腹腔镜在胃肠穿孔治疗中的应用(附23例报告)

目的：探讨腹腔镜下或腹腔镜辅助胃肠穿孔修补术的疗效。方法：对18例胃、十二指肠穿孔采用腹腔镜下全层缝合,加盖大网膜结扎固定;1例小肠穿孔在腹腔镜下双层缝合;3例小肠穿孔做腹壁小切口（2～3cm）,传统手术方法修补或切除病变肠管;1例乙状结肠穿孔行腹腔镜辅助下乙状结肠襻式造瘘。结果：18例胃、十二指肠穿孔及1例小肠穿孔在腹腔镜下完成修补术;3例小肠穿孔及1例乙状结肠穿孔在腹腔镜辅助下完成修复术。手术时间35～80min,平均50min。无并发症发生。23例随访6～24个月,平均18个月,18例胃、十二指肠穿孔术后6～8个月胃镜检查无溃疡复发,无肠梗阻等并发症发生。结论：腹腔镜治疗胃肠穿孔创伤小、恢复快、疗效满意。     

腹腔镜在医源性结肠穿孔治疗中的应用

目的探讨腹腔镜下修补医源性结肠穿孔的可行性和手术技巧。方法回顾性分析我院2007年10月至2009年12月期间腹腔镜下修补医源性结肠穿孔手术6例患者的临床资料,其中诊断性肠镜检查结肠穿孔2例,治疗性肠镜结肠穿孔4例。结果 6例患者均顺利完成腹腔镜下手术,无中转开腹。3例患者全腹腔镜下完成结肠穿孔修补,2例因破口较大在腹腔镜辅助下完成结肠穿孔修补,1例乙状结肠癌患者肠镜检查结肠穿孔后同时行腹腔镜下乙状结肠癌根治手术,术后未发生吻合口漏、残余感染等并发症。结论腹腔镜下修补医源性结肠穿孔安全、可靠,临床效果肯定。     

腹腔镜治疗胃十二指肠溃疡穿孔的应用体会(附16例报告)

目的 :探讨腹腔镜治疗胃十二指肠溃疡穿孔的应用价值。方法 :在腹腔镜监视下 ,吸尽腹腔内溢出的胃肠内容物后 ,行腹腔镜胃十二指肠溃疡穿孔修补术或腹腔镜辅助下的胃十二指肠溃疡穿孔修补术。结果 :手术均获成功 ,平均手术时间 90min ,3～5d进流质饮食 ,术后 5 ～7d出院 ,未发生并发症。结论 :腹腔镜胃十二指肠溃疡穿孔修补术具有患者痛苦小 ,损伤轻 ,康复快 ,脏器干扰小 ,腹腔冲洗方便、彻底等优点 ,值得临床推广应用。     

腹腔镜胃十二肠溃疡穿孔修补辅助H2受体拮抗剂治疗急性胃十二指肠溃疡穿孔

目的:总结腹腔镜下胃十二指肠溃疡穿孔修补术的临床经验。方法:回顾分析采用腹腔镜行胃十二指肠溃疡穿孔修补术的33例临床资料。结果:除1例十二指肠溃疡穿孔时间较长中转手术外,29例十二指肠球部穿孔和3例胃穿孔患者腹腔镜手术均获得成功,无并发症发生;术后辅助H2受体拮抗剂治疗,胃镜复查无复发。结论:腹腔镜修补并H2受体阻断剂口服治疗胃十二指肠溃疡急性穿孔的效果是肯定的,值得临床应用推广。     

腹腔镜下子宫穿孔修补术5例报告

目的 :探讨腹腔镜诊治子宫穿孔的价值。方法 :应用腹腔镜为 5例人工流产术后子宫穿孔患者进行探查并行穿孔修补术。结果 :5例患者均在腹腔镜下明确诊断 ,3例行完全腹腔镜下子宫穿孔修补术 ,2例行腹腔镜辅助下手术 ,患者均痊愈出院。结论 :腹腔镜手术患者创伤小 ,康复快 ,兼有诊断和治疗的功能 ,是诊治子宫穿孔的良好手段。     

