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1.
目的探讨。肾动脉多支畸形的供。肾在体外血管重建中的方式及其在肾移植中的应用。方法对5例肾动脉多支畸形供肾的修整采取截取受者同侧髂内动脉的方法,依据供肾动脉的分支数而保留髂内动脉的分支数;在体外将供肾动脉各分支与髂内动脉大分支的开口进行端端吻合,然后将髂内动脉主干与受者髂外动脉行端侧吻合。将肾动脉重建后的供肾应用于双侧肾动脉瘤患者的自体肾移植术1例、亲属活体供肾肾移植术3例和尸体肾移植术1例。结果术后5例受者均未发生外科并发症。1例术后发生短暂的急性。肾小管坏死,但48h后进人多尿期,肾功能恢复顺利。术后随访10-36个月,受者移植。肾功能全部正常,肾动脉及分支未发生血栓或闭塞。结论采用受者的髂内动脉体外重建供。肾动脉的方法,可有效修复肾动脉3支以上以及。肾动脉过短的供肾,是一种安全可行的血管重建的方法,血管并发症较低,可有效应用于肾移植。  相似文献   

2.
在肾移植中,常会遇到供受者动脉病变及多支血管变异,如处理不当,常导致移植肾失败或肾功能不全.本院共施行肾移植350例,其中受者髂内动脉严重粥样斑块硬化、管腔接近闭塞者30例,供肾多支动脉变异36例,供肾动脉与髂内动脉管径悬殊较大8例,均作了合理的处理.术后移植肾血供良好,1年后随访,吻合血管通畅,肾功能正常,现将其处理经验介绍如下.1 处理方法1.1 髂内动脉严重粥样斑块硬化的处理髂内动脉管腔很小,接近闭塞.这种髂内动脉如与肾动脉吻合,开放血流后移植肾常供血不足,肾色虽鲜艳,但充盈张力差,术后常发生急性肾衰及无尿,导致肾移植失败.对此,我们有沉痛的失败教训.后来我们对25例粥样斑块硬化患者采取髂内动脉斑块切除,然后与肾动脉作端端吻合,开放血流后移植肾充盈张力良好.对5例斑块不能切除者,采取肾动脉与髂外动脉端侧吻合,同样取得良好效果.术后随访1年,肾功能正常,肾动脉无血管杂音,B超、彩色多普勒血流图、肾动脉造影(部分患者)未发现异常变化.  相似文献   

3.
肾移植后血管并发症的诊治体会   总被引:3,自引:0,他引:3  
目的探讨。肾移植术后血管并发症的特点和诊治方法。方法回顾34例术后并发血管疾病的。肾移植患者临床资料,对其发病特点和诊治方法进行分析总结。结果34例患者中,并发移植肾动脉梗阻13例,移植肾动脉出血8例,动脉吻合口破裂7例,移植肾静脉梗阻4例,髂外动脉瘤和髂外静脉栓塞各1例。21例经彩色多普勒血流显像(CDFI)作出诊断,其中10例进一步行磁共振血管成像(MRA)明确诊断。5例移植。肾动脉狭窄患者中,3例放置血管内支架扩张后肾功能恢复良好,分别随访8、10、14个月,血肌酐维持在115~135μmol/L;1例将与髂内动脉端端吻合的移植。肾动脉改为与髂外动脉端侧吻合,术后至今1个月,血肌酐降至正常水平;1例MRA显示不完全狭窄,给予保守治疗,至今观察21d,血肌酐持续降低。3例静脉梗阻患者经手术解除梗阻,其中1例死于心力衰竭,另2例随访13、36个月,肾功能恢复良好。1例髂外静脉栓塞患者术后死于移植肾破裂。其余患者均切除移植肾。结论。肾移植术后的血管并发症进展迅速,应根据具体情况及时采取相应治疗手段,处理不及时往往导致移植肾功能丧失,因此早期诊断非常重要,CDFI可作为首选筛查手段。  相似文献   

