Does BMI influence hospital stay and morbidity after fast-track hip and knee arthroplasty?

Background and purpose — Body mass index (BMI) outside the normal range possibly affects the perioperative morbidity and mortality following total hip arthroplasty (THA) and total knee arthroplasty (TKA) in traditional care programs. We determined perioperative morbidity and mortality in such patients who were operated with the fast-track methodology and compared the levels with those in patients with normal BMI.

Patients and methods — This was a prospective observational study involving 13,730 procedures (7,194 THA and 6,536 TKA operations) performed in a standardized fast-track setting. Complete 90-day follow-up was achieved using national registries and review of medical records. Patients were grouped according to BMI as being underweight, of normal weight, overweight, obese, very obese, and morbidly obese.

Results — Median length of stay (LOS) was 2 (IQR: 2–3) days in all BMI groups.

30-day re-admission rates were around 6% for both THA (6.1%) and TKA (5.9%), without any statistically significant differences between BMI groups in univariate analysis (p > 0.4), but there was a trend of a protective effect of overweight for both THA (p = 0.1) and TKA (p = 0.06).

90-day re-admission rates increased to 8.6% for THA and 8.3% for TKA, which was similar among BMI groups, but there was a trend of lower rates in overweight and obese TKA patients (p = 0.08 and p = 0.06, respectively). When we adjusted for preoperative comorbidity, high BMI in THA patients (very obese and morbidly obese patients only) was associated with a LOS of >4 days (p = 0.001), but not with re-admission. No such relationship existed for TKA.

Interpretation — A fast-track setting resulted in similar length of hospital stay and re-admission rates regardless of BMI, except for very obese and morbidly obese THA patients.     

Are leg length and hip offset comparable after hip resurfacing and cementless total hip arthroplasty?

INTRODUCTION

The purpose of this study was to determine if hip resurfacing arthroplasty (HRA) and cementless total hip arthroplasty (THA) were comparable in correcting leg length and hip offset in patients with primary osteoarthritis.

METHODS

A retrospective analysis was performed of 80 patients who underwent either HRA or cementless THA for primary osteoarthritis (40 in each group) between 2006 and 2008. Standardised anteroposterior radiographs taken pre-operatively and at one year following surgery were used to calculate the total offset and leg length in both hips.

RESULTS

At one year following surgery, no leg length discrepancy was identified in either group. A difference of 0.39cm (p=0.046) remained between the mean total offset of the operated hip and the contralateral non-operated hip in the HRA group. No difference in offset was observed between the two hips after surgery in the THA group (p=0.875).

CONCLUSIONS

Leg length is restored by HRA and THA. A difference remains in offset after HRA although we attribute this to intentional medialisation of the acetabular cup.     

Cemented total hip arthroplasty: still relevant in the new millennium?

Total hip arthroplasty can be performed successfully using cement or cementless technology. Cemented femoral stems can achieve enduring long-term suvivorship as long as meticulous surgical technique is utilized and patient selection is appropriate. Cemented acetabular components should only be utilized in patients with less than 10 years of remaining life expectancy. Critical risk factors for cemented total hip arthroplasty include atrophic osteoarthrtis on the acetabular side and unfavorable femoral geometry for the femoral stem such as "the stove-pipe" canal. Rapid polyethylene wear and osteolysis are rarely seen in contemporary cemented total hip arthroplasty performed with a smooth, tapered, collarless femoral stem with a highly polished head and a well-designed acetabular component.     

Barbed sutures in total hip and knee arthroplasty: what is the evidence? A meta-analysis

Introduction

Newer methods of wound closure such as bidirectional barbed sutures hold the potential to reduce closure time and thus overall operating room costs during total joint arthroplasty (TJA), including total hip arthroplasty (THA) and total knee arthroplasty (TKA). However, it is unclear whether these sutures have similar clinical outcomes or whether they place the patient at risk of developing wound complications that may outweigh the time-saving benefits of these sutures.

Methods

A systematic review of the literature was performed to identify all level I trials that reported the use of barbed suture during TJA. We analyzed the efficacy, safety, major and minor complications, and overall cost related to barbed sutures.

Results

Four studies met our criteria, and included 588 patients who were randomized either to barbed suture closure (n?=?290 TJAs, 268 TKAs, and 22 THAs) or to a matched conventional suture cohort (n?=?298 TJAs, 279 TKAs, and 19 THA). In terms of time savings with wound closure, the barbed suture was 6.3 minutes faster than the conventional cohort (p?<?0.05). The odds for developing a minor complication were nearly identical (odds ratio [OR] 1.04, p?=?0.95) and for major complication was not significantly different (OR 2.94, p?=?0.27). The overall mean savings including both THA and TKA was USD 298 per case.

