神经性厌食症患者生命质量的初步研究

Objective The health-related quality of life of patients with anorexia nervosa (AN) was com-pared to published norms for the general Chinese people. Methods 49 AN outpatients or inpatients were evalua-ted by the Self-rated medical outcomes study SF-item Short-Form Health Survey(SF-36). Results The factor scores of role-physical, general health,social function,role emotion, mental health in SF-36 were found significantly lower in AN patient (44.4±36.2,53.3±16.3,56.6±24.1,45.6±38.9,47.5±21.4, respective ) compared with control group(P<0.01 ). The factor scores of physical function,bodily pain, general health in SF-36 were found significantly lower in AN patient with long period (85.5±13.4,74.0±20.3,45.8±14.7, respective) compared with AN patient with short period (93.2±6.6,87.2±14.7,57.5±15.7, respective) (P<0.05). Con-clusions AN is associated with impaired health-related quality of life.     

维持性血液透析述情障碍患者医学应对方式和生活质量的研究

Objective To discuss alexithymia in patients with maintenance hemodialysis and its impact on medical coping style and the ability of daily living. Methods The patients with end-stage renal disease treated by the maintenance hemodialysis (MHD) were divided into 2 groups, namely, alexithymia group (total score>60) and non-alexithymia group (total score <50) ,according to the Toronto Alexithymia Scale (TAS-20). The Medical response to the questionnaire (MCMQ) and the activities of daily living scale (ADL) were used to evaluate the patients. Results The TAS-20 score was (72.31±12.28) in 67 cases of patients with MHD. Among these, 31 cases for TAS-20 total score>60 points ,with an average score (82.37±15.84) and 26 cases for TAS-20 total score <50 points, with an average score (50.17±10.24). There was significant difference (t=8.90, P<0.01). The face factor score of MCMQ was significantly lower in alexithymia groups than that in non-alexithymia group,while the avoidance and subordination factor score was significantly higher than that in non-alexithymia group(P<0.01 or 0.05). The ADL scores and factor scores of the alexithymia group were significantly higher than that of non-alexithymia group,and there was a significant difference (t=3.53, P<0.01). Correlation analysis showed that TAS-20 score and the face factor score of MCMQ was significantly negatively correlated with MCMQ e-vasive and subordination factor,and factor scores and ADL score was significantly positively correlated (P<0.01 or 0.05). Conclusion MHD patients in the alexithymia group tend to use and yield response to avoid negative cop-ing style and less use of active coping style. The quality of life and activities of daily living of MHD patients in alex-ithymia group are worse than that of the non-alexithymia group.     

丙戊酸镁缓释片与丙戊酸钠缓释片治疗躁狂发作的对照研究

Objective To compare the efficacy and side effects f magnesium valprote extended action tab-let and sodium valproate sustained-release tablets in treatment of patients with mania. Methods A total of 60 pa-tients with mania randomly divided into two groups,study group with magnesium valprote extended action tablet and control group with sodium valpreate sustained-release tablets for treatment of three weeks. They were assessed and analysed contrastively using with Bech-Rafaeisen Mania Scale(BRMS) and Treatment Emergent Side Effect Scale (TESS) before treatment and in the Ist,2nd and 3rd weekend after treatment. Results There were no signifi-cantly differences between study group and control group for scores of BRMS in the I st (as follows :21±3.6,20 ± 4.3) ,2nd (as follows:11±2.3,12±3.5)and 3rd (as follows:6±1.7,5±2.4) weekend after treatment(t=3.27 ～5.34, P=0.053～0.082). In the 1st weekend of treatment,the total scores of TESS (3.12±2.37) in study group were significantly lower than those (4.57±2.83) in control group(t=3.58, P=0.002). There were no significantly differences between study group and control group for scores of TESS in the 2nd (as follows:2.95±2.26,3.15±2.01) and 3rd ( as follows: 1.43±2.04,1.72±2.31 ) weekend after treatment(t = 2.48～3.06, P = 0.552～0.931 ). Conclusion Magnesium valprote extended action tablet is effective in treating mania without severe side effects.     

