The healing foods pyramid: an integrative nutrition tool

The article presents the Healing Foods Pyramid, an integrative nutrition tool. It is intended for use as a concise yet comprehensive resource to support dietary recommendations for integrative medicine and conventional healthcare professionals, as well as individuals seeking optimal health. It is in use in all 50 states and seven countries. Current institutional applications include a guide to improving food offerings in schools and hospital cafeterias, an educational tool in public health campaigns geared toward increased knowledge of healthy eating in Native American populations, and a medical nutrition education tool included in several medical school curricula.The Healing Foods Pyramid, released March 7, 2005, is available as an interactive Web-based nutrition tool at www.med.umich.edu/umim. Laminated portable copies with accompanying serving size document are available from the Web site. The Healing Foods Pyramid is a dynamic tool intended to respond to and reflect current information as it becomes available. We welcome your input on content and use.     

The early years of single photon emission computed tomography (SPECT): an anthology of selected reminiscences

The origin of SPECT can be found in pioneering experiments on emission tomography performed approximately 50 years ago. This historical review consists of a compilation of first person recollections from nine trailblazing scientists who shaped the early years of SPECT instrumentation during the 1960s and 1970s.     

Genomic alterations in salivary gland carcinomas: an illustrated update

Since the publication of our review on genomic alterations in salivary gland tumours in Diagnostic Histopathology in 2020, there have been several major developments. In the United Kingdom, next generation sequencing (NGS) of several tumour types is now commissioned by the National Health Service (NHS) either by whole genome sequencing (WGS) of fresh tumours, or targeted NGS in formalin-fixed paraffin embedded (FFPE) tissue. The UK genomic test directory includes several key gene fusion tests in salivary tumours, including NTRK, MAML2, EWSR1 and MYB. These can aid the clinician not only in refining histopathological classification in challenging cases, but they also have important therapeutic implications for patients with recurrent disease or where standard-of-care management options have been exhausted. This review will provide a brief update, including newly described entities since the previous review (most notably microsecretory carcinoma), as well as illustrating the utility of genomic testing in salivary tumours using several recent examples from our clinical practice.     

The liberal arts physician.

The United States is in the midst of the second revolution in American health care to occur during this century, as Kenneth Ludmerer makes clear in his book Time to Heal: American Medical Education from the Turn of the Century to the Era of Managed Care. The "Flexnerian revolution" eventually led to the closing of a third of the medical schools. Although such closures are not likely this time, familiar arrangements are collapsing, without a clear picture of the shape of things to come. Whatever the outcome of the current revolution, well-trained physicians will be needed to care for the sick. Academic medical centers truly are at risk and increasingly require public support to flourish or even to survive, but medical schools and their teaching hospitals must demonstrate that they deserve this support. These institutions have responded by focusing on the business aspects of medicine, perhaps to the detriment of medical education. Lost in this focus is teaching time, and perhaps even more important, the time for mentoring. Often lacking too is a clear vision of the preparation needed by the student to practice medicine successfully in the future: different specialty mixes, interdisciplinary group practice; vastly increased use of information technologies, and overwhelming amounts of relevant and interrelated information. Yet the answer is the same as it was 75 years ago when Yale introduced the first radical medical curricular reform--the "liberal arts physician," trained in science, the values of medicine, and particularly for uncertainly and with the capacity to adapt.     

The Oxford Grid

The 'Oxford Grid' is a term used to denote a method of displaying homologous loci from two species. It may also be used as a basis for historical inferences relating to co-ancestry. These uses are discussed with special reference to man and mouse. It is inferred that as few as 30 reciprocal translocations are sufficient to explain the differences defined by the present grid and that the telocentric karyotype, through which the mouse differs from both man and many closely related rodents, including the rat, must have evolved mainly through the formation and suppression of centromeres rather than through pericentric inversions. Mouse and man share the widest distribution of any mammal and their success appears to be related to being omnivorous with behavioural modifications allowing a wide range of habitat.