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1.
J Dupont P J White K M Johnston H A Heggtveit B E McDonald S M Grundy 《Journal of the American College of Nutrition》2013,32(5):360-375
Canola oil is a newly marketed vegetable oil for use in salads and for cooking that contains 55% of the monounsaturated fatty acid; oleic acid, 25% linoleic acid and 10% alpha-linolenate [polyunsaturated fatty acid (PUFA)], and only 4% of the saturated fatty acids (SFAs) that have been implicated as factors in hypercholesterolemia. It is expressed from a cultivar of rapeseed that was selectively bred from old varieties in Canada to be very low in erucic acid–a fatty acid suspected to have pathogenic potential in diets high in the original rapeseed oil in experimental animals. Canola oil is free of those problems. It is the most widely consumed food oil in Canada, and has been approved for Generally Recognized as Safe (GRAS) status by the Food and Drug Administration (FDA) of the United States Department of Health and Human Services. The fatty acid composition of canola oil is consistent with its use as a substitute for SFAs, in meeting the dietary goals recommended by many health associations: an average diet containing about 30% of calories as fat made up of less than 10% SFAs, 8-10% PUFAs in a ratio of linoleic to linolenic acids between 4:1 and 10:1, the remainder being monounsaturated fatty acids. No single oil meets these current recommendations for ratios of PUFA/monounsaturated/polyunsaturated fatty acid ratios as the sole source of cooking and salad oil. 相似文献
2.
Food uses and health effects of corn oil 总被引:2,自引:0,他引:2
J Dupont P J White M P Carpenter E J Schaefer S N Meydani C E Elson M Woods S L Gorbach 《Journal of the American College of Nutrition》1990,9(5):438-470
This review of corn oil provides a scientific assessment of the current knowledge of its contribution to the American diet. Refined corn oil is composed of 99% triacylglycerols with polyunsaturated fatty acid (PUFA) 59%, monounsaturated fatty acid 24%, and saturated fatty acid (SFA) 13%. The PUFA is linoleic acid (C18:2n-6) primarily, with a small amount of linolenic acid (C18:3n-3) giving a n-6/n-3 ratio of 83. Corn oil contains a significant amount of ubiquinone and high amounts of alpha- and gamma-tocopherols (vitamin E) that protect it from oxidative rancidity. It has good sensory qualities for use as a salad and cooking oil. Corn oil is highly digestible and provides energy and essential fatty acids (EFA). Linoleic acid is a dietary essential that is necessary for integrity of the skin, cell membranes, the immune system, and for synthesis of icosanoids. Icosanoids are necessary for reproductive, cardiovascular, renal, and gastrointestinal functions and resistance to disease. Corn oil is a highly effective food oil for lowering serum cholesterol. Because of its low content of SFAs which raises cholesterol and its high content of PUFAs which lowers cholesterol, consumption of corn oil can replace SFAs with PUFAs, and the combination is more effective in lowering cholesterol than simple reduction of SFA. PUFA primarily lowers low-density-lipoprotein cholesterol (LDL-C) which is atherogenic. Research shows that PUFA has little effect on high-density-lipoprotein cholesterol (HDL-C) which is protective against atherosclerosis. PUFA generally improves the ratio of LDL-C to HDL-C. Studies in animals show that PUFA is required for the growth of cancers; the amount required is considered to be greater than that which satisfies the EFA requirement of the host. At this time there is no indication from epidemiological studies that PUFA intake is associated with increased risk of breast or colon cancer, which have been suggested to be promoted by high-fat diets in humans. Recommendations for minimum PUFA intake to prevent gross EFA deficiency are about 3% of energy (en%). Recommendations for prevention of heart disease are 8-10 en%. Consumption of PUFA in the United States is 5-7 en%. The use of corn oil to contribute to a PUFA intake of 10 en% in the diet would be beneficial to heart health. No single source of salad or cooking oil provides an optimum fatty acid (FA) composition. Many questions remain to be answered about the relation of FA composition of the diet to various physiological functions and disease processes. 相似文献
3.
