冠心病心导纳环检测指标与心电图结果分析

目的 探讨心导纳环(ADL)检测方法对冠心病诊断及心功能评定作用。方法 本文检测并分析96例冠心病患者及73例正常人ADL和心电图(ECG)。结果 冠心病组SV、CO、CI、EF、LVET、C、LI、ADLe及ADL_1均低于正常对照组,二组比较差异非常显著(P<0.01);TPR、PEP及PEP/LVET均高于正常对照组,二组比较差异非常显著(P<0.01)。两种方法比,ADL阳性检出率为89.58％,ECG阳性检出率为72.92％,前者明显高于后者。结论 冠心病患者存在着不同程度的心肌损伤;ADL异常改变对冠心病的早期诊断及心功能判定优于ECG;ADL无创检测方法有一定的临床应用价值。     

心导纳微分环检测冠脉供血不足的实验研究

目的探讨心导纳微分环(ADL)与大动物血流量间的内在联系,观察控制冠状动脉流量造成ADL形态改变与常规心电图的关系.方法检测37只犬ADL面积与电磁流量计(EFM)测定主动脉通过量(SV)及与心导管法测定左心室压力-容积环(P-V环)对照分析.结果ADL射血相面积与EFM所测得的SV间相关系数r=0.929;ADL总面积与PV环面积相关系数r=0.925.结论ADL面积与大动物血流量间存在着密切的内在联系;在改变心脏前、后负荷及心脏收缩力时,ADL可较灵敏发生有规律的相应变化;且ADLI相离心支与归心支形态的改变可间接反映冠状动脉供血状态,比常规心电图检测更敏感.     

心导纳微分环与冠状动脉狭窄的初步探讨

目的 探讨心导纳微分环(ADL)快速射血相(ADL1)环体切迹与冠状动脉狭窄的关系。方法对照分析了44例临床诊断冠心病患的冠状动脉造影(CAG)结果及ADL1环体形态改变情况。结果诊断性试验评价ADL1环体切、迹诊断冠状动脉狭窄灵敏度为94．3%,特异度为66．7%,准确度为88．6％．阳性似然比为2．83,阴性似然比为0．09。结论心导纳微分环快速射血相离心支切迹与冠状动脉狭窄密切相关,且较心电图敏感。     

双通道阻抗／导纳仪与心阻抗环检测系统

该双通道阻抗/导纳仪采用三对点状胸部导联电极,从两个不同方向测取心阻抗信号变化而没有恒流源电场的相互干扰。检测信号包括△Z_X、△Z_Y、△Z_Z和dZ_X/dt dZ_Y/dt、dZ_Z/dt。同时采集的两信号送入计算机合成阻抗环。20名正常人检测和计算表明△Z内的环面积小(A<4.6×10 ~(-3)Ω~2),无明确形状(b/a<0.34):dZ内的环类似(b/a<0.4);但是△Z与dZ交叉合成的环具有较大面积和确定的形状(b/a>0.45)。     

心导纳环观察工业噪声对心血管功能的影响

用心导纳环观察工业噪声对工人心血管功能的影响 ,其主要表现为环体运行不光滑、射血相切迹等 ,表明其心肌收缩协调性下降     

心导纳微分环检测冠脉供血不足的实验研究

目的 探讨心导纳微分环(ADL)与大动物血流量间的内在联系,观察控制冠状动脉流量造成ADL形态改变与常规心电图的关系。方法 检测37只犬ADL面积与电磁流量计(EFM)测定主动脉通过量(SV)及与心导管法测定左心室压力-容积环(P-V环)对照分析。结果 ADL射血相面积与EFM所测得的SV间相关系数r=0．929;ADL总面积与P-V环面积相关系数r=0．925。结论 ADL面积与大动物血流量间存在着密切的内在联系;在改变心脏前、后负荷及心脏收缩力时,ADL可较灵敏发生有规律的相应变化;且ADLI相离心支与归心支形态的改变可间接反映冠状动脉供血状态,比常规心电图检测更敏感。     

心导纳微分环与冠状动脉狭窄的初步探讨

目的探讨心导纳微分环(ADL)快速射血相(ADL1)环体切迹与冠状动脉狭窄的关系.方法对照分析了44例临床诊断冠心病患者的冠状动脉造影(CAG)结果及ADL1环体形态改变情况.结果诊断性试验评价ADL 1环体切迹诊断冠状动脉狭窄灵敏度为94.3%,特异度为66.7%,准确度为88.6%,阳性似然比为2.83,阴性似然比为0.09.结论心导纳微分环快速射血相离心支切迹与冠状动脉狭窄密切相关,且较心电图敏感.     

导纳血液循环自动检测仪检测结果的数据处理

利用HD-3181型导纳血液循环自动检测仪分别对心肌缺血前、后的家兔进行采集，为使采集到的导纳微分环波形数据进行量化分析，本文介绍了使用计算机技术定位导纳微分图上的特征点，并按时相将形成导纳微分环的导纳、导纳微分原始数据，以及各项参数的计算结果输出到数据文件中，对导纳微分环数据进行更深入的研究，为临床更好地应用导纳微分环技术提供理论依据。     

脑导纳微分环研究初探

利用脑血流自动检测仪 ,对正、异常两组人群采样 ,提取参数 ,并进行t检验。     

共用通道心阻抗／导纳图微机检测系统

共用通道心阻抗／导纳图微机检测系统泰安市医学仪器研究所李兰玉，杨继鹏，陈兆涛心阻抗图（ＩｍｐｅｄａｃｅＣａｒｄｉｏｇｒａｐｈ，ＩＣＧ）是一种利用心动周期引起的胸部阻抗的微小瞬时变化经放大记录而得到的曲线。自１９６６年Ｋｕｂｉｃｅｋ利用其测定排血量以来...     

