Falls: A modifiable risk factor for the occurrence of hip fractures in the elderly

The objective of the study was to examine the clinical and demographic features of patients with hip fractures presenting to the Accident and Emergency Department, the University Hospital of the West Indies (UHWI). The study involved all patients with hip fractures registered in the Trauma Registry at the UHWI between January 1, 1998 and December 31, 2001. They were assessed retrospectively for age, gender, associated extrinsic and intrinsic factors, cause of the fall, location when fracture occurred and the site of the femur that was fractured. One hundred and fifty-two persons were identified There were one hundred and eleven women and forty-one men. Seventy-eight per cent of the falls occurred in the over sixty-five-year age group. Ninety per cent of the patients had a fall associated with their fracture. Most of the falls occurred at the patients' homes. This study indicated that falling at home was the commonest associated factor for the occurrence of hip fractures and preventive measures may lead to reductions in the frequency of hip fractures seen in the emergency room.     

营养支持预防老年髋部骨折术后低蛋白血症效果的Meta分析

目的 通过Meta分析评价营养支持对老年髋部骨折患者术后低蛋白血症的预防效果。方法 计算机检索关于营养支持预防老年髋部骨折患者术后低蛋白血症的随机对照临床试验(Randomized Controlled Trial,RCT),运用Rev Man 5.3软件对纳入文献进行Meta分析。结果 共纳入13篇文献,包括患者1520例,观察组768例,对照组752例。Meta分析结果显示:①主要结局指标:与常规饮食组相比,营养支持可提高髋部骨折患者术后血清白蛋白[MD=2.80,95%CI(1.59,4.01),P＜0.01]、血红蛋白[MD=6.11,95%CI(0.68,11.54),P＜0.05]、血清总蛋白[MD=6.33,95%CI(3.17,9.49),P＜0.01]、前白蛋白[MD=24.09,95%CI(3.05,45.14),P＜0.05];但不能提高转铁蛋白[MD=0.42,95%CI(-0.14,0.97),P＞0.05]。②次要结局指标:与常规饮食组相比,营养支持可提高髋部骨折患者术后营养指数、Harris髋关节评分、Barther指数、切口甲级愈合率,降低营养风险,减少住院时间,使患者下床时间提前;但不能减少术后并发症。结论 营养支持可预防髋部骨折术后低蛋白血症,其效果优于常规饮食。临床上应及早评估并努力纠正老年髋部骨折患者的营养不良。     

Efficacy of a hip protector to prevent hip fracture in nursing home residents: the HIP PRO randomized controlled trial

Context  Past studies of the efficacy of hip protectors to prevent hip fracture in nursing home residents have had conflicting results, possibly due to potential biases from clustered randomization designs and modest adherence to intervention. Objective  To determine whether an energy-absorbing and energy-dispersing hip protector would reduce the risk of hip fracture when worn by nursing home residents. Design, Setting, and Participants  Multicenter, randomized controlled clinical trial in which 37 nursing homes were randomly assigned to having residents wear a 1-sided hip protector on the left or right hip. Participants were 1042 nursing home residents (mean [SD] aged 85 [7] years; 79% women) who consented and adhered to the hip protector use during a 2-week run-in period and were enrolled. Participating facilities were in greater Boston, Massachusetts, St Louis, Missouri, and Baltimore, Maryland from October 2002 to October 2004. Mean duration of participation for nursing home residents was 7.8 months. None were withdrawn because of adverse effects. Intervention(s)  Undergarments with a 1-sided hip protector made of a 0.32-cm outer layer of polyethylene (2.7 kg/m³) backed by a hard high-density polyethylene shield (0.95 cm) that was backed by 0.9 kg/m³ of 1.27-kg ethylene vinyl acetate foam. Each facility was visited 3 times per week to assess adherence and provide staff support. Main Outcome Measure  Adjudicated hip fracture occurrences on padded vs unpadded hips. Results  After a 20-month follow-up (676 person-years of observation), the study was terminated due to a lack of efficacy. The incidence rate of hip fracture on protected vs unprotected hips did not differ (3.1%; 95% confidence interval [CI], 1.8%-4.4% vs 2.5%; 95% CI, 1.3%-3.7%; P = .70). For the 334 nursing home residents with greater than 80% adherence to hip protector use, the incidence rate of hip fracture on protected vs unprotected hips did not differ (5.3%; 95% CI, 2.6%-8.8% vs 3.5%; 95% CI, 1.3%-5.7%; P = .42). Overall adherence was 73.8%. Conclusions  In this clinical trial of an energy-absorbing/shunting hip protector conducted in US nursing homes, we were unable to detect a protective effect on the risk of hip fracture, despite good adherence to protocol. These results add to the increasing body of evidence that hip protectors, as currently designed, are not effective for preventing hip fracture among nursing home residents. Trial Registration  clinicaltrials.gov Identifier: NCT00058864      