4.
目的 探讨亲属活体供肾动脉变异的血管重建方法.方法 在104例亲属活体供肾移植中,有14例供肾动脉变异.供肾动脉变异的分类和血管重建方法分别为:(1)单支动脉较早分支型2例,取肾时分支受损,分别用受者髂内动脉及其分支、腹壁下动脉离体重建受损动脉.(2)双支动脉型10例,4例用受者髂内动脉及其分支离体重建血管,3例用受者腹壁下动脉与较细分支于体内吻合,1例较短肾动脉与较长肾动脉端侧吻合,1例较细副.肾动脉与主肾动脉端侧吻合,1例双支分别与髂外动脉端侧吻合.(3)3支动脉型2例,1例用受者髂内动脉及分支离体重建血管,1例结扎细小分支后,将较细的副肾动脉与主肾动脉端侧吻合.14例血管重建后,分别将供肾动脉较粗支和/或髂内动脉主干端与受者髂外动脉端侧吻合.结果 术后各支动脉血流通畅,移植.肾血液供应丰富、均匀.12例肾功能早期恢复正常,其中1例术后第14天发生急性排斥反应.1例术后即发生急性排斥反应;1例血肌酐下降缓慢.随访至2008年7月,除1例动脉粥样硬化较重的受者(三支动脉)下极动脉栓塞,血肌酐升高并稳定在170μmol/L外,其余患者动脉血流通畅,血液供应丰富、均匀.结论 供肾动脉变异时,利用所得供肾动脉的自身条件重建血管,或用受者髂内动脉及分支或腹壁下动脉重建血管,可获得较好的移植肾功能.受者动脉粥样硬化较重,同时有较细肾动脉支做重建吻合时,应注意该支动脉发生栓塞的可能.  相似文献   

5.
糖尿病性肾病合并髂动脉严重硬化患者的肾移植手术处理   总被引:2,自引:0,他引:2  
目的 探讨糖尿病肾病合并髂动脉严重硬化患的肾移植手术技巧。方法 15例糖尿病肾病合并髂动脉严重硬化的肾移植患,8例次清除髂内动脉内膜硬化斑块后,由钛轮钉端端吻合动脉;10例次剥离髂总或髂外动脉硬化内膜,与肾动脉端侧吻合。结果 术后心跳骤停死亡1例;1例病人连续3次发生移植肾血流灌注不足导致的移植肾原发性无功能,第4次肾移植肾功能良好;其余13例病人首次移植术后肾功能良好。结论 严重动脉硬化患的动脉吻合困难,为保证移植肾有足够的血流灌注,应根据病人的不同情况选择吻合血管,并行硬化内膜切除术。  相似文献   

6.
糖尿病髂动脉硬化患者肾移植术51例报告   总被引:3,自引:0,他引:3  
目的探讨糖尿病髂动脉硬化患者的肾移植手术特点。方法51例糖尿病合并髂动脉硬化的肾移植受者共行肾移植术54例次。其中肾动脉与髂外动脉直接端侧吻合13例次;切除硬化内膜,肾动脉与髂总/髂外动脉端侧吻合19例次;切除硬化内膜,肾动脉与髂内动脉钛环钉法端端吻合22例次。结果发生移植肾血流灌注不足致移植肾原发性无功能3例次,发生移植肾功能延迟恢复9例次(17.6%),其余42例次移植肾功能恢复良好。围手术期死亡2例(均为心跳骤停)。随访11—70个月,1年人/肾存活率为89.8%/87.8%,3年存活率为84.4%/81.3%。结论糖尿病髂动脉硬化患者移植肾动脉吻合困难,为保证移植肾有充足的血流灌注,应根据患者的不同情况选择吻合血管,并行硬化动脉内膜切除术。合并冠心病的患者肾移植术前应先行心肌再血管化手术。  相似文献   

7.
肾移植血管吻合技巧   总被引:1,自引:0,他引:1  
血管吻合技术的好坏直接关系到肾移植手术的成败。提高血管吻合手术技巧的目的,也在于避免肾移植术后常见血管并发症如移植肾血管梗阻、栓塞,移植肾动脉破裂出血,吻合口破裂出血,移植肾动脉瘤,移植肾动脉狭窄等[1]。一、肾移植静脉吻合技巧供肾静脉常与受体髂外静脉端侧吻合,髂外静脉有血栓形成或儿童肾移植患者供肾静脉常与下腔静脉端侧吻合。在静脉吻合之前,须摆好供肾与吻合血管之间的关系,切勿让供肾静脉扭曲。为防止静脉吻合口狭窄,受者静脉切口要足够大,与供肾静脉口径相匹配为原则。左肾静脉一般长度足够,不需延长。右肾静脉相对较短…  相似文献   

