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1.
《Indian heart journal》2018,70(2):308-315
BackgroundCatheter based treatment has gained wide acceptance for management of patent ductus arteriosus (PDA) ever since its introduction. Percutaneous closure in adults can be challenging because of anatomical factors including large sizes, associated pulmonary arterial hypertension (PAH) and co-morbidities. This study aimed to provide comprehensive contemporary data on the safety and efficacy of percutaneous device closure of PDA in adult and adolescent population at a large referral center.MethodsThis single-center retrospective analysis included 70 patients (33 adolescents and 37 adults) who underwent successful percutaneous device closure of PDA between January 2011 and February 2017.Baseline patient demographics, clinical characteristics, procedural and device related variables, and immediate outcomes during hospital stay were recorded. Patients were followed up for residual shunt and complications.ResultsOf 70 PDA device closure cases, 71.4% were females; the mean age was 23 years (range:10-58years). Devices used were 4-Cook’s detachable coils, 64-occluders (ADO-I and II, Lifetech, Cardi-O-Fix), 1-vascular plug and 1-ventricular septal occluder device. Device success was achieved in all including those with very large PDAs. At 24-h post-procedure, the success rate of transcatheter intervention was 95.7%. At 6-months follow up, complete closure was observed in all (mean follow up duration-531 days). In patients with severe PAH, significant immediate and sustained reduction of the mean pulmonary pressure was observed(77 mmHg to 33 mmHg;P = 0.014). No procedure-related complications including death, device embolization and stenosis of aorta or pulmonary artery occurred.ConclusionsIn contemporary practice, percutaneous device closure is an effective and safe treatment option for adolescent and adult PDA patients. 相似文献
2.
Chuang YC Yin WH Hsiung MC Tsai SK Lee KC Huang HJ Ou CH Chang CY Wei J Chou YP 《Echocardiography (Mount Kisco, N.Y.)》2011,28(5):E101-E103
Residual patent ductus arteriosus (PDA) after surgical ligation is not common, but the anatomy of the residual duct may be distorted by the surgical ligation resulting in a difficult transcatheter closure. Such distorted anatomy of the duct may not be demonstrated by the two-dimensional transesophageal echocardiography (2D TEE). Fortunately, live 3D TEE provided the precise anatomy of the elongated distorted residual duct, and as in the case presented herein, guided the Amplatzer ductal occluder (ADO). We concluded that live 3D TEE provided novel images of complex residual ducts and successful guidance of a ductal occluder. 相似文献
3.
Transcatheter closure of moderate to large patent ductus arteriosus with the Amplatzer duct occluder. 总被引:2,自引:0,他引:2
Jou-Kou Wang Mei-Hwan Wu Juey-Jen Hwang Fu-Tein Chiang Ming-Tai Lin Hung-Chi Lue 《Catheterization and cardiovascular interventions》2007,69(4):572-578
OBJECTIVES: To investigate the acute and follow-up results of transcatheter closure of moderate to large patent ductus arteriosus (PDA) with the Amplatzer duct occluder. METHODS: Between April 2000 and June 2005, 237 patients underwent attempted transcatheter closure of PDA, of whom Amplatzer duct occluder was used in 68 patients with moderate-to-large-sized PDA (45 females, with ages ranging from 56 days to 75 years, median 3.3 years). Moderate to large PDA is defined as ductus diameter > or =2.5 mm (> or =3 mm in early phase of this study) in infants and young children, or > or =4 mm in adolescents and adults. The size of device selected was generally at least 1-2 mm larger than ductus diameter. RESULTS: The ductus diameter ranged from 2.5 to 8.5 mm (4.1 +/- 1.3 mm). Amplatzer duct occluder was successfully deployed in 66 out of 68 patients. The size of device deployed ranged from 4 to 12 mm (6.3 +/- 1.6 mm). The causes of failure in the 2 patients included calcification of ductus resulting, in failure in advancing a sheath to descending aorta in 1 and kinking of a Cook sheath in the other. Distal embolization of the device occurred several hours later in one. After the device was retrieved percutaneously, the patient was sent to surgery. No other significant complications occurred. In the 3-month follow-up, complete occlusion was achieved in all patients. No patient had left pulmonary artery stenosis. CONCLUSIONS: Transcatheter closure of moderate-to-large-sized ductus with Amplatzer ductus occluder is effective and safe. 相似文献
4.
