切除颅咽管瘤(附65例报告)

目的探讨内镜下经鼻入路切除颅咽管瘤的临床经验和应用价值。方法回顾性分析2012年2月-2016年5月使用内镜下经鼻入路切除的65例颅咽管瘤患者的临床资料,综合评价治疗效果、并发症发生率及随访结果。结果肿瘤全切52例(80.0%),次全切11例(16.9%),部分切除2例(3.1%);术中发现垂体柄共57例,保留41例(71.9%);术后视力改善31例(47.7%),6例维持在术前水平,1例术后视力下降;术后出现垂体功能下降21例(32.3%);术后短暂性尿崩45例(69.2%),长期尿崩9例(13.8%);4例(6.2%)患者出现脑脊液漏,均伴随颅内感染,均予以再次修补,成功3例,死亡1例;围手术期死亡3例(4.6%)。52例患者接受随访,时间4.0~45.0个月,平均20.8个月,44例(84.6%)恢复正常生活,8例(15.4%)出现肥胖,2例复发,尚无死亡病例。结论内镜下经鼻入路切除颅咽管瘤安全、有效、微创,具有其独到的优势。     

内镜下扩大经鼻蝶入路切除鞍上三脑室内颅咽管瘤

目的：探讨完全内镜下扩大经鼻蝶入路切除位于鞍上三脑室内的颅咽管瘤的可行性和有效性。方法：采用完全内镜下扩大经鼻蝶入路切除位于鞍上三脑室内的颅咽管瘤1例。结果：肿瘤被全部切除,术后随访6个月,患者在内分泌替代治下生活正常。结论：完全内镜下扩大经鼻蝶入路可以安全有效地切除位于鞍上三脑室内的颅咽管瘤。对于选择性的颅咽管瘤病例,该手术入路是一种切除肿瘤的更新、更微创的手术入路。