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目的 探讨和完善鼻内窥镜下彻底切除鼻内翻性乳头状瘤,降低术后复发率的手术方法及其适应证。方法 1993年2月至2002年6月住院的临床及病理诊断为鼻内翻性乳头状瘤48例,其中30例有1~4次前期经鼻或鼻侧切开手术史。37例患者采用鼻内窥镜经鼻肿瘤切除术;11例患者肿瘤侵及中鼻道、上颌窦口和部分或全部筛窦外,同时广泛侵及上颌窦内采用鼻内窥镜经鼻肿瘤切除,同时在内窥镜下经上颌窦前壁或下鼻道开窗联合径路肿瘤切除术,全部病例随访10~36个月。结果 48例中1例术后复发,47例未复发,治愈率97.9%。8例(16、7%)术后换药期间发现术腔局部出现瘤样组织,病理证实为内翻性乳头状瘤,内窥镜下以YAG激光处理局部创面,随诊18个月,未再发现有瘤样组织。结论 辅以YAG激光治疗的内窥镜经鼻内翻性乳头状瘤切除术,有利于彻底切除肿瘤,该术式避免了面部疤痕,但对肿瘤已广泛侵及上颌窦内者宜采用联合径路术。 相似文献
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目的 研究微创下手术切除鼻腔鼻窦内翻性乳头状瘤的治疗效果。方法 对25例鼻腔鼻窦内翻性乳头状瘤的患者施行鼻内窥镜下手术,术中配合使用电动吸切器切除肿瘤,术后随访12~60个月。结果 全部25例均在鼻内窥镜下一次完整切除肿瘤。25例中2例分别于术后12个月和16个月内复发,其余23例在随访期内未见复发。结论 使用鼻内窥镜微创下行鼻腔鼻窦内翻性乳头状瘤切除不仅对病变局限者有效,对病变广泛侵犯后组筛窦和蝶窦者亦有较好疗效。但对瘤体广泛浸及上颌窦或额窦者宜采用联合径路实施手术。 相似文献
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目的 研究微创下手术切除鼻腔鼻窦内翻性乳头状瘤的治疗效果。方法 对 2 5例鼻腔鼻窦内翻性乳头状瘤的患者施行鼻内窥镜下手术 ,术中配合使用电动吸切器切除肿瘤 ,术后随访 12~ 60个月。结果 全部 2 5例均在鼻内窥镜下一次完整切除肿瘤 ,2 5例中 2例分别于术后 12个月和 16个月内复发 ,其余 2 3例在随访期内未见复发。结论 使用鼻内窥镜微创下行鼻腔鼻窦内翻性乳头状瘤切除不仅对病变局限者有效 ,对病变广泛侵犯后组筛窦和蝶窦者亦有较好疗效。但对瘤体广泛浸及上颌窦或额窦者宜采用联合径路实施手术。 相似文献
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目的探讨经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术和鼻内镜联合鼻侧切开鼻腔鼻窦内翻性乳头状瘤切除术的疗效。方法26例鼻腔鼻窦内翻性乳头状瘤病例中,22例行经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术,4例行鼻内镜联合鼻侧切开鼻腔鼻窦内翻性乳头状瘤切除术。结果术后随访9~60个月。1例术后30个月复发,其它25例未见复发,全部病例无并发症发生。结论经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术适用于较局限的病变,而对广泛病变则应采用鼻内镜联合鼻侧切开术,术后鼻内镜定期复查可早期发现肿瘤复发并处理。 相似文献
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目的探讨经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术和鼻内镜联合鼻侧切开鼻腔鼻窦内翻性乳头状瘤