The prevention of hip fracture with menatetrenone and risedronate plus calcium supplementation in elderly patients with Alzheimer disease: a randomized controlled trial

A high incidence of fractures, particularly of the hip, represents an important problem in patients with Alzheimer disease (AD), who are prone to falls and have osteoporosis. We previously found that vitamin K deficiency and low 25-hydroxyvitamin D (25-OHD) with compensatory hyperparathyroidism cause reduced bone mineral density (BMD) in female patients with AD. This may modifiable by intervention with menatetrenone (vitamin K2) and risedronate sodium; we address the possibility that treatment with menatetrenone, risedronate and calcium may reduce the incidence of nonvertebral fractures in elderly patients with AD. A total of 231 elderly patients with AD were randomly assigned to daily treatment with 45 mg of menatetrenone or a placebo combined with once weekly risedronate sodium, and followed up for 12 months. At baseline, patients of both groups showed high undercarboxylated osteocalcin (ucOC) and low 25-OHD insufficiency with compensatory hyperparathyroidism. During the study period, BMD in the treatment group increased by 5.7% and increased by 2.1% in the control group. Nonvertebral fractures occurred in 15 patients (10 hip fractures) in the control group and 5 patients (2 hip fractures) in the treatment group. The relative risk in the treatment group compared with the control group was 0.31 (95% confidence interval, 0.12-0.81). Elderly AD patients with hypovitaminosis K and D are at increased risk for hip fracture. The study medications were well tolerated with relatively few adverse events and effective in reducing the risk of a fracture in elderly patients with AD.     

老年髋部骨折病人手术耐受力及术后髋关节功能的影响因素分析

目的:探讨老年髋部骨折病人手术耐受力及影响术后髋关节功能的因素.方法 :选取119例股骨粗隆骨折病人作为研究对象,根据病人手术耐受力评价结果 分为手术组和非手术组.采用髋关节Harris评分评价手术组病人术后髋关节功能,并以病人术后髋关节功能评分作为因变量,以可能影响术后髋关节功能的因素作为自变量进行单因素和多因素logistic回归分析.结果:手术组病人手术耐受力评分为(78.6±12.2)分,明显优于非手术组的(61.8±10.1)分(P<0.01).单因素分析显示,高龄、骨折时间长、非稳定型骨折、复位质量满意度低、术后恢复不佳、术后有并发症、行髋关节置换术、术前有合并症和术前ASA分级高的病人髋关节功能评分较低(P<0.01).多因素logistic回归分析显示,高龄、骨折时间长、非稳定型骨折、复位质量满意度低、术后恢复不佳和术前有合并症均为影响病人术后髋关节功能的独立危险因素(P<0.05~P<0.01).结论 :髋部骨折手术前应对老年病人进行必要的手术耐受力综合评估,并针对术后影响髋关节功能恢复的相关危险因素进行及早干预.     

老年髋部骨折患者术后谵妄的危险因素分析及护理策略

目的 探讨老年髋部骨折患者术后谵妄的危险因素及护理对策。 方法 选择衢州市人民医院2016年1月—2018年9月间收治的74例老年髋部骨折术后谵妄的患者为谵妄组，198例老年髋部骨折术后未发生谵妄的患者为未谵妄组。对2组患者性别、既往谵妄病史、入院前使用抗精神病药物、助听器使用、骨折类型、术前准备不充分、吸入麻醉、手术时间、术后有无低氧血症、术后发生剧烈疼痛等情况进行统计，并采用单因素和多因素分析确定老年髋部骨折患者术后谵妄的危险因素。 结果 单因素显示既往谵妄病史、入院前使用抗精神病药物、助听器使用、骨折类型、术前准备不充分、吸入麻醉、手术时间长、术后有低氧血症、术后发生剧烈疼痛是老年髋部骨折患者术后谵妄的危险因素。多因素logistic回归分析结果显示:既往谵妄病史、入院前使用抗精神病药物、助听器使用、骨折类型、术前准备不充分、吸入麻醉、手术时间长、术后有低氧血症、术后发生剧烈疼痛是老年髋部骨折患者术后谵妄的独立危险因素。 结论 既往谵妄病史、入院前使用抗精神病药物、助听器使用、骨折类型、术前准备不充分、吸入麻醉、手术时间长、术后有低氧血症、术后发生剧烈疼痛是老年髋部骨折患者术后谵妄的危险因素，临床中要重视危险因素，做好治疗和护理，预防术后谵妄的发生。      