情绪启动对大学生内隐和外显记忆影响的心境一致性记忆效应

Objective To investigate the different effect of positive and negative emotion induced by film clips on explicit and implicit memory,and whether there is mood congruency effect. Methods Thirty participants who were randomly assigned to three experimental groups were investigated. They were exposed in different film clips and then worked on memory task. After each emotional condition,the 5-point Self Assessment Scale was registered , Buchner's processing dissociation corrected model was employed to separate explicit and implicit memory. Results (1) The emotion arousal level of different films is significantly different, the scores of negative film and positive film were more than that of neutral film( (3.24 ± 1.02),(2.85 ± 1.35),(1.12 ± 1.42) , P＜0.01) ; the scores of emotional valence of positive,negative and neutral priming condition were (4. 10 ±0. 20), (3. 60 ± 0.22) and (3.20 ±0. 97), and there was a significant difference between emotion priming conditions (F(2,27) = 46.81, P＜ 0. 01). (2) There was a significant difference among different emotion priming conditions in R (F(2,87) = 30.129, P＜0.05) .and there was no significant difference among different emotion priming conditions in A. (3) In R,there was a main effect in emotional words(F(2,81) = 10.516, P＜0.05) ,the R scores of neutral words were significantly higher than those of negative words(P＜0.01) ,there was a main effect in emotion priming conditions(F (2,81) =10.516, P＜0.05) ,the R scores of positive emotion priming group and neutral emotion priming group were significantly higher than those of negative emotion priming group (P＜0.05). There was an interaction of emotional words and emotion priming conditions(F(4,81) = 10.640, P ＜ 0.01). Under positive emotion priming condition, the R scores of positive and neutral words were significantly higher than those of negative words (P＜0.05);under negative emotion priming condition, the R scores of negative words were significantly higher than those of positive words (P ＜0.05); under neutral emotion priming condition, the R scores of positive and neutral words were significantly higher than those of negative words (P＜0.05). (4) In A, the main effect of emotion priming conditions and emotional words and interaction effect between them were not significant(P＞0.05). Conclusions Explicit memory showed mood congruency memory effect,but implicit memory,neither the positive emotion priming group nor the negative emotion priming group exhibited mood congruency memory effect.     

夫妻心理健康、婚姻质量及其关系研究

Objective To understand the relationship between spouses' marital quality and their mental health.Method 384 pairs of couples from 28 provinces in China were examined with the Marriage Perception Scale(MPS) and Symptom Checklist 90 (SCL-90).Result ( 1 ) Husbands' scores of couple conflict( 10.85 ±5.02) were significantly lower than wives' scores of couple conflict ( 11.66 ± 5.63 ) (P ＜ 0.05 ).( 2 ) Husbands' seores in the 5 factors of SCL-90 ( symptoms that somatization ( 1.44 ± 0.50 ), interpersonal sensitivity ( 1.57 ±0.54),depression( 1 .50 ± 0.52 ) ,anxiety ( 1.46 ± 0.54 ), panic ( 1.38 ± 0.55 ) ) were significantly higher than wives' in the 5 factors of SCL-90[symptoms that somatization ( 1.52 ± 0.54 ), interpersonal sensitivity ( 1.66 ±0.58), depression (1.59 ±0.59 ), anxiety ( 1.55 ± 0.58 ), panic ( 1.47 ± 0.59 )] (P ＜ 0.05 ).( 3 ) Individual's MPS and its SCL-90,spouses' MPS andits SCL-90 correlated as well( r=-0.372 ～0.239)(P＜0.01 ).Conclusion Couples are similar in their marriage perceptions.Husbands are psychological healthier than their spouses'.Individual marriage perception is correlated with his/her mental health level and his/her spouses' as well.     

夫妻心理健康、婚姻质量及其关系研究

Objective To understand the relationship between spouses' marital quality and their mental health.Method 384 pairs of couples from 28 provinces in China were examined with the Marriage Perception Scale(MPS) and Symptom Checklist 90 (SCL-90).Result ( 1 ) Husbands' scores of couple conflict( 10.85 ±5.02) were significantly lower than wives' scores of couple conflict ( 11.66 ± 5.63 ) (P ＜ 0.05 ).( 2 ) Husbands' seores in the 5 factors of SCL-90 ( symptoms that somatization ( 1.44 ± 0.50 ), interpersonal sensitivity ( 1.57 ±0.54),depression( 1 .50 ± 0.52 ) ,anxiety ( 1.46 ± 0.54 ), panic ( 1.38 ± 0.55 ) ) were significantly higher than wives' in the 5 factors of SCL-90[symptoms that somatization ( 1.52 ± 0.54 ), interpersonal sensitivity ( 1.66 ±0.58), depression (1.59 ±0.59 ), anxiety ( 1.55 ± 0.58 ), panic ( 1.47 ± 0.59 )] (P ＜ 0.05 ).( 3 ) Individual's MPS and its SCL-90,spouses' MPS andits SCL-90 correlated as well( r=-0.372 ～0.239)(P＜0.01 ).Conclusion Couples are similar in their marriage perceptions.Husbands are psychological healthier than their spouses'.Individual marriage perception is correlated with his/her mental health level and his/her spouses' as well.     

