头孢克洛治疗尿路感染30例临床分析

尿路感染是临床上常见疾病,治疗尿路感染的药物有多种,寻找有效治疗尿路感染的药物深为人们所关注。头孢克洛为口服头孢菌素类广谱抗生素,具有较强的灭菌作用,笔者观察３０例应用头孢克洛治疗尿路感染的患者都获得了较好的疗效。１资料和方法１． １对象： （１）治疗对象为 ３０例患有尿路感染的内科门诊病人,其中男性６例,女性２４例,年龄２５～６５岁,平均４９．５岁。（２）按第二届全国肾脏病学术会议制定的诊断标准,确认３０例中下尿路感染１３例,急性肾盂肾炎８例,慢性肾盂肾炎９例。３０例患者治疗前后均做消毒中段尿细…     

头孢克洛分散片治疗下尿路感染50例疗效观察

目的：评价头孢克洛分散片治疗下尿路感染的临床疗效及不良反应。方法：采用开放研究方法观察用药５～８天的疗效及不良反应。结果：５０例中痊愈４４例,显效３例,总有效率为９４％,细菌清除率为８８％,未见明显不良反应。结论：头孢克洛分散片治疗下尿路感染疗效好且应用方便。     

乳酸左氧氟沙星与头孢呋辛3日疗法随机对照治疗疗尿路感染 …

以乳酸左氧氟沙星片为试验药与头孢呋辛随机对照,用３日疗法治疗急性尿路感染７６例。乳酸左氧氟沙星２００ｍｇ,每日２次口服;头孢呋辛２５０ｍｇ,每日２次口服,疗效均为３d。结果试验药组与对照药组总有效率分别为９４．７％和８９．５％。细菌清除率分７．９％和１３％。结果证明乳酸左氧氟沙星３日疗法治疗急性尿路感染是安全、有效的药物之一。     

乳酸左氧氟沙星治疗尿路感染的临床研究

为研究乳酸左氧氟沙星治疗尿路感染的临床疗效,对３１例尿路感染患者,根据病情严重程度分别给予乳酸左氧氟沙星每次０．１～０．２g,静脉注射或口服,每日２次,疗程７～ １０ｄ。观察患者症状、体征及实验室检查。结果３１例患者使用乳酸左氧氟沙星治疗后总有效率为９１．３％,其中５例肾功能不全氮质血症患者用药后未见肾功能恶化。提示乳酸左氧氟沙星是治疗尿路感染安全有效的药物,值得推广。     

头孢克洛胶囊鉴别方法的改进

头孢克洛胶囊鉴别方法的改进姚连初（浙江省德清市第一人民医院德清３１３２００）王丽华（中国药科大学）头孢克洛是新开发的口服头孢类抗生素。近年来我国已有头孢克洛制剂，其鉴别方法是参照中国药典１９９５年版二部１７８页头孢氨苄的有关物质检查项下，用薄层色谱法...     

北京地区市售头孢克洛胶囊质量评价

目的考察北京地区市售头孢克洛胶囊的质量。方法采用现行法定标准方法与非标的文献方法对11家企业的45批样品进行检验。结果各企业产品均符合现行法定标准规定。结论本产品工艺较为成熟,产品质量较好,企业之间产品质量差异不大。     

HPLC法测定头孢克洛原料、头孢克洛片的含量

采用HPLC法定量测定头孢克洛原料、头孢克洛片的含量。以NuclesoilC18柱为分析柱 ,0 .1mol/L磷酸盐缓冲液 (pH =4 .5) -乙腈 (94 0∶60 )为流动相 ,检测波长为 2 54nm。实验表明 ,该法线性良好 ,平均回收率 99.4 % ,RSD =0 .4 3% (n =6)     

头孢克洛缓释胶囊治疗呼吸道感染189例观察

目的 观察头孢克洛缓释胶囊（曼宁）治疗呼吸道感染的临床疗效和安全性。方法 口服头孢克洛缓释胶囊0．5g／次，2次／d，疗程7～10d。结果 总有效率86．2％，细菌清除率83．8％，不良反应发生率1．6％。结论 头孢克洛缓释胶囊治疗下呼吸道感染安全有效。     

头孢克洛胶囊溶出度测定方法研究

本文对头孢克洛胶囊的溶出度进行了检测，即采用传篮法，以胃液０．１ｍｏｌ／Ｌ盐酸液为溶剂，转速１００ｒｐｍ，时间为２小时，测定波２６７±１）ｎｍ；以肠液ＰＨ６．８磷酸盐缓冲液为溶剂，转速１００ｒｐｍ，时间为４５分钟，测定波为（２６４±１）ｎｍ；依法测定头孢克洛胶囊６批，在胃液，肠液中溶出量均大于８０％，结果满意。     