Conclusions

In randomized controlled trials, barbed sutures are consistently associated with shorter wound closure time, which also corresponds to cost savings, even when the higher cost of these sutures is taken into account. There was no significant difference in the odds of experiencing either minor or major complications between patients in whom barbed sutures versus standard sutures were used for wound closure. Current evidence supports continued use of these sutures.Level of Evidence: Level I

     

Is decreasing mortality in total hip and knee arthroplasty patients dependent on patients’ comorbidity?

Background and purpose — Mortality after primary total hip and knee arthroplasty (THA and TKA) has declined, and the proportion of THA and TKA patients with comorbid conditions has increased. We therefore wanted to examine changes in comorbidity burden over time and the impact of comorbid on mortality following primary total hip and knee arthroplasty in patients with osteoarthritis.

Patients and methods — We used the Danish arthroplasty registers to identify THA and TKA patients from 1996 through 2013. From administrative databases, we collected data on pre-surgery hospital history for all patients, which were used to calculate the Charlson comorbidity index (CCI). Patients were divided into 4 groups: CCI-none, CCI-low, CCI-moderate, and CCI-high. We calculated the relative risk (RR) of mortality within 90 days after surgery with a 95% confidence interval (CI), with stratification according to CCI group and year of surgery.

Results — 99,962 THAs and 63,718 TKAs were included. The proportion of THAs with comorbidity increased by 3–4% in CCI-low, CCI-moderate, and CCI-high patients, from 1996–1999 to 2010–2013. The overall 90-day mortality risk declined for both procedures. Compared to CCI-none, THA patients with low, moderate, and high comorbidity burdens had an RR of 90-day mortality of 1.9 (95% CI: 1.6–2.4), 1.9 (CI: 1.5–2.5), and 3.3 (CI: 2.6–4.2), respectively. Similar increases in proportions and RRs were observed in TKAs.

Interpretation — Despite the fact that the proportion of THA and TKA patients with comorbidities has increased over the past 18 years, the overall mortality has declined. The mortality risk depended on the comorbidity burden and did not decline during the study period for THA and TKA patients with a moderate or high comorbidity burden at the time of surgery.     

Are surgeons equally satisfied after total knee arthroplasty?

Introduction We performed a clinical follow-up study to investigate whether three orthopaedic surgeons were equally satisfied after total knee arthroplasty (TKA).Patients and methods Thirty-six patients (39 TKAs, mean follow-up 12 months) were reviewed, using the Knee Society Clinical Rating System (KSCRS). For the assessment of satisfaction a visual analogue scale (VAS) was used.Results We did not find a significant difference in satisfaction between the surgeons. However, there was a significant difference in the knee score and function score of the KSCRS as evaluated by the orthopaedic surgeons (p=0.006 and p=0.04, respectively). The correlation between the knee score and the surgeons satisfaction was high, which indicates that pain, range of motion and deformity are important success criteria for surgeons.Conclusions In this study, surgeons scored differently in the KSCRS but were equally satisfied after TKA.     

Continuous femoral nerve block after total knee arthroplasty?

Background: A continuous femoral nerve block is frequently used as an adjunct therapy after total knee arthroplasty (TKA). However, there is still debate on its benefits.
Methods: In this prospective, randomized study, patients received a basic analgesic regimen of paracetamol and dicloflenac for the first 48 h postoperatively. In addition, the study group received a continuous femoral nerve block. A morphine patient-controlled analgesia pump was also available as a rescue analgesic to all the patients. Patients' numeric rating scores for pain, the amount of morphine consumed and its side effects during the first 48 h were recorded. Knee flexion angles achieved during the first week were registered. Three months postoperatively, patients completed Western Ontario and McMaster Universities Osteoarthritis Index and Knee Society Score.
Results: The study group ( n =27) had less pain ( P =0.0016) during the first 48 h, was more satisfied with the analgesia ( P <0.001) and used less morphine ( P =0.007) compared with the control group ( n =26). Fewer patients were nauseated, vomited or were drowsy in the study group ( P =0.001). Also, the study group achieved better knee flexion in the first 6 days after surgery ( P =0.001), with more patients reaching 90° flexion than the control group. However, after 3 months, there were no significant functional differences between the groups.
Conclusion: A continuous femoral nerve block leads to better analgesia, less morphine consumption and less morphine-related side effects after TKA. Early functional recovery is improved, resulting in more patients reaching 90° knee flexion after 6 days. However, after 3 months, no significant functional benefits were found.     