8.
目的 改进门静脉回流式肠道引流的胰肾同侧联合移植术的动脉重建方法.方法 供者采用肝胰肾脾联合切取法,并切取供者髂血管备用.修整供者器官时,将肝总动脉与胃十二指肠动脉端端吻合,以重建胰十二指肠动脉弓;将髂总静脉与门静脉端端吻合,以延长门静脉1~2 cm;将髂外动脉与肠系膜上动脉和腹腔干共同的腹主动脉袖片行端端吻合,备用.胰腺移植时,将供者延长后的门静脉与受者肠系膜上静脉行端侧吻合,将供者髂总动脉及髂内动脉经末端同肠系膜打孔穿出后,供者髂总动脉与受者髂外动脉行端侧吻合,供者髂内动脉用血管夹暂时夹闭,准备与供肾动脉吻合.供者十二指肠与受者空肠用吻合器行侧侧吻合.肾移植时,将供肾静脉与受者髂外静脉行端侧吻合,肾动脉与夹闭备用的供者髂内动脉行端端吻合,开放肾血流后,将移植肾经切口置于右下腹部侧腹膜外同定,并在腹膜外吻合输尿管与膀胱.结果 除1例术后第50天时因腹腔感染导致多器官功能衰竭而死亡外,其他3例术后均恢复顺利.术后对3例存活患者随访了24~27个月,患者移植物功能良好,完全停用胰岛素,血清肌酐为72.5~119.7μmol/L.结论 门静脉回流式肠道引流的胰肾同侧联合移植术较传统术式操作简单,而十二指肠动脉弓的重建改善了胰腺及十二指肠的血液供应.术中利用供者髂总动脉搭桥,将供肾动脉吻合到供者髂内动脉的术式可以减少在受者严重钙化的周围血管上的操作次数,同时为患者保留了左侧髂动脉.  相似文献   

9.
目的 探讨手助腹腔镜法活体取肾、离体肾动脉瘤切除、肾动脉重建和自体肾移植技术治疗复杂性肾动脉瘤的安全性和可行性.方法 2006年10月收治1例42岁复杂性肾动脉瘤男性患者.术前彩超、CT及DSA检查显示左肾动脉瘤3.4 cm×4.3 cm×4.5cm大小,瘤内有部分血栓形成,位于左肾动脉主干分叉部,累及5支分支动脉,邻近肾门.患者有高血压病史,药物控制不佳.术中采用手助腹腔镜法活体取肾成功后,立即对离体肾脏采用4℃肾脏保存液灌注,低温保护肾脏.体外进行肾动脉瘤切除:切取自体右髂内动脉体外行肾动脉重建,最后将肾脏异位移植至右侧髂窝.结果 患者手术成功,围手术期未出现并发症.术后.肾功能正常:彩超复查显示右侧髂窝移植肾动脉及其分支血流通畅无狭窄,肾静脉血流通畅,输尿管无狭窄.术后13个月随访,血压恢复正常,肾功能正常.结论 离体肾动脉瘤切除和自体.肾移植术治疗复杂性肾动脉瘤微创、安全、可行.  相似文献   

10.
活体肾移植血管重建69例临床分析   总被引:1,自引:0,他引:1  
目的 介绍活体肾移植血管重建的临床经验.方法 自2005年12月至2008年11月共行活体肾移植69例,供者手术均采用十一肋间小切口开放手术.58例单支肾动脉除2例外均采用肾动脉与髂外动脉端侧吻合重建血管,用4 mm打孔器作髂外动脉开口;6例副肾动脉分别采用原位(肾下极副肾动脉)或离体腹壁下动脉(肾上极副肾动脉)重建血管;3例双支肾动脉根据两支动脉口径不同采用不同方法重建血管;2例3支肾动脉采用受者离体髂内动脉重建血管.结扎多支肾静脉中较小的肾静脉只吻合其较大的主干,当两支肾静脉口径相近时,则将其整形为一个开口后吻合.结果 所有血管吻合均一次完成,开放血流时吻合口均通畅;所有供者和受者术后均恢复顺利,受者未发生血管重建相关并发症;随访1个月~3年,供受者均存活, 受者除1例血肌酐250~300 μmol/L外,68例血肌酐维持在70~150 μmol/L.结论 该活体肾移植血管重建方式安全、实用、操作方便,多支供肾动脉及多支供肾静脉均能较好重建,移植肾功能良好.  相似文献   

