共查询到20条相似文献,搜索用时 31 毫秒
1.
Background
Elevated transient ischemic dilatation (TID) ratio during myocardial perfusion imaging (MPI) is described as a marker of severe CAD, even in acquisitions with normal perfusion. This was initiated to explore the effects of stressor type on the TID. Additionally the relation between the TID and other functional parameters, such as end diastolic volume (EDV), end systolic volume (ESV), and left ventricle ejection fraction (LVEF), heart rate (HR), and severity of ischemia, was evaluated. 相似文献2.
Hatt M Visvikis D Albarghach NM Tixier F Pradier O Cheze-le Rest C 《European journal of nuclear medicine and molecular imaging》2011,38(7):1191-1202
Purpose
18F-fluorodeoxyglucose (FDG) positron emission tomography (PET) image-derived parameters, such as standardized uptake value (SUV), functional tumour length (TL) and tumour volume (TV) or total lesion glycolysis (TLG), may be useful for determining prognosis in patients with oesophageal carcinoma. The objectives of this work were to investigate the prognostic value of these indices in oesophageal cancer patients undergoing combined chemoradiotherapy treatment and the impact of TV delineation strategies. 相似文献3.
François Harel Vincent Finnerty Jean Grégoire Bernard Thibault François Marcotte Patricia Ugolini Paul Khairy 《Journal of nuclear cardiology》2010,17(3):427-434
Background
We evaluated the accuracy of planar radionuclide angiography and different count-based and space-based electrocardiogram (ECG)-gated blood-pool single-photon emission computed tomography (GBPS) algorithms for assessment of left ventricular end-diastolic volume (LVEDV), end-systolic volume (LVESV), and ejection fraction (LVEF) compared with the gold standard of cardiac magnetic resonance imaging (cMRI). The goal is to assess the accuracy of a recently developed GBPS algorithm. 相似文献4.
Hirokazu Kudoh Sei Fujiwara Hideyuki Shiotani Hiroya Kawai Kenichi Hirata 《Annals of nuclear medicine》2010,24(5):379-385
Objective
Early diagnosis and initiating treatment of cardiac sarcoidosis are essential because cardiac involvement is an important prognostic factor. Although there are many reports on the diagnosis of cardiac sarcoidosis, the literature on predicting the efficacy of steroid therapy is very limited. The purposes of this study were to investigate the myocardial washout of 99mTc-tetrofosmin (TF), and to evaluate the predictability of left ventricular (LV) functional recovery after steroid therapy in patients with cardiac sarcoidosis. 相似文献5.
Hatt M Cheze Le Rest C Albarghach N Pradier O Visvikis D 《European journal of nuclear medicine and molecular imaging》2011,38(4):663-672
Purpose
Current state-of-the-art algorithms for functional uptake volume segmentation in PET imaging consist of threshold-based approaches, whose parameters often require specific optimization for a given scanner and associated reconstruction algorithms. Different advanced image segmentation approaches previously proposed and extensively validated, such as among others fuzzy C-means (FCM) clustering, or fuzzy locally adaptive bayesian (FLAB) algorithm have the potential to improve the robustness of functional uptake volume measurements. The objective of this study was to investigate robustness and repeatability with respect to various scanner models, reconstruction algorithms and acquisition conditions. 相似文献6.
Frick M Paetsch I den Harder C Kouwenhoven M Heese H Dries S Schnackenburg B de Kok W Gebker R Fleck E Manka R Jahnke C 《Journal of magnetic resonance imaging : JMRI》2011,34(2):457-467
Purpose:
To establish operator‐independent, fully automated planning of standard cardiac geometries and to determine the impact on interstudy reproducibility of cardiac functional parameters.Materials and Methods:
Cardiac MR imaging was done in 50 patients referred for left‐ventricular function assessment. In all patients, first standard manual planning was performed followed by automatic planning (AUTO1) and repeat automatic planning (AUTO2) after repositioning the patient to investigate interstudy reproducibility. Cardiac functional parameters were assessed and cine scans were visually graded on a 4‐point scale from nondiagnostic to excellent.Results:
Overall success rate of AUTO was 94% with good to excellent geometry planning in >94% of cine standard views. Comparing manual versus fully automated planning, a high agreement of cardiac functional parameters (Lin's concordance correlation coefficient, 0.91 to 0.99) with minimal percent bias (0.24 to 3.84%) was found. In addition, a high interstudy reproducibility of automatic planning was demonstrated (Lin's concordance correlation coefficient, 0.89 to 0.99; percent bias, 0.38 to 5.04%; precision, 3.46 to 9.09%).Conclusion:
Fully automated planning of cardiac geometries could reliably be performed in patients showing a variety of cardiovascular pathologies. Standard cardiac geometries were precisely replicated and functional parameters were highly accurate. J. Magn. Reson. Imaging 2011;. © 2011 Wiley‐Liss, Inc. 相似文献7.