目的:应用Amplatzer封堵器在高原地区治疗动脉导管未闭(PDA)并评价其疗效。方法:本组40例,年龄1.5~44(22.5±14.2)岁,PDA最窄处内径5~14(9.3±3.3)mm,均用Amplatzer封堵器介入治疗。结果:19例成功,1例严重阻塞性肺动脉高压不适宜封堵。术后即刻降主动脉造影显示35例封堵完全无残余分流,4例少量残余分流。1例术后1h封堵器脱落入右肺动脉,第3小时急诊外科手术关闭PDA并取出封堵器。24 h彩色多普勒检查显示封堵36例患者均无分流,随访2个月~1年半,无一例分流。结论:高原地区PDA发病率高,并发肺动脉高压早且多,巨大PDA(内径>0.8 cm)比率高,用Amplatzer封堵器治疗PDA是高原地区一种适应性强、安全有效的介入治疗方法。 相似文献
5.
年龄和未闭动脉导管大小对蘑菇伞封堵器选择的影响 总被引:5,自引:1,他引:4
目的 探讨年龄及未闭动脉导管大小对蘑菇伞封堵器尺寸选择的影响及临床意义。方法 6 2例动脉导管未闭 (PDA)的患者中 ,儿童 36例 ,年龄 (5 5± 2 7)岁 ;成人 2 6例 ,年龄 (19 7± 12 3)岁。应用X线降主动脉造影测量PDA的最小直径 (D1) ,并与最终所选择的封堵器直径 (D2 )比较 ;以彩色多普勒血流显像 (CDFI)观察残余分流情况。结果 (1)在 6 2例患者的 6 9次封堵尝试中 (更换封堵器 7例次 ) ,即刻CDFI观察到边缘性残余分流束宽度 >2mm者 8例、≤ 2mm者 2 4例 ;中央性残余分流束 15例。在 30min内 ,中央性残余分流束均可自行消失 ,≤ 2mm的边缘性残余分流束多数可自行消失 ,>2mm的边缘性残余分流束不能自行消失。 (2 )在PDA的最小直径相同时 ,儿童组所需封堵器的尺寸比成人组平均大 1 5mm。 (3)在达到满意的封堵效果时 ,儿童组D2 =1 5 7D1+0 5 7,成人组D2 =1 6 0D1- 1 0 1。结论 传统的封堵器尺寸选择标准具有局限性 ;在用蘑菇伞封堵器封堵PDA时 ,年龄和PDA的大小对封堵器尺寸的选择具有显著影响 ;达到满意的封堵效果时 ,所选择封堵器的尺寸遵循一定的线性规律。 相似文献
6.
Raghda Ghonimy Elsheikh Ahmed Z. Darweish Mohamed Elsetiha Hazem Kamel 《Journal of the Saudi Heart Association》2014,26(4):204-211
In this study we compared the real time three dimensional echocardiogram data in evaluation of patent ductus arteriosus with the gold standard angiography.