冠心病基因检测与冠心病的关联性

目的观察冠心病基因检测与冠心病是否有关联性,以及关联程度如何。方法选取120例住院患者,其中60例为冠心病人,60例为非冠心病人。年龄40—65岁。冠心病为观察A组,非冠心病为对照B组,记录性别、年龄、冠心病家族史、高血压史、糖尿病史,并均抽血行冠心病基因检测。A组选1人和B组选1人按年龄相近、性别相同配对,共形成60对。开始进行1：1条件Logistic回归分析。结果冠心病家族史、高血压史、糖尿病史、以及冠心病基因检测与冠心病均有关联性。其中冠心病基因检测与冠心病的关联程度低于其他3个因素。结论冠心病基因检测与冠心病有关联性。     

老年冠心病患者感染性指标水平变化的临床研究

目的监测门诊治疗的老年冠心病患者感染性指标水平变化,探讨其临床应用价值,提高临床对老年冠心病患者的认识及治疗水平。方法选取门诊治疗的老年冠心病患者118例作为观察组,其中急性心梗死(AMI)患者39例,不稳定心绞痛(UAP)患者79例,另外选取同期健康体检者110名作为对照组;观察组患者在初诊时及门诊治疗3个月后,对照组人员于体检当天抽取清晨静脉血,分别通过增强比浊法测定和酶联免疫吸附法测定其高敏C-反应蛋白(Hs-CRP)、白介素-6(IL-6)、IL-8、IL-18、IL-20水平。结果观察组患者治疗前Hs-CRP(6.81±1.43)mg/L、IL-6(65.73±5.21)ng/L、IL-8(93.16±13.27)ng/L、IL-18(123.75±23.96)ng/L、IL-20(58.17±11.75)ng/L,治疗后分别为(3.22±1.05)mg/L、(31.36±2.99)ng/L、(74.22±11.46)ng/L、(62.28±10.35)ng/L、(33.96±7.48)ng/L,经过治疗,观察组患者上述指标较治疗前均明显下降,但仍明显高于对照组;AMI及UAP患者Hs-CRP、IL-6、IL-8、IL-18、IL-20水平均较治疗前有所降低,但AMI患者无论是治疗前还是治疗后,上述指标水平均明显低于UAP患者,差异有统计学意义(P<0.05)。结论对门诊老年冠心病患者上述感染性指标水平进行检测,可以对患者的病情有所判断,从而指导治疗方案的确定。     

基于中国双生子人群的冠心病遗传-BMI交互作用研究

目的:分析冠心病患病的遗传-BMI交互作用。方法:利用中国双生子登记系统募集的20 340对≥25岁的同性别双生子,构建单变量遗传-环境交互作用模型,通过评估BMI对冠心病遗传效应的修饰作用反映冠心病的遗传-BMI交互作用。结果:调整年龄后,在男性中发现BMI对冠心病患病受到的遗传效应有负向修饰作用,遗传效应修饰系数（...     

Glycemic index and heart disease

A diet high in carbohydrates with high glycemic indexes (GI) and glycemic load were linked to risk of coronary heart disease development in women in a large prospective study. Two cross-sectional studies showed that low-GI diets are associated with high HDL-cholesterol concentrations, especially in women. In a tightly controlled study of patients with type 2 diabetes, serum total cholesterol, LDL cholesterol, and apolipoprotein B concentrations fell more significantly after a low-GI diet than after a high-GI diet. In the same study, plasminogen activator inhibitor-1 concentrations were reduced by 58% after the low-GI diet. Insulin-stimulated glucose uptake by adipocytes was significantly higher in patients undergoing coronary artery bypass graft surgery after 4 wk of consuming a low-GI diet than after consuming a high-GI diet. The effects of low-GI diets may be mediated by changes in postprandial fatty acid concentrations or by hormonal signals from adipocytes, but a possible association of low-GI diets with some other dietary factor such as chromium must not be excluded. Proof of the clinical value of low-GI diets awaits prospective trials, which should include short-term observations covering periods of metabolic stress induced by surgery as well as long-term trials with clinical endpoints.     

Alcohol and coronary heart disease

The data on two questions are reviewed: does heavy alcohol intake increase the risk of coronary heart disease (CHD)? And, is moderate intake protective? Identified alcoholics and problem drinkers have an increased risk of CHD, and in Britain there is a correlation among 22 towns, between the proportion of heavy drinkers in a town and CHD mortality. Of seven longitudinal studies reviewed, one shows heavy drinkers to have an increased CHD incidence. An inverse association between alcohol consumption and CHD mortality is seen in international comparisons and in time trends in the USA. Of six case-control studies reviewed from England and the USA, all show an inverse association between CHD and alcohol consumption which persists after control for other risk factors. Longitudinal studies, in Japanese-Americans, white American men and women, British civil servants, Puerto Ricans, Yugoslavs and Australians, all show moderate drinkers to have a lower CHD risk than abstainers. Abstainers are likely to differ from moderate drinkers in a number of ways. To date it has not proved possible to show that any of these differences account for the higher CHD risk of abstainers. The apparent protective effect is not large (RR = 0.5) but the consistency of the association and the existence of plausible mechanisms increase the likelihood that the negative association is causal. However, if alcohol intake were to increase in the population the social and medical consequences would be large. An increased intake is therefore not recommended as a community measure for CHD prevention.