Keiko Nemoto Masahiko Oguchi Masaru Nakajima Takuyou Kozuka Takayuki Nose Takashi Yamashita 《Japanese journal of radiology》2009,27(7):259-263
Purpose
The aim of this study was to evaluate the effect of decreasing the irradiated cardiac volume in breast-conserving therapy (BCT) using breath-adapted radiation therapy (BART). 相似文献8.
Guarise A Faccioli N Foti G Da Pozzo S Meneghetti P Morana G 《La Radiologia medica》2011,116(2):197-210
Purpose
Hypertrophic cardiomyopathy (HCM) is a hereditary disease characterised by primary hypertrophy of the left and/or right ventricle. The reference standard for imaging diagnosis is echocardiography. The aim of our study was to prospectively compare the diagnostic accuracy of echocardiography and cardiac magnetic resonance (MR) imaging in patients with HCM.Materials and methods
Twenty-two consecutive patients with a known diagnosis of HCM were prospectively evaluated, with echocardiography and cardiac MR imaging performed within 2 weeks of each other (mean interval 7 days, range 2?C14 days). Two experienced radiologists blinded to the previous clinical and imaging findings separately reviewed the images. The following parameters were calculated for both techniques: myocardial mass, wall thickness, end-diastolic volume (EDV), end-systolic volume (ESV), ejection fraction (EF), systolic anterior motion (SAM) of the mitral valve and degree of myocardial fibrosis (based on the ultrasonic reflectivity at echocardiography and degree of late enhancement at cardiac MR imaging). The statistical correlation was calculated with Student??s t test, Spearman coefficient and Fisher??s exact test. A value of p<0.05 was considered significant.Results
The diagnosis of HCM was confirmed in all patients with both techniques, with absolute agreement in terms of the site of disease. The mean value of myocardial mass presented a statistically significant difference between the two techniques (114 g, p<0.001). In contrast, a nonsignificant difference between echocardiography and cardiac MR imaging was found for EDV (102 ml vs 111 ml; p=0.31), ESV (30 ml vs 38 ml; p=0.1), EF (74% vs 68%, p=0.5), SAM (p=0.1) and myocardial fibrosis (p=0.15).Conclusions
Cardiac MR imaging correlates well with echocardiography in defining the morphological and functional parameters useful for the imaging diagnosis of HCM and therefore, in selected cases (poor acoustic window, doubtful echocardiography findings), it may be a valid alternative to echocardiography. 相似文献9.
Kuroiwa Y Nagamachi S Miyati T Yamaguchi K Nishii R Kuga N Azuma T Arita H Maeda M Tamura S Kawai K 《Annals of nuclear medicine》2012,26(2):147-163
Objective
The aim is to compare and evaluate the agreement of quantification of left ventricular functional parameters obtained by two different methods, 99mTc-tetrofosmin gated myocardial perfusion SPECT (MPS) and cardiac magnetic resonance imaging (CMR).Methods
Ten healthy male volunteers participated. Gated MPS data were acquired using 32 frames, which were also combined into 16- and 8-frame data set for the investigation. Gated CMR data were acquired using 8, 16 and 32-frame for the different sets. All examinations were conducted in resting and at exercise conditions. Quantitative measurements of end-diastolic volume (EDV), end-systolic volume (ESV), left ventricular ejection fraction (LVEF), peak ejection rate (PER), peak filling rate (PFR) and time to peak filling (TTPF) were done for each study, respectively. Finally, we evaluated the concordance of parameters between gated MPS and gated CMR by % difference and Bland?CAltman plot analysis.Results
LVEF showed favorable concordance in both rest and exercise conditions (% differences were around 10%). PER, PFR and TTPF also showed good concordances in rest conditions, under 32-frame gated collections particularly (% differences were around 10%). In exercise conditions, although the concordances were relatively good, certain variances were noted (% differences were around 20?C25%). Regarding left ventricular volumes, the concordance were worse in both conditions (% differences were around 30?C40%).Conclusions
In quantifying of left ventricular function parameter, gated CMR provides similar quantitative values comparing with gated MPS except for ventricular volumes in rest conditions. In contrast, there were certain variations except for LVEF in exercised examinations. When we follow patients by the same cardiac parameters with CMR and MPS, using parameters across the two modalities proved to be possible under rest condition. However, it is limited at exercise condition. 相似文献10.