11.
A 49-year-old man underwent living donor renal transplantation in November 2005. The transplant renal artery was anastomosed to the right internal iliac artery with an end-to-end anastomosis. The patient achieved immediate graft function and the allograft was normally perfused. Seven weeks later, renal allograft function deteriorated with a serum creatinine level increased to 244 micromol/L. An ultrasound scan revealed adequate perfusion to the kidney and the absence of hydronephrosis. A transplant biopsy revealed Banff IB rejection, which was treated with high-dose prednisolone. Following biopsy, the patient's renal function rapidly deteriorated with a serum creatinine level increased to 627 micromol/L, requiring hemodialysis. A computed tomography (CT) angiogram demonstrated a 6-cm diameter pseudoaneurysm arising from the internal iliac artery with absence of kidney perfusion. The aneurysm was accessed percutaneously with a 4-F catheter and 1000 U of human thrombin injected, resulting in partial thrombosis of the pseudoaneurysm. A balloon expandable covered metal stent was then placed across the site of the transplant renal artery anastomosis, resulting in successful occlusion of the aneurysm. Intrarenal blood flow was established by dilating 2 intrarenal branches with 3-mm diameter balloons. The serum creatinine level started to decrease within 24 hours of the procedure and renal function improved rapidly to a level achieved immediately after transplantation. Three months later the patient had a well-functioning allograft with a serum creatinine level of 176 micromol/L, follow-up CT scan demonstrated good perfusion of the transplanted kidney with no further change in the pseudoaneurysm. At 12 months follow-up the patient remains with a well-functioning allograft.  相似文献   

12.
We report a case of living related renal transplantation that used the recipient's saphenous vein as a graft to extend the length of the right donor renal vein.A 41-year-old woman underwent ABO-incompatible living related renal transplantation from her 74-year-old mother in November 2014.A retroperitoneal laparoscopic right donor nephrectomy was performed, because the right kidney showed a cyst on preoperative computed tomography.As the right kidney after donor nephrectomy had a short renal vein and the kidney was large at 280 g, anastomosis with the external iliac vein was difficult. Therefore, we obtained the recipient's 15-cm-long right saphenous vein and created a 1 cm saphenous vein graft. We anastomosed 1 side of the saphenous vein graft to the allograft renal vein in bench surgery and performed end-to-side anastomosis of the other end to the recipient's external iliac vein. The allograft renal artery was used to perform end-to-end anastomosis to the recipient's internal iliac artery. Allograft kidney function was good after transplantation.When the longer axis of the renal graft vein is short, as in the right kidney, a saphenous vein graft may be useful.  相似文献   

13.
Common iliac artery stenosis after renal transplantation is a rare complication; it can occur in the course of hypertension and renal dysfunction. We report a case of suspected renal allograft rejection with iliac artery stenosis proximal to a transplanted kidney. A 52-year-old man with a history of cadaveric kidney transplantation 26 years previously underwent a second cadaveric kidney transplantation in the left iliac fossa because of graft failure 3 years before. In June 2012, the patient had progressive renal dysfunction. In July, a percutaneous needle biopsy was taken, and it showed no rejection; however, his renal function continued to get worse through September. A percutaneous allograft renal biopsy was performed under ultrasound guidance and showed hyperplasia of the juxtaglomerular apparatus and renin granules. Magnetic resonance angiography was used to evaluate the arteries in the pelvis and showed left common iliac artery stenosis, and a stent was placed. After percutaneous intervention, the patient's ankle brachial pressure index was within the normal range and the allograft function had improved.  相似文献   

14.
A 44 year old man with end-stage renal failure from nephro-angiosclerosis and with an abdominal aortic aneurysm involving also the common iliac arteries simultaneously underwent an abdominal aneurysmectomy using a standard Dacron graft and a living related renal transplantation. An original technic was used in order to prevent an anastomotic stenosis of the artery: the donor's renal artery was sutured end- to side on the Dacron prosthesis via a venous patch from the donor's renal vein. The post-operative course was uncomplicated; one year after the operation, the renal function is excellent (creatine: 1.6 mg/dl) and the blood pressure is normal.  相似文献   