Methods
This study included 25 patients with PDA referred to Tanta University Hospital for elective cardiac catheterization. The patients comprised seven males and 18 females, with a mean age of 3.7 ± 0.36 years. The study duration was six months. All patients underwent full 2D echocardiogram as well as real time three-dimensional echocardiogram (RT3DE).Essential measurements included the pulmonary end of the duct, duct length, aortic end and aortic ampulla as well as the anatomical type of the PDA. Data obtained by RT3DE were compared against 2D echocardiogram and angiography.Results
There was no significant difference between 3D echocardiogram and angiography (P = 0.001) in the pulmonary end of the duct measurement. Neither were there any significant differences between the length of the duct or the aortic end measured by 3D echocardiogram and by angiography (P = 0.001 in both). While there was adequate agreement between both 2D and 3D echocardiogram and angiography in determining the anatomical type of the PDA, 3D echocardiogram determined type A and type E ductus more accurately than 2D echocardiogram. The feasibility of Q lab analysis of PDA was 96%, while the feasibility of gated color flow 3D acquisitions in determining anatomical types was 64%.Conclusion
There was complete agreement on location, size, morphology and surrounding structure of PDA between 2D and 3D echocardiogram, and angiography. This result illustrates the need for the proper placement of the device in catheterization laboratories. 相似文献7.
Transcatheter closure of patent ductus arteriosus with the Rashkind occluder: Acute results and angiographic follow-up in adults 总被引:2,自引:0,他引:2
Sievert H.; Ensslen R.; Fach A.; Merle H.; Scherer D.; Schrader R.; Spies H.; Schulze R.; Utech A. 《European heart journal》1997,18(6):1014-1018
We performed catheter closure of a patent ductus arteriosuswith a Rashkind occluder in 51 adult patients (aged 14 to 76years). The diameter of the ductus ranged from 2 to 13 mm (mean4·5±2·0 mm), QP:QS from 1·0 to 2·6(mean 1·6±0·3). The procedure was successful in 50/51 patients, in one of themat a second attempt. In one patient, the ductus could not beclosed even with additional occluders. This patient was sentfor surgery. In two patients with a large ductus, two Rashkindumbrellas were implanted simultaneously. Immediately after ductusclosure, there was a residual shunt in 40/50 patients decreasingto 26/50 after 20 min. Two of the patients with a residual shuntsuffered from haemolysis. In 16 patients, the residual shuntdisappeared spontaneously within some months. In 15 patients,additional occluders (a second occluder in 12, a third occluderin one, and a fourth and fifth occluder in another) were implantedduring the initial procedure or during follow-up. All patientswere followed until angiography proved complete closure of theductus. At the time of the last follow-up angiogram, the ductuswas occluded in 49/50 patients; one patient refused a follow-upangiogram. Ductus occlusion with the Rashkind umbrella can be considereda technique with a high success rate and low rate of complicationsin adults. However, a residual shunt is not uncommon. Additionaloccluders have to be implanted in many patients. 相似文献
8.
《Revista portuguesa de cardiologia》2021,40(8):561-568
IntroductionPatent ductus arteriosus, a persistent communication between the descending thoracic aorta and the pulmonary artery, is one of the most common congenital heart defects. Transcatheter occlusion is an effective alternative to surgery and is currently standard of care for most patients. The authors present the results from a single center after twelve years of experience using this technique.MethodsRetrospective analysis of medical records from all patients referred to a tertiary center for percutaneous ductus closure between January 2006 and September 2018.ResultsA total of 221 patients were referred, with a mean age of 5.5 years-old (16 patients were infants, with the youngest aged four months). A Nit-Occlud® coil was used 139 times (62.9%), an Amplatzer™ duct occluder 79 times (35.7%), and vascular plugs were used three times. Percutaneous closure was achieved in every treated patient, with 1.4% maintaining residual shunting. Although higher overall coil device implantation was noted, duct occluder usage has been greater since 2011. Of all the coils, 55% were either 4x4 or 5x4 mm, and 73% of all Amplatzer duct occluders were either 6x4 or 8x6 mm, which correlates to the majority of patients having a small to moderately sized ductus. No complications were noted during the procedure, with a 1.8% post-procedure complication rate (one device embolization after 48 hours and three cases of loss of arterial pulse).ConclusionsPercutaneous patent ductus arteriosus closure was safe and effective in this setting, with a low global complication rate and similar outcomes to most equivalent centers. 相似文献
9.