头孢克洛缓释胶囊治疗手足软组织感染疗效观察

我院于2002年10月至2004年8月期间收治了20例手足软组织感染患者，给予口服头孢克洛缓释胶囊治疗取得了满意的疗效。现总结如下。     

儿童泌尿系感染36例临床分析

目的 探讨儿童泌尿系感染(UTI)的临床特点,为临床诊治提供参考.方法 对36例泌尿系感染患者的临床表现、辅助榆查结果、治疗等临床资料进行回顾分析.结果 本组中有发热、呕吐、烦躁、哭闹、易激惹等非特异表现者13例(36.11%);有明显尿路刺激症状15例(41.67%);发热、腹痛者3N(8.33%);单纯腹痛者2例(...     

头孢克洛治疗上呼吸道感染的临床观察

目的：探讨头孢克洛治疗上呼吸道感染的临床疗效。方法选取本院2O11年1月-2O13年8月收治的76例上呼吸道感染患者,将患者随机分为观察组和对照组,每组38例。对照组患者给予口服头孢氨苄治疗,观察组患者给予口服头孢克洛治疗,观察两组患者的临床症状、体征消失时间及临床疗效。结果观察组患者治疗后的临床症状及体征消失时间均少于对照组,差异有统计学意义（P 〈0. O5）。观察组患者治疗总有效率为92.1%,对照组为89.5%,两组比较差异无统计学意义（P 〉0. O5）。结论头孢克洛治疗上呼吸道感染临床疗效好,能够促进患者临床症状及体征的消失,值得临床进一步推广使用。     

365例尿路感染住院患儿临床及感染菌耐药性分析

目的:探讨儿童尿路感染的临床特点,指导临床治疗.方法:回顾性分析365例儿童尿路感染住院患儿的临床资料.结果:(1)尿路感染住院患儿中,性别分布随年龄不同而不同,男孩以3岁以下多见,女孩以3岁以上多见.(2)无症状菌尿者占59.18%,与年龄、性别无关.(3)复杂尿路感染占76.16%,合并的复杂因素主要为肾病综合征(...     

儿童泌尿系感染36例临床分析

Objective To investigate the clinical features of 36 children with urinary tract infection(UTI).Methods Clinical situation,auxiliary examination,and remedy of the 36 children with UTl was retrospectively analyzed.Results 13 of the 36 children with UTI presented with non-specific clinleal manifestation,sueh as feVer,vomiting,restlessness,erying,and irritability;15 with the clear signs of UTI,including increased frequency of urination,dysuria,and urgency;3 with fever and stomachache:2 only with stomachache;3 with strong-smelling urine.Centrifugate urinary sediment of all patients teated under microscope showed WBC＞5/Hp,urine culture and colony count were performed in 28 Phildren wiIh UTI,with 19 positive and 9 negative.Culture's positive rate ofthe patients who had not used antibotics before the test was higher than those who had used.Urinary tract abnormalities detected by iconography were found in 9 children.Ctmdusion Signs and symptoms of children with UTI were non-specificity,early diagnosis of UTI were based on the urine tests.After UTI was diagnosed,potential etiological factors of UTI musl be researched,UTI closely correlated to urinary tract abnormalities.Strictly follow-up of the children with UTI call help us find the potential abnormalities,prevent and cure the relapse of UTI,so as to prevent the kidney from further damage.     

儿童泌尿系感染36例临床分析

Objective To investigate the clinical features of 36 children with urinary tract infection(UTI).Methods Clinical situation,auxiliary examination,and remedy of the 36 children with UTl was retrospectively analyzed.Results 13 of the 36 children with UTI presented with non-specific clinleal manifestation,sueh as feVer,vomiting,restlessness,erying,and irritability;15 with the clear signs of UTI,including increased frequency of urination,dysuria,and urgency;3 with fever and stomachache:2 only with stomachache;3 with strong-smelling urine.Centrifugate urinary sediment of all patients teated under microscope showed WBC＞5/Hp,urine culture and colony count were performed in 28 Phildren wiIh UTI,with 19 positive and 9 negative.Culture's positive rate ofthe patients who had not used antibotics before the test was higher than those who had used.Urinary tract abnormalities detected by iconography were found in 9 children.Ctmdusion Signs and symptoms of children with UTI were non-specificity,early diagnosis of UTI were based on the urine tests.After UTI was diagnosed,potential etiological factors of UTI musl be researched,UTI closely correlated to urinary tract abnormalities.Strictly follow-up of the children with UTI call help us find the potential abnormalities,prevent and cure the relapse of UTI,so as to prevent the kidney from further damage.     