15.
BACKGROUND: Ninety-four patients (37 male, 57 female; mean age, 51.0 years) underwent reconstruction for renal artery aneurysm (RAA) between 1980 and 2001. RAAs were present in 52 patients in the right kidney, in 29 patients in the left kidney, and in 13 patients in both kidneys. Eighty-three aneurysms were located in the mainstem, 49 in a branch artery, and four in an accessory artery. Additional ipsilateral renal artery stenoses (RAS) occurred in 26 patients, bilateral RAS in 18, and contralateral RAS in six. The causes of RAA were fibromuscular dysplasia (n = 48), atherosclerosis (n = 28), dissection (n = 7), aortic coarctation (n = 5), arteritis (n = 3), giant cell arteritis (n = 1), Marfan's syndrome (n = 1), and trauma (n = 1). Seventy-five patients had hypertension, 14 were asymptomatic, and five had rupture. Indications for RAA repair concerned aneurysms with 1 cm or more diameter in combination with risk factors of hypertension, ipsilateral and contralateral stenosis, and childbearing age in women. Without risk factors, aneurysm size eligible for reconstruction was limited to 2 cm or more. METHODS: Methods applied for reconstruction in 107 kidneys and 136 aneurysms included aneurysm resection with tailoring (n = 37), saphenous vein graft interposition (n = 40), tailoring and saphenous vein graft interposition (n = 7), resection and reanastomosis (n = 14), saphenous vein graft interposition and resection and reanastomosis (n = 3), polytetrafluoroethylene bypass (n = 5), and homologous vein graft interposition (n = 1). Four reconstructions had to be performed ex situ because of multiple branch involvement in three patients and rupture in one. In all patients, the concerned kidney was protected with hypothermic flush perfusion with addition of heparin and prostaglandin E1. RESULTS: The overall morbidity rate was 17%, including one early graft occlusion, one partial thrombosis of the renal artery that necessitated fibrinolytic therapy, and a branch artery stenosis after tailoring managed with aortorenal bypass. The mortality in elective cases was null; one patient died of myocardial infarction 2 days after an emergency operation for ruptured RAA. The technical primary success rate was 96.8%; the secondary success rate was 98.9%. After a follow-up period from 1 to 143 months (mean, 46 months) in 83 patients (88%), 67 (81%) had patent renal arteries free of stenoses. Among six patients with RAS, four underwent successful reoperation, five had mainstem occlusions, three had segmental artery occlusions, and two underwent nephrectomy. Concerning the patients who underwent reoperation, percutaneous transluminal angioplasty was considered seriously but assessed as inappropriate because of long extension of stenosis or involvement of branch arteries. Hypertension was cured in 19 patients (25%) and improved in 17 (22%). CONCLUSION: Surgical reconstruction of RAA is a safe procedure that provides good long-term results, prevents aneurysm rupture, cures or improves hypertension in about half of the cases, and can be achieved with autogenous reconstruction in 96%.  相似文献   

16.
Two cases of renal allograft artery stenosis secondary to circumferential malalignment of the anastomotic site with the recipient external iliac artery are presented. One stenosis was temporary with apparent resolvement by dilatation of the allograft artery; the other was permanent and required operative correction by patch angioplasty. Circumferential malalignment of the arterial anastomotic site, when the renal artery is placed end to side into the recipient external iliac artery, is proposed as an etiologic mechanism for both temporary and permanent renal allograft artery stenosis. Careful attention to the final position of the graft in the retroperitoneum when the site for arterial anastomosis is chosen will prevent this complication of human renal allotransplantation.  相似文献   

17.
An anastomotic aneurysm following aortic or iliac surgery poses specific problems. Conventional open repair is difficult and can lead to life-threatening complications. Aneurysm exclusion is necessary to prevent rupture or peripheral embolism. We report on three patients who had undergone conventional surgical correction of an infrarenal aneurysm years ago: one patient received a tube graft and two patients a bifurcation prosthesis. One patient developed a proximal anastomotic aneurysm, one a distal anastomotic aneurysm (following tube graft), and one an aneurysm near the iliac junction. These anastomotic aneurysms were treated endovascularly: one bifurcation stent graft was implanted, one aortic monoiliac stent graft and crossover bypass, and one iliac stent graft with previous coiling of the internal iliac artery. Exclusion of the aneurysm was successful in all three cases. Endovascular treatment offers the advantage of less surgical trauma compared to open repair.  相似文献   