J Dupont P J White M P Carpenter E J Schaefer S N Meydani C E Elson 《Journal of the American College of Nutrition》2013,32(5):438-470
This review of corn oil provides a scientific assessment of the current knowledge of its contribution to the American diet. Refined corn oil is composed of 99% triacylglycerols with polyunsaturated fatty acid (PUFA) 59%, monounsaturated fatty acid 24%, and saturated fatty acid (SFA) 13%. The PUFA is linoleic acid (C18:2n-6) primarily, with a small amount of linolenic acid (C18:3n-3) giving a n-6/n-3 ratio of 83. Corn oil contains a significant amount of ubiquinone and high amounts of alpha- and gamma-tocopherols (vitamin E) that protect it from oxidative rancidity. It has good sensory qualities for use as a salad and cooking oil. Corn oil is highly digestible and provides energy and essential fatty acids (EFA). Linoleic acid is a dietary essential that is necessary for integrity of the skin, cell membranes, the immune system, and for synthesis of icosanoids. Icosanoids are necessary for reproductive, cardiovascular, renal, and gastrointestinal functions and resistance to disease. Corn oil is a highly effective food oil for lowering serum cholesterol. Because of its low content of SFAs which raises cholesterol and its high content of PUFAs which lowers cholesterol, consumption of corn oil can replace SFAs with PUFAs, and the combination is more effective in lowering cholesterol than simple reduction of SFA. PUFA primarily lowers low-density-lipoprotein cholesterol (LDL-C) which is atherogenic. Research shows that PUFA has little effect on high-density-lipoprotein cholesterol (HDL-C) which is protective against atherosclerosis. PUFA generally improves the ratio of LDL-C to HDL-C. Studies in animals show that PUFA is required for the growth of cancers; the amount required is considered to be greater than that which satisfies the EFA requirement of the host. At this time there is no indication from epidemiological studies that PUFA intake is associated with increased risk of breast or colon cancer, which have been suggested to be promoted by high-fat diets in humans. Recommendations for minimum PUFA intake to prevent gross EFA deficiency are about 3% of energy (en%). Recommendations for prevention of heart disease are 8-10 en%. Consumption of PUFA in the United States is 5-7 en%. The use of corn oil to contribute to a PUFA intake of 10 en% in the diet would be beneficial to heart health. No single source of salad or cooking oil provides an optimum fatty acid (FA) composition. Many questions remain to be answered about the relation of FA composition of the diet to various physiological functions and disease processes. 相似文献
4.
T Sepp?nen-Laakso H Vanhanen I Laakso H Kohtam?ki J Viikari 《The British journal of nutrition》1992,68(3):639-654
The effects of zero-erucic acid rapeseed oil and rapeseed oil-containing margarine on plasma fatty acid composition and serum cholesterol were studied in butter users (n 43). Compliance to the substitution was followed by fatty acid analysis of total plasma and plasma phospholipids. The amount of substitute fats represented, on average, 21% of total fat and 8% of total energy intake. Changes in the relative fatty acid composition of plasma phospholipids indicated further fatty acid metabolism, and were closely related to the serum cholesterol level. The reduction in saturated fatty acids led to a significant increase in the proportion of n-3 and n-6 polyunsaturated fatty acids (PUFA) with the rapeseed oil diet, whereas the margarine caused a significant rise in n-6 PUFA only. The increase in the proportions of the two PUFA families occurred in accordance with their competitive order, most completely with the rapeseed oil diet. When butter was replaced by rapeseed oil, low-density-lipoprotein-cholesterol decreased by an average of 9.1% without a reduction in high-density-lipoprotein-cholesterol. During margarine substitution the reduction was 5.2%, on average. Of the plasma phospholipids, alpha-linolenic acid and the linoleic:stearic acid ratio, but not oleic acid, were the components most significantly correlated with serum cholesterol levels or the decrease in these levels. The results show that rapeseed oil can act primarily as a source of essential fatty acids, rather than that of monoenes, in the diet of butter users. 相似文献
5.
