双源CT与超声心动图评估左心功能的比较研究

目的：比较双源CT（Dual—source CT,DSCT）和超声心电图对左心功能的评估,探讨DSCT在定量评估左心功能方面的;住确性及可行性。方法：对31例临床确诊或疑似冠状动脉粥样硬化心脏病患者行双源CT冠状动脉成像和超声心电图检查．分别测得左心室收缩末期容积、舒张末期容积及左室射血分数值,并进行统计学分析。结果：双源CT和超声心电图所测得的各组左心功能数据相关性高（r值=0．70～0．87）。结论：双源CT冠状动脉成像检查不但可以分析冠状动脉疾病．同时也可以定量评估左心功能。     

64层CT冠状动脉造影和左心功能分析预测急性心肌梗塞风险的初步研究

目的探索64层CT冠状动脉造影和左心功能分析进行冠心病急性心肌梗塞风险预测的作用和价值。方法对289例64层CT冠状动脉造影和左心功能资料进行回顾性分析。按照冠状动脉管腔狭窄程度以及斑块的种类将受检者分为4组:Ⅰ,管壁光整或呈环形增厚,管腔狭窄<30%;Ⅱ,管壁偏心性增厚或单发钙化斑块,管腔狭窄<50%;Ⅲ,单或多发软斑块,管腔狭窄<50%;Ⅳ,多发软斑块或多发混合性斑块,管腔狭窄>50%。按组别分别计算左心室功能指标的平均值,进行统计学分析并与临床资料对照。结果LVMM,LVEDV与临床证实的心肌缺血发生率间呈正相关(r≈0.82,0.76)。LVEF与临床证实的心肌缺血发生率间呈负相关(r≈-0.74)。结论仅依据冠状动脉狭窄程度无法准确预测冠心病急性心肌梗塞风险。运用64层CT冠状动脉造影和左心功能分析能够同时显示冠状动脉的狭窄程度和斑块类型以及心脏功能改变,在冠心病急性心肌梗塞风险预测中具有更大意义。     

心率对64层螺旋CT左室射血分数测定的影响

目的：通过比较64层螺旋CT和超声心动图在不同心率时对左室射血分数（LVEF）的测量结果,初步探讨心率对64层螺旋CT测定LVEF的影响。方法：对107例临床怀疑或确诊冠心病的患者行64层螺旋CT检查,采用心功能分析软件进行后处理,计算左室收缩末期容积（ESV）、左室舒张末期容积（EDV）及LVEF,并与超声心动图的测量结果进行对比分析。入选患者按照心率分为3组：A组为心率≤65次/分,B组为心率66～75次/分,C组为心率〉75次/分。结果：64层CT和超声心动图所测LVEF分别为0.6963±0.0757和0.6998±0.0761,两组测量值有很好的相关性（r=0.962,P〉0.05）;在不同心率下两种检查方法对评价LVEF也具有较好的相关性（A、B和C组的r值分别为0.977、0.967和0.883,P〉0.05）。结论：64层螺旋CT冠状动脉成像在对冠脉病变进行诊断的同时还可用于评价左心室功能。     

64层螺旋CT对心肌桥与冠状动脉粥样硬化相关性的评价

目的：利用64层螺旋CT评价左冠状动脉前降支心肌桥（MB）与该支冠状动脉粥样硬化的相关关系。方法：连续收集300例因怀疑冠心病（CHD）而行64层螺旋CT冠状动脉血管成像（CTA）的病例的资料,由2名CT诊断医师独立判断并在结果一致时确定为前降支MB。将所有病例分为前降支MB组和非MB组,利用MPR、CPR、VR等后处理技术联合观察左冠状动脉前降支钙化及粥样硬化斑块的总体发生率,测量前降支由于斑块所致的狭窄率,比较MB组与非MB组的平均狭窄程度以及钙化、粥样硬化斑块的总体发生率。结果：在300例受检对象中冠状动脉CTA发现前降支MB74例（24.7%,74/300）。MB组与非MB组前降支钙化的发生率分别为36.5%与31.3%,粥样硬化斑块的发生率分别为54.1%与45.1%,MB组与非MB组的平均狭窄程度分别为48.4%与44.6%,两组之间钙化的发生率、粥样硬化斑块的发生率及平均狭窄程度差别均无明显统计学意义（P=0.40;P=0.18;P=0.97）。结论：左冠状动脉前降支MB对该支冠状动脉狭窄程度及粥样硬化斑块的总体发生率影响不明显。     

