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1.
In 190 1,Taylorreportedthefirstcaseofaspinalcordtumorassociatedwithpapilloedema ThetumorwasattheC3level ArseniandMaretsisreviewed 2 89casesofspinalcordtumor (1935- 196 5) ,andfoundonly 3casesassociatedwithpapilloedema 1 Matzkin 1992reviewed 53casesofspinaltumorassociated… 相似文献
2.
Endothelin (ET)wasoriginallyidentifiedin 1988asavasoconstrictorcompoundintheculturesupernatantofporcineaorticendothelialcells 1 ETs (ET 1,ET 2andET 3)are 2 1aminoacidpeptides 2 NumerouscellssynthesizeandreleaseETs ,includingmainlyETcells ,butalsohumanisolatedbronc… 相似文献
3.
Theobese(ob)gene,whichcausesseverehereditaryobesityandnoninsulindependentdiabetesmellitus(NIDDM)inmice,hasbeenclonedrecently1 Inmice,mutationsorabnormalexpressionofthisgenecauseprofoundobesity1 Theadministrationofrecombinantobprotein(leptin)cancorrecttheo… 相似文献
4.
A randomized controlled clinical trial on etimicin, a new aminoglycoside antibiotic, versus netilmicin in the treatment of bacterial infections 总被引:3,自引:0,他引:3
Etimicinsulfate (Antibiotic 89 0 7)isacategoryⅠdrugdevelopedbytheInstituteofMicrobiologyofJiangsuProvince ,China ItisanacetylderivativeofgentamicinC1a ThechemicalstructureisshowninFig 1Theresultsfromaninvitroantibacterialactivitystudyon 110 6strainsofclinicalpa… 相似文献
5.
Neutrophilsplayanimportantrolehostdefensesystemagainstinfection Theneutrophilsgranulesfallintoperoxidase positivegranulesdefinedbytheircontentsofmyeloperoxidase (MPO)andperoxidase positivegranuleswhichmaybefurthersubdividedintospecificgranulesandgelatin… 相似文献
6.
Chemoprotection of transfer of multidrug resistance gene into human hematopoietic progenitor cell 总被引:3,自引:0,他引:3
Mostofgynecologicmalignancesaresensitivetochemotherapy Bonemarrowsuppressionisthemaindose relatedtoxicityofmanychemotherapeuticdrugs Standardtreatmentforthiscomplicationinvolvestheuseoftransfusionalsupport,hematopoieticcytokines ,pharmacologicalrescue ,a… 相似文献
7.
Management of cerebral ischemia due to Takayasu''''s arteritis 总被引:2,自引:0,他引:2
Aortoarteritis ,alsocalledTakayasu’sarteritis ,isachronicidiopathicinflammatorydiseasethataffectslargeandmediumsizearteries Clinicalfeaturesreflectlimbororganischemiaresultingfromstenosistoobliterationofinvolvedarteries Thisdisease ,describedbyTakayasuin… 相似文献
8.
Inhalationofirritantgasesisaneasyandreliablewaytoproduceananimalmodelofchronicbronchitis 1 ThefirstsuchmodelwasestabishedbyReid2 in 196 3andhasbeenwidelyusedsincethattime 3 Chronicobstructivepulmonarydiseaseisdefinedasaconditioninwhichthereispermanentairf… 相似文献
9.
Withinthepasttenyears,therehasbeenincreasinginterestinthedetectionofspecificDNAsequencesusingmethodswhichdonotrequiretheuseofradioisotopes ,enzymesorfluorophores Biosensorsystemsbasedonnucleicacidnotonlyeliminatetheneedforsuchlabelsbutalsoofferthepoten… 相似文献
10.
Increased expression of intercellular adhesion molecule-1 i n mouse focal cerebral ischemia model 总被引:13,自引:2,他引:11
葛海良 《中华医学杂志(英文版)》2000,113(1):75-79
Intercellularadhesionmolecule 1(ICAM 1) ,asingle chain 76 - 110kDaglycoprotein ,isamemberoftheimmunoglobulinsupergenefamily ICAM 1hasbeenidentifiedasaligandforleukocyteadhesionmoleculedesignatedasalymphocytefunction associatedantigen(LFA 1) TheinteractionofICAM 1wi… 相似文献
11.