Yoshida H Mawatari M Ikeda I Imaizumi K Seto A Tsuji H 《Journal of nutritional science and vitaminology》1999,45(4):411-421
Eicosapentaenoic (EPA) and docosahexaenoic (DHA) acids were distributed mainly in the sn-1 and 3 positions of seal oil triacylglycerol and in the sn-2 position of fish oil triacylglycerol. Seal oil or fish oil-rich fats having constant polyunsaturated/monounsaturated/saturated fatty acids and n-6/n-3 polyunsaturated fatty acid (PUFA) ratios were fed to rats for 3 wk. Control rats were fed on a fat containing linoleic acid as the sole PUFA. Seal oil more effectively lowered serum and liver triacylglycerol concentrations than fish oil. The activities of fatty acid synthase (FAS), glucose-6-phosphate dehydrogenase (G6PDH) and hepatic triacylglycerol lipase (HTGL) were significantly lower in the seal oil group than in the control group, whereas the activity of HTGL was significantly lower and the hepatic peroxisomal beta-oxidation and activity of lipoprotein lipase (LPL) in adipose tissue were significantly higher in the fish oil group than in the control group. These observations suggest that the predominant hypotriacylglycerolemic effect of seal oil is caused by the suppression of fatty acid synthesis. 相似文献
6.
We studied the digestion of fat and fatty acids in diets containing oils with different fatty acid composition. Four barrows (initial weight 35 kg) were fitted with a simple T-cannula at the terminal ileum. Three wheat starch and fish meal-based diets were formulated to contain either 150 g fish oil, rapeseed oil or coconut oil/kg. A basal diet, which did not contain oil, was also prepared. The diets were fed according to a 4 x 4 Latin square design. Each experimental period comprised 5 d adaptation to the diets, 3 d fecal collection and 2 d digesta collection. The apparent ileal and fecal digestibilities of fat were relatively high (88 - 93%). The ileal digestibilities of total, saturated and monounsaturated fatty acids did not differ among the diets. However, the digestibilities of polyunsaturated fatty acids (PUFA) in the fish and rapeseed oil diets were higher (P < 0.05) than in the coconut oil diet. The ileal digestibilities of 18:1, 18:2 and 18:3 in the rapeseed oil diet ranged from 94 to 97%. The ileal digestion of the unsaturated long-chain fatty acids 20:5(n-3) and 22:6(n-3) in the fish oil diet was nearly complete (97 - 98%). Apparent fecal digestibilities of saturated fatty acids (76 - 89%) were lower than apparent ileal digestibilities (89 - 94%). The digestibilities of fat and fatty acids were relatively high when pigs were fed diets containing fish oil, rapeseed oil or coconut oil. There were few differences in the digestibilities of saturated, monounsaturated and PUFA in the fish oil, rapeseed oil or coconut oil diets. 相似文献
7.
Daniewski M Jacórzyński B Filipek A Balas J Pawlicka M Mielniczuk E 《Roczniki Państwowego Zak?adu Higieny》2003,54(3):263-267
The four edible oils purchased on Warsaw marked in the years 1996-2002 were investigated. We confirmed that investigated oils contained relatively small amount of saturated fatty acids (7.0-13.4%) and only traces of trans isomers. In the same time they were characterized with high content unsaturated fatty acids, both mono- and polyunsaturated. The highest content of monounsaturated acids (65%) characterized rapeseed oil, whereas polyunsaturated ones--sunflower oil (68%). Polyunsaturated acids were represented mainly by linoleic acid (C18:2). The results of investigation show that oils available on the market despite of their different manufacturers ha got the good health value. 相似文献
8.