超声心肌做功技术对左前降支狭窄患者左心室收缩功能的诊断价值

目的 探讨采用超声心肌做功技术评价左前降支（LAD）狭窄患者左心室收缩功能，及各参数对LAD狭窄的诊断效能。资料与方法 前瞻性收集2019年10月—2021年3月哈尔滨医科大学附属第四医院疑似诊断为冠心病并拟行冠状动脉造影的患者249例，于冠状动脉造影前3 d内行超声心动图检查，根据冠状动脉造影LAD狭窄程度，分为对照组（无狭窄）、轻度组（0<狭窄程度≤50%）、中度组（50%<狭窄程度<75%）和重度组（狭窄程度≥75%），每组均筛选30例符合超声检查入选标准、无器质性病变及其他检查禁忌证的患者纳入研究，分析临床资料，常规超声参数，左心室整体纵向应变，心肌做功参数包括整体做功指数、整体有效功、整体做功效率（GWE）和整体无效功，采用受试者工作特征曲线分析各参数对LAD中、重度狭窄的诊断价值。结果 4组患者性别、年龄、高血压及糖尿病患病情况、接受药物治疗情况和常规超声参数左心房内径、左心室舒张末期内径和容积、收缩末期内径和容积、左心室射血分数、舒张期二尖瓣口流速、E/e’差异均无统计学意义（P均>0.05）。4组整体纵向应变、整体做功指数、整体有效功、GWE、整...     

64层螺旋CT诊断心肌桥-壁冠状动脉的相关性研究

目的：探讨64层螺旋CT诊断心肌桥-壁冠状动脉（MB-MCA）的相关性研究。方法回顾154例MB-MCA患者的影像资料,用双时相冠状动脉重建结合多平面重建（MPR）、容积再现（VR）、最大密度（MIP）投影技术测量MB-MCA,对比分析其结果、临床症状及心电图ST-T改变的差异。结果 MB-MCA多发生于前降支（116例占75．3％）,MB厚度0．51-4．6 mm,平均1．25 mm。长为1．2-5．1 mm,平均2．47 mm。其中75％时相MCA狭窄106段,狭窄程度25％-65％;45％时相MCA狭窄154段,狭窄程度32％-82％。48例未见血管硬化及狭窄征象;106例管腔伴有不同程度的粥样硬化斑块和狭窄,以前降支近段、中段多见。管腔狭窄＜50％者126例（81．8％）;钙化斑块伴狭窄＜50％36例、≥50％12例;软斑块23例狭窄＜50％;混合斑块35例（其中狭窄＜50％20例、≥50％15例）。不同时相管腔狭窄程度与临床症状、心电图ST-T段改变有明显相关性。结论64层CT双时相重建对MB-MCA检出率高,但仍有一定局限性,对不同心动周期时MB-MCA的动态变化不了解。 MB发生部位、厚度与临床症状、心电图ST-T改变有一定的相关性,与MCA长度可能无明显相关。     

多层螺旋CT对原发性高血压病心功能相关性研究

目的应用64层螺旋CT对原发性高血压病心功能进行评估,探讨其主要CT表现。方法高血压病例127例,按世界卫生组织高血压诊断标准将其分为高血压Ⅰ、Ⅱ、Ⅲ级组。正常对照组21人。均行多层螺旋CT心脏成像扫描,经心脏分析软件包处理后分别计算出体表面积、左室射血分数、左室舒张末期容积、左室收缩末期容积、每搏输出量、心指数、左室心肌质量等参数,并进行统计学分析。结果高血压病Ⅰ级组46例主要为心肌肥厚改变(P<0.05),高血压病Ⅱ级组38例逐步出现心肌几何构形重构,高血压Ⅲ级组43例心脏离心性重构,心功能减低,左室舒张及收缩末期容积升高,射血分数、每搏输出量、每分输出量、心指数均减低(各组均P<0.05)。结论原发性高血压病心脏改变是从向心性重构到离心性重构,从心功能代偿到失代偿动态过程;64层CT可全面客观评价原发性高血压病心脏功能。     

