儿童冠状动脉异常起源肺动脉的16层螺旋CT诊断

目的 评价儿童冠状动脉异常起源肺动脉的多层螺旋CT(MSCT)诊断价值.资料与方法 MSCT应用于8例冠状动脉异常起源肺动脉患儿检查中,平均年龄4.12岁(5个月～10岁),其中4例采用无心电门控CT血管成像,MSCT参数:准直0.625～1.25mm,层厚0.625～1.25mm,螺距为0.562,旋转速度0.5s/r,床进5.62mm/r,0.31～0.625mm重建间隔,4例采用回顾性心电门控.结果 8例冠状动脉起始、右冠状动脉近端、左冠状动脉主干、左前降支及左回旋支近端显示率100%.7例左冠状动脉异常起源于肺动脉瓣窦上的肺动脉总干,1例右冠状动脉异常起源于肺动脉总干右后壁,1例伴右上肺静脉异位引流入上腔静脉,1例伴右冠状动脉高位开口.结论 冠状动脉异常起源肺动脉为少见的先天性心脏病,MSCT可作为一种可靠的,有潜力的无创伤性诊断方法 应用于其诊断中.     

多层螺旋CT在小儿先天性心血管畸形中的应用

目的 探讨多层螺旋CT (MSCT)对小儿先天性心血管畸形的应用价值.资料与方法 对22例临床诊断为心血管畸形的患者进行胸部CT扫描.结果 在手术证实的39处心腔外大血管畸形中, MSCT与手术的符合率为94.8%,经胸超声心动图的诊断符合率为82.1%;对手术证实的28处心腔内畸形,MSCT的诊断符合率89.3% ,超声心动图的诊断符合率为100%.MSCT与经胸心动超声图在诊断心腔外大血管畸形时有显著性差异(P<0.05),而在诊断心腔内畸形时差异无显著性意义(P>0.05).结论 MSCT能直观地显示主动脉、肺动脉等大血管及其分支的走行、形态,为心外大血管畸形的诊断提供了客观依据,MSCT结合经胸超声心动诊断先天性心血管畸形已基本取代心血管造影.     

128层双源CT心电门控序列扫描与大螺距扫描对先天性心脏病合并冠状动脉发育异常患儿的对比研究

目的:对比128层双源CT心电门控序列扫描和大螺距扫描对先天性心脏病患儿冠状动脉发育异常的显示准确率及图像质量.方法:回顾性分析临床初诊为先天性心脏病合并冠状动脉发育异常并经DSA证实及手术治疗的患儿56例,其中30例采用心电门控序列扫描(A组),26例采用大螺距扫描(B组).测量2组升主动脉根部CT值及噪声,计算SN...     

16层螺旋CT诊断复杂型先天性心脏病的临床应用

先天性心脏病(简称先心病)常伴发多种畸形,特别是心外大血管发育畸形,手术前的定位定性诊断尤其重要.目前对先心病的检查方法主要有彩色多普勒超声心动图、多层螺旋CT(MSCT)、电子束CT(EBCT)、磁共振(MRI)、心血管造影等.     

64层螺旋CT诊断复杂先天性心脏病的临床价值

目的 探讨64层螺旋CT(64SCT)对比增强及后处理技术对复杂先天性心脏病(CCHD)的诊断价值.方法 39例CCHD手术前均行经胸心脏二维超声(TTE)检查和648CT对比增强扫描检查,其中CT扫描时有8例采用心电门控技术.手术后按心内畸形、心脏大血管连接部畸形及大血管部分畸形分别统计CT及TTE 2种检查方法及有否使用心电门控技术的诊断正确率,并使用SPSS13.0版软件包对结果行χ~2检验.结果 手术证实畸形共102处,其中心脏部分畸形47处,CT和TTE的诊断准确率分别为85.1%和95.7%,2种检查的诊断正确性差异无显著性意义(χ~2=2.68,P>0.05);心脏大血管连接部分及大血管部分畸形共计55处,CT和TTE的诊断准确率分别为98.2%和78.2%,64SCT诊断正确率明显高于TTE(χ~2=14.64,P<0.01).未使用和使用心电门控在定性诊断准确性差异上无显著意义(χ~2=1.84,P>0.05),但采用心电门控技术CT扫描图像更清晰.结论 64CT对CCHD的检查具有较高的诊断价值.扫描时是否采用心电门控技术对CCHD的定性诊断无明显统计学差别.     

128层MSCT虚拟仿真内镜技术在婴幼儿先天性心脏病的应用

目的:探讨128层MSCT虚拟仿真内镜技术(VE)对婴幼儿先天性心脏病的诊断价值.方法:回顾性分析67例先天性心脏病患儿128层螺旋CT和经胸壁超声心动图(TTE)资料,并与手术结果作对照.采用5分单盲法评价VE图像质量,比较心房心室和大血管的差异,建立VE飞行路径规划.结果:VE诊断主要心脏结构异常的总符合率51.7...     

