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1.
女,60岁。因胆管癌4年余,咳胆汁样痰1月余入院。患者4年前因胆囊结石、肝内胆管结石在我院行胸腹联合切口剖腹探查术,术中行胆囊切除术、肝右叶切除术、胆总管探查胆肠吻合术,术毕行胸腔闭式引流和腹腔引流,术后诊断为肝右叶胆管扩张症并部分胆管癌变、肝内胆管巨大结石并肝右叶萎缩、胆管炎、胆囊炎。  相似文献   

2.
肝门部胆管癌指原发于左、右肝管及汇合部的恶性肿瘤,亦称肝外胆管上1/3癌,简称肝门癌。我院于1981年3月19日和7月1日为两例肝门癌患者进行了在肝叶,肝外胆管切除,右肝内胆管空肠吻合术。本文以其一例介绍手术方法.此例术前因进行性梗阻性黄疸进行了 ERCP 检  相似文献   

3.
患者女,78岁,因皮肤黄染就诊.超声检查见:肝脏大小正常,表面光滑,实质回声略不均匀,肝内2级胆管普遍扩张,左叶、右叶2级胆管内径0.3~0.5 cm,左右肝管内径1.2 cm ,胆总管上段内径1.6 cm.  相似文献   

4.
1临床资料 患者,女,32岁,因反复右上腹疼痛伴畏寒高热2年,于2012年12月8日入新余市人民医院。患者于2年前无明显诱因出现右上腹疼痛不适,并伴有畏寒高热,在当地医院行B超示:右肝内胆管结石并胆道感染,为进一步治疗收入本院肝胆外科。入院后行MR示:右肝后叶肝内胆管多发性结石并肝内胆管扩张,结石2 cm×3 cm大小,入院后完善相关检查后,行全身麻醉下右肝部分切除术(Ⅶ段),术后病理结果:右肝内胆管结石并胆管炎。  相似文献   

5.
目的 探讨超声监测重型肝炎患者门静脉右支前方肝内胆管超声表现的临床意义.方法 对57例接受住院治疗的重型肝炎患者进行超声监测,常规检查肝脏大小、门静脉血流动力学变化、胆囊及肝内胆管变化及腹腔积液等.观察治疗过程中57例重型肝炎患者肝内胆管回声变化和血总胆红素水平变化.结果 治疗过程中,57例重型肝炎患者中15例(15/57,26.3%)出现肝内胆管回声变化,42例(42/57,73.7%)肝内胆管回声无变化.肝内胆管回声变化组患者均表现为门静脉右支前方肝内胆管壁回声增厚、增强及管腔结构模糊不清,患者血总胆红素最高值的平均值为(457.8±141.1)μmol/L,明显高于肝内胆管回声无变化组患者的(299.9±116.1)μmol/L,且差异有统计学意义(t=3.89,P<0.05).肝内胆管回声变化组中12例病情好转患者肝内胆管回声变化逐渐消退,而3例死亡患者此声像改变持续存在.结论 治疗过程中超声监测重型肝炎患者门静脉右支前方肝内胆管回声变化对临床观察重型肝炎的治疗效果及判断预后有重要提示作用.  相似文献   

6.
患者女 ,5 4岁。 10年前在外院诊断慢性胆囊炎、胆石症行胆囊切除、胆总管探查取石 ,术后症状改善不明显。 8年前因右上腹反复疼痛伴畏寒、发热、巩膜黄染 ,做B超、CT检查显示肝右叶萎缩 ,肝内胆管多发结石、肝内胆管扩张。随后在我院行肝右叶部分切除 ,胆总管空肠Roux  相似文献   

7.
1 病例报告 患者男性,36岁,因反复右上腹痛伴畏寒、发热、黄疽5年于1993年5月2日入院。B超和CT均诊断为右肝叶多发性结石,胆囊炎。PTC示胆总管、右肝管扩张,右肝后叶胆管未显影,左肝内胆管显影无异常,Ⅰ级肝门位置右移Ⅱ度,上升二级,考虑有左肝肥大,右肝萎缩。于1993年6月21日全麻下剖腹。术中证实有左肝肥大,右肝萎缩,右肝后叶与膈面粘连,将粘连松解后,局部结石感明显。移除胆囊。  相似文献   

8.
黄沙  刘初平 《医学临床研究》2006,23(7):1083-1085
【目的】探讨肝切除治疗右肝内胆管结石的临床疗效及手术要领。【方法】对2002年10月至2005年9月52例因右肝内胆管结石行肝切除手术的临床资料进行回顾性分析。【结果】全组无手术死亡病例。随访6~35个月,术后效果优良率为81.8%,并发症发生率19%,经胆道造影残石率为9%。【结论】肝切术治疗右肝内胆管结石能取得比较好的临床效果,远期疗效明显。肝的充分显露、肝门阻断带的合理使用、肝切断平面的划定、残肝的正确处理是肝内胆管结石行肝切除手术的关键。  相似文献   