多层螺旋CT冠状动脉血管成像时心肌桥的检出与临床价值

目的探讨多层CT冠状动脉血管成像检查患者中心肌桥的特征及临床意义。方法临床确诊冠心病或疑似冠心病而行多层螺旋CT冠状动脉血管成像检查的病例875例,男579例,女296例,年龄30~87岁,平均60岁。采用回顾性心电门控扫描,心率>75次/min,重建相位区间为30%～40%,心率<75次/min,重建相位区间为40%～50%,获得最大密度投影、曲面重组、容积重组图像,从多角度显示左、右冠状动脉主干及其各主要分支。结果检出89例心肌桥患者,检出率10.2%。其中36例(40.5%)管腔呈不同程度的狭窄(<50%)。发生于前降支中段者71例(79.8%),肌桥厚度0.06～0.55cm,其中20例近段伴有不同程度的粥样硬化斑块,管腔狭窄均接近50%。单纯心肌桥患者有心绞痛症状者39例,心肌桥伴有冠状动脉粥样硬化者有心绞痛症状23例。结论MSCT冠状动脉血管成像可以明确检出心肌桥,为临床的诊断和治疗提供了更具价值的信息。     

64层螺旋CT诊断冠状动脉不同程度狭窄的临床价值

目的 用传统的冠状动脉造影作对照,评价64层螺旋CT诊断冠状动脉不同程度狭窄的准确性与一致性.方法 78例患者临床怀疑冠心病并同期接受64层螺旋CT冠状动脉成像及常规冠状动脉造影,计算64层螺旋CT检测冠状动脉严重狭窄(管腔狭窄＞75%)、中等度狭窄(管腔狭窄＞50%)和轻度狭窄(管腔狭窄≤50%)的敏感性、特异性、阳性预测值、阴性预测值.按图像质量(4分法)对冠状动脉节段进行分组,探讨图像质量对64层螺旋CT诊断冠状动脉狭窄的影响.定性与定量比较64层螺旋CT与QCA诊断冠状动脉狭窄的一致性.结果 64层螺旋CT检测冠状动脉狭窄总体敏感性、特异性、阳性预测值、阴性预测值分别为:93.4%、97.9%、88.3%、98.9%.诊断严重、中等度及轻度冠状动脉狭窄的敏感性为81%、59%、75%,特异性为98%.64层螺旋CT能够显示的冠状动脉节段有999段,图像质量为4分的有17段.64层螺旋CT与QCA诊断冠状动脉狭窄一致性的Kappa值=0.7856,P<0.01,两者一致性有统计学意义.相关系数r=0.661,P<0.01,具有正相关关系.结论 64层螺旋CT是一种有效的无创性的检测冠状动脉狭窄的工具.其与QCA诊断冠状动脉不同程度狭窄具有正相关关系.     

64层CT评价心外膜脂肪组织与冠状动脉狭窄程度的相关性

目的：采用64层MSCT评价心外膜脂肪组织厚度（EAT）与心外膜脂肪组织容积（EAV）和冠状动脉狭窄程度的关系。方法：临床拟诊为冠心病（CAD）的患者188例为研究对象,男114例,女74例,平均年龄（64.0±9.97）岁;均行心脏冠状动脉64层MSCT血管成像,在GE ADW4.4工作站分别测量左心室心尖部的脂肪组织厚度及全心外膜脂肪组织容积,并对冠状动脉狭窄程度进行定量Gensini积分。结果：本组病例共检出有冠状动脉病变的病例106例,病变178处,其中轻度狭窄组（管腔狭窄51%~75%）67例,病变125处;中度狭窄组（管腔狭窄76%~90%）21例,病变27处;重度狭窄组（管腔狭窄91%~99%）12例,病变18处;完全闭塞组（管腔狭窄100%）6例,病变8处。冠状动脉轻度、中度、重度狭窄及完全闭塞组之间的EAT和EAV差异均具有显著统计学意义（FT=32.306,FV=27.743,P=0.000）,四组之间Gensini积分差异均具有显著统计学意义（F=110.483,P=0.000）。冠状动脉狭窄的Gensini积分与EAT、EAV呈显著正相关（rT=0.739、rV=0.801,P=0.000）。结论：心外膜脂肪组织厚度、容积与冠状动脉狭窄程度呈显著正相关。     