缓解期抑郁症伴人格障碍患者功能失调性认知特点研究

Objective To compare the differences of dysfunctional attitudes between depressive patients in remission with and without personality disorder (PD).Methods A total of 72 patients with remitted depression were assessed with Personality Diagnostic Questionnaire-4 (PDQ-4) and Dysfunctional Attitudes Scale (DAS).They were divided into PD group ( n = 20 ) and non-PD group ( n = 31 ) according to their PDQ-4 scores.The differences of dysfunctional attitudes between the two groups were compared.Results The total score and seven factors' scores of DAS of the PD group were ( ( 142.40 ± 20.68 ), ( 16.55 ± 3.76), ( 16.35 ± 5.45 ),( 18.35 ± 4.15 ), ( 17.90 ± 3.55 ), ( 18.85 ± 5.72 ), ( 18.25 ± 4.82 ), ( 20.75 ± 5.54) respectively) significantly higher than the counterparts of the non-PD group, which were( ( 113.61 ± 19.08 ), (13.71 ± 2.88 ), ( 12.45 ±2.87) ,(12.55 ±3.60),(13.90 ±3.72) ,(14.68 ±3.51),(14.16 ±4.12),(15.81 ±4.78)) respectively (P＜ 0.01 ).Conclusion Remitted depressive patients with personality disorders have more cognitive distortions than those without personality disorders.     

缓解期抑郁症伴人格障碍患者功能失调性认知特点研究

Objective To compare the differences of dysfunctional attitudes between depressive patients in remission with and without personality disorder (PD).Methods A total of 72 patients with remitted depression were assessed with Personality Diagnostic Questionnaire-4 (PDQ-4) and Dysfunctional Attitudes Scale (DAS).They were divided into PD group ( n = 20 ) and non-PD group ( n = 31 ) according to their PDQ-4 scores.The differences of dysfunctional attitudes between the two groups were compared.Results The total score and seven factors' scores of DAS of the PD group were ( ( 142.40 ± 20.68 ), ( 16.55 ± 3.76), ( 16.35 ± 5.45 ),( 18.35 ± 4.15 ), ( 17.90 ± 3.55 ), ( 18.85 ± 5.72 ), ( 18.25 ± 4.82 ), ( 20.75 ± 5.54) respectively) significantly higher than the counterparts of the non-PD group, which were( ( 113.61 ± 19.08 ), (13.71 ± 2.88 ), ( 12.45 ±2.87) ,(12.55 ±3.60),(13.90 ±3.72) ,(14.68 ±3.51),(14.16 ±4.12),(15.81 ±4.78)) respectively (P＜ 0.01 ).Conclusion Remitted depressive patients with personality disorders have more cognitive distortions than those without personality disorders.     

Relationship of the plasma urotensin Ⅱ with proadrenomedullin N-terminal 20 peptide in patients with congestive heart failure

Objective: To understand the role of urotensin Ⅱ ( U Ⅱ ) and proadrenomedullin N-terminal 20 peptide ( PAMP) , a fragment of proadrenomedullin ( proADM ) possessing biological activity, in the pathophysiological process of congestive heart failure (CHF) by observing the variation of their plasma levels and exploring their interrelations. Methods: Plasma U Ⅱ and PAMP levels were measured by radioimmunoassay in 52 patients with CHF and 14 healthy subjects. Left ventricular ejection fraction (LVEF) and the ratio of E/A were determined by echocardiography. Results: The plasma U Ⅱ level was significantly lower in patients with CHF than the healthy subjects (1.5±1.0 pg/ml vs 4. 3±1.2 pg/ml, P < 0.05), while plasma PAMP level was significantly higher in the former group (30. 6±5. 8 pg/ml vs 21.0±6.6 pg/ml P < 0. 05 ). The levels of U Ⅱ and PAMP were parallel with the severity of CHF, and significant correlation of plasma levels of U Ⅱ with LVEF (r=0.530, P=0.000) and the ratio of E/A (r=0.618, P = 0.     

