共查询到20条相似文献，搜索用时 15 毫秒
1.
Gulsum Uysal Fulya Cagli Hatice Akkaya Hakan Nazik Cigdem Karakukcu Serap Sutbeyaz Esra S. Yilmaz 《Journal of the Chinese Medical Association》2018,81(7):619-622
Background
Hyperemesis gravidarum (HG), related to protracted vomiting and nausea, is a common cause of hospitalization during the first trimester of pregnancy. It can be accompanied by ketonuria, dehydration, and weight loss. Our aim was to investigate bone loss in patients with HG.Methods
In our study, we investigated decreased bone mineral density (BMD)in a total of 79 patients (40 HG and 39 control) by means of dual energy X-ray absorptiometry (DEXA) measurements and laboratory parameters related to HG. All patients received DEXA measurement during the early postpartum period (usually two days after delivery, prior to discharge).This study was registered in the database via the Protocol Registration and Results System (PRS) (NCT03127293).Results
There was no significant difference in DEXA results (lumbar spine and total hip) and laboratory parameters between case and control groups, although a significant difference in vitamin intake was identified between cases and controls (65% vs. 92%, respectively, p = 0.003). Except for low serum levels of vitamin D, other laboratory parameters were in normal range in both groups.Conclusion
Pregnancies complicated by HG did not have decreased bone mineral density compared to those without HG. There is no evidence to relate HG to future osteoporosis. 相似文献2.
Mi Hye Kim Haesu Lee You Yeon Choi Dae Hoon Lee Woong Mo Yang 《Journal of the Chinese Medical Association》2018,81(2):141-146
Background
Scutellaria baicalensis (SB) is widely used as a medicinal plant to treat various inflammatory diseases. In the present study, we investigated the effects of SB on periodontitis in ligature-induced experimental rat model.Methods
Rats were subjected to a ligature placement around the first molar of the mandible to induce periodontitis. 100 mg/kg SB extracts were orally administered for 14 days. The molar tissues were stained with 1% methylene blue. Histopathological changes of the periodontium were observed by hematoxylin and eosin staining. The levels of cytokines were measured in the gingival tissue.Results
Alveolar bone resorption was statistically lower in the SB group compared to the ligatured group. SB inhibited the mineralization of cementum. In addition, SB reduced the production of IL-1β, 6, -8 and TNF-α cytokine mRNA expression in gingival tissues.Conclusion
These results suggest that SB showed ameliorative effects in the ligature-induced periodontitis by inhibition of inflammatory cytokine expression. 相似文献3.
Nazim Bozan Halit Demir Tülay Gürsoy Hüseyin Özkan Ufuk Düzenli Eren Sarıkaya Mahfuz Turan Ahmet Faruk Kiroglu Hakan Çankaya 《Journal of the Chinese Medical Association》2018,81(9):811-815
Background
Data describing how laryngeal cancer affects oxidative stress markers and antioxidants are limited. This study investigated serum antioxidant enzyme activities and oxidative stress markers before and after laryngectomies in patients with laryngeal cancer.Methods
A total of 29 patients with laryngeal cancer and 25 healthy control subjects were enrolled. Serum malondialdehyde (MDA) levels and superoxide dismutase (SOD), glutathione peroxidase (GSHPx), catalase (CAT), paraoxonase (PON), and arylesterase activities were measured spectrophotometrically. Blood samples were obtained from each patient just before surgery and 1 month after a laryngectomy.Results
The serum PON, arylesterase, CAT, SOD, and GSHPx activities were significantly decreased (all p < 0.001) and serum MDA levels were significantly increased (p < 0.001) in patients with laryngeal cancer, compared with control subjects. In laryngeal cancer patients, the serum GSHPx and arylesterase activity levels increased significantly following laryngectomies (both p < 0.001), whereas the MDA levels decreased significantly (p = 0.007).Conclusion
In patients with laryngeal cancer, the oxidant/antioxidant balance shifted toward oxidative stress. In addition, following laryngectomies, laryngeal cancer patients had increases in serum antioxidant enzyme activities and decreases in oxidative stress markers. 相似文献4.