腹腔镜胃十二指肠溃疡急性穿孔修补术后治疗效果分析

目的:探讨腹腔镜辅助下胃十二指肠溃疡急性穿孔修补术及术后疗效及安全性。方法:回顾性分析手术治疗的胃十二指肠溃疡急性穿孔58例患者的临床资料,根据患者手术方法不同分为腹腔镜组(32例)和开腹组(26例),腹腔镜组在腹腔镜辅助下行穿孔修补术,开腹组行开腹穿孔修补术,比较两组患者手术时间、切口长度、术后下床活动时间、术后镇痛药物应用、术后胃肠道功能恢复、术后并发症发生率。结果:腹腔镜组手术时间、切口长度、术后下床活动时间、术后镇痛药物应用情况均优于开腹组(P0.05);腹腔镜组术后肛门排气时间短于开腹组(P0.05),术后胃肠道不良反应发生率低于开腹组(P0.05);腹腔镜组术后并发症的发生率明显低于开腹组(P0.05)。结论:腹腔镜辅助下胃十二指肠溃疡急性穿孔修补术具有手术时间短、创伤性小、术后胃肠道功能恢复良好等优点,可作为胃十二指肠溃疡急性穿孔的首选治疗方案。     

腹腔镜下胃十二指肠穿孔修补术与开腹手术的对比

我们对 13例胃穿孔十二指肠穿孔患者行腹腔镜下修补术 ,并与 9例行传统开腹手术的患者比较 ,现介绍如下。资料与方法一、对象1.腹腔镜组 :对 2 0 0 0年 1月至 2 0 0 2年 6月间收治 13例胃十二指肠穿孔患者行腹腔镜下修补术 ,其中胃穿孔 5例 ,十二指肠穿孔 8例。本组患者年龄 2 8～ 4 7岁 ,平均 4 1 6岁 ,穿孔时间 4～ 10h ,平均 6 5h ,穿孔直径≤ 1 0cm ,术后病理学诊断均为上消化道溃疡穿孔。2 .开腹组 :对同期收治的 9例胃十二指肠穿孔患者行开腹手术 ,其中 4例为胃穿孔 ,5例为十二指肠穿孔。患者年龄32～ 4 8岁 ,平均 4 4 3岁 ,穿孔直…     

腹腔镜在25例消化道穿孔中的诊治体会

目的总结三年来25例消化道穿孔患者的腹腔镜诊断治疗的经验。方法对1例胃窦穿孔、15例十二指肠球部溃疡穿孔、2例外伤性小肠穿孔行探查修补术,7例急性阑尾炎穿孔行腹腔镜探查阑尾切除术．均获成功,其中有5例腹腔镜辅助下完成手术。结果25例消化道穿孔患者手术均获成功,无并发症发生。平均手术时间38min,于12-24h下床活动,平均住院时间4-9d：预后良好。结论腹腔镜技术在消化道穿孔既可探查明确诊断,同时进行治疗,手术视野开阔、便于清洗,创伤小手术时间短恢复快等优点。     

腹腔镜胃十二指肠溃疡穿孔修补术效果观察

目的观察腹腔镜胃、十二指肠溃疡穿孔修补术的效果。方法选取2014-01—2016-01间收治的50例胃十二指肠穿孔患者,均在全麻下行腹腔镜胃、十二指肠溃疡穿孔修补术。回顾性分析患者的临床资料。结果全组患者均成功完成腹腔镜穿孔修补术。手术时间30~140 min,平均60 min。术后住院时间6~14 d,平均8.8 d。均顺利康复出院并继续接受内科治疗。随访1~3 a,复查胃镜1例胃溃疡复发,实施胃大部切除术。其余患者溃疡愈合良好。结论腹腔镜下胃十二指肠穿孔修补术,创伤小、术后并发症少、患者恢复快、住院时间短、安全性高。术后应给予正规内科治疗,有利于防止溃疡复发。     

腹腔镜下胃十二指肠溃疡穿孔修补术效果观察

目的比较腹腔镜与开腹穿孔修补术治疗胃十二指肠溃疡穿孔的效果。方法根据不同手术方法将48例胃十二指肠溃疡穿孔患者分为2组,每组24例。观察组行腹腔镜下穿孔修补术,对照组行开腹穿孔修补术,比较2组的手术效果。结果观察组手术时间、术中出血量、术后镇痛药使用例数、患者下床活动时间、肛门排气时间、住院时间等指标均显著优于对照组,2组差异有统计学意义(P0.05)。结论与开腹穿孔修补术相比,腹腔镜下穿孔修补治疗胃十二指肠溃疡穿孔,创伤小、患者恢复快、安全,效果满意。     