64层螺旋CT在川崎病冠状动脉病变中的应用价值

目的探讨64层螺旋CT在川崎病冠状动脉病变中的应用价值。方法回顾性分析川崎病20例,所有患者均行64层螺旋CT冠状动脉造影和彩色多普勒超声检查,并对伴有冠状动脉病变患儿进行随访。结果典型川崎病患者15例,其中9例CT和彩色多普勒超声冠状动脉检查均未见异常,5例显示相同(2例左、右冠状动脉扩张,2例冠状动脉瘤形成,1例巨大动脉瘤伴附壁血栓),1例CT示左、右冠状动脉中远段多发瘤样扩张,B超未见明显异常。非典型川崎病患者5例,其中3例CT和B超冠状动脉检查均显示相同(2例冠状动脉瘤,1例双侧冠状动脉增粗迂曲),2例B超未见异常,CT示冠状动脉均有病变(1例冠状动脉瘤,1例冠状动脉狭窄)。结论64层螺旋CT冠状动脉造影对川崎病冠状动脉病变的诊断和随访很有价值。     

Clinical application of 64-slice spiral CT in the diagnosis of the Tetralogy of Fallot

OBJECTIVE: To explore the clinical application of 64-slice spiral CT in the diagnosis of the Tetralogy of Fallot. METHODS: Eighteen patients with diagnosed Tetralogy of Fallot underwent cardiac CT angiography with 64-slice CT (CTA). Two- and three-dimensional images were used for diagnosing in all cases by means of MPR (coronal, sagital and oblique), cMPR, MIP and VRT. RESULTS: All patients had ventricular septal defect, pulmonary stenosis and hypertrophy of right ventricle. The morphologic features of Tetralogy of Fallot were equal to echocardiography. Patent ductus arteriosus (PDA) were detected on eight patients. Main coronary artery branches and partial sub-branches were visualized in all patients. Abnormal coronary arteries were found in seven cases: both left and right main coronary artery arising from the right aortic sinus one case, right main coronary artery and circumflex (CX) arising from the right aortic sinus one case, left anterior descending (LAD) and CX arising from left aortic sinus directly one case, left and right coronary artery arising from back and front of the aortic sinus, respectively, three cases. Pulmonary artery branch stenosis was found in 12 cases and branch pulmonary artery dilation noticed in 1 case. Double superior vena cava was also found in one case. According to the surgery the diagnostic accuracy of CT and Echocardiography was 95.45 and 83.33%, respectively. CONCLUSION: Two- and three-dimensional 64-slice CTA not only show the overall anatomical structure of the heart, but also show coronary and pulmonary arteries. With these results, evaluation of coronary anomalies and pulmonary artery stenosis with 64-MSCT is extremely valuable for planning the operative procedure on the patients with Tetralogy of Fallot.     

Comprehensive cardiac CT study: Evaluation of coronary arteries,left ventricular function,and myocardial perfusion—Is it possible?

With advances in multidetector computed tomography (MDCT) technology, the new generation of 64-slice MDCT scanners with submillimeter collimation and a faster gantry ratation allows imaging of the entire heart in a single breath-hold with excellent temporal and spatial resolution. This potentially permits a comprehensive assessment of coronary anatomy, left ventricular function, and myocardial perfusion. As will be seen in this review of the current literature regarding 16- and 64-slice MDCT, there is great promise for a comprehensive cardiac computed tomography (CT) study. The available data support the notion that CT coronary angiography may be an alternative to invasive coronary angiography in symptomatic patients with a low to intermediate likelihood of having coronary artery disease. By use of the same data acquired for CT coronary angiography, evaluation of global and regional left ventricular function and myocardial perfusion can be added to the MDCT evaluation without additional exposure to contrast medium or radiation and may provide a more conclusive cardiac workup in these patients. The potential applications and limitations of coronary stenosis detection, global and regional left ventricular function, and myocardial perfusion assessment by MDCT will be reviewed. The full potential of cardiac MDCT is just beginning to be realized.     

Assessment of global and regional left ventricular function using 64-slice multislice computed tomography and 2D echocardiography: a comparison with cardiac magnetic resonance

OBJECTIVES: To compare the assessment of global and regional left ventricular (LV) function using 64-slice multislice computed tomography (MSCT), 2D echocardiography (2DE) and cardiac magnetic resonance (CMR). METHODS: Thirty-two consecutive patients (mean age, 56.5+/-9.7 years) referred for evaluation of coronary artery using 64-slice MSCT also underwent 2DE and CMR within 48h. The global left ventricular function which include left ventricular ejection fraction (LVEF), left ventricular end diastolic volume (LVdV) and left ventricular end systolic volume (LVsV) were determine using the three modalities. Regional wall motion (RWM) was assessed visually in all three modalities. The CMR served as the gold standard for the comparison between 64-slice MSCT with CMR and 2DE with CMR. Statistical analysis included Pearson correlation coefficient, Bland-Altman plots and kappa-statistics. RESULTS: The 64-slice MSCT agreed well with CMR for assessment of LVEF (r=0.92; p<0.0001), LVdV (r=0.98; p<0.0001) and LVsV (r=0.98; p<0.0001). In comparison with 64-slice MSCT, 2DE showed moderate correlation with CMR for the assessment of LVEF (r=0.84; p<0.0001), LVdV (r=0.83; p<0.0001) and LVsV (r=0.80; p<0.0001). However in RWM analysis, 2DE showed better accuracy than 64-slice MSCT (94.3% versus 82.4%) and closer agreement (kappa=0.89 versus 0.63) with CMR. CONCLUSION: 64-Slice MSCT correlates strongly with CMR in global LV function however in regional LV function 2DE showed better agreement with CMR than 64-slice MSCT.     