Mei-Yung Tsou Jing-Yang Liou Chien-Kun Ting Shih-Pin Lin 《Journal of the Chinese Medical Association》2018,81(12):1071-1076
Background
Researchers have used logistic regression (LR) and non-linear response surface models (RSMs) to predict patient responses to sedation. The reduced Greco and hierarchy RSMs have proven to be more appropriate than other RSMs in gastrointestinal endoscopies using midazolam and alfentanil. In this study, we evaluate the performance of a simpler model, LR, and compared it with that of RSM.Methods
Thirty-three patients who received esophagogastroduodenoscopy (EGD) and colonoscopy sedation with midazolam and alfentanil were enrolled in the study. LR was performed for the EGD group and validated using the colonoscopy group. The two RSMs were performed using the same process, and performances and receiver operating characteristic (ROC) curves of the models were evaluated.Results
The native EGD LR model had an ROC curve area of 0.94. For external validation, the ROC curves were 0.92, 0.94, and 0.94 for the reduced Greco, hierarchy, and LR models, respectively. Pairwise comparison between models was not significant.Conclusion
The LR model performed as well as RSM in generalizing the predicted sedative effect of midazolam and alfentanil during gastrointestinal endoscopies. LR may be used for generalization across patients experiencing procedures with similar stimulus intensities. 相似文献5.
Pai-Han Wang Hui-Kuang Huang Jung-Pan Wang Yu-An Liu Yi-Chao Huang Ming-Chau Chang 《Journal of the Chinese Medical Association》2017,80(10):669-672
Background
Carpal tunnel release (CTR) is considered effective in treating carpal tunnel syndrome (CTS), and diabetes is considered to complicate the outcome and recovery. However, the difference in recurrence rate between diabetic and non-diabetic patients after mini-open CTR in the long-term has not yet determined.Methods
This study enrolled 1251 wrists (1091 patients), with 841 (67%) females and 480 (33%) males at a mean age of 58.5 years at operation. Patients were followed for a mean duration of 10.5 years. We retrospectively compared the recurrence rates of the Paine retinaculotome for mini-open CTR at wrist in diabetic and non-diabetic patients.Results
In our study, a total of 161 wrists (13%) were in the diabetic patients and 1090 wrists (87%) were in the non-diabetic patients. Two wrists (1.24%) in the diabetic group and seven (0.6%) in the non-diabetic group exhibited recurrence (p = 0.325).Conclusion
The mini-open CTR with the Paine retinaculotome in diabetic patients didn't show significantly higher recurrence rate than that in non-diabetic patients in the long term. 相似文献6.
Yang Yang Yun Feng Xu Chen Xiao-Nan Mao Jing-Han Zhang Li Zhao You-Yan Zhao Rui Cheng 《Journal of the Chinese Medical Association》2018,81(5):482-486
Background
There hasn't been conclusive proof about the association between vitamin D and pulmonary morbidities of prematurity.Methods
106 preterm infants were retrospectively included into this study. Clinical data and blood samples of all the patients were collected within 24 h of admission.Results
(1) Respiratory distress syndrome (RDS) patients were mainly concentrated in “≤30 weeks” stage when compared with other two gestational age groups. The only significant decrease of vitamin D concentration between RDS and non-RDS patients reflected in “≤30 weeks” stage (RDS vs. non-RDS: 29.48 ± 13.06 vs. 40.47 ± 20.52 nmol/l). (2) Bronchopulmonary dysplasia (BPD) patients were also concentrated in “≤30 weeks” stage. Vitamin D concentration showed significant difference both in “≤30 weeks” stage and “30–34 weeks” stage (≤30 weeks stage, BPD vs. non-BPD: 33.20 ± 16.51 vs. 39.21 ± 16.65 nmol/l; 30–34 weeks stage, BPD vs. non-BPD: 30.36 ± 15.50 vs. 41.21 ± 20.40 nmol/l). (3) Though vitamin D concentration in mechanical ventilation (MV) group was lower than non-MV group, there're no significant differences. (4) Vitamin D concentration in dead cases was significant lower than survival patients at discharge. (5) It showed a good correlation between vitamin D concentration and serum Ca, serum P, duration of MV and duration of oxygen support in “≤30 weeks” stage.Conclusion
The significant decrease of vitamin D concentration between RDS and non-RDS patients only reflected in “≤30 weeks” stage. And significant decrease of vitamin D concentration in BPD patients was both showed in “≤30 weeks” stage and “30–34 weeks” stage, which is consistent with “duration of oxygen support”. However, the overall effect did not show any difference in all preterm infants. It seems that the appropriate concentration of vitamin D is beneficial to lung maturation of human. Certainly, large sample, multi-center randomized controlled trials are necessary. 相似文献7.