Valverde I Parish V Tzifa A Head C Sarikouch S Greil G Schaeffter T Razavi R Beerbaum P 《Journal of magnetic resonance imaging : JMRI》2011,33(6):1341-1350
Purpose:
To evaluate the MR agreement of cardiac function parameters between volumetric (cine SSFP) and phase contrast flow (PC‐flow) assessment in patients with repaired tetralogy of Fallot (r‐TOF) and chronic pulmonary regurgitation (PR) at rest and under dobutamine stress (DS‐MR).Materials and Methods:
We studied 18 patients with r‐TOF and severe chronic PR (34 ± 12.7 years, PR fraction[flow] 44 ± 15%) by cardiac MR at rest, 10 and 20 μg/kg/min of dobutamine. We compared analogous functional parameters by volumetry and PC‐flow: (i) Systemic output [left ventricle stroke volume (LVSV) versus aortic forward flow (AOFF)], (ii) Pulmonary output [right ventricle stroke volume (RVSV) versus pulmonary forward flow (PAFF)], (iii) PR volume [(RVSV‐LVSV) versus pulmonary backward flow (PABF)], (iv) PR fraction [(RVSV‐LVSV/RVSV) versus (PABF/PAFF)].Results:
We found excellent Bland‐Altman agreement (mean difference ± limits of agreement, mL/beat/m2) at rest for both the systemic (?0.8 ± 5.7) and pulmonary strokes volumes (?0.1 ± 7.6), which slightly deteriorates during DS‐MR. The PR volume showed acceptable agreement at rest (?3.6 ± 15.1), but also further deteriorated during stress (5.4 ± 24). In contrast, the PR fraction showed poor agreement equally at rest (?5.6 ± 22.8) and DS‐MR (3.2 ± 19.2).Conclusion:
In r‐TOF with chronic PR, analogous functional parameters should not be used interchangeably between volumetric and PC‐flow assessment during DS‐MR evaluation. J. Magn. Reson. Imaging 2011;33:1341–1350. © 2011 Wiley‐Liss, Inc.11.
Luisa Muñoz del Romeral MD PhD Carol Stillson BA RVT Michael Lesh MD Elias Botvinick MD 《Journal of nuclear cardiology》2009,16(6):904-913
Background
The pacing site has been shown to influence functional improvement with cardiac resynchronization therapy. We evaluated the effects of the pacing site on left ventricular (LV) function in an animal model. 相似文献12.
Nasreddin Abolmaali Arne Koch Knut Götzelt Gabriele Hahn Guido Fitze Christian Vogelberg 《European radiology》2010,20(7):1580-1589
Objectives
To compare MRI-based functional pulmonary and cardiac measurements in the long-term follow-up of children operated on for left-sided congenital diaphragmatic hernia (CDH) with age- and body size-matched healthy controls. 相似文献13.
Andrés Server Bjørn A. Graff Tone E. Døli Orheim Till Schellhorn Roger Josefsen Øystein B. Gadmar Per H. Nakstad 《Neuroradiology》2011,53(6):435-447
Introduction
To assess the diagnostic accuracy of microvascular leakage (MVL), cerebral blood volume (CBV) and blood flow (CBF) values derived from dynamic susceptibility-weighted contrast-enhanced perfusion MR imaging (DSC-MR imaging) for grading of cerebral glial tumors, and to estimate the correlation between vascular permeability/perfusion parameters and tumor grades. 相似文献14.