有开腹手术史行腹腔镜胃肠手术的经验与技巧

目的:探讨有开腹手术史的患者行腹腔镜胃肠手术的可行性与技巧。方法:回顾分析8例有开腹手术史的患者再次行腹腔镜胃肠手术的临床资料。结果:除1例患者因腹腔广泛粘连中转开腹手术外,其余患者均在腹腔镜下完成粘连松解及相应的胃肠手术,无手术并发症发生。结论:有腹部手术史的患者仍可行腹腔镜胃肠手术,但应做好术前评估及中转开腹的准备。     

Single-layer suture to re-establish the digestive continuity following partial gastrectomy

We have introduced progressively since 1985 the single-layer continuous suture technique for gastroenteric anastomoses, since this technique has been proved to be safe in colonic anastomosis. From 117 gastrectomies performed between 1985 and 1988, 68 gastroenteric anastomoses were performed with the single-layer continuous suture technique (58%). In 1988 this technique has been applied to 92.5% of the gastroenteric anastomoses. The complication rate is low: 3% clinical leakage were found. We concluded that the single-layer continuous suture technique for gastroenteric anastomoses is safe, very simple and easy to perform. It is the logical extension to large and small bowel anastomoses that we have been doing, using this technique for over 4 years now with excellent results.     

三承气汤冲剂对实验动物胃肠功能影响的观察与比较

为了验证和比较三承气汤冲剂在腹部外科围手术期使用的效果,本实验用三承气汤冲剂分别从小鼠胃肠推进率和胃肠容积变化、家兔肠运动功能等几方面进行了观察比较。结果表明:三承气汤冲剂能显著增加实验动物的胃肠炭末推进率;大承气汤冲剂和调胃承气汤冲剂能显著增加实验动物的胃肠客积。三承气汤冲剂均能显著增加实验动物的肠蠕动和肠腔压力,但它们各自的特点是:大承气汤冲剂药效高,作用的时间长;加味小承气汤冲剂药效较小;调胃承气汤冲剂药效高但作用时间短。     

肠内、肠外营养对胃大部切除术后患者胃肠激素及胃动力的影响--前瞻性随机对照研究

目的比较肠内与肠外营养方式对胃大部切除术后患者胃肠激素及胃动力的影响,探究预测手术后发生胃瘫的敏感指标.方法将41例限期行胃大部切除术患者,随机分为肠内营养组（EN组,20例）与肠外营养组（PN组,21例）,术后分别给予肠内营养或肠外营养支持治疗,于术前、术后第1、7天清晨分别测定患者血清胃泌素（GAS）、血浆胃动素（MTL）、血浆胆囊收缩素（CCK）水平,术前、术后第7天行空腹胃电图（EGG）检查,并连续记录术后胃液引流量.结果（1）胃肠激素：EN组患者术后第7天MTL、胆囊收缩素水平明显高于PN组（P＜0.01）;两组患者GAS水平无明显差别.（2）胃动力：EGG提示EN组术后第7天胃电节律恢复情况明显优于PN组.结论（1）胃大部切除术严重干扰胃肠激素分泌以及正常胃电节律,抑制了胃蠕动.（2）胃大部切除术后应用肠内营养较肠外营养更有益于患者胃肠激素水平及胃动力功能指标的恢复.（3）胃肠激素（GAS、MTL、CCK）和EGG尚不宜作为预测手术后胃瘫发生的敏感指标.     

An animal model of pump-controlled gastroenteric feeding

A model for the study of gastroenteric feedings was established in guinea pigs. The model consists of guinea pig with gastrostomy tube and pump-controlled continuous enteral infusion system, with a swivel between the gastrostomy tube and pump system, so that the guinea-pig could move freely in the cage during the experimental period. We used this model for continuous gastroenteric feeding study lasting 2 weeks, and the mortality of animal was low. It is simple, easy to operate, inexpensive and suitable for the experiment of gastroenteric feeding.     

An unusual perforation of the colon: report of two cases

We herein present two cases of a colorectal perforation due to uncommon reasons. First, we treated a 45-year-old woman for a stercoral perforation of the sigmoid colon. The pathognomonic etiology was a barium fecaloma originating from an upper gastrointestinal series 9 months before admission. The second case was a 46-year-old woman who was admitted with a perforation of the transverse colon. She had experienced perforations of the sigmoid colon at 32 years of age and of the rectum at 44 years of age, respectively. The second and third conditions were diagnosed to be idiopathic, and were histologically proven by an abrupt obliteration and a thinness of the colonic wall with some infiltration of inflammatory cells. The first condition, however, was most likely a stercoral perforation. The postoperative course of these patients was uneventful, and both are doing well at this writing. Received: October 1, 2001 / Accepted: March 5, 2002     

Gastroenteric fistula complicating percutaneous endoscopic gastrostomy

Background

Gastroenteric fistula occurs in 2% to 3% of patients undergoing percutaneous endoscopic gastrostomy (PEG). The authors identified 12 children with this major complication.

Methods

A retrospective case note review was performed.

Results

Over a 5-year period, the complication rate for gastroenteric fistula was 3.5% (12 of 343 procedures). Presentation ranged from 1 day to 25 months post-PEG insertion. Eight patients presented with acute intestinal obstruction. The gastroenteric fistulous tract involved the posterior wall of the stomach in all cases. The plain abdominal x-ray was useful in establishing the diagnosis of the gastroenteric fistula.

Conclusions

Patients with gastroenteric fistula as a complication of PEG insertion can remain asymptomatic for prolonged periods. It often is difficult to make the diagnosis. A plain abdominal x-ray is a useful diagnostic modality.     

胃肠道腺癌P-糖蛋白和P53蛋白表达的关系

目的 探讨多药基因产物Ｐ糖蛋白（Ｐ－ｇｌｙｃｏｐｒｏｔｅｉｎ,Ｐ－ｇｐ）和Ｐ５３蛋白在胃肠道腺癌中协同表达的意义。方法 应用免疫组织化学方法检测术前未进行化疗的２５９例胃癌和１４０例结肠癌组织中的Ｐ－ｇｐ和Ｐ５３蛋白的表达。结果 Ｐ－ｇｐ和Ｐ５３在胃癌中的表达分别为２６．２５％（６８／２５９）和３７．０７％（９６／２５９）;在结肠癌在的表达分别为２３．５７％（３３／１４０）和４０％（５６／１４０）     

Laparoscopic enucleation of a gastroenteric duplication cyst arising in a pancreatic tail that did not communicate with the pancreatic duct: Report of a case

Gastroenteric duplication rarely occurs in locations such as the pancreas. We report a case of gastroenteric duplication of the pancreatic tail, which was noncontiguous with the stomach and had no communication with the pancreatic duct, in a 3-year-old girl. The cyst was enucleated by laparoscopy, without the need for pancreatic resection. The optimal treatment procedures vary considerably, depending on where the gastroenteric duplication is located in the pancreas and, most importantly, whether there is communication with the pancreatic duct.     

四君子汤加味对胃肠道手术后肠粘膜屏障功能的作用

目的:探讨中药四君子汤加味对胃肠道手术后病人肠粘膜屏障功能的保护作用及机理.方法:将40例胃肠道手术后病人随机分为对照组、肠内营养组和肠内营养加中药研究组.观察术前1 d、术后1 d和术后8 d的病人的营养指标(血清转铁蛋白、前白蛋白、视黄醇结合蛋白),免疫指标(IL-2、IL-6、sIL-2R),肠粘膜通透性指标(循环D-乳酸)的变化.结果:研究组病人术后8 d前白蛋白、视黄醇结合蛋白、IL-2等指标显著高于对照组和肠内营养组(P＜0.05),IL-6、sIL-2R、D-乳酸等指标显著低于对照组和肠内营养组(P＜0.05).结论:四君子汤加味可改善术后病人的营养状况,提高机体免疫机能,降低肠粘膜通透性,对肠粘膜屏障功能有明显的保护作用.