Proadrenomedullin (Pro ADM)isaprecursorencodedbytheadrenomedullingene Therearetypicallythreepairedbasicaminoacids ,whichrepresentsitesforproteolyticprocessingsignalinPro ADM ProteolyticcleavagesofPro ADMatthreesitesreleasefourpeptides :Pro ADM2 2 4 1(prodepino… 相似文献
12.
Lineargrowthisasensitiveindicatorofthegeneralhealthofchildrenandheightmeasurementisthereforeoneofthemostimportantclinicalfindinginpaediatrichealthsurveillance Infact,shortstature (SS)isacommonproblemforchildrenandadolescentsworldwideandisfrequentlyapre… 相似文献
13.
Brain MRI of hippocampal volumetry in patients with refractory temporal lobe epilepsy 总被引:1,自引:1,他引:0
Ka Kui Philip Ng Kwok Wing Tang Yuk Ling James Cheung Patrick Chung Ki Li 《中华医学杂志(英文版)》2000,113(3):254-256
BrainMRIhasbroughtonrevolutionarychangesinthemanagementofpatientswithepilepsy AlargenumberofpatientswhowerepreviouslydiagnosedtohavecryptogenicepilepsyarenowreclassifiedassymptomaticepilepsysincecausescanbeidentifiedafterbrainMRI Thisnotonlyimprovesth… 相似文献
14.
Nitricoxide (NO)asanubiquitousmoleculeplaysanimportantroleintheneuraldevelopmentandintheprocessofapoptosis 1 Recentreportsindicatedthatheatshockproteins (hsps)couldfacilitatedifferentiationinthemalignanttumorcells2 andthattheneuronspecificenolase(NSE)coul… 相似文献
15.
Deep cerebral venous thrombosis in adults 总被引:23,自引:0,他引:23
Deepcerebralvenousthrombosis (DCVT)isarareformofcerebralvasculardisease Itmostoftenoccursinchildrenandinfants DCVTdiagnosisandprognosismayoftenbedifficult OurrecentexperiencehasledustorecognizethatDCVTpresentswithanatypicalsyndromeandtimecourse ,characte… 相似文献
16.
AP-1 mediated signal transduction in thrombin-induced regulation of PAL-1 expression in human mesangial cells 总被引:3,自引:0,他引:3
Thrombin ,aserineprotease ,mediatescoagulation ,andstimulatescellproliferation ,adhesion ,migration ,andangiogenesis Italsoinducestheexpressionofcertaincytokinesandgrowthfactors 1,2 Plasminogenactivatorinhibitor 1(PAI 1)isrecognizedasthemajorinhibitoroftheplasm… 相似文献
17.
EndotoxicshockisasystemicdisordercharacterizedbyexcessiveactivationofvariousorgansLungisknowntobeaprimetargetorganofendotoxinlipopolysaccharide(LPS)1Recently,nitricoxide(NO)wasfoundtobeinvolvedinexperimentalendotoxemia,2 andhasbeenregardedasthemajorfacto… 相似文献
18.
p53 mutation, EGFR gene amplification and loss of heterozygosity on chromosome 10, 17 p in human gliomas 总被引:3,自引:1,他引:2
ethods p53mutationswerescannedin 50gliomaswithvariousmalignantgradesusingthepolymerasechainreactionsinglestrandconformationpolymorphism(PCR SSCP)assay ,andwereconfirmedbydirectsequencing LOHforchromosome 10 ,17pandamplificationoftheEGFRgenewerealsoassessedusi… 相似文献
19.
Testicular sperm extraction and intracytoplasmic sperm injection in non-obstructive azoospermia 总被引:3,自引:0,他引:3
Ng Hung Yu Ernest Lau Yee Lan Yeung Shu Biu So Wai Ki Tam Po Chor Ho Pak Chung 《中华医学杂志(英文版)》2000,113(3):246-250
About 10 % - 15%ofcoupleswillexperienceinfertilityatsometimeduringreproductiveyearsandmalefactorsmaybeinvolvedin 30 % - 50 %ofthesecases 1,2 Azoospermiacausedbyprimarytesticularfailure ,i e non obstructiveazoospermia (NOA ) ,isusuallyirreversibleanditwaspreviouslynotp… 相似文献
20.
BoththeUSCentersforDiseaseControl (CDC) 1 andtheWorldHealthOrganization (WHO )recommendthatisoniazidpreventivetherapy (IPT)againsttuberculosis (TB)beroutinelygiventohumanimmunodeficiencyvirus (HIV)infectedpersonswithpositiveskinteststothepurifiedproteinderiva… 相似文献