饲料脂肪酸组成对大鼠胃肠等肿瘤生成的影响 总被引:1,自引:1,他引:0
目的: 研究脂肪酸组成对甲基亚硝基脲( M N U) 诱导的大鼠结肠等肿瘤生成的影响。方法: 雄性 S D 大鼠喂以用牛油、豆油、紫草油、玉米油和鱼油按不同比例调配,含脂肪量为15 % 的半合成饲料,分5 组。各组脂肪酸组成为:1 组以牛油为主富含饱和脂肪酸;2 组以豆油为主富含亚油酸,1 组和2 组基本不含有n 3 系列多不饱和脂肪酸;3 组以紫草油为主富含亚油酸,α和γ亚麻酸,n 6/n 3 脂肪酸之比为4 .53 ;4 组以鱼油为主富含n 3 系列多不饱和脂肪酸,n 6/n 3 脂肪酸之比为0 .73 ;5 组为混合油组,n 6/n 3 脂肪酸之比为1 .95 。对照组和实验组分别经腹腔注射磷酸盐生理盐水缓冲液和30 mg/kg .bw 的 M N U,每周一次,共6 次,喂养180 天。实验期控制了影响肿瘤产生的因素。结果:1 、2 和3 组产生的结肠肿瘤均显著高于4组( P< 0 .05) ,也相对高于5 组( P> 0 .05) ;1 、2 、3 和5 组产生的胃肿瘤也相对地高于4 组,但是,各组之间无显著的统计学差异。除了4 组和1 组外,其它各组在其它部位也产生了肿瘤。结论: M N U 能诱导喂以不同脂肪酸组成的大鼠产生以结肠癌为主的癌症;饲? 相似文献
9.
Ng TK 《Malaysian journal of nutrition》1995,1(1):21-30
An examination of the fat composition of the diet of a Malaysian urban hostel population obtained by chemical analysis of representative meals prepared by a 7-day rotation menu, revealed both nutritional attributes and limitations when compared against the dietary messages contained in the American Heart Association (AHA) and World Health Organisation (WHO) models. The Malaysian diet supplies 26% kcal i.e. 66 g total fat (51 g vegetable fats, 15 g animal fats) and contains <300 mg cholesterol, which are below the upper limits for these dietary constituents in the AHA and WHO models and conflicts with the perception that Malaysians in general, may be consuming too much fat and cholesterol. The supply of essential fatty acids (EFA), however, appears sub-optimal at 3.2% kcal mainly due to the comparatively low content of both the omega-6 (linoleic acid) and omega-3 [alpha-linolenic, eicosapentaenoate (EPA) and docosahexaenoate (DHA)] fatty acids in the Malaysian diet. The estimated omega-6/omega-3 fatty acid ratio of 10 further reflects an imbalance of these two families of polyunsaturated fatty acids (PUFA), which can be corrected to a ratio of 5 to 7 by moderate increases in the consumption of fish, soyabean-based foods, and pulses and nuts. Considering the current status of knowledge on the health effects of the different families of fatty acids, the ratio of 2:3:1 for the saturated fatty acids (SFA), monounsaturated fatty acids (MUFA) and PUFA in the diet is judged to improve fat intake and nutrition in Malaysians. Such a dietary fatty acids ratio can be satisfied by the use of a cooking oil containing 28% SFA, 53% MUFA, and 19% PUFA, which may obtained by the judicious blending of palm olein with MUFA-rich and PUFA-rich vegetable oils. Alternatively, moderate increases in the consumption of marine fish, pulses, nuts, soybean-based foods and their products would also serve the same end. 相似文献
10.