R. Glenn Wells PhD FCCPM Brian Marvin BA MRT CNMT Gil Kovalski PhD Terrence D. Ruddy MD FRCPC FACC 《Journal of nuclear cardiology》2013,20(3):358-366
Background
We compared a dedicated cardiac camera with a traditional system for left ventricular (LV) functional measurements using gated blood-pool imaging.Methods
24-frame gated planar images were obtained from 48 patients in an LAO orientation for 6M counts/view on a standard gamma camera. Immediately thereafter, 24-frame ECG-gated data were obtained for 8 minutes on a dedicated cardiac SPECT camera. The gated SPECT image volumes were iteratively reconstructed and then transferred offline. In-house software was used to reproject the images into a 24-frame gated planar format. Both the original and the reprojected gated planar datasets were analyzed using semiautomated software to determine ejection fraction (EF), ventricular volume (end diastolic volume, EDV), peak ejection rate (PER), and peak filling rate (PFR).Results
The difference in EF values averaged 0.4% ± 4.4%. The correlation in EF was r ≥ 0.94 (P < .01) with a linear regression slope of 0.98. Correlation of the EDV was r ≥ 0.86 (P < .01), but the volumes from the dedicated cardiac camera were smaller (linear regression slope was 0.6). Correlation of PFR and PER were r = 0.91 and r ≥ 0.83, respectively (P < .01 for both).Conclusions
Reprojection of 24-frame gated blood-pool SPECT images is an effective means of obtaining LV functional measurements with a dedicated cardiac SPECT camera using standard 2D-planar analysis tools. 相似文献15.
Background
The purpose of this study was to determine the feasibility of serial quantitative 2-deoxy-2-[18F]fluoro-D-glucose (FDG) positron emission tomography (PET) to monitor the response of cardiac sarcoidosis to treatment.Methods and Results
A total of 38 PET scan intervals (54 PET scans) were obtained in 16 patients with cardiac sarcoidosis who underwent serial FDG PET during treatment. FDG-avid lesions of the heart were interpreted quantitatively using 4 PET parameters: maximum standardized uptake value (SUVmax), partial volume corrected mean standardized uptake value (SUVmean), partial volume corrected metabolic volume product (MVP), and global metabolic volume product (gMVP). Clinical response to treatment (improved, stable, or progressive disease) was evaluated by clinical symptoms, NYHA class, and EKG in all the patients. SUVmax, SUVmean, MVP, and gMVP had significantly decreased value on repeat PET in patients who were either stable or showed clinical improvement between two serial PET scans, while none of them had significant change on repeat PET in patients who were clinically worse. Correlation analysis between PET findings and clinical assessment revealed that the changes of SUVmax and SUVmean on repeat PET were negatively correlated with patient’s clinical outcome.Conclusion
Our results indicated that serial FDG PET is feasible to determine the extent of disease activity and to quantitatively assess the response of cardiac sarcoidosis to therapy.16.
Ichiro Nakae Hideki Hayashi Tetsuya Matsumoto Kenichi Mitsunami Minoru Horie 《Annals of nuclear medicine》2014,28(8):812-823
Objective
To investigate clinical usefulness of a novel program “Heart Function View (HFV)” for evaluating left ventricular (LV) function from myocardial perfusion SPECT (MPS), we compared LV functional parameters (F(x)) calculated by HFV with those obtained by the other similar programs QGS and cardioGRAF or by ultrasound echocardiography (UCG) and examined their correlations with clinical markers of heart failure: plasma BNP concentrations (BNPs) and exercise capacity.Methods
Studied patients (n = 60) underwent technetium-99m tetrofosmin quantitative gated MPS including treadmill exercise for examining heart disease. Myocardial stress images were acquired 30 min after the first tracer injection during maximal exercise. Three hours later, the second tracer was injected, and resting images were acquired. LV systolic F(x) [ejection fraction (EF), peak ejection rate (PER)] and diastolic F(x) [first third filling fraction (1/3FF), first third filling rate (1/3FR), peak filling rate (PFR), time to PFR (TPF)] were analyzed, and phase standard deviation (SD) and histogram bandwidth were obtained by phase analysis.Results
LV end-diastolic volume (EDV), end-systolic volume (ESV) and EF obtained from HFV were well correlated with those from QGS, cardioGRAF and UCG. A diastolic parameter Doppler E/e′ from UCG was significantly with PFR from HFV. There were good correlations between LVEDV, LVESV, LVEF, PER, PFR, 1/3FR, TPF and 1/3FF from HFV and those from cardioGRAF. LVEF, PER, 1/3FR, and PFR were significantly correlated with plasma BNP concentrations. In patients with non-ischemic heart disease (n = 42), phase SD and histogram bandwidth were correlated negatively with exercise capacity or PFR.Conclusions
HFV-derived LVF(x) are correlated with LVF(x) from the other programs or UCG, or with the clinical markers of heart failure and are thus useful in the functional assessment for patients with heart disease. 相似文献17.
