Nasofacial reconstruction with calvarial bone grafts in compromised defects

Objectives/Hypothesis: To determine the utility of calvarial bone grafting in multiple reconstructive settings. In particular to examine the success of calvarial bone grafting of the nasofacial skeleton in a compromised wound bed. Study Design: Case series. Methods: A retrospective review was performed to identify patients undergoing calvarial bone graft reconstruction of the nasofacial skeleton. Patients were identified from operative records and the medical record was reviewed to identify age, gender, site of defect, indication for the operation, size of bone graft harvested, postoperative and delayed complications, radiation exposure, need for additional soft tissue, and graft loss. Results: Eighty-seven patients who underwent split calvarial bone grafts were identified and had a complete medical record available for review. Ninety grafts were harvested. Five subsites in the nasofacial skeleton were identified as sites for reconstruction. Forty cases were performed for revision of a previous complication, including 13 who had a previous alloplastic implant. Twenty-four additional cases were performed in a compromised wound bed and 64% of all cases were performed in either a revision or compromised setting. There was an 11% incidence of early postoperative complications, but there were no major complications at the donor site and only two major complications at the recipient site. Conclusion: Calvarial bone is a very useful material in the primary, revision, and compromised settings. This series suggests that split calvarial bone grafts is an adaptable, durable, and reliable material. It can be reliably used in the setting of radiation, infection, and inflammation.     

鼻整形术:歪鼻整形

歪鼻整形的内容涵盖了鼻的美学及功能。鼻上1/3偏曲的矫正多使用截骨术,鼻中间1/3偏曲通常使用鼻中隔矫正术修复。刻痕、切除、撑开移植物、自体组织撑开瓣等方法被用于矫正鼻背。鼻中隔尾侧偏曲通过刻痕、切除和在鼻前棘上重置鼻中隔来治疗。不同的截骨术用于不同类型的歪鼻畸形。治疗下鼻甲肥大和内鼻阈塌陷是纠正歪鼻气道功能受损的关键。鼻小柱支撑移植物、鼻尖缝合技术和鼻翼基底切除术用于修饰鼻尖和鼻翼。     

Manipulation of the fractured nose: a comparison of local infiltration anaesthesia and topical local anaesthesia

Reduction of simple nasal fractures under local anaesthetic is now an accepted practice. The anaesthetic is usually administered using an external percutaneous approach, coupled with topical intranasal cocaine. Topical local anaesthetic with intranasal cocaine is an alternative method. Fifty-four adult patients with simple displaced nasal fractures were randomised to three different groups prior to fracture reduction in the outpatient department. Group A received external local infiltration, Group B received topical EMLA cream whilst Group C received topical AMETOP gel. All patients received topical intranasal cocaine. The cosmetic result and airway patency were comparable in all groups. However, patients in group A perceived the procedure as significantly more painful than the patients of groups B and C. Despite the increased procedure time, we recommend topical anaesthesia as the method of choice to reduce simple nasal fractures in the outpatient department. It offers a similar outcome, whilst being significantly less painful than external infiltration.     

‘Moffett's’ solution: a review of the evidence and scientific basis for the topical preparation of the nose

General anaesthesia, often causes a widespread vasodilation, producing a hyperaemic nasal mucosa, hence the need for a topical application to decongest the nose and reduce the nasal blood flow to optimize the operative field. The use of a combination of cocaine, sodium bicarbonate and adrenaline given the eponymous title of ‘Moffett's Solution’ is standard practice in many rhinological procedures to provide local anaesthesia, vasoconstriction and decongestion. We discuss each component of ‘Moffett's’ reviewing the science and evidence behind its usage and the huge variation in the techniques of its application.     

Ossiculoplasty: autogenous bone grafts, 34 years experience

A series of 785 bone grafts between the tympanic membrane and head of the stapes were performed between 1964 and 1998. Ears were divided into ‘normal tympanic membrane’, ‘stage I’ and ‘stage II’ groups, in which the averages of the last postoperative air–bone gaps were 13.2, 18.7 and 18.1 dB, respectively (revision operations included). In the same order 43%, 26% and 23% of the ears showed air–bone gaps equal to or smaller than 10 dB; 85%, 61% and 67% equal to or smaller than 20 dB. Failures specific to the bone columella necessitated nine revision operations (eight for osseous fixation and one for atrophy). There have been no extrusions so far. Although, in the light of the literature the results are acceptable there is room for improvement.     

Early development of the nose in human embryos: a stereomicroscopic and histologic analysis

OBJECTIVES/HYPOTHESIS: To analyze the morphologic features of the nose in the human embryo from the 4th to 8th developmental week according to Carnegie stage. STUDY DESIGN: Stereomicroscopic and histologic analysis of the morphology of the human embryo. METHODS: A total of 27 cases of embryos, ranging from Carnegie stage 13 to 23, were analyzed. The external morphology was observed with a stereomicroscope, photographed, and analyzed. The histologic features were observed with a light microscope in the horizontally transected specimens stained with hematoxylin-eosin. RESULTS: The nasal placode was observed in stage 13, and it became flat or even concave in stage 14. In stage 15, the nasal pit was formed. In stage 16, the nasal sac and nasal fin were observed. In stage 17, the oronasal membrane was formed by thinning of the nasal fin. In stage 18, the primitive choana was established by a rupture of the oronasal membrane. In stage 19, the lateral palatine process projected vertically below the level of the tongue. The cartilaginous nasal capsule was formed in stage 20. In stage 21, the olfactory area was localized to the upper portion of the lateral nasal wall and the nasal septum. In stage 22, the lateral palatine process developed in a somewhat horizontal orientation. In stage 23, the premaxilla and primitive choana were formed. CONCLUSIONS: The development of the nose is most active from Carnegie stage 13 to 19, which corresponds to the end of the fourth embryonic week to the end of the seventh week. Thus, this period is considered to be the most important period in human nasal embryonic development.     