Effects of dietary fatty acids on the composition and oxidizability of low-density lipoprotein 总被引:5,自引:0,他引:5
Kratz M Cullen P Kannenberg F Kassner A Fobker M Abuja PM Assmann G Wahrburg U 《European journal of clinical nutrition》2002,56(1):72-81
OBJECTIVE: The objective of this study was to compare the effects of dietary monounsaturated fatty acids (MUFA), n-6 and n-3 polyunsaturated fatty acids (PUFA) on LDL composition and oxidizability. DESIGN, SETTING AND SUBJECTS: Sixty-nine healthy young volunteers, students at a nearby college, were included. Six subjects withdrew because of intercurrent illness and five withdrew because they were unable to comply with the dietary regimen. INTERVENTIONS: The participants received a 2-week wash-in diet rich in saturated fatty acids (SFA) followed by diets rich in refined olive oil, rapeseed oil or sunflower oil for 4 weeks. Intakes of vitamin E and other antioxidants did not differ significantly between the diets. RESULTS: At the end of the study, LDL oxidizability was lowest in the olive oil group (lag time: 72.6 min), intermediate in the rapeseed oil group (68.2 min) and highest in the sunflower oil group (60.4 min, P<0.05 for comparison of all three groups). Despite wide variations in SFA intake, the SFA content of LDL was not statistically different between the four diets (25.8-28.5% of LDL fatty acids). By contrast, the PUFA (43.5%-60.5% of LDL fatty acids) and MUFA content of LDL (13.7-29.1% of LDL fatty acids) showed a wider variability dependent on diet. CONCLUSIONS: Enrichment of LDL with MUFA reduces LDL susceptibility to oxidation. As seen on the rapeseed oil diet this effect is independent of a displacement of higher unsaturated fatty acids from LDL. Evidence from this diet also suggests that highly unsaturated n-3 fatty acids in moderate amounts do not increase LDL oxidizability when provided in the context of a diet rich in MUFA. 相似文献
11.
Fat content and fatty acid compositions of 34 marine water fish species from the Mediterranean Sea 总被引:2,自引:0,他引:2
Ozogul Y Ozogul F Ci˙çek E Polat A Kuley E 《International journal of food sciences and nutrition》2009,60(6):464-475
Fish is the best source of polyunsaturated fatty acids (PUFA), specifically n-3 fatty acids, especially eicosapentaenoic acid and docosahexaenoic acid. The objective of the present study was to determine the fat content and fatty acid compositions of 34 marine water fish species from the Mediterranean Sea. The fatty acid compositions of fish consisted of 30.10-46.88% saturated fatty acids, 11.83-38.17% monounsaturated fatty acids and 20.49-49.31% PUFA. In most species, the following fatty acids were identified: mystiric acid (C14:0, 0.72-8.09%), pentadecanoic acid (15:0, 0.05-2.35%), palmitic acid (C16:0, 15.97-31.04%), palmitoleic acid (C16:1, 1.48-19.61%), heptadecanoic acid (C17:0, 0.31-1.84%), cis-10-heptadecenoic acid (C17:1, 0.17-2.01%), stearic acid (C18:0, 2.79-11.20%), oleic acid (C18:1n9, 2.44-28.97%), linoleic acid (C18:2n-6, 0.06-3.48%), arachidonic acid (C20:4n-6, 0.12-10.72%), cis-5,8,11,14,17-eicosapentaenoic acid (C20:5n-3, 1.94-10%) and cis-4,7,10,13,16,19-docosahexaenoic acid (C22:6n-3, 3.31-31.03%). The proportions of n-3 PUFA ranged from 12.66% for annular seabream to 36.54% for European hake, whereas the proportions of PUFA n-6 were between 1.24% for oceanic puffer and 12.76% for flathead mullet. The results of this study show that these fish species were rich in n-3 PUFA, especially, eicosapentaenoic acid and docosahexaenoic acid. 相似文献
12.