Kim A. Connelly MBBS PhD Jay S. Detsky PhD John J. Graham MBBS Gideon Paul MBBS Ram Vijayaragavan MD Alexander J. Dick MD Graham A. Wright PhD 《Journal of magnetic resonance imaging : JMRI》2009,30(4):771-777
Purpose
To determine the accuracy of multicontrast late enhancement imaging (MCLE) in the assessment of myocardial viability and wall motion compared to the conventional wall motion and viability cardiac magnetic resonance imaging (MRI) pulse sequences.Materials and Methods
Forty‐one patients with suspected myocardial infarction were studied. Patients underwent assessment of cardiac function with cine steady‐state free‐precession (SSFP), followed by late gadolinium enhancement (LGE) imaging using inversion recovery gradient echo scanning (IR‐GRE) sequence and MCLE. MCLE was compared to cine SSFP in the assessment of wall motion, ejection fraction (EF), left ventricular (LV) mass, LV end‐diastolic volume (EDV), and to IR‐GRE for measuring infarct size.Results
MCLE, IR‐GRE, and SSFP imaging demonstrated excellent agreement in the assessment of EF, LV infarct size, and LV mass (r > 0.95, P < 0.001 for all measures), as well as in the assessment of wall motion (κ statistic 0.75).Conclusion
MCLE provided coregistered images for the assessment of viability and wall motion without loss of accuracy in the assessment of quantitative cardiac parameters. MCLE provides accurate quantitative cardiac assessment with reduced scan times compared to the conventional sequences and thus may be used as an alternative to conventional cine SSFP and IR‐GRE imaging. J. Magn. Reson. Imaging 2009;30:771–777. © 2009 Wiley‐Liss, Inc. 相似文献18.
Santiago Aguadé-Bruix Guillermo Romero-Farina Gemma Cuberas-Borros Marta Milà-Lopez Virginia Pubul-Núñez Rosa Siurana-Escuer David García-Dorado Jaume Candell-Riera 《Journal of nuclear cardiology》2010,17(3):450-458
Aim
The aim of this study was to assess interassay reproducibility of myocardial perfusion gated-SPECT for calculation of end-diastolic volume (EDV), end-systolic volume (ESV), and left ventricular ejection fraction (LVEF) in patients with atrial fibrillation (AF). 相似文献19.
Young Jin Jeong Hye Joo Son Hyun Jin Yoon Do-Young Kang 《Annals of nuclear medicine》2016,30(8):572-578
Objective
We applied a simple isocontour volume-of-interest (VOI) method to analyze the whole striatum in an F-18 FP-CIT PET image and to investigate the usefulness of the method in differentiating healthy subjects from idiopathic Parkinson’s disease (IPD) patients and the correlation of the value of functional volume parameters with the motor symptoms in patients with IPD.Methods
Forty-three IPD patients and 23 age-matched healthy controls underwent F-18 FP-CIT PET. Using a dedicated workstation, VOIs for the whole striatum were drawn automatically with the gradient delineation method. The SUVmax, SUVmean, functional volume (FV), striatal volume activity (SVA), striatal-specific binding (SSB), and volume-specific uptake ratio (VSUR) were compared between the IPD patients and the normal subjects. In the IPD patients, the correlation between the clinical factor and the functional parameters was assessed.Results
The SUVmax, SUVmean, FV, SVA, SSB, and VSUR were significantly lower in the IPD patients than in the normal subjects. In the receiver operating characteristic analysis, those parameters had significant and good-to-excellent accuracy. In the patients with IPD, a moderate negative correlation was revealed between the SUVmax and H&Y stage, the SUVmean and H&Y stage, SVA and H&Y stage, the VSUR and H&Y stage, the FV and bradykinesia, and the SVA and bradykinesia.Conclusion
The functional volumetric analysis of the striatum based on simple isocontour VOI was a useful method of analyzing the F-18 FP-CIT PET image. Not only can it be easily applied in daily clinical practice, but it can also be used as a clinical parameter to discriminate IPD and to correlate it with the disease severity.20.
Christian Lücke Kathrin Schindler Lukas Lehmkuhl Matthias Grothoff Ingo Eitel Gerhard Schuler Holger Thiele Dietmar Kivelitz Matthias Gutberlet 《European radiology》2010,20(9):2074-2083