麻疹的双相移位研究进展

近年新生儿、婴儿、成人麻疹患者逐年增加,临床表现一般仍较典型,成年人麻疹患者全身中毒症状较重。麻疹抗体检测结果阳性是主要的诊断依据。麻疹发病的双相移位的机理可能是,免疫保护力不足,婴儿出生时麻疹抗体力低。孕期母传胎的麻疹抗体减弱,母经乳汁传给婴儿的抗体减弱,成人麻疹抗体水平逐年下降。预防措施是怀孕前给予育龄妇女麻疹疫苗接种,鼓励母乳喂养,麻疹疫苗计划免疫适当提前,在成人追加麻疹疫苗的免疫,加强病毒变异的研究等。     

正常增殖期子宫内膜细胞增生状态的定量观察

以＾３氢－胸腺嘧啶核苷放射自显影法及ＨＥ染色，观察并分别测定了１８例正常子宫内膜增殖中期，１５例增殖晚期的腺上皮细胞或间质细胞的标记指数、分裂指数。结果显示：子宫内膜增殖晚期腺上皮细胞或间质细胞之ＬＩ均明显高于增殖中期。同时，增殖晚间质细胞之ＭＩ也明显高于增殖中期，即此两种细胞在增殖晚期中增生明显，其增生状态初步获得了定位定量测定的正常值。     

尿微量白蛋白检测在继发性肾脏疾病中的临床意义

目的探讨尿微量白蛋白（m-Alb）检测在继发性肾脏疾病中的临床意义。方法采用Beckman Immage全自动特种蛋白分析仪对糖尿病组、高血压组、心脏病组患者进行了m-Alb测定,同时与健康组结果作对比。结果m-Alb检测糖尿病组为3.7±5.26mg/dl,高血压组为7.5±8.18mg/dl,心脏病组为7.8±3.76mg/dl,健康组为0.66±0.48mg/dl,各试验组m-Alb增高百分率为糖尿病组48.9%,高血压组37.5%,心脏病组26.9%。结论尿蛋白阴性的糖尿病、高血压、心脏病患者进行m-Alb检测,可以监测病程的进展。     

人工全髋关节置换术的手术配合

目的：介绍人工全髋关节置换术的手术配合做法;方法：主要在手术配合的六个方面,解决防感染、防栓塞等问题。结果：30例人工全髋关节置换术均获成功,结论：手术配合是护士责任心和基本功的全面体现,对提高手术效果有至关重要的影响。     

80例局限性银屑病误诊原因分析

本文报告80例局限于小腿或手或足的银屑病。均经皮肤组织病理检查确诊。因部位比较特殊。受多种理化因素影响,使皮疹形态发生轻重程度不同的变化,常看不到典型损害,因而误诊为神经性皮炎,湿疹,慢性皮炎及癣等。作者对误诊原因进行了分析后,提出了鉴别诊断方法。     

腰椎间盘突出症再次手术的原因分析

目的解决腰椎间盘突出症手术中神经压迫。方法对1980～1998年再手术资料进行统计分析,讨论分析再手术原因,再次手术前影像学检查,观察病理变化以确定再手术方法。结果对11例随访6个月～1年,优7例(68．4％),良3例(36．8％),差1例(2．8％)。结论初次手术前详细查体和分析X线片,术中用导尿管和神经剥离探查,尽量避免髓核遗留,手术范围不宜太大,尽量减少对软组织和脊柱结构的破坏,避免形成硬膜囊与神经根粘连而致单纯形疤痕。     

妊娠晚期重度妊高征的监测

重度妊高征表现为高血压、蛋白尿、浮肿等症状 ,严重可以导致母婴死亡。对妊娠足月的重度妊高征 ,可以根据其临产与否及宫颈条件 ,立即决定其为阴道分娩或是剖宫产术。对于妊娠晚期的重度妊高征 ,因其胎龄不足月 ,胎儿生长发育及胎肺成熟度情况需通过一定时间的治疗 ,根据其病情变化来决定其治疗方案或终止妊娠的时机[1,2 ] 。这就需要我们对这一阶段的治疗进行监测 ,防止母儿并发症的发生。现将 2 0 0 0年至今我院收治妊娠晚期重度妊高征 30例的监测结果回顾分析如下。1　资料和方法1.1　研究对象　选择孕 31～ 36周重度妊高征 30例 ,其中 …