Hsu-Dong Sun Huann-Cheng Horng Chia-Hao Liu Sheng-Mou Hsiao Yi-Jen Chen Wen-Hsun Chang Peng-Hui Wang 《Journal of the Chinese Medical Association》2018,81(5):469-474
Background
To compare the short-term outcome of patients undergoing single-port laparoscopic salpingectomy (SP-LS) and conventional three-port laparoscopic salpingectomy (C-LS).Methods
A retrospective evaluation of 112 patients with tubal pregnancies treated by one surgeon at a single teaching hospital. Among these, 47 patients were treated with SP-LS and the remaining 65 were treated with C-LS.Results
The characteristics of patients were similar in both groups. There were no statistically significant differences in operative time, estimated blood loss, intraoperative and immediate postoperative complications, and length of hospital stay between both groups. Time to bowel recanalization (6.2 ± 1.0 vs. 7.2 ± 1.4 h, p < 0.05) and postoperative visual analog scale for pain scores (3.0 ± 0.5 vs. 3.6 ± 0.6, p < 0.005) were significantly lower in the SP-LS group compared with those in the C-LS group.Conclusion
Our study demonstrated the feasibility to use the single-port laparoscopic salpingectomy in the management of women with tubal pregnancy, which showed the similar or better outcome compared with the use of conventional three-port laparoscopic salpingectomy. 相似文献8.
Raziye Desdicioglu Melahat Yildirim Gulcan Kocaoglu Busra Demir Cendek Gamze Avcioglu Emre Erdem Tas Ozlem Sengul Ozcan Erel Ayse Filiz Yavuz 《Journal of the Chinese Medical Association》2018,81(9):825-829
Background
The aim was to compare serum soluble urokinase-type plasminogen activator receptor (suPAR) levels as well as interleukin-6 levels (IL-6) in pregnant women with hyperemesis gravidarum (HG) and asymptomatic pregnant women.Methods
Our study population consists of voluntary first trimester-pregnant women who applied to the outpatient clinic of the department of obstetrics and gynecology of Ankara Ataturk Training and Research Hospital. Between February and May 2016, 60 pregnant women were included in our prospective study. Serum suPAR and IL-6 levels were evaluated with the ELISA method. Twenty-nine pregnant women with HG and 31 asymptomatic pregnant women were included in the study.Results
Serum suPAR level in the HG group was measured as 0.36 ± 0.56 ng/ml, whereas this level in the healthy pregnant control group was measured as 0.15 ± 0.15 ng/ml (p < 0.05). The interleukin-6 level in the HG group was 5.69 ± 2.16 pg/ml, whereas in the control group it was measured as 3.88 ± 0.28 pg/ml (p < 0.05).Conclusion
Serum suPAR and IL-6 levels proved to be high in the HG group. It is likely that suPAR could play a role in the etiopathogenesis of hyperemesis gravidarum. 相似文献9.
Huseyin Yesilyurt Berna Seckin Ayla Aktulay Sebnem Ozyer 《Journal of the Chinese Medical Association》2018,81(6):499-504
Background
Serum tumor markers are widely used for the preoperative evaluation of an adnexal mass. Elevations of cancer antigen (CA) 125 and CA 19-9 have been reported in patients with mature cystic teratoma (MCT). The aim of the study is to investigate the relation of serum tumor markers with tumor characteristics in young women with MCT.Methods
We conducted a retrospective review of 157 patients under the age of 35 who underwent laparoscopic surgery for ovarian MCT. Patients were divided into two age groups: Group I (n = 80): adolescents/young adults (aged 13–25 years) and Group II (n = 77): women aged 26–35 years. Data were analyzed for serum tumor markers, tumor size, and bilaterality.Results
The rates of elevated CA 125 and CA 19-9 were 10.7% and 31.5%, respectively, for Group I, and 13.9% and 26.5%, respectively, for Group II. The bilaterality rate was higher in Group II compared to Group I (19.5% vs. 8.8%, respectively, p = 0.04). Serum CA 125 and CA 19-9 elevations were not related to tumor size in Group I. In Group II, elevated levels of CA 125 were also unrelated to tumor size. However, significant elevation in CA 19-9 levels was observed when tumor size was larger than 4 cm in this age group (p = 0.004). Elevated CA 125 and CA 19-9 levels were not significantly associated with the presence of bilateral MCT in either group.Conclusion
The results of our study indicate that elevations of CA 19-9 are associated with larger tumor size in women aged 26–35 years, but not in adolescents/young adults. However, elevated serum CA 125 levels are not related to tumor size in either age group. 相似文献10.