Oosthuizen W van Graan A Kruger A Vorster HH 《The American journal of clinical nutrition》2006,83(5):1193-1198
BACKGROUND: Dietary fat intake in the South African population is increasing. This population also has a high prevalence of HIV infection. However, information about metabolic effects of dietary fatty acids on HIV-infected subjects is lacking. OBJECTIVE: Our objective was to investigate the relation between dietary fatty acid intake and liver function in HIV-infected compared with HIV-uninfected subjects. DESIGN: This cross-sectional epidemiologic survey included a representative sample of 1854 apparently healthy black volunteers aged > or =15 y, who were recruited from 37 randomly selected sites throughout the North West province of South Africa. Data from 216 asymptomatic HIV-infected and 1604 HIV-uninfected subjects were used. RESULTS: Intakes of polyunsaturated fatty acids (PUFAs), linoleic acid (n-6), and the ratio of PUFAs to saturated fatty acids (SFAs) were positively associated with all the liver enzymes measured in HIV-infected subjects (R = 0.16-0.65). Most of these R values differed significantly from the R values for HIV-uninfected subjects. No associations were seen between liver enzymes and intakes of SFAs and monounsaturated fatty acids. Vitamin E intake was positively associated with serum gamma-glutamyl transpeptidase (R = 0.23), alanine aminotransferase (R = 0.37), and aspartate aminotransferase (R = 0.58) in HIV-infected subjects; these correlations differed significantly from those of the HIV-uninfected subjects because PUFA sources are the main carriers of vitamin E. CONCLUSIONS: The results suggest that n-6 PUFA intakes may be related to liver damage in these HIV-infected asymptomatic subjects. The reasons or mechanisms responsible are not clear, and further research is necessary to determine the optimal safe amounts for intake of n-6 PUFAs by HIV-infected subjects, especially in countries with traditionally high intakes of n-6 PUFA-rich vegetable oils. 相似文献
13.
J. I. Harland 《Nutrition Bulletin》2009,34(2):174-184
There is a well‐established requirement for the UK population to reduce the saturates content of its diet from around 13.3% energy (E) intake to 10% E intake (including alcohol) and to improve fat quality by increasing monounsaturated fatty acid (MUFA) intake. Canola (rapeseed) oil is one of the richest sources of dietary MUFAs and is a good source of the omega‐3 polyunsaturated fatty acid (PUFA) alpha‐linolenic acid. Recent advances using conventional plant breeding have led to the development of high‐oleic canola, which has an increased level of MUFA and greater oxidative stability, making it suitable for a wide range of culinary purposes including frying. Around 7% of dietary saturated fatty acid (SFA) intake in adults derives from potatoes (fried potatoes and chips) and savoury snacks, with the value increasing to 13%–15% SFA in 4–18‐year‐olds. Traditionally, frying oils have been high in saturates content and their replacement with lower SFA alternatives provides the opportunity for food manufactures to lower SFA content of food with minimal consumer intervention. It has been estimated that at least half of the SFA in this category of foods can be replaced. In this review of literature, ten intervention studies were identified, where SFAs and/or carbohydrates were replaced by rapeseed oil, and the effect on blood lipids were reported. Results from these studies were pooled using standard meta‐analysis methods. The standard mean differences in total cholesterol (Total‐C) and low‐density lipoprotein cholesterol (LDL‐C) were 0.86 mmol/l [95% confidence interval (CI): ?1.05 to ?0.66] (ten studies) and 0.87 mmol/l (95% CI: ?1.07 to ?0.66) (nine studies), respectively, both significant (P < 0.0001) and non‐heterogeneous (P > 0.1). Using the pooled data, it can be calculated that each gram of SFA intake reduction was associated with reductions in both Total‐C and LDL‐C of 0.03 mmol/l, while each gram increase in either MUFA or PUFA reduced Total‐C by 0.05 and 0.09, respectively, and LDL‐C by 0.04 mmol/l and 0.08 mmol/l, respectively. It was also calculated that each 10 g increase in MUFA or rapeseed oil intake was associated with a reduction in Total‐C of 9.8% and 5.8%, respectively. In 2006, annual direct healthcare costs associated with coronary heart disease were estimated at £3.2 billion and the overall cost to the UK economy was nearly £9.0 billion. Assuming 3.5 g total fat (typically 30% E SFA) is replaced by 3.5 g rapeseed oil, then it can be predicted that Total‐C will be reduced by 1.9%, equivalent to an annual reduction of £61 million direct health costs and £171 million total costs. 相似文献
14.