Transcatheter occlusion of patent ductus arteriosus using a new angled Amplatzer duct occluder: initial clinical experience. 总被引:18,自引:0,他引:18
Jozef Masura Pavol Gavora Tomaz Podnar 《Catheterization and cardiovascular interventions》2003,58(2):261-267
In the present study, we report the initial clinical experience with the new angled Amplatzer duct occluder (ADO) for the percutaneous closure of patent ductus arteriosus (PDA). Percutaneous closure of PDA using standard ADO in infants and in patients with small PDA ampulla is difficult, or even impossible, due to protrusion of the aortic disk into the descending thoracic aorta. The aortic disk of an angled ADO is angled at 32 degrees to the body of the device and concave toward the aorta to prevent protrusion of the disk into the aorta. Percutaneous closure of PDA was attempted in nine patients with a median age of 5.2 years (range, 0.5-12.7) and median weight of 20 kg (range, 4.9-55). Selection of the occluder and the implantation technique were similar to the standard ADO. The minimal PDA diameter ranged from 2.1 to 3.7 mm (median, 2.5 mm). Occluders were successfully implanted in all patients. Immediate complete PDA closure was achieved in all patients. There were no complications. The new angled ADO is a safe and effective device for PDA closure, particularly suitable for infants and patients with small PDA ampulla. Further studies and long-term follow-up are necessary to confirm our initial experience. 相似文献
10.
目的 :应用 Amplatzer封堵器经导管治疗动脉导管未闭 (PDA)术后随访。方法 :全组 16 9例。PDA最窄处直径为 4 .7± 3.8(2 .0~ 13.0 ) mm。封堵后 10 min行降主动脉造影 ,术后 2 4 h及 1,3,6月 ,1年行超声心动图检查随访。结果 :16 6例 PDA采用 Amplatzer PDA封堵器治疗 ,3例采用 Am platzer房间隔缺损封堵器治疗。 1例 PDA术中证实伴有阻力性肺动脉高压未行介入治疗。术后 10 m in降主动脉造影示 ,5 4例存在微~少量残余分流 ,114例封堵完全无残余分流。术后 2 4 h13例存在微~少量残余分流 ,余超声心动图未见残余分流及再通。 1例封堵术后 10h并发溶血 ,4 8h后行外科 PDA缝合术。术后 1月超声心动图检查 5例存在少量残余分流 ,术后 3月 4例存在少量残余分流 ,6月及 1年 3例存在少量残余分流 ,最后行 PFM弹簧圈治疗未再见残余分流。无并发症发生。结论 :应用 Am platzer封堵器治疗 PDA是一种安全有效的介入方法 相似文献
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12.
Transcatheter closure of persistent ductus arteriosus in infants using the Amplatzer duct occluder 总被引:6,自引:0,他引:6
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AIM—To evaluate whether transcatheter closure with the Amplatzer duct occluder offers an alternative to surgical treatment in infants with a persistent ductus arteriosus.
METHODS—12 patients under 1 year of age (age 1-11 months, body weight 2.6-8.7 kg) with clinical and echocardiographic findings of a significant duct were considered for transcatheter closure with the Amplatzer occluder. The device is made of a Nitinol and polyester fabric mesh and provides occlusion by stenting the duct. Measured angiographically, the narrowest diameter of the ducts ranged from 1.5-5 mm; in six patients pulmonary hypertension was also present.
RESULTS—The devices were implanted and complete duct occlusion was demonstrated during follow up in 10 patients. Procedure related difficulties occurred in nine of the 12 cases and led to relatively long procedure and fluoroscopy times (procedure time 50-180 minutes, median 80 minutes; fluoroscopy time 4.9-49 minutes, median 16 minutes). In two infants transcatheter closure could not be achieved and surgical duct ligation had to be carried out.