护理干预对预防老年髋部骨折患者术后深静脉血栓形成的影响

目的探讨护理干预对预防老年髋部骨折患者术后深静脉血栓形成的影响。方法选取我院2012年1月-2013年3月收治的98例老年髋部骨折患者,按照随机数字分组法将98例患者分为护理干预组和对照组各49例,对照组采用传统骨科护理方法,护理干预组在常规护理组的基础上予以系统护理干预。结果干预组DVT发生率为4.1%,显著低于对照组的26.5%,两组比较(P<0.05),差异具有统计学意义。干预组患者在疾病知识知晓、健康信念形成、健康行为执行方面显著优于对照组,两组比较(P<0.05),差异具有统计学意义。干预组平均住院时间显著短于对照组,差异亦具有统计学意义(P<0.05)。结论加强对老年髋部骨折患者进行围术期护理干预,有利于预防下肢深静脉血栓的形成,提升患者生活质量。     

SuperPATH微创全髋关节置换术治疗老年股骨颈骨折的短期疗效观察

目的观察SuperPATH微创全髋关节置换术治疗老年股骨颈骨折的短期临床疗效。方法选择40例Garden Ⅲ、Ⅳ型老年股骨颈骨折病人进行临床随机对照研究。按入院先后顺序,依次分入观察组和对照组。其中,观察组20例,采用SuperPATH微创全髋关节置换术;对照组20例,采用常规后外侧入路全髋关节置换术,比较2组短期临床疗效。结果2组病人术后6个月内均未发生脱位、假体周围骨折和感染等并发症。观察组的切口长度更短,术中出血量更少,且术后7 d、1个月和3个月髋关节Harris评分均高于对照组（P < 0.01）,2组在手术时间、术后髋关节影像学评价以及术后6个月髋关节Harris评分上差异无统计学意义（P>0.05）。结论SuperPATH微创全髋关节置换具有切口小,术中出血少,术后恢复快的优势,能够促进病人术后的快速康复。     

不同麻醉方法对髋部骨折老年患者术后转归的影响

目的：比较全身麻醉（general anesthesia, GA）和区域阻滞麻醉（regional anesthesia, RA）对接受手术治疗的髋部骨折老年患者术后心肺并发症和住院期间死亡率的影响。方法：回顾性分析我院骨科2005年1月至2014年12月间收治的572例髋部骨折老年患者的临床资料,分别记录患者性别、年龄、术前内科合并症、术前卧床时间、骨折原因、手术和麻醉方法、术后心肺并发症以及住院期间的死亡率。应用多重Logistic回归模型分析不同麻醉方法对髋部骨折老年患者术后住院死亡率的影响。结果：8例老年患者发生住院期间死亡（8/572,死亡率1.4%）,其中RA组5例（5/392,死亡率1.3%）,GA组3例（3/180,死亡率1.7%）,两组患者间住院死亡率的差异无统计学意义（P>0.05）,多重Logistic回归分析显示,性别（OR=0.18,95% CI：0.03~1.05,P=0.057）、年龄（OR=1.22,95% CI：1.07~1.38,P=0.002）、术前肺部合并症（OR=12.09,95% CI：2.28~64.12,P=0.003）和手术方式（OR=9.36,95% CI：1.34~64.26,P=0.024）是术后发生住院期间死亡的独立危险因素。36例患者术后发生心血管系统并发症（36/572,发生率6.3%）,其中RA组19例（19/392,发生率4.8%）,GA组17例（17/180,发生率9.4%）, 多重Logistic回归分析显示,年龄（OR=1.13,95% CI：1.07~1.19,P<0.001）、高血压（OR=2.72,95% CI：1.24~5.96,P=0.012）和术前脑血管合并症（OR=2.11,95% CI：0.99~4.52,P=0.054）是发生术后心血管系统并发症的独立危险因素。56例患者术后发生呼吸系统并发症（56/572,发生率9.8%）,其中RA组19例（19/392,发生率4.8%）,GA组37例（37/180,发生率20.6%）,多重Logistic回归分析显示,年龄（OR=1.13,95% CI：1.07~1.19,P<0.001）、术前肺部合并症（OR=2.89,95% CI：1.28~7.05,P=0.020）、术前卧床时间（OR=1.11,95% CI：1.04~1.18,P=0.003）和麻醉方法（OR=5.86,95% CI：2.98~11.53,P<0.001）是术后发生呼吸系统并发症的独立危险因素。结论：RA和GA对接受手术治疗的髋部骨折老年患者住院期间死亡率无显著影响,但RA组患者术后呼吸系统并发症的发生率低于GA组患者。     