Tsung-Hsing Chen Chen-Ming Hsu Hao-Tsai Cheng Yin-Yi Chu Ming-Yao Su Jun-Te Hsu Ta-Sen Yeh Chang-Fu Kuo Cheng-Tang Chiu 《Journal of the Chinese Medical Association》2018,81(12):1033-1037
Background
Esophagogastroduodenoscopy (EGD) is a standard tool for detection of mucosal and submucosal lesions. However, identification of Helicobacter pylori (H. P) infection using EGD alone is limited in accuracy. Linked color imaging (LCI) is a novel tool to capture real-time image with sufficient contrast to observe mucosal microstructure.Methods
This study aims to evaluate the applicability of LCI in the identification of H. pylori infection. Consecutive 122 patients scheduled for EGD were included. They were examined with LCI and magnifying endoscopy. The classification of H. pylori was based on pathology results of biopsy and rapid urease test or urea breath test.Results
We compared the results based on LCI or magnifying endoscopy to reference classification. Of 122 patients, 36 had H. pylori infection (29.51%). The level of accuracy of diagnosis of H. pylori infections by LCI, magnifying endoscopy, and both LCI and magnifying endoscopy was 78.38%, 81.98%, and 78.38%, respectively. The sensitivity and specificity of each group were 70.97%, 81.25%, and 80.65% and 82.5%, 83.87%, and 76.25%, respectively. The positive predictive values were 59.46%, 64.10%, and 57.78%, respectively, and the negative predictive values were 87.84%, 91.67%, and 92.42%, respectively.Conclusion
LCI could be playing a valuable initial screen tool for real-time diagnosis of H. pylori infections. It has a high accuracy of diagnosis of H. pylori infections. Therefore, in patients suspected to have H. pylori infections using LCI, the infections need to be carefully diagnosed using appropriate methods because, as per the consensus, they should be eradicated as soon as possible before precancerous lesions develop. 相似文献11.
Chien-Yu Huang Yaoh-Shiang Lin Yu-Hsi Liu Sheng-Chiao Lin Bor-Hwang Kang 《Journal of the Chinese Medical Association》2018,81(12):1060-1064
Background
The development of a hyperglycemic crisis in platinum-based chemotherapy-treated head and neck cancer patients, such as hyperosmolar hyperglycemic state (HHS), has been reported. Hyperglycemic crises are associated with a high risk of comorbidity and may delay cancer treatment if not promptly managed.Methods
This is a retrospective study using cancer registry data from a tertiary medical center. Head and neck cancer patients who had been treated with platinum-based chemotherapy from January 2014 to December 2015 were enrolled for review. Exclusion criteria included patients with a known history of type 2 diabetes mellitus (DM). Characteristics of patients who developed type 2 DM after initiation of chemotherapy were compared with non-DM patients, following which the clinical course of the patients developing a hyperglycemic crisis were reviewed.Results
A total of 185 patients were enrolled, of which seven patients (3.8%) had developed type 2 DM after initiation of platinum-based chemotherapy. No statistically significant differences in age, body mass index, sex, cancer subsite, cancer stage, or chemotherapy regimen were found when comparing new-onset type 2 DM patients with the rest of the patients. Three patients developed diabetic ketoacidosis, HHS, or impending HHS after initiating chemotherapy treatment. The incidence of hyperglycemic crises was 3 out of 185 (1.6%) in this patient group.Conclusion
Hyperglycemic crisis after cisplatin may be underestimated and may lead to a life-threatening condition. We suggest regular weekly follow-ups of serum glucose level after platinum-based chemotherapy for early detection of hyperglycemia and prevention of a life-threatening crisis. 相似文献12.