多层螺旋CT定量评价左心室局部功能的可行性研究

目的:与3-DE对照,探讨多层螺旋CT冠状动脉造影所获得的数据,定量分析左心室局部功能的可行性及准确性。方法:选取临床拟诊或可疑冠心病患者20例,接受64-SCT冠状动脉造影检查后,1周内同时接受3-DE检查,使用设备自带心功能分析软件评价心功能。所有数据均以x±s形式表示,应用配对样本t检验及相关分析检验。结果:20患者采用64-SCT及3-DE两种方法测量乳头肌处左室前壁、侧壁、后壁及室间隔的EST、EDT厚度值,计算其增厚率,并进行配对t检验示左室前壁、侧壁、后壁及室间隔增厚率,差异无显著统计学意义(P>0.05);两种方法所得测量值均有较好的相关性(r分别为0.906,0.976,0.981,0.939),相关性检验有统计学意义,有显著差异性(P<0.05),散点图呈线性趋势。结论:64-SCT定量评价左心室局部功能具有可行性,其结果与3-DE高度相关;与其他影像学相比,64-SCT在一次冠状动脉造影检查的同时兼顾了形态学的显示与功能的分析。     

16层螺旋CT冠状动脉血管成像技术临床应用

目的:探讨16层螺旋CT冠状动脉成像技术临床应用价值。方法:对45例临床诊断或可疑冠心病的住院患者行16层螺旋CT冠状动脉回顾性心电门控平扫及增强扫描。将增强扫描图像传送到Wizard图像工作站进行最大密度投影(MIP)、多平面重组(MPR)、曲面重组(CPR)、容积再现技术(VRT)及平带多平面重组(RMPR)。并将VRT及MIP重组像为参照,用平扫图像对冠状动脉各支段进行钙化积分。结果:左冠状动脉主干(LM)、左前降支近中段(LAD1、LAD2)、第一对角支(D1)、左回旋支(LCX)及右冠状动脉近段(RCA1)显示均45例(100%),左前降支远段(LAD3)23例(51%),第二对角支(D2)30例(67%),第三对角支(D3)24例(53%),第一左缘支(M1)36例(80%),第二缘支(M2)28例(62%),右冠状动脉中段(RCA2)41例(91%),右冠状动脉远段(RCA3)43例(96%)及后降支(PDA)34例(76%)。左冠状动脉主干钙化12例(27%),左前降支近中段钙化有29例(64%),左回旋支钙化例数22例(49%),右冠状动脉近中段钙化有24例(53%)。结论:16层螺旋CT可对冠状动脉进行钙化积分并准确显影,是冠状动脉粥样硬化疾病筛选和诊断的首选方法。     

64MSCTA对冠状动脉变异的诊断及临床评价

目的评价64层螺旋CT冠状动脉血管成像（CTCA）对冠状动脉变异的诊断价值及临床评价。方法回顾性分析3529例临床疑为心肌缺血患者及常规体查者冠状动脉CTA影像检查结果并对发现的变异冠状动脉进行分类。结果3529例冠状动脉CTA受检者中,共检出冠状动脉变异42例（1．19％,42／3529）,MIP、VRT、CPR重建图像均明确显示其开口及走行;其中右冠状动脉起自主动脉左冠状窦者9例,左冠状动脉起自主动脉右冠状窦者2例,左回旋支异位开口于右冠窦1例,冠状动脉高位开口于升主动脉壁者6例．并行左主干3例（前降支、旋支分别开口于左冠窦）,左主干开口于肺动脉伴右冠状动脉瘤1例,左旋支-冠状静脉瘘者2例,副冠状动脉9例,右冠状动脉-左心室瘘合并右冠状动脉瘤l例。冠状动脉发育不良8例。结论冠状动脉CTA能准确显示各种类型冠状动脉变异,可作为无创性诊断冠状动脉变异的首选方法。     