高龄髋部骨折患者肺部并发症的回顾性研究

目的:探讨高龄髋部骨折患者出现肺部并发症的特点及预防措施。方法：回顾性研究我院符合标准的237例高龄髋部骨折患者的病例资料,分析呼吸系统基础疾病、不同年龄组、手术干预、治疗方法等相关因素与出现肺部并发症的关系。结果：237例患者在治疗过程中79例出现肺部并发症(约占33.33%)；不同年龄组出现肺部并发症之间的比较有统计学意义(P =0.018)；手术干预前后患者肺部并发症比较差异无统计学意义(P =0.174)；保守治疗组与手术治疗组出现肺部并发症的比较有统计学意义(P =0.010)。结论：高龄髋部骨折患者在治疗过程中容易并发肺部并发症,认为高龄、呼吸系统基础疾病及保守治疗是引发肺部并发症的高危因素。     

同侧股骨干骨折合并髋部损伤13例

目的 探讨同侧股骨干骨折合并髋部损伤的临床特点和诊治要点。方法 对1999年3月至2003年2月收治的13例合并同侧髋部损伤的股骨干骨折进行回顾性研究,包括髋部损伤类型、早期诊断情况、治疗方法选择等。结果 7例股骨干骨折发生在中1／3,所有股骨颈骨折均发生在基底部,而粗隆部骨折类型无明显规律。11例股骨干骨折和9例髋部骨折行手术治疗。所有患者随访10～25个月,骨折均顺利愈合,未发现有股骨头缺血坏死表现。结论 高能量所致股骨干骨折患者应常规拍摄高质量骨盆前后位X线片。股骨重建髓内钉治疗股骨干骨折合并同侧髋部损伤是一种较理想方法,能同时稳定股骨干和髋部骨折,且较少破坏骨折部位血运,有利骨折愈合。     

HMG-CoA reductase inhibitors and the risk of hip fractures in elderly patients

CONTEXT: Recent animal studies have found that 3-hydroxy-3-methylglutaryl coenzyme A (HMG-CoA) lipid-lowering drugs (statins) substantially increase bone formation, but whether statin use in humans results in clinically meaningful bone formation or a reduction in the risk of osteoporotic fractures is not known. OBJECTIVE: To determine whether the use of statins is associated with reduced hip fracture risk. DESIGN: Case-control study. SETTING AND PATIENTS: A total of 6110 New Jersey residents aged 65 years or older and enrolled in Medicare and either Medicaid or the Pharmacy Assistance for the Aged and Disabled program. Case patients (n=1222) underwent surgical repair of a hip fracture in 1994. Control patients (n=4888) were identified at a ratio of 4:1 and frequency-matched to case patients for age and sex. MAIN OUTCOME MEASURE: Adjusted odds ratio (OR) of hip fracture by statin use in the 180 days and 3 years prior to the index date (the earliest date of admission for surgery), adjusted for demographic and clinical characteristics and health care utilization. RESULTS: Use of statins in either the prior 180 days (adjusted OR, 0.50; 95% confidence interval [CI], 0.33-0.76) or prior 3 years (adjusted OR, 0.57; 95% CI, 0.40-0.82) was associated with a significant reduction in the risk of hip fracture, even after controlling for variables such as race, insurance status, psychoactive medications, estrogen and thiazide use, ischemic heart disease, cancer, and diabetes mellitus. No significant relationship was observed between use of nonstatin lipid-lowering agents and hip fracture risk. Clear relationships were observed between the degree of reduction in hip fracture risk and the extent of statin use; there was no evidence of such relationships with nonstatin lipid-lowering agents. After adjusting for extent of statin use in the prior 3 years, current use (on the index date) was associated with a 71% reduction in risk (adjusted OR, 0.29; 95% CI, 0.10-0.81). The relationship between statin use and hip fracture risk persisted after controlling for variables such as the number of medications, the Charlson comorbidity index score, and hospitalization or nursing home stay in the last 180 days, as well as after excluding patients who were in a nursing home prior to their index date or who died in the year after their index date. Use of nonstatin lipid-lowering agents was not observed to be associated with reduction in hip fracture risk in any of these alternative models or analyses. CONCLUSIONS: These findings support an association between statin use by elderly patients and reduction in the risk of hip fracture. Controlled trials are needed to exclude the possibility of unmeasured confounders. JAMA. 2000;283:3211-3216     