Po-Hui Lee Tu-Lai Yew Yu-Lin Lai Shyh-Yuan Lee Hen-Li Chen 《Journal of the Chinese Medical Association》2018,81(8):699-707
Background
Gene-activated matrix (GAM) induces sustained local production of growth factors to promote tissue regeneration. GAM contains a plasmid DNA (pDNA) encoding target proteins that is physically entrapped within a biodegradable matrix carrier. GAM with a pDNA encoding the first 34 amino acids of parathyroid hormone (PTH 1–34) and a collagen matrix enhances bone regeneration in long bone defects. Demineralized freeze-dried bone allograft (DFDBA) is a widely used osteoinductive bone graft. The present study determined the osteogenic effects of PTH-GAM with a collagen or DFDBA/collagen composite (D/C) matrix for treating craniofacial bone defects.Methods
We constructed a pDNA encoding human PTH 1–34 and performed cyclic AMP ELISA to verify the bioactivity of PTH 1–34. Next, we generated a D/C matrix and PTH-GAMs containing a collagen matrix (PTH-C-GAM) or D/C matrix (PTH-D/C-GAM). Rats with critical-sized calvarial bone defects were divided into four groups, namely, untreated rats (sham group) and rats grafted with D/C matrix, PTH-C-GAM, or PTH-D/C-GAM (D/C, PTH-C-GAM, or PTH-D/C-GAM groups, respectively). PTH expression was determined by performing immunohistochemical staining after 4 and 8 weeks. New bone formation was evaluated by performing radiography, dual-energy X-ray absorptiometry, microcomputed tomography, and histological examination.Results
PTH pDNA-transfected cells secreted bioactive PTH 1–34. Moreover, PTH was expressed at 4 and 8 weeks after the surgery in rats in the PTH-C-GAM group but not in rats in the D/C group. New bone formation in the calvarial bone defects, from more to less, was in the order of PTH-D/C-GAM, PTH-C-GAM, D/C, and sham groups.Conclusion
Our results indicate that PTH-GAM with a collagen matrix promotes local PTH production for at least 8 weeks and bone regeneration in craniofacial bone defect. Moreover, our results indicate that replacement of the collagen matrix with the D/C matrix improves the osteogenic effects of PTH-GAM. 相似文献13.
M. Dehdashtian M. Aletayeb A. Malakian M.R. Aramesh H. Malvandi 《Journal of the Chinese Medical Association》2018,81(2):183-186
Background
Transient tachypnea of the newborn (TTN) is a respiratory disorder secondary to inadequate or delayed clearance of lung fluids. Early symptoms of the disease are indistinguishable from neonatal respiratory distress syndrome, pneumonia, and persistent pulmonary hypertension. Therefore, these newborns, in addition to receiving conservative management, receive antibiotics until blood cultures provide definite results. In this study, we assessed the clinical course of neonates diagnosed with TTN who received conventional versus conservative management.Methods
One hundred and thirty neonates diagnosed as having TTN were randomly enrolled in two study groups. While patients belonging to one group received conservative management, those from the other group were treated with conventional medical therapy.Results
Mean duration of hospitalization was 7 ± 0.2 in the conventional and 5 ± 1.5 in the conservative group. Duration of antibiotic therapy was 6.7 ± 2.47 days in the conventional group.Conclusion
Newborns diagnosed with TTN without prenatal risk factors and a negative C reactive protein test do not need to be administered antibiotics and hospitalized until confirmatory blood culture results are obtained. 相似文献14.
Yaprak Engin Üstün Sema Sanisoğlu Mehmet Çınar Hüseyin Levent Keskin Dilek Uygur Ayşe Özcan Selma Karaahmetoğlu Aysun Kabasakal Gülşen Çolak Bekir Keskinkılıç İrfan Şencan 《Journal of the Chinese Medical Association》2018,81(11):985-989
Background
Our aim was to evaluate maternal mortality causes among Turkish women giving birth after assisted reproductive techniques (ARTs).Methods
All maternal deaths following conception with ART pregnancies were identified through the National Maternal Mortality Surveillance System. We analyzed the system data collected between 2007 and 2014. During this period, there were 10,369,064 live births and 1788 maternal deaths resulting from both direct and indirect causes. We identified 28 maternal death cases following ART procedures. The age, gestational age at birth, number of antenatal visits, delivery route, time of death, cause of death, and neonatal outcomes were recorded. Also, any existing delay (phase 1, 2, or 3) and preventability of maternal death were assessed.Results
Hypertensive disorders, pulmonary embolism, and cardiovascular disease were the leading causes of maternal death. Twelve (40%) women were over 35 years of age. Of the deaths, 15 (54%) were attributed to indirect causes. The number of unpreventable maternal deaths was 19 (67.9%), and 9 (36%) were classified as preventable after being assessed by the review commission of maternal mortality.Conclusion
Pregnancies conceived with ARTs should undergo a careful assessment of risk factors for hypertensive disorders, pulmonary embolism and cardiovascular diseases. Those women require closer antenatal surveillance because 1/3 of these deaths were preventable. 相似文献15.