CONCLUSIONS—In small infants with a persistent ductus arteriosus the Amplatzer duct occluder offers an alternative to surgical treatment, but further improvement of the implantation system is necessary before the procedure can be recommended as the treatment of choice.
Keywords: persistent ductus arteriosus; transcatheter closure; infants; Amplatzer duct occluder 相似文献
METHODS—12 patients under 1 year of age (age 1-11 months, body weight 2.6-8.7 kg) with clinical and echocardiographic findings of a significant duct were considered for transcatheter closure with the Amplatzer occluder. The device is made of a Nitinol and polyester fabric mesh and provides occlusion by stenting the duct. Measured angiographically, the narrowest diameter of the ducts ranged from 1.5-5 mm; in six patients pulmonary hypertension was also present.
RESULTS—The devices were implanted and complete duct occlusion was demonstrated during follow up in 10 patients. Procedure related difficulties occurred in nine of the 12 cases and led to relatively long procedure and fluoroscopy times (procedure time 50-180 minutes, median 80 minutes; fluoroscopy time 4.9-49 minutes, median 16 minutes). In two infants transcatheter closure could not be achieved and surgical duct ligation had to be carried out.
CONCLUSIONS—In small infants with a persistent ductus arteriosus the Amplatzer duct occluder offers an alternative to surgical treatment, but further improvement of the implantation system is necessary before the procedure can be recommended as the treatment of choice.
Keywords: persistent ductus arteriosus; transcatheter closure; infants; Amplatzer duct occluder 相似文献
13.
目的探讨应用Amplatzer封堵器介入治疗先天性心脏病(CHD)动脉导管未闭(PDA)及房间隔缺损(ASD)的可行性并评价其疗效。方法44例CHD患者(PDA14例,ASD30例)。其中PDA患者在X线透视及造影监视下植入Amplatzer封堵器;ASD患者在X线透视及经胸超声心动图(TTE)指引下经导管植入Amplatzer封堵器。术后重复TTE、ECG、及X线平片检查以评价疗效。结果全组技术成功率100%。其中1例PDA患者术后2小时出现溶血,经内科保守治疗72小时后好转。术后随访显示肺动脉压力显著下降,PDA患者左心房(LA)、左心室舒张末期内径(LVED)及ASD患者右心室舒张末期内径(RVEDD)均明显回缩。除1例发生溶血的PDA患者6个月后仍存在少量残余分流外,其余病例均封堵完全;术后X线检查显示全部患者心胸比例不同程度缩小及肺血减少。结论应用Amplatzer封堵器经导管治疗PDA和ASD是一种安全简便、疗效可靠的介入治疗方法。 相似文献
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Peter N. Dean MD Michael C. Slack MD 《Catheterization and cardiovascular interventions》2013,82(3):480-484
A 7‐month‐old patient in congestive heart failure due to a moderate sized patent ductus arteriosus (PDA) underwent uncomplicated implantation of an Amplatzer Ductal Occluder (ADO1). Two months after percutaneous device PDA closure, left pulmonary artery (LPA) stenosis was discovered. Rather than spontaneous improvement as reported in previous cases, our patient's LPA stenosis progressed in severity 7 months after ADO1 placement. A catheterization demonstrated a 32 mm Hg peak gradient from her main pulmonary artery to her LPA. She underwent successful stent angioplasty of her LPA with an excellent result and preserved PDA closure. This case demonstrates that stent angioplasty is a feasible an effective method of relieving LPA obstruction caused by a PDA occluder device. Additionally, despite slight deflection by the stent, the ADO1 device continued to provide complete ductal closure. Stent angioplasty should be considered in patients who have LPA stenosis caused by ADO1 occluder device that does not improve over time. © 2013 Wiley Periodicals, Inc. 相似文献
17.