护理干预对预防老年髋部骨折术后深静脉血栓形成的影响

目的:分析护理干预对预防老年髋部骨折患者术后深静脉血栓形成的影响。方法:将108例老年髋部骨折手术患者随机分为干预组和对照组,每组54例,对照组给予常规术后药物治疗和护理,干预组在此基础上,加强围术期护理干预,并比较两种护理模式的护理效果。结果:干预组术后深静脉血栓发生率为3.71%,显著低于对照组的14.81%,差异具有统计学意义(P<0.05);干预组平均住院时间为(1.79±0.19)d,显著短于对照组的(2.98±0.32)d,差异亦具有统计学意义(P<0.05);干预组对疾病知识知晓率、遵医用药、坚持功能锻炼等健康行为执行情况均显著优于对照组(P<0.05)。结论:加强对老年髋部骨折患者进行围术期护理干预,有利于预防下肢深静脉血栓的形成,提升患者生活质量。     

锁定钢板与动力髋螺钉治疗老年股骨转子间骨折患者的疗效比较

目的比较锁定钢板与动力髋螺钉治疗老年患者股骨转子间骨折的疗效,旨在为临床治疗老年患者股骨转子间骨折提供指导依据。方法将2009年1月～2011年1月我院住院的28例锁定钢板治疗的老年股骨转子间骨折患者设立为A组,另选择同期行动力髋螺钉治疗的老年股骨转子间骨折患者28例设立为B组,比较两组患者的手术时间、术中出血量、住院时间、髋关节功能及并发症等。结果①A组患者手术时间长于B组、术中出血量多余B组,差异有统计学意义(P<0.05或P<0.01)。但A组术后住院时间与B组比较,差异无统计学意义(P>0.05)。②两组患者均随访1年,A组患者术后髋关节功能Harris评分显示,其优良率明显高于B组,差异有统计学意义(P<0.05)。③A组患者术后发生并发症2例(7.2%),B组患者术后发生并发症8例(28.6%),两组患者术后并发症发生率比较,差异有统计学意义(P<0.05)。结论锁定钢板与动力髋螺钉治疗老年股骨转子间骨折患者各具优缺点,临床医生应根据患者情况选择合适的内固定方式,从而发挥其优势。     

127例高龄髋部骨折的治疗体会

目的总结高龄（≥70岁）髋部骨折的治疗体会。方法 127例高龄（≥70岁）髋部骨折患者均采用手术治疗,并对其临床资料及治疗效果进行回顾性分析。结果无术中术后死亡,术后发生并发症12例,发生率为9.45%。术后随访9～36个月,参照Harris髋关节功能评价标准,股骨颈骨折术后得分为55～90分,平均79.36分;粗隆间骨折术后得分为65～93分,平均85.57分。1例行髋翻修手术。所有病人均未出现骨不连及髋内翻畸形。结论恰当的围手术期准备,正确的手术方式、麻醉的选择以及积极的术后并发症预防,是手术治疗高龄老年人髋部骨折成功的关键。     

股骨颈轴长及内侧偏距对髋部骨质疏松性骨折的影响

目的分析髋部骨质疏松性骨折患者股骨颈轴长及内侧偏距变化对骨折危险性的影响。方法选取2010年6月至2011年3月南华大学附属第一医院55岁以上骨质疏松症患者90例,其中髋部新鲜骨质疏松性骨折组42例,对照组48例,利用法国Osteocore 3双能X线骨密度仪配置的高级骨科专用分析测量工具包,测量股骨颈轴长和内侧偏距,进行统计学分析,比较各组间的差异。结果骨折组中股骨颈轴长和内侧偏距均增大(P<0.05),与对照组的差异具有统计学意义。结论髋部骨质疏松性骨折患者股骨颈轴长和内侧偏距的变化,使骨骼负荷增加,是影响骨折发生的重要因素。     