Hsing-Ying Wu Heng-Sheng Chao Hsin-Chin Shih Chun-Che Shih Shi-Chuan Chang 《Journal of the Chinese Medical Association》2018,81(1):64-69
Background
When compared with open care model, a closed one improves patient care in intensive care units (ICUs), mixed ICUs, surgical ICUs and trauma centers. We wanted to evaluate the benefit of a collaborative care model in highly specialized cardiovascular care unit.Methods
This study was a retrospective, observational study conducted in the cardiovascular care unit of a teaching hospital. All patients who were above 20 years old and had received cardiovascular operation were enrolled for data collection and analysis.Results
A total of 270 subjects were enrolled for analysis during the 2-year study period. In the collaborative care model, the CVSU length of stay (p = 0.001) and CVSU-free days (p = 0.0008) were significantly better than those in an open care model.Discussion
The collaborative care model improved postoperative outcome in the cardiovascular surgical unit for those needing prolonged ICU care. 相似文献16.
Background
This study aims to evaluate the influence of nanoparticle size on the in vitro percutaneous penetration and retention and in vivo anti-inflammatory efficacy of percutaneously delivered non-steroidal anti-inflammatory drugs.Methods
Indomethacin, ketoprofen and piroxicam were incorporated into nanoparticles. The nanoparticles, or the bulk-drug equivalents, were suspended in a hydrophilic ointment and compared for their ability to facilitate percutaneous drug penetration and retention in vitro. The formulations were applied cutaneously in a carrageenan-induced footpad inflammation model (acute inflammation) and an adjuvant-induced arthritis model (chronic inflammation) in rats and were assessed for their anti-inflammatory efficacy and potency.Results
The nanoparticle formulations demonstrated a substantially smaller particle size compared with the bulk-drug formulations. The nanoparticles notably increased drug penetration and retention in vitro. In both the acute and chronic inflammation models, the nanoparticle formulations demonstrated significantly higher anti-inflammatory activity than that of their corresponding bulk-drug formulation at an equivalent dose, and produced better overall healing.Conclusion
The nanoparticle formulations are highly effective as percutaneous drug carriers, and demonstrate that decreasing particle size leads to increased efficacy and potency. The exploitation of such nanotechnology could drive the development of more effective percutaneous therapeutics. 相似文献17.
Che-Hung Liu Yen-Fang Tseng Jiun-I Lai Yin-Quan Chen Shih-Hao Wang Wei-Fong Kao Li-Hua Li Yu-Hui Chiu Chorng-Kuang How Wen-Han Chang 《Journal of the Chinese Medical Association》2018,81(5):475-481
Background
In endurance sports, stress, dehydration and release of chemical factors have been associated with red blood cell (RBC) alterations of structure and function, which may contribute to sports anemia, a well-observed phenomenon during long-distance running. Until now, the investigation of the changes of viscoelastic properties of RBC membrane, a decisive factor of RBC deformability to avoid hemolysis, is lacking, especially in an Oriental population.Methods
nineteen runners were prospectively recruited into our study. Hematological parameters were analyzed before and immediately after the 2015 Taipei 24H Ultra-Marathon Festival, Taiwan. Video particle tracking microrheology was used to determine viscoelastic properties of each RBC sample by calculating the dynamic elastic modulus G′(f) and the viscous modulus G″(f) at frequency f = 20 Hz.Results
Haptoglobin, RBC count, hemoglobin, hematocrit, mean cell hemoglobin, plasma free hemoglobin and unsaturated iron-binding capacity values of the recruited runners showed a statistically significant drop in the post-race values. Blood concentration of reticulocyte and ferritin were significantly higher at post-race compared with pre-race. 15 out of the 19 runners had a concurrent change in the elastic and the viscous moduli of their RBCs. Changes in the elastic and the viscous moduli were correlated with changes in the RBC count, hemoglobin and hematocrit.Conclusion
Viscoelasticity properties, the elastic modulus G′(f) and the viscous modulus G″(f) of RBCs are associated with endurance exercise-induced anemia. 相似文献18.