特殊形态动脉导管未闭的介入治疗 总被引:2,自引:0,他引:2
目的探讨特殊形态动脉导管未闭(PDA)的介入治疗方法,评价其临床应用价值。方法7例应用标准型Amplatzer导管封堵器难以完成介入治疗的PDA患者,根据造影显示PDA形态及临床特点,相应选用成角型Amplatzer导管封堵器以及偏心型导管封堵器进行介入治疗,术后以心脏超声随诊评价疗效。结果7例患者皆成功完成介入治疗,无严重并发症发生;其中2例应用成角型Amplatzer导管封堵器,5例应用偏心型导管封堵器;2例经二次手术完成,余患者一次治疗完成。7例患者中,封堵术后即刻造影显示有2例封堵完全,术后24h心脏超声检查示6例封堵完全,术后3个月复查皆封堵完全。结论需要设计和生产不同形态和大小的封堵装置,以扩大PDA介入治疗的适应证。 相似文献
18.
Mark H Hoyer 《Catheterization and cardiovascular interventions》2005,65(4):577-580
We report the novel use of an Amplatzer vascular plug for closure of a large tubular patent ductus arteriosus in a small child. 相似文献
19.
Transesophageal echocardiography through nasal way as a guide to percutaneous closure of patent foramen ovale 总被引:2,自引:0,他引:2
Tallarico D Chiavari PA Mollo P Campolongo G Greco C Gaudio C 《Echocardiography (Mount Kisco, N.Y.)》2006,23(9):790-792
Percutaneous device closure of patent foramen ovale (PFO) has become an effective and safe alternative to medical or surgery treatment. Transesophageal echocardiography (TEE), as commonly used to guide this procedure, has the limitation to require general anesthesia. Recently, intracardiac echocardiography (ICE) with AcuNav probe was used to guide percutaneous PFO closure. We report a 42 year-old man with two previous cryptogenetic strokes in whom both diagnosis and guidance of PFO closure were performed by means of TEE using the AcuNav catheter introduced through nasal way (TEENW). This technique, that does not require general anesthesia, provided adequate and complete view of the Amplatzer procedure. TEENW might offer a feasible and equivalent echocardiographic alternative either to standard TEE or ICE as a guide to percutaneous PFO closure. 相似文献
20.
Transcatheter closure of large patent ductus arteriosus at high altitude with a novel nitinol device
Alexandra Heath MD PhD Nora Lang MD PhD Daniel S. Levi MD PhD Miguel Granja MD PhD Prof Jorge Villanueva MD Joaquin Navarro MD Gabriel Echazú MD Rainer Kozlik‐Feldmann MD PhD Prof Pedro del Nido MD Franz Freudenthal MD PhD 《Catheterization and cardiovascular interventions》2012,79(3):399-407
Background : Patent ducti arteriosi (PDAs) are more frequent and larger at high altitude than at sea level. A novel PDA closure device, the Nitocclud PDA‐R, is designed specifically for both large and medium size PDAs. The initial clinical experience with a new nitinol‐based device in high altitude patients with large PDAs is described. Methods : The Nitocclud PDA‐R is a self‐expandable, self‐centering, repositionable occluder made of one nitinol wire without use of welding. It contains several polyester membranes, is delivered with a central guide wire and is released by retraction of the central wire into the delivery catheter. The efficacy of this device was evaluated at several high altitude centers. Results : Fifty‐one patients without other congenital cardiac defects underwent transcatheter closure of PDA. Complete occlusion of the PDA was achieved in 98% of the patients. Nearly 49% of the patients had no shunt immediately after device implantation. Echocardiography revealed a complete closure rate by Doppler interrogation of 69% after 24 hr, 96% after 6 months, and 98% after 1 year. In two cases, device embolization was observed after release, and in both cases the device was easily retrieved with standard interventional techniques. There have been no episodes of delayed device migration, endocarditis, hemolysis, wire fracture, device disruption, or death. Conclusions : The Nitocclud PDA‐R device is safe and effective and can easily close very large PDAs. This device has a high rate of complete occlusion within 1 year and is easily retrieved if embolized. © 2011 Wiley Periodicals, Inc. 相似文献