复杂性先天性心脏病进行多层螺旋CT诊断的临床价值

目的探究复杂性先天性心脏病进行多层螺旋CT诊断的临床价值。方法选取2016年6月~2017年12月收治的38例先天性心脏病患者作为观察对象,所有患者均经外科手术证实,采用Somatom Definition AS+ 128层螺旋CT扫描仪、Philips公司生产的彩色多普勒超声心动图诊断仪对所有患者分别行超声心动图(UCG)、多层螺旋CT检查。统计并比较多层螺旋CT及UCG两种检查方法对38例CCHD患者心内、外畸形确诊、漏诊、误诊情况,进一步统计两者联合诊断与单独诊断符合情况。结果38例CCHD患者均经手术证实,共发现心脏畸形141处,其中心内畸形71处,心脏与大血管连接畸形及心外大血管畸形(心外畸形)70处。其中在心内畸形诊断中,UCG诊断符合率为95.77%(68/71)略高于多层螺旋CT检查的91.55%(65/71),但二者差异无统计学意义( P >0.05);在心外畸形诊断中,多层螺旋CT诊断符合率98.57%(69/70)明显高于UCG的85.71%(60/70),差异具有统计学意义( P <0.05);多层螺旋CT联合UCG的诊断符合率高达98.58%,均高于二者单独诊断的95.04%、90.78%。结论多层螺旋CT在复杂型先天性心脏病的诊断中具有较高的临床价值,特别是在发现心外畸形诊断中优势显著,临床中可与超声心动图联合应用以提高其对心内畸形的确诊率。     

64层螺旋CT在先天性心脏病诊断中的价值

目的 探讨64层螺旋CT在诊断先天性心脏病中的临床价值.方法 回顾性分析20例先天性心脏病的64层螺旋CT血管造影资料,并与超声心动图(ECG)及手术结果相对照.结果 经64螺旋CT心脏造影检查,显示房间隔缺损4例,室间隔缺损6例,法洛四联症7例,右室双出口伴室间隔缺损1例,动脉导管未闭2例,主动脉弓缩窄1例,主动脉弓离断1例.6例显示冠状动脉发育异常,7例显示外周肺动脉不同程度的狭窄.1例患者房间隔缺损(约3 mm)漏诊,1例患者室间隔缺损(约3 mm)漏诊.诊断准确率为90.00%.结论 64层螺旋CT心脏造影在先天性心脏病的诊断中具有重要的价值.     

64层螺旋CT诊断复杂先天性心脏病及与超声心动图和手术对照

目的探讨64层螺旋CT对复杂先天性心脏病(简称复杂先心病)的诊断价值。资料与方法对25例复杂先心病患者的心脏CT和超声心动图(TTE)进行回顾性分析,并与手术结果对照。全部病例均经手术证实。结果25例患者中手术证实畸形79处,64层螺旋CT与TTE诊断的准确率分别为96%和73%。其中,心脏部分畸形29处,64层螺旋CT漏误诊2处,TTE漏误诊4处,两种检查的诊断准确率差异无统计学意义。心脏-大血管连接部及大血管部分畸形50处,64层螺旋CT漏误诊1处,TTE漏误诊17处,两种检查的诊断准确率差异有统计学意义。结论64层螺旋CT在复杂先心病诊断中畸形的检出率优于TTE,诊断准确率达96%,特别是对主动脉、肺动脉及肺静脉畸形的显示具有明显优势。     

320排CT在先天性心脏病诊断中的应用

目的:探讨320排CT对先天性心脏病的临床诊断价值。方法:回顾性分析15例先天性心脏病患者的320排CT扫描资料,并与经胸超声心动图(TTE)及手术结果进行对照研究。结果:15例经手术证实的心内外结构异常共72个,其中心内结构异常27个,心外结构异常45个。320排CT、TTE对心内畸形的诊断符合率分别为96.3%(26/27)和92.6%(25/27),差异无显著性意义(χ2=2.982,P>0.05)。320排CT对心脏大血管连接部位畸形及心外大血管畸形的诊断符合率[100%(45/45)]明显高于TTE[53.3%(24/45)],差异有显著性意义(χ2=31.28,P<0.05)。320排CT及TTE对先心病总的诊断符合率分别为98.6%和68.0%,差异有显著性意义(χ2=28.09,P<0.05)。结论:320排CT对心外大血管结构异常的检出显著优于TTE,对心内结构异常的检出也有良好的效果,320排CT结合TTE可显著提高对小儿先心病的诊断准确性。     

Knee injury and Osteoarthritis Outcome Score (KOOS) - validation of a Swedish version

The Knee injury and Osteoarthritis Outcome Score (KOOS) is a self-administered instrument measuring outcome after knee injury at impairment, disability, and handicap level in five subscales. Reliability, validity, and responsiveness of a Swedish version was assessed in 142 patients who underwent arthroscopy because of injury to the menisci, anterior cruciate ligament, or cartilage of the knee. The clinimetric properties were found to be good and comparable to the American version of the KOOS. Comparison to the Short Form-36 and the Lysholm knee scoring scale revealed expected correlations and construct validity. Item by item, symptoms and functional limitations were compared between diagnostic groups. High responsiveness was found three months after arthroscopic partial meniscectomy for all subscales but Activities of Daily Living.     