Shou-Wu Lee Han-Chung Lien Chi-Sen Chang Teng-Yu Lee Yen-Chun Peng Hong-Zen Yeh 《Journal of the Chinese Medical Association》2017,80(1):15-18
Background
Metabolic syndrome has been highlighted as a risk factor for several gastrointestinal diseases, including gastroesophageal reflux disease and Barrett’s esophagus (BE). The aim of this study was to investigate the association of metabolic syndrome with erosive esophagitis (EE) and BE.Methods
Data were retrospectively collected from patients who visited the Medical Screening Center at Taichung Veterans General Hospital, Taichung, Taiwan from January 2006 to December 2009. All patients underwent an open-access transoral upper gastrointestinal endoscopy, and serum laboratory data were collected. The exclusion criteria included prior gastric surgery, or presence of esophageal varices or peptic ulcers. These patients were assigned to groups according to their endoscopic findings as follows: (1) normal group; (2) EE group; and (3) BE group. Metabolic syndrome was diagnosed based on the International Diabetes Federation criteria.Results
There were 560/6499 (8.6%) patients, 214/1118 (9.6%) patients, and 19/95 (20%) patients with metabolic syndrome in the normal, EE, and BE groups, respectively. There was a significantly higher percentage of cases with hypertriglyceridemia in the EE group (67%) compared with the other groups. The BE group had significantly higher rates of central obesity (33%) and hypertension (29.5%) compared with rates in the normal and EE groups. After adjusting for confounders, the positive association with metabolic syndrome still existed in both the EE group (adjusted odds ratio = 2.43; 95% confidence interval = 1.02–3.44) and the BE group (adjusted odds ratio = 2.82; 95% confidence interval = 2.05–3.88).Conclusion
Our research indicated that in fact there is a greater risk of concurrent metabolic syndrome in patients with EE or BE. 相似文献19.
Hsin-Ting Lin Hui-Ju Chan Cheng-Wen Ho Ming-Cheng Tai Jiann-Torng Chen Chang-Min Liang 《Journal of the Chinese Medical Association》2018,81(11):998-1007
Background
The safety of Laser-assisted in situ keratomileusis (LASIK) in aircrew was unclear, in addition, LASIK was not yet approved for aircrew of Taiwan Air Force. This study was aimed to evaluate visual performance in LASIK eyes in hypoxic and twilight environment.Methods
48 myopic eyes of 24 subjects enrolled in this study were divided into LASIK group and control group. Subjects were exposed in hypoxic (15% O2) and mesopic (3 cd/m2) environment. Visual performance was evaluated using the Early Treatment of Diabetic Retinopathy Study (ETDRS) visual chart, and Functional Acuity Contrast Test (FACT) before and after the expirement. Physiological parameters of all subjects were measured and recorded throughout the experiment.Results
There was no significant difference of the two groups regarding their age, height, weight, and BMI. There is significant difference of preoperative spherical refractive error between the two groups. The results of physiological parameters were similar between two groups. Under normoxic conditions, there were no significant difference regarding distant vision in photopic and mesopic environments, so as for near vision. As a whole, the contrast sensitivity of the LASIK group were lowered than that of the control group about 35%, under whether normoxic or hypoxic conditions; photopic or mesopic circumstances. Under normoxic conditions, the measured accommodation of the LASIK group were 21% lowered than that of the control group and 31% lowered under hypoxic circumstances.Conclusion
There was no significant difference of visual acuity between the two groups regarding hypoxic and mesopic environment, but reduced contrast sensitivity was significant in LASIK group as compared to those of the control group. Accommodation was significantly lowered in LASIK group, compared with control group, in hypoxic environment. Whether postoperative visual performance after LASIK in aircrew during flying duty is safe might need further investigation. 相似文献20.
Shou-Wu Lee Han-Chung Lien Chi-Sen Chang Chung-Hsin Chang Chung-Wang Ko Hong-Zen Yeh 《Journal of the Chinese Medical Association》2018,81(10):860-864