Anthropometric study of the caucasian nose in the city of Curitiba: relevance of population evaluation

Introduction

Norms and patterns of nasal esthetics are essential for an adequate preoperative evaluation and surgical programming. The esthetic nasal patterns used are a blend of artistic beauty ideals and tracings in models and celebrities. Because they do not consider population measures, they vary according to the period, and allow a discrepancy between the surgeon's preference and the patient's real desire for rhinoplasty. Not all populations wish to obtain an esthetic result according to these values, but prefer a natural result, that is, one with some of the nasal characteristics of the population to which they belong to. The Brazilian population lacks population studies to evaluate its nose measurements.

颞骨外伤并发脑脊液漏18例并文献复习

分析颞骨外伤并发脑脊液漏的临床特点,探讨其诊断及治疗策略。     

Melanoma of the nose: prognostic factors, three-dimensional histology, and surgical strategies

OBJECTIVES: The prominent position of the nose in the face accounts for its constant exposure to sunlight and thus its high incidence of malignant involvement. The aim of this prospective study was to define prognostic factors for nasal melanomas and to evaluate surgical strategies. METHODS: Forty-five patients with stage I/II melanoma were included. Malignant melanomas of the nose represented 0.8% of stage I/II cutaneous melanoma and 5.3% of head and neck melanoma (1983-2004). The median tumor thickness was 0.75 mm. Twenty-two of 33 Lentigo maligna melanomas (LMM) underwent three-dimensional (3D) histology in paraffin technique (i.e., micrographic surgery). RESULTS: The 5 year disease-specific survival rate was 96%, and the 5 year recurrence-free survival rate was 93%. There were no statistically significant risk factors in the univariate analysis. LMMs that were removed with accompanying 3D histology were thinner than other histologic types (median 0.75 vs. 1.55 mm). Compared with conventional histology, using 3D histology made it possible to reduce the excision margins (median 5 vs. 10 mm). There was one lymph node recurrence after LMM with 3D histology. Of five sentinel lymph node biopsies (SLNB) there was no positive SLNB and no recurrence. CONCLUSION: This is the largest study of nasal melanomas so far. Excision of LMM using 3D histology allowed the reduction of excision margins for better cosmesis and function. Our results do not permit conclusions regarding the prognostic impact of SLNB.     

Traumatic luxation of the nose in a newborn: case report and review of the literature

During delivery the delicate structures of the face are predominantly exposed to external force effects and hence deformities on the nose can emerge as a birth-related trauma in newborns. As self-straightening of the nasal septum commonly occurs, a conservative therapy is recommended for most cases. We report on a case where a birth-related trauma of the nose leaded to acute breathing problems in a newborn with insufficient oxygenation. An overview about the available literature is given. A cautious reposition of the nose proved to be an appropriate management for short- and long-term development. All authors contributed substantially to the paper in conception, design and writing.     

The anatomy of the lacrimal bone at the lateral wall of the nose: its significance to the lacrimal surgeon

The position, dimension and thickness of the exposed lacrimal bone at the lateral nasal wall in 10 cadaveric half-heads were examined. In all cases, the lacrimal bone at the lateral nasal wall was found to be just anterior to the mid-third of the uncinate process. The average length and width was 7.4 mm and 2.5 mm, respectively. In nine of the 10 half-heads, the lacrimal bone was very thin with an average thickness of 57 mm. In all the cases, the position of the lacrimal passage covered by the lacrimal bone corresponded to the postero-medial aspect of the upper lacrimal duct and the lower lacrimal sac. This study shows that the uncinate process is a reliable landmark for the lacrimal bone in endoscopic nasal surgery. The paper-thin lacrimal bone allows a bone rongeur to infracture through and nibble away the bony covering of the lacrimal sac in a dacryocystorhinostomy.     

Comparative study of chitosan/fibroin-hydroxyapatite and collagen membranes for guided bone regeneration in rat calvarial defects: micro-computed tomography analysis

This study aimed to utilize micro-computed tomography （micro-CT） analysis to compare new bone formation in rat calvarial defects using chitosan/fibroin-hydroxyapatite （CFB-HAP） or collagen （Bio-Gide） membranes. Fifty-four （54） rats were studied. A circular bony defect （8 mm diameter） was formed in the centre of the calvaria using a trephine bur. The CFB-HAP membrane was prepared by thermally induced phase separation. In the experimental group （n= 18）, the CFB-HAP membrane was used to cover the bony defect, and in the control group （n= 18）, a resorbable collagen membrane （Bio-Gide） was used. In the negative control group （n= 18）, no membrane was used. In each group, six animals were euthanized at 2, 4 and 8 weeks after surgery. The specimens were then analysed using micro-CT. There were significant differences in bone volume （BV） and bone mineral density （BMD） （P〈O.05） between the negative control group and the membrane groups. However, there were no significant differences between the CFB-HAP group and the collagen group. We concluded that the CFB-HAP membrane has significant potential as a guided bone regeneration （GBR） membrane.