冠状动脉变异的64层螺旋CT成像与诊断

目的:总结大样本病例64排螺旋CT冠状动脉成像中发现的冠状动脉变异类型及数量,为临床诊治提供依据,积累冠状动脉活体形态学资料,提高对冠状动脉变异的认识。方法:对694例受检者进行心脏冠脉成像检查,并对其图像进行回顾性分析。结果:694例受检者中,44例发现4种不同类型冠状动脉变异,占总数6.34%。其中副冠状动脉33例,RCA起源于左窦2例,LCX起源于右窦7例,左冠状动脉开口异常2例。结论:64排螺旋CT冠状动脉成像可以无创观察冠状动脉解剖及变异,为临床治疗提供依据。对冠状动脉细小分支的显示及对冠状动脉变异的认识有待提高。     

Left ventricular ejection fraction using 64-slice CT coronary angiography and new evaluation software: initial experience

The purpose of this study was to evaluate the feasibility and reliability of software-based quantification of left ventricular function using 64-slice CT coronary angiography. Data were collected from 26 subjects who underwent a 64-slice coronary CT angiography study. Two volumetric data sets at end diastole and end systole were reconstructed from each scan by means of retrospective electrocardiogram gating. Data sets were evaluated with a prototype of now commercially available software (Syngo Circulation I; Siemens Medical Solutions, Erlangen, Germany), which automatically segments the blood volume in the left ventricle after the user defines the mitral valve plane and any point within the ventricle. After segmentation of the blood pool in end systole and end diastole, the software automatically measures end systolic and end diastolic volume and calculates stroke volume and ejection fraction (EF). Two readers processed all CT data sets twice to assess for intra- and inter-observer variation. In addition, CT EF measurements were compared with those obtained by clinical echocardiography. Intra-observer variation for the calculated EF with CT were 13.6% and 15.6% for Readers 1 and 2, respectively. No significant difference in left ventricular functional parameters on CT existed between the readers (p > 0.05). A Bland-Altman plot revealed a slight mean difference between EF measurements on CT and echocardiography, with all differences falling within two standard deviations of the mean in the setting of wide limits of agreement. In conclusion, assessment of left ventricular EF from CT coronary data using the new analysis software is rapid and easy. The software is user-friendly and provides good reproducibility for EF measurements with CT.     

Imaging of myocardial infarction using a 64-slice MDCT scanner: Correlation between infarcted region and status of territory-dependent coronary artery

PURPOSE: This study was performed to evaluate the ability of 64-slice multidetector computed tomography (MDCT) to detect previous myocardial infarctions (MIs) in patients referred for the assessment of the coronary arteries. In patients with regional changes of left ventricular wall myocardial density, the territory-dependent coronary vessel status was examined. MATERIALS AND METHODS: We retrospectively assessed 202 consecutive patients referred for 64-slice MDCT of the coronary arteries. In all cases, detailed, clinical, serological and electrocardiograph (ECG) data were collected to identify patients with a previous diagnosis of MI. An initial qualitative evaluation of MDCT images was performed in all patients to identify areas of suspected myocardial necrosis, which were defined as regions of lower density within normally enhanced left ventricular myocardium. Thereafter, in all patients with suspected MIs, attenuation values and left ventricular wall thickness were also measured at the level of the normal myocardium and within the hypodense regions. Each MI was also assigned to the distribution territory of a coronary vessel, and morphological data were combined with MDCT angiographic findings. RESULTS: After clinical assessment, MI was found in 27 patients (six acute).; 64-slice MDCT was able to detect the presence of MI in 24/27 cases, showing sensitivity and specificity of 89% and 95%, respectively, and an overall diagnostic accuracy of 95%. Quantitative analysis showed a significant difference (p<0.01) between attenuation values of normal vs. infarcted myocardium (124.5+/-19 HU vs. 56.1+/-23 HU, respectively); wall thinning was exclusively observed in chronic MIs (p<0.01). In 23/24 detected cases, analysis of territory-dependent arteries showed findings compatible with presence of MI. CONCLUSIONS: The presence of MI is well depicted with retrospective 64-slice MDCT. The main advantage of 64-slice MDCT is that it allows to evaluate and relate the status of a vessel and its dependent myocardial region in a single exam.