Endovascular management of carotid-cavernous fistulas

Objective To investigate endovascular treatment of traumatic direct carotid-cavernous fistulas （CCF） and their complications such as pseudoaneurysms. Methods： Over a five-year period, 22 patients with traumatic direct CCFs were treated endovascularly in our institution. Thirteen patients were treated once with the result of CCF occluded, 8 twice and 1 three times. Treatment modalities included balloon occlusion of the CCF, sacrifice of the ipsilateral internal carotid artery with detachable balloon, coll embolization of the cavernous sinus and secondary pseudoaneurysms, and covered-stem management of the pseudoaneurysms. Results All the direct CCFs were successfully managed endovascularly. Four patients developed a pseudoaneurysm after the occlusion of the CCF with an incidence of pseudoaneurysm formation of 18.2% （4/22）. A total number of 8 patients experienced permanent occlusion of the ICA with a rate of ICA occlusion reaching 36.4% （8/22）. Followed up through telephone consultation from 6 months to 5 years, all did well with no recurrence of CCF symptoms and signs. Conclusion Traumatic direct CCFs can be successfully managed with endovascular means. The pseudoaneurysms secondary to the occlusion of the CCFs can be occluded with stent-assisted coiling and implantation of covered stents.     

The acutely limping child

Acute limping may be the result of multiple pathologies in children. The differential diagnosis varies based on the age of the child. Irrespective of age, the initial imaging work-up includes AP and frog leg radiographs of the pelvis and ultrasound; MRI may sometimes be helpful. In children less than 3 years, infections and trauma are most frequent. MRI is the imaging modality of choice when osteomyelitis is clinically suspected. Between the ages of 3 and 10 years, transient synovitis of the hip and Legg-Calvé-Perthes disease are main considerations but infection, inflammation and focal bony lesions are also considered. In children over 10 years, slipped capital femoral epiphysis also is considered.     

Do Balance Board Training Programs Reduce the Risk of Ankle Sprains in Athletes?

Introduction Ankle sprains are the most common musculo-skeletal injury that occurs in athletes,particularly in sports that require jumping and landing on one foot such as soccer,and basketball(1-4).These injuries often result in significant time loss from participation,long-term disability,and have a major impact on health care costs and resources(5-8).     

High Intensity Interval Training:New Insights

KEY POINTS ·High-intensity interval training(HIT)is characterized by repeated sessions of relatively brief，intermittent exercise.often performed with an“a11 out”effort or at an intensity close to that which elicits peak oxygen uptake(i.e.，≥90%of VO2 peak).     

Developmental validation of the PowerPlex(®) ESI 16 and PowerPlex(®) ESI 17 Systems: STR multiplexes for the new European standard

In response to the ENFSI and EDNAP groups’ call for new STR multiplexes for Europe, Promega^® developed a suite of four new DNA profiling kits. This paper describes the developmental validation study performed on the PowerPlex^® ESI 16 (European Standard Investigator 16) and the PowerPlex^® ESI 17 Systems. The PowerPlex^® ESI 16 System combines the 11 loci compatible with the UK National DNA Database^®, contained within the AmpFlSTR^® SGM Plus^® PCR Amplification Kit, with five additional loci: D2S441, D10S1248, D22S1045, D1S1656 and D12S391. The multiplex was designed to reduce the amplicon size of the loci found in the AmpFlSTR^® SGM Plus^® kit. This design facilitates increased robustness and amplification success for the loci used in the national DNA databases created in many countries, when analyzing degraded DNA samples. The PowerPlex^® ESI 17 System amplifies the same loci as the PowerPlex^® ESI 16 System, but with the addition of a primer pair for the SE33 locus. Tests were designed to address the developmental validation guidelines issued by the Scientific Working Group on DNA Analysis Methods (SWGDAM), and those of the DNA Advisory Board (DAB). Samples processed include DNA mixtures, PCR reactions spiked with inhibitors, a sensitivity series, and 306 United Kingdom donor samples to determine concordance with data generated with the AmpFlSTR^® SGM Plus^® kit. Allele frequencies from 242 white Caucasian samples collected in the United Kingdom are also presented. The PowerPlex^® ESI 16 and ESI 17 Systems are robust and sensitive tools, suitable for the analysis of forensic DNA samples. Full profiles were routinely observed with 62.5 pg of a fully heterozygous single source DNA template. This high level of sensitivity was found to impact on mixture analyses, where 54–86% of unique minor contributor alleles were routinely observed in a 1:19 mixture ratio. Improved sensitivity combined with the robustness afforded by smaller amplicons has substantially improved the quantity of data obtained from degraded samples, and the improved chemistry confers exceptional tolerance to high levels of laboratory prepared inhibitors.