18.
Kidneys with multiple renal arteries are increasingly procured for transplantation. To compare the outcomes of kidney transplantation using allografts with multiple arteries, we studied long-term graft function and survival according to their number of arterial anastomoses during an 18-year period from July 1, 1990, through December 31, 2008, in which only the recipient's external iliac artery or internal iliac artery was used for anastomosis (n = 1186). The recipients were divided into four groups: group I, single renal artery with single anastomosis (n = 890, 75.0%); group Il, multiple renal arteries, single anastomosis (n = 26, 2.2%); group Ill, multiple renal arteries, multiple anastomoses (n = 236, 19.9%); and group IV, polar artery ligation (n = 34, 2.9%). We compared the following variables patient and graft survivals; mean creatinine levels at 1 and 6 months, as well as 1-, 3-, and 5-years posttransplant; the number of acute rejection episodes, and the rates of vascular and urologic complications. The creatinine values and incidences of acute rejection episodes did not differ significantly (P = 0.399 and P = 0.990, respectively). There were no significant differences among the four groups in graft survival (P = 0.951), patient survival (P = 0.751), incidence of vascular (P = 0.999) or urologic complications (P = 0.371). The four groups were subdivided according to the recipient arterial anastomosis to the main graft renal artery. The subdivided groups showed no significant differences in graft or patient survival, or complications rates. The results indicated that multiplicity of renal arteries in kidney transplantation did not adversely affect allograft or patient survival compared with single renal artery transplantation. Moreover, the type of the arterial anastomosis (main renal artery end-to-end anastomosed to internal iliac artery or end-to-side anastomosed to external iliac artery appeared to not affect graft or patient survival or the incidence of vascular or urologic complications.  相似文献   

19.
肾移植术中移植肾缺血的处理(附4例报告)   总被引:1,自引:0,他引:1  
目的:探讨肾移植术中移植肾缺血的原因、预防措施及再灌注处理方法。方法:对移植术中移植肾缺血4例,分别采用离断肾动、静脉,离体灌注或切开肾静脉,离断肾动脉,原位灌注和肾动脉再与髂内动脉吻合方法处理。结果:4例患者术后移植肾功能恢复良好。随访3~15个月,每天尿量1500~3000ml,血肌酐均在正常范围,高血压均有不同程度缓解。结论:移植术中移植肾缺血在排除超急排斥原因后,原因未明或不能迅速纠正,应果断重新吻合血管,行移植肾再灌注。为防止髂外动脉成角导致移植肾缺血,髂外动脉不宜游离过长,以4cm左右为宜。  相似文献   

20.
复杂性肾动脉瘤诊治   总被引:1,自引:1,他引:0  
目的 探讨复杂性肾动脉瘤(RAA)的特点及诊治方法.方法 1999年3月至2008年9月收治复杂性RAA患者5例.女4例,男1例.平均年龄35(20~54)岁.腰痛伴血尿2例、腹痛伴休克i例、高血压1例、查体发现1例.RAA直径平均3.5(0.5~9.0)cm.单侧3例、双侧2例.5例均经数字减影血管造影确诊.保守治疗1例、肾动脉栓塞后肾切除1例、超选择性肾动脉栓塞1例、覆膜支架介入治疗1例、肾分支动脉结扎1例.结果 1例孤立肾多发动脉瘤破裂出血者保守治疗5 d死亡;1例肾上极1.5 cm动脉瘤,超选择性肾动脉栓塞后随访10个月未见复发;1例直径9.0 cm肾动脉瘤经肾动脉栓塞后行肾切除,随访12个月未见复发;1例肾内3.0 cm动脉瘤行覆膜支架介入治疗,随访12个月未见复发;1例右肾2.5 cm动脉瘤行右肾分支动脉结扎,10个月后发现左肾1.3 cm动脉瘤.随访24个月左肾RAA无变化,右肾RAA无复发.结论 直径<2 cmRAA可密切观察,复杂性RAA治疗应根据患者一般状况、症状,动脉瘤大小、数目、部位、肾功能、有无并发症等选择手术或介入治疗.  相似文献   

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