Yoshida H Ikeda I Tomooka M Mawatari M Imaizumi K Seto A Tsuji H 《Journal of nutritional science and vitaminology》2001,47(3):242-247
Eicosapentaenoic and docosahexaenoic acids were distributed mainly in the sn-1 and 3 positions of seal oil triacylglycerols and in the sn-2 position of fish oil triacylglycerols. Seal oil-rich or fish oil-rich fats having constant polyunsaturated (PUFAs)/monounsaturated/saturated fatty acids and n-6/n-3 PUFAs ratios were fed to hamsters for 3 weeks. The control fat contained linoleic acid as the sole PUFA. The concentration of triacylglycerols in the liver was significantly lower in the fish oil group than in the control group. Phospholipid concentration in serum was lower and that in the liver was higher in the seal oil group compared with the fish oil group. The activities of fatty acid synthase (FAS), glucose-6-phosphate dehydrogenase (G6PDH), and the malic enzyme were significantly lower in both the fish and seal oil groups than in the control group. Dietary seal oil more effectively reduced arachidonic acid content in liver phosphatidylcholine and phosphatidylethanolamine and serum phosphatidylcholine than fish oil. These results showed that different intramolecular distribution of n-3 PUFAs influenced glycerolipid metabolism and arachidonic acid content in serum and liver phospholipids of hamsters. 相似文献
15.
L Masana M Camprubi P Sarda R Sola J Joven P R Turner 《The American journal of clinical nutrition》1991,53(4):886-889
The effects on plasma lipoproteins of four fat-modified diets were assessed in 11 nuns in a contemplative order in the Mediterranean region of Spain. Diet 1 [high polyunsaturated fatty acid (PUFA), low monounsaturated fatty acid (MUFA), low ratio of PUFAs to saturated fatty acids (P:S)] and diet 3 (low PUFA, high MUFA, low P:S) induced significant, directly comparable reductions in total plasma (12% and 13%, respectively) and low-density-lipoprotein (LDL) cholesterol (24% and 19%, respectively). Diet 2 [high PUFA, high MUFA, low saturated fatty acid (SFA), high P:S] induced greater decrements (23% and 30% in total plasma and LDL cholesterol, respectively). Diet 4 (low PUFA, low MUFA, high SFA, low P:S) induced a significant increase in LDL cholesterol of 11%. No significant changes in high-density-lipoprotein cholesterol were observed with these diets. Because the effects of PUFAs and MUFAs are comparable, no recommendations on modifying the habitual, high-MUFA-containing Mediterranean diet need be made other than, perhaps, a reduction in the overall intake of SFAs. 相似文献
16.
BACKGROUND: Animal products contribute significantly to the saturated fat and cholesterol content of the American diet. Contrary to dietary advice, consumers have not limited their consumption of animal products. Thus, an alternative approach might be to modify the fatty acid composition of animal products. OBJECTIVE: We tested the hypothesis that modified pork with a high content of polyunsaturated fatty acids (PUFAs) and a low content of saturated fatty acids (SFAs) would lower plasma LDL-cholesterol concentrations in women. DESIGN: Twenty women aged 19-24 y completed a crossover study with 2 diets. Nutritionally complete diets containing 42% of energy from fat differed only in the inclusion of either standard or modified pork. Venous blood samples were collected at weeks 0, 4, and 8. RESULTS: The diet containing modified pork significantly lowered total plasma (P < 0.0076) and LDL (P < 0.0382) cholesterol. The modified diet also resulted in an increase in the PUFA and a decrease in the SFA and monounsaturated fatty acid contents of the cholesteryl ester, free fatty acid, phospholipid, and triacylglycerol lipid classes in both plasma and erythrocytes. Plasma concentrations of glucose, insulin, triacylglycerol, and free fatty acids did not change significantly. CONCLUSIONS: Consumption of pork with a high PUFA content resulted in a decrease in the subjects' total plasma and LDL cholesterol and shifted the fatty acid composition from SFAs to PUFAs in the plasma and erythrocytes. Modification of the fatty acid composition of animal foods will be a useful approach to lowering the saturated fat consumption of Americans. 相似文献
17.