9.
在胆道外科中,胆囊动脉或肝动脉解剖变异并非罕见。然而,肝外胆管被肝动脉压迫却很少有报道。近年我院收治2例肝内胆管结石,其总肝管狭窄均系因右肝动脉压迫所致,报告如下。  相似文献   

10.
Caroli 氏病又称先天性肝内胆管扩张症,临床罕见,我院曾收治3例,报道如下。例1:女,11岁。因右上腹痛并发热5日入院。患者出生后7个月因先天性胆总管囊肿作囊肿十二指肠吻合术,术后2年反复发生右上腹痛及发  相似文献   

11.
This is a new method for the determination of creatine kinase isoenzyme MB activity in serum. The method uses direct activity measurement of creatine kinase B subunit activity after blocking of CK-M subunit activity by inhibiting antibodies. The test takes no longer than 15 min. The method yields an intra-serial C.V. of 2.0-12.9%, and a C.V. from day to day of 5.5%. The detection limit is 3.4 U/l creatine kinase MB. In the 95 cases with proven myocardial infarction several types of creatine kinase MB activity kinetics could be determined. The percentage of creatine kinase MB of peak CK-total is 6-25%, with a mean of 11.1%. The amount of creatine kinase MB with respect to total CK activity after reinfarction is higher than the amount after initial infarction.  相似文献   

12.
Ranganath C  Heller AS  Wilding EL 《NeuroImage》2007,35(4):1663-1673
Although substantial evidence suggests that the prefrontal cortex (PFC) implements processes that are critical for accurate episodic memory judgments, the specific roles of different PFC subregions remain unclear. Here, we used event-related functional magnetic resonance imaging to distinguish between prefrontal activity related to operations that (1) influence processing of retrieval cues based on current task demands, or (2) are involved in monitoring the outputs of retrieval. Fourteen participants studied auditory words spoken by a male or female speaker and completed memory tests in which the stimuli were unstudied foil words and studied words spoken by either the same speaker at study, or the alternate speaker. On "general" test trials, participants were to determine whether each word was studied, regardless of the voice of the speaker, whereas on "specific" test trials, participants were to additionally distinguish between studied words that were spoken in the same voice or a different voice at study. Thus, on specific test trials, participants were explicitly required to attend to voice information in order to evaluate each test item. Anterior (right BA 10), dorsolateral prefrontal (right BA 46), and inferior frontal (bilateral BA 47/12) regions were more active during specific than during general trials. Activation in anterior and dorsolateral PFC was enhanced during specific test trials even in response to unstudied items, suggesting that activation in these regions was related to the differential processing of retrieval cues in the two tasks. In contrast, differences between specific and general test trials in inferior frontal regions (bilateral BA 47/12) were seen only for studied items, suggesting a role for these regions in post-retrieval monitoring processes. Results from this study are consistent with the idea that different PFC subregions implement distinct, but complementary processes that collectively support accurate episodic memory judgments.  相似文献   

13.
14.
目的 探讨俯卧位通气对高海拔地区肺复张术(RM)治疗无效急性呼吸窘迫综合征(ARDS)患者的治疗作用.方法 从海拔2260m的地区医院筛选RM治疗无效的41例ARDS患者[平均氧合指数( PaO2/FiO2)较RM前升高<20%视为RM无效],依不同病因分为肺内源性ARDS组(ARDSp组)和肺外源性ARDS组(ARDSexp组),每组再按信封法随机分为俯卧位组和仰卧位组,即ARDSp俯卧位组(11例)、ARDSp仰卧位组(9例)、ARDSexp俯卧位组(10例)、ARDSexp仰卧位组(11例).在通气前及通气1、2、3、4h监测动脉血氧分压( PaO2)、PaO2/FiO2、静态顺应性(Cst)、气道阻力(Raw)的变化.结果 通气lh时,ARDSexp俯卧位组PaO2/FiO2( mm Hg,l mm Hg=0.133 kPa)即较通气前显著升高(157.4±40.6比129.3±48.7,P<0.05),并随通气时间延长呈持续增高趋势,4h达峰值(219.1 ±41.1);且ARDSexp俯卧位组通气3h内PaO2/FiO2较其他3组显著增高,另3组间则差异无统计学意义.ARDSp俯卧位组、ARDSexp俯卧位组通气4h时PaO2/FiO2均较相应仰卧位组显著增高(208.8±39.7比127.4±47.1,219.1±41.1比124.9±50.8,均P<0.05).4组通气前后Cst无显著改变,各组间差异也无统计学意义.ARDSp俯卧位组通气4h时Raw(cmH2O·L-1·s-1)较通气前显著降低(6.8±1.7比10.7±1.8,P<0.05),且明显低于其他3组;其他3组各时间点Raw组内及组间比较差异均无统计学意义.结论 俯卧位通气作为ARDS机械通气重要策略之一,可以改善RM无效高原ARDS患者的氧合,为抢救患者赢得宝贵的时间.  相似文献   