1–year follow–up of 920 hip and knee arthroplasty patients after implementing fast–track: Good outcomes in a Norwegian university hospital

BackgroundFast–track has become a well–known concept resulting in improved patient satisfaction and postoperative results. Concerns have been raised about whether increased efficiency could compromise safety, and whether early hospital discharge might result in an increased number of complications. We present 1–year follow–up results after implementing fast–track in a Norwegian university hospital.MethodsThis was a register–based study of 1,069 consecutive fast–track hip and knee arthroplasty patients who were operated on between September 2010 and December 2012. Patients were followed up until 1 year after surgery.Results987 primary and 82 revision hip or knee arthroplasty patients were included. 869 primary and 51 revision hip or knee patients attended 1–year follow–up. Mean patient satisfaction was 9.3 out of a maximum of 10. Mean length of stay was 3.1 days for primary patients. It was 4.2 days in the revision hip patients and 3.9 in the revision knee patients. Revision rates until 1–year follow–up were 2.9% and 3.3% for primary hip and knee patients, and 3.7% and 7.1% for revision hip and knee patients. Function scores and patient–reported outcome scores were improved in all groups.InterpretationWe found reduced length of stay, a high level of patient satisfaction, and low revision rates, together with improved health–related quality of life and functionality, when we introduced fast–track into an orthopedic department in a Norwegian university hospital.The health service in Norway has been reorganized in the last decade. The number of available beds and the length of stay (LOS) in somatic hospitals have been reduced. Patients are increasingly being treated as outpatients rather than being admitted to hospital (SSB 2011). Changes in treatment modalities have contributed to this reorganization. Within elective surgery, the “fast–track” principles are increasingly being adopted, although there is still potential for improvement regarding both treatment and clinical results (Rostlund and Kehlet 2007, Kehlet and Soballe 2010). Fast–track originated in Denmark—in gastrointestinal surgery—and has been further developed and documented in joint replacement surgery in hospitals in Denmark over the last decade (Rasmussen et al. 2001, Husted et al. 2010a,d, 2012, Leonhardt et al. 2010). The fast–track concept is an evidence–based multimodality treatment that reduces convalescence time and improves clinical results, including reduction in morbidity and mortality (Kehlet and Wilmore 2008, Schneider et al. 2009). The particularly important elements are: anesthesia, fluid therapy, pain therapy, and early postoperative mobilization (Husted and Holm 2006, Husted et al. 2010a, 2011a, 2012, Khan et al. 2014) as well as preoperative information and supervision (Kehlet 1997, Andersen et al. 2007, 2009, Holm et al. 2010).It has been said that fast–track may result in increased complication rates and re–admissions (Mauerhan et al. 2003). However, several studies have found that reduced length of stay does not compromise patient safety (Pilot et al. 2006, Mahomed et al. 2008, Schneider et al. 2009) or increase complication rates compared to conventional treatment methods (Husted et al. 2010b). Also, it has been shown that fast–track surgery with early mobilization and short deep–vein thrombosis prophylaxis results in low rates of deep–vein thrombosis and pulmonary embolism (Husted et al. 2010c, Jorgensen et al. 2013).A reorganization in the orthopedic department at Trondheim University Hospital in 2010 led to an increased number of knee and hip arthroplasty patients, from 7 to 17 a week (Egeberg et al. 2010). Based on the successful implementation of fast–track in several hospitals in Denmark (Husted et al. 2008, Kehlet and Wilmore 2008), this model was adopted in our department. To be able to continually monitor treatment quality and process data, we established an internal quality register (Bjorgen et al. 2012). We now present the 1–year follow–up results after implementation of this fast–track procedure.     

Is knee osteotomy still indicated in knee osteoarthritis?

This study was undertaken to investigate whether high tibial osteotomy (HTO) still had a role in the treatment of osteoarthritis of the knee joint. The author has performed photoelasticity studies which confirmed abnormal stress distribution over the joint, as soon as its mechanical axis was deviated and the joint line had an obliquity over 10 degrees. High tibial osteotomy to correct varus or valgus deformity restores a symmetrical stress distribution and represents the only etiological treatment of secondary osteoarthritis of the knee. Two hundred and fifty HTO's were performed between 1971 and 1985 for osteoarthritis of the knee. The short-term result was good or very good in 75%, fair in 20% and poor in 5%. Fair and poor results were related to insufficient correction, to infection or mostly to incorrect indications. In 152 cases with a good or very good short term result, a further evaluation was made between 8 years and 15 years after operation. It was noted that osteoarthritis had been arrested in 105 cases (69%) whereas it had deteriorated in 47 cases. The main factors associated with further deterioration were insufficient correction and persistence of joint line obliquity. Provided on optimal correction is achieved (3 degrees to 6 degrees hypercorrection in valgus osteotomy, 0 degree in varus osteotomy) and provided a horizontal joint line is restored, HTO performed in good indications (Ahlback grade I or II) may provide good results for at least 10 to 15 years.     