儿童泌尿系感染36例临床分析

Objective To investigate the clinical features of 36 children with urinary tract infection(UTI).Methods Clinical situation,auxiliary examination,and remedy of the 36 children with UTl was retrospectively analyzed.Results 13 of the 36 children with UTI presented with non-specific clinleal manifestation,sueh as feVer,vomiting,restlessness,erying,and irritability;15 with the clear signs of UTI,including increased frequency of urination,dysuria,and urgency;3 with fever and stomachache:2 only with stomachache;3 with strong-smelling urine.Centrifugate urinary sediment of all patients teated under microscope showed WBC＞5/Hp,urine culture and colony count were performed in 28 Phildren wiIh UTI,with 19 positive and 9 negative.Culture's positive rate ofthe patients who had not used antibotics before the test was higher than those who had used.Urinary tract abnormalities detected by iconography were found in 9 children.Ctmdusion Signs and symptoms of children with UTI were non-specificity,early diagnosis of UTI were based on the urine tests.After UTI was diagnosed,potential etiological factors of UTI musl be researched,UTI closely correlated to urinary tract abnormalities.Strictly follow-up of the children with UTI call help us find the potential abnormalities,prevent and cure the relapse of UTI,so as to prevent the kidney from further damage.     

甲磺酸左氧氟沙星治疗37例泌尿系感染观察

目的：研究甲磺酸左氧氟沙星治疗细菌性尿路感染的临床疗效和安全性。方法：采用随机对照试验方法，将72例细菌性尿路感染病人分为治疗组37例和对照组35例，分别给予甲磺酸左氧氟沙星和乳酸环丙沙星治疗。结果：两组临床总有效率分别为86．5％和82．8％，细菌清除率分别为86．5％和80．0％，不良反应发生率分别为5．4％和8．6％，经统计学处理，差异均无显著意义（P〉0．05）。结论：甲磺酸左氧氟沙星治疗细菌性尿路感染安全、有效。     

左氧氟沙星治疗男性泌尿生殖道感染的评价

目的：评价左氧氟沙星对男性泌尿生殖道感染的治疗作用及安全性。方法：随机对照试验。左氧氟沙星组（治疗组）和氧氟沙星组（对照组）各42例。结果：两组总有效率分别是95．24％,73．81％;细菌清除率分别为89．47％和71．05％;不良反应发生率分别为2．40％和7．14％。经统计学处理两组疗效有统计学差异（P〈0．01）。结论：左氧氟沙星治疗男性泌尿生殖道感染安全有效,不良反应少。     

糖尿病合并尿路感染120临床治疗分析

目的探索糖尿病合并尿路感染患者的有效治疗方法。方法回归性分析120例糖尿病合并尿路感染患者的临床资料,比较采用二甲双胍联合比格列酮控制血糖及抗感染治疗其他方法控制血糖及抗感染治疗对糖尿病尿路感染的治疗效果。结果 120例患者中43例采用二甲双胍联合比格列酮及抗感染治疗,治愈40例,好转2例,无效1例,治愈率93%,好转率5%,有效率98%。77例采用其他方法控制血糖及抗感染治疗,治愈54,好转19例,无效4例,治愈率70%,好转率25%,有效率95%。结论采用二甲双胍联合比格列酮及抗感染治疗,更有助于糖尿病尿路感染的治疗。     

血必净注射液联合左氧氟沙星治疗泌尿系统感染的临床观察

目的：观察血必净注射液联合左氧氟沙星治疗泌尿系统感染的临床疗效及安全性。方法：选择78例泌尿系统感染患者,按随机数字表法分为对照组（38例）和治疗组（40例）。对照组患者给予左氧氟沙星氯化钠注射液300mg静脉滴注,bid;治疗组患者在对照组患者治疗的基础上给予血必净注射液50ml加入0．9％氯化钠注射液100ml中静脉滴注,30-40min内滴完,bid。两组患者均治疗7d。观察两组患者治疗前、后临床症状及体征的变化,24h尿常规,肝、肾功能,血常规及不良反应发生情况。结果：治疗后,治疗组患者总有效率（82．5％）显著高于对照组（63．2％）,两组比较差异有统计学意义（P〈0．05）;两组患者治疗后尿常规各项指标较治疗前均显著改善,差异有统计学意义（P〈0．05）,但组间比较差异无统计学意义（P〉0．05）;两组患者治疗后临床症状及体征较治疗前均显著改善,且治疗组患者临床症状及体征较对照组患者改善更显著,两组比较差异有统计学意义（P〈0．05）。两组患者不良反应发生率比较差异无统计学意义（P〉0．05）,且治疗期间两组患者肝、肾功能和血常规均无明显变化。结论：血必净注射液联合左氧氟沙星治疗泌尿系统感染,疗效及安全性均较好。