Fatty acid composition of mature human milk in Germany 总被引:14,自引:0,他引:14
An improved gas-chromatographic method with high resolution, sensitivity, and precision was used for analyzing the fatty acid composition of human milk lipids. In 24-h collections of mature hindmilk of 15 German women, 42 different fatty acids could be separated and quantified. Among the saturated fatty acids (median sum 42.76%, wt/wt), six odd-chain fatty acids accounted for 1.16%. Cis monounsaturated acids represented 37.98%. Trans fatty acids, which may have untoward effects on the recipient infant, contributed 4.40% with seven isomers. The polyunsaturated fatty acid (PUFA) fraction (13.82%) included 10 long-chain PUFAs (LCPs; 1.66%). The content of the physiologically important LCPs in milk lipids did not correlate with their parent fatty acids (ie, linoleic and alpha-linolenic acids) but there was a significant correlation between the sum of omega-3 and omega-6 LCPs suggesting interindividual differences in the capacity for secretion of milk-lipid LCPs between mothers. 相似文献
18.
19.
Yesım Özogul Fati˙h Özogul Erdoğan Çi˙çek Abdurrahman Polat Esmeray Kuley 《International journal of food sciences and nutrition》2013,64(6):464-475
Fish is the best source of polyunsaturated fatty acids (PUFA), specifically n-3 fatty acids, especially eicosapentaenoic acid and docosahexaenoic acid. The objective of the present study was to determine the fat content and fatty acid compositions of 34 marine water fish species from the Mediterranean Sea. The fatty acid compositions of fish consisted of 30.10–46.88% saturated fatty acids, 11.83–38.17% monounsaturated fatty acids and 20.49–49.31% PUFA. In most species, the following fatty acids were identified: mystiric acid (C14:0, 0.72–8.09%), pentadecanoic acid (15:0, 0.05–2.35%), palmitic acid (C16:0, 15.97–31.04%), palmitoleic acid (C16:1, 1.48–19.61%), heptadecanoic acid (C17:0, 0.31–1.84%), cis-10-heptadecenoic acid (C17:1, 0.17–2.01%), stearic acid (C18:0, 2.79–11.20%), oleic acid (C18:1n9, 2.44–28.97%), linoleic acid (C18:2n-6, 0.06–3.48%), arachidonic acid (C20:4n-6, 0.12–10.72%), cis-5,8,11,14,17-eicosapentaenoic acid (C20:5n-3, 1.94–10%) and cis-4,7,10,13,16,19-docosahexaenoic acid (C22:6n-3, 3.31–31.03%). The proportions of n-3 PUFA ranged from 12.66% for annular seabream to 36.54% for European hake, whereas the proportions of PUFA n-6 were between 1.24% for oceanic puffer and 12.76% for flathead mullet. The results of this study show that these fish species were rich in n-3 PUFA, especially, eicosapentaenoic acid and docosahexaenoic acid. 相似文献
20.
The relationships between the per person supply (expressed as percent of total energy supply) of saturated fatty acids (SFAs), monounsaturated fatty acids (MUFAs), and polyunsaturated fatty acids (PUFAs) obtained from 1979-1981 Food and Agriculture Organization (FAO) data, and the per person intake obtained from 52 individual dietary surveys performed in 19 countries, were examined. In particular, the ratio of PUFAs to SFAs (P:S) and the ratio of unsaturated fatty acids (MUFAs and PUFAs) to SFAs (U:S) obtained from both data sources were examined. Significant correlations (P less than 0.001) were found between the two data sources for the P:S, U:S, SFAs, and MUFAs and PUFAs (P less than 0.02) in 19 countries. It is concluded that the data on fat intake from the FAO are valid for use in epidemiologic studies. In view of the variability of the data, it is recommended to use them either expressed as percentage of energy or as ratios of the different components. 相似文献