Is etoricoxib effective in preventing heterotopic ossification after primary total hip arthroplasty?

Purpose

Heterotopic ossification is a common complication after total hip arthroplasty. Non-steroidal anti-inflammatory drugs (NSAIDs) are known to prevent heterotopic ossifications effectively, however gastrointestinal complaints are reported frequently. In this study, we investigated whether etoricoxib, a selective cyclo-oxygenase-2 (COX-2) inhibitor that produces fewer gastrointestinal side effects, is an effective alternative for the prevention of heterotopic ossification.

Methods

We investigated the effectiveness of oral etoricoxib 90 mg for seven days in a prospective two-stage study design for phase-2 clinical trials in a small sample of patients (n = 42). A cemented primary total hip arthroplasty was implanted for osteoarthritis. Six months after surgery, heterotopic ossification was determined on anteroposterior pelvic radiographs using the Brooker classification.

Results

No heterotopic ossification was found in 62 % of the patients that took etoricoxib; 31 % of the patients had Brooker grade 1 and 7 % Brooker grade 2 ossification.

Conclusions

Etoricoxib seems effective in preventing heterotopic ossification after total hip arthroplasty. This finding further supports the use of COX-2 inhibitors for the prevention of heterotopic ossification following total hip arthroplasty.     

Perioperative urinary catheterisation in conjunction with epidural anaesthesia for hip and knee arthroplasty. Is it safe?

The place of indwelling urinary catheterisation following epidural anaesthesia to prevent acute retention of urine after hip and knee arthroplasty is controversial. Even with the use of aseptic techniques and closed sterile drainage, bacteriuria has been reported in 10-27% of catheterised patients. A prospective trial was carried out in 68 consecutive patients undergoing knee or hip joint arthroplasty with epidural anaesthesia to investigate the perioperative complications of short term urinary catheterisation. Following establishment of combined epidural and general anaesthesia, all patients underwent urinary catheterisation under aseptic technique by a member of the surgical team. Prophylactic antibiotics were given prior to insertion and continued for 24-48h postoperatively to minimise the risk of prosthetic infection. The mean indwelling urinary catheter (IDC) period was 3.6 days (range 2-14). There were three (4.4%) urinary tract infections (UTIs) all of which resolved with appropriate antibiotics. Two were detected upon removal of the urinary catheter and one was detected on the seventh postoperative day when symptoms were detected. No patient required recatheterisation. There was no other infective morbidity or wound infection. Our findings suggest the use of IDC for short periods combined with prophylactic antibiotics is safe in the perioperative phase of joint arthroplasty.     

Causes of a painful total knee arthroplasty. Are patients still receiving total knee arthroplasty for extrinsic pathologies?

Purpose

Whilst patients undergoing total knee replacements generally have good relief of their symptoms, up to 20% complain of persisting pain. Revision rates have therefore been rising, particularly so for unexplained pain. We reviewed the causes of painful total knee replacements including extrinsic causes.

Methods

Forty-five consecutive patients referred to our department with painful total knee replacement were reviewed with our standard protocol, including history and examination, inflammatory markers and radiological studies including radiographs of the hip and knee and computed tomography scan of the knee joint.

Results

Of the 45 patients, 15 patients had degenerative hip and lumbar spine disease which resolved after injections of the relevant joints. Nine patients had unexplained pain.

Conclusions

Patients may still be undergoing knee arthroplasty for degenerative lumbar spine and hip osteoarthritis. We suggest heightened awareness at pre- and post-operative assessment and thorough history and examination with the use of diagnostic injections to identify the cause of pain if there is doubt.     

New materials for hip and knee joint replacement: What's hip and what's in kneed?

Over the last three decades there have been significant advancements in the knee and hip replacement technology that has been driven by an issue in the past concerning adverse local tissue reactions, aseptic and septic loosening. The implants and the materials we utilize have improved over the last two decades and in knee and hip replacement there has been a decrease in the failures attributed to wear and osteolysis. Despite these advancements there are still issues with patient satisfaction and early revisions due to septic and aseptic loosening in knee replacement patients. This article reviews the state of current implant material technology in hip and knee replacement surgery, discusses some of the unmet needs we have in biomaterials, and reviews some of the current biomaterials and technology that may be able to solve the most common issues in the knee and hip replacement surgery.     

Does unilateral total hip arthroplasty improve pain and function in the non-operative hip joint?

European Journal of Orthopaedic Surgery & Traumatology - Some reports suggested that the status of the opposite-side hip affects clinical outcomes of unilateral total hip arthroplasty (THA) for...