髋部骨折流行病学分布特点:单中心2 859例分析

目的 回顾性分析2 859例髋部骨折患者的流行病学特点,为进一步完善老年髋部骨折的防治手段提供依据.方法 收集第二军医大学长海医院2004年1月-2016年12月收治入院的所有髋部骨折患者病例资料,采集患者的年龄、性别、受伤机制、骨折类型、受伤至手术时间、住院时间、出血量、手术方法等信息,采用SPSS 16.0软件进行数据处理,分析髋部骨折的流行病学分布特点.结果 (1)本院的髋部骨折收治总数逐年增加,其中股骨颈骨折的占比最高(1 602/2 859,56.03％),股骨粗隆间骨折次之.(2)髋部骨折患者年龄52～104岁,年龄分布差异有统计学意义(P＜0.05).其中,71～80岁组最多,占37.39％(1 069/2 859).(3)髋部骨折病例中女性所占比例(1 916/2 859,67.02％)高于男性(943/2 859,32.98％).(4)受伤机制分布差异有统计学意义(P＜0.05),行走中自行摔伤导致骨折最多,占87.65％(2 506/2 859).(5)骨折类型在不同性别之间的分布差异具有统计学意义(P＜0.05),女性股骨颈骨折较多,男性股骨粗隆间骨折比例较高.(6)所有患者中合并有糖尿病(765/2 859,26.76％)或心脑血管疾病(739/2 859,25.85％)的病例数最多.结论 老年髋部骨折以股骨颈骨折和股骨粗隆间骨折多见,其在年龄、性别、受伤机制、合并症等方面均有一定的流行病学分布特征,这为进一步改善髋部骨折的防治策略提供了线索.     

人工全髋关节置换术治疗老年患者股骨颈骨折18例临床疗效观察

目的评价应用人工全髋关节置换术治疗老年患者股骨颈骨折的临床疗效。方法采用人工全髋关节假体手术治疗老年患者股骨颈骨折患者18例,回顾性分析（2003-12～2011-12）应用人工全髋关节置换术治疗老年患者18例的临床资料。结果本组18例术后下床时间7～9 d。骨折复位满意,随访9～18个月,无假体松动、下沉、断裂。髋关节功能按Harris评分,优良率88.9%。结论采用人工髋关节置换术治疗老年患者股骨颈骨折创伤小,卧床时间短,可早期离床活动,减少并发症,有利于关节功能恢复,提高老年患者术后生活质量。     

老年人髋部骨折相关因素的观察

目的　观察老年人髋部骨折的骨密度 (BMD)值 ,探讨老年人股骨颈骨折和转子间骨折与骨密度的相关性。方法　将5 16例老年髋部骨折住院患者按年龄、性别及骨折类型分组 ,选择性行骨密度检查 ,对检查结果进行统计学处理 ,并对临床髋部骨折患者分布情况进行分析。结果　骨折组的骨密度值均低于同性别正常人骨峰值的 2 .5s;同性别、同年龄组股骨颈骨折和转子间骨折患者的骨密度间差异无显著性 (P >0 .0 5 ) ;老年人髋部骨折主要集中在 6 0～ 79岁之间 ,占同期髋部骨折的74 %。结论　老年人骨量低于同性别骨峰值应视为髋部骨折的危险人群。骨量降低是老年人髋部骨折的前提条件 ,但老年骨质疏松患者发生股骨颈骨折或发生转子间骨折 ,主要决定于受伤时的暴力大小和方向。     

高龄老年髋部骨折患者术前下肢深静脉血栓形成的危险因素

目的 研究高龄老年髋部骨折患者术前下肢深静脉血栓（deep vein thrombosis,DVT）形成的危险因素。方法 回顾性研究2018年3月至2019年2月北京积水潭医院老年创伤骨科病房收治的687例80岁以上的高龄老年髋部骨折患者。通过多普勒超声对下肢DVT进行初筛,可疑或阳性的患者行静脉造影确诊DVT。通过单因素和多因素逐步Logistic回归分析,探讨术前下肢DVT的独立危险因素。结果 高龄老年髋部骨折术前下肢DVT发生率为12.4%（85/687）。经过多因素逐步Logistic回归分析得出受伤至入院时间、活化部分凝血活酶时间（activated partial thromboplastin time,APTT）、股骨粗隆间骨折是高龄老年髋部骨折术前下肢DVT的独立预测因子（P<0.05）。结论 高龄老年髋部骨折患者术前下肢DVT的发生率高,股骨粗隆间骨折、骨折后延迟入院以及APTT缩短的患者术前下肢DVT的发生率增加,对有这些危险因素的患者应采取预防措施,以降低术前DVT的发生率。