15.
The Department of Veterans Affairs (VA) in the USA operates a network of 172 medical centres which all utilize a hospital information system (HIS) which has been developed and is currently maintained by the VA. During the past several years, an image management and communication module has been developed, installed and clinically utilized at the Washington DC and Maryland VA Medical Centres. This image management and communication system, referred to as the decentralized hospital computer program (DHCP) imaging system, is fully integrated with a commercial picture archiving and communication system (PACS). The system is utilized to capture, archive, and display all images generated within the hospital including radiology, nuclear medicine, pathology, endoscopy, bronchoscopy, and dermatology, intraoperative photographs, ECG data, and a limited number of paper documents. The ultimate goal of the project is to have all patient text and image data available at any clinical workstation to any authorized user anywhere within the network of medical centres. Clinical requirements for an imaging workstation include ease of use, rapid and reliable access to the complete set of patient information, and images which are of acceptable quality to meet the requirements of the user and the subspecialty. Patient confidentiality and data security must be safeguarded at all times. Integration of the images with the remainder of the patient's database was found to be critical to the success of the project. The experience at the Washington and Maryland facilities suggests that an imaging system that is successfully integrated with a hospital information system can provide substantial clinical and economic benefits both within and among medical centres. Clinical acceptance and utilization of the system has been excellent, particularly in diagnostic radiology where DHCP Imaging has been interfaced to a commercial PAC system. Based upon this initial experience, the VA has begun to deploy the system throughout its large network of medical centres.  相似文献   

16.
17.
Myocardial elastography is a novel method for noninvasively assessing regional myocardial function, with the advantages of high spatial and temporal resolution and high signal-to-noise ratio (SNR). In this paper, in-vivo experiments were performed in anesthetized normal and infarcted mice (one day after left anterior descending coronary artery [LAD] ligation) using a high-resolution (30 MHz) ultrasound system (Vevo 770, VisualSonics Inc., Toronto, ON, Canada). Radiofrequency (RF) signals of the left ventricle (LV) in longitudinal (long-axis) view and the associated electrocardiogram (ECG) were simultaneously acquired. Using a retrospective ECG gating technique, 2-D full field-of-view RF frames were acquired at an extremely high frame rate (8 kHz) that resulted in high-quality incremental displacement and strain estimation of the myocardium. The incremental results were further accumulated to obtain the cumulative displacements and strains. Two-dimensional and M-mode displacement images and strain images (elastograms), as well as displacement and strain profiles as a function of time, were compared between normal and infarcted mice. Incremental results clearly depicted cardiac events including LV contraction, LV relaxation and isovolumetric phases in both normal and infarcted mice, and also evidently indicated reduced motion and deformation in the infarcted myocardium. The elastograms indicated that the infarcted regions underwent thinning during systole rather than thickening, as in the normal case. The cumulative elastograms were found to have higher elastographic SNR (SNR(e)) than the incremental elastograms (e.g., 10.6 vs. 4.7 in a normal myocardium, and 6.0 vs. 2.4 in an infarcted myocardium). Finally, preliminary statistical results from nine normal (m = 9) and seven infarcted (n = 7) mice indicated the capability of the cumulative strain in differentiating infracted from normal myocardia. In conclusion, myocardial elastography could provide regional strain information at simultaneously high temporal (>/=0.125 ms) and spatial ( approximately 55 microm) resolution as well as high precision ( approximately 0.05 microm displacement). This technique was thus capable of accurately characterizing normal myocardial function throughout an entire cardiac cycle, at the same high resolution, and detecting and localizing myocardial infarction in vivo.  相似文献   

18.
Delineating the Concept of Hope   总被引:2,自引:0,他引:2  
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19.
20.
Morphine, the most widely used mu-opioid analgesic for acute and chronic pain, is the standard against which new analgesics are measured. A thorough understanding of the pharmacokinetics of morphine is required in order to safely and effectively use this analgesic in a wide variety of patients with different levels of organ function. A MEDLINE search was conducted to identify literature published between 1966 and January 2002 relevant to the pharmacokinetics of morphine. These publications were reviewed and the literature summarized regarding unique and clinically important elements of morphine disposition relative to its parenteral administration (including intravenous, intramuscular, subcutaneous, epidural and intrathecal administration), absorption profile (immediate release, controlled release, and sublingual/buccal, and rectal administration), distribution, and its metabolism/ excretion. Special populations, including infants, elderly, and those with renal/liver failure, have a unique morphine pharmacokinetic profile that must be taken into account in order to maximize analgesic efficacy and reduce the risk of adverse events.  相似文献   

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