Osteitis condensans ilii: prevalence and characteristics of a neglected mimic of sacroiliitis

Clinical Rheumatology - Osteitis condensans ilii (OCI) is a benign condition characterised by triangular sclerosis of the iliac bone which may mimic radiographic sacroiliitis. Prevalence is...     

Osteitis condensans ilii in differential diagnosis of patients with chronic low back pain: a review of the literature

Osteitis condensans ilii (OCI) is a benign pathology causing chronic back and hip pain. Although the definitive cause is uncertain, mechanical stress is a significant factor in the development of the disease. Bilateral involvement of the sacroiliac joint is typical. We describe a case of unilateral OCI with unilateral sclerosis observed at radiography in a 34-year-old patient presenting with chronic back and hip pain, together with a review of the literature.     

Osteitis condensans ilii in differential diagnosis of patients with chronic low back pain: a review of the literature

Abstract

Osteitis condensans ilii (OCI) is a benign pathology causing chronic back and hip pain. Although the definitive cause is uncertain, mechanical stress is a significant factor in the development of the disease. Bilateral involvement of the sacroiliac joint is typical. We describe a case of unilateral OCI with unilateral sclerosis observed at radiography in a 34-year-old patient presenting with chronic back and hip pain, together with a review of the literature.     

Occurrence of bilateral sacroiliitis and ossification of anterior spinal ligaments in the same patient

 Enthesopathy and ligament calcification may occur in both the degenerative and inflammatory types of diffuse idiopathic skeletal hyperostosis and ankylosing spondylitis. Despite their fairly frequent occurence in rheumatic disease care settings, few reports of their presence in the same patient have appeared in the literature. In this report, we present the case of a male patient with chronic low back pain, who had both ossification of anterior spinal ligaments and bilateral sacroiliac joint ankylosis, and discuss the known pathogenesis of diffuse idiopathic skeletal hyperostosis. Received: September 17, 2001 / Accepted: January 31, 2002 Correspondence to: M. Bayramoğlu     

Sclerosis and hyperostosis of the manubrium sterni

Summary Seven females and one male with almost identical sclerotic and hyperostotic changes of the manubrium sterni are reported. The clinical course was prolonged and characterized by intermittent periods of exacerbation followed by improvement. Malignancies, bacterial inflammatory processes, and Paget disease, which were first suspected, could be excluded. Pustulosis-palmoplantaris was present in four patients and one had psoriasis vulgaris. None of the patients had sacroiliitis or peripheral joint changes, but the three youngest patients had sclerotic changes of other bones, including the lumbar spine, the pubic bone, and the clavicle. This may indicate that this is an adult disease analogous to chronic recurrent multifocal osteomyelitis, a disease mainly present in children and adolescents.     

Osteitis of the humerus following BCG vaccination

A 22-month-old Saudi child developed a granulomatous lesion of the left humerus following BCG vaccination in the overlying deltoid area 15 days after birth. The clinical picture, investigations and the histopathology reports are presented. The literature regarding BCG vaccine complications and their frequency is reviewed.     

Influence of more than six sternal fixation wires on the incidence of deep sternal wound infection

BACKGROUND: The aim of the present study was to examine the influence of the number of sternal fixation wires used on deep sternal wound infection rate and to analyze any possible interaction between this and local collagen-gentamicin prophylaxis evaluated in a previous trial. METHODS: The number of sternal fixation wires in all patients from one of two participating centers was counted. The patients were categorized according to six or fewer (standard technique, ST group) vs. seven or more wires (extra wires, XW group). RESULTS: The incidence of deep sternal wound infection was 4.2 % in the ST group and 0.4 % in the XW group ( P = 0.001). An analysis of the effect of local gentamicin, excluding the ST group from the analysis, showed an approximately 70 % reduction in sternal wound infection for all depths. CONCLUSION: This study supports the theory that additional fixation wires at the lower sternum actually reduce the incidence of deep wound infections. We suggest that a rigid sternal fixation is required to achieve the full benefit of local collagen-gentamicin prophylaxis.     

Osteitis Deformans (Paget’s Disease) and Calcific Disease of the Heart Valves

The prevalence of calcific aortic valve stenosis in Paget’s disease (osteitis deformans) was investigated by reviewing autopsy data of severe cases (≥75% involvement of ≥3 major bones, the femur, tibia, skull, and pelvis) and moderate cases (≥75% involvement of only 1 or 2 major bones) of Paget’s disease. Comparisons were made with normal age-matched controls. Aortic stenosis (AS) was present in 24% of 27 autopsies of severe Paget’s disease compared with 3.5% in 201 controls (p <0.01). Clinical signs of AS were present in 39% of 102 patients with severe Paget’s disease compared with 4% in 417 controls (p <0.101). The prevalence of AS in 18 cases of moderate Paget’s disease was similar to that of controls. Electrocardiograms were reviewed in 45 cases of Paget’s disease and compared with 80 controls of similar age. Complete atrioventricular (AV) block, incomplete AV block, bundle branch block, and left ventricular hypertrophy were present in 11%, 11%, 20%, and 13% of the Paget’s cases and in only 2.5%, 1.3%, 2.5%, and 3.8% in the control cases (p <0.05, <0.05, <0.01, and <0.05, respectively). It is concluded that in severe Paget’s disease there is a high prevalence of AS, heart block, and bundle branch block, but these are not present in moderate degrees of bone involvement.     

强直性脊柱炎棘上韧带组织病理学和超微结构观察

目的 观察强直性脊柱炎(AS)棘上韧带在脊柱骨性强直后发生的组织病理学及超微结构改变.方法 通过光镜下观察苏木素-伊红(HE)、苦味酸-天狼星红染色,并行电镜观察微观结构改变,与对照组进行比较.图像处理软件分析血管密度、胶原原纤维分布密度.采用t检验进行统计学分析.结果 实验组光镜下,胶原纤维排列紊乱,可见玻璃样变及脂肪浸润,大量血管增生,管径不一,有Ⅲ型胶原表达,电镜下胶原纤维分布稀疏,周期性横纹模糊,基质降解,可见基质小泡.对照组胶原纤维排列规则,无上述改变.实验组血管密度(6.8±0.7)/HP,对照组(1.0±0.4)/HP;实验组胶原原纤维分布密度(122±22)/μm2,对照组(218±10)/μm2,2组差异有统计学意义(P＜0.05).结论 棘上韧带在AS疾病进展过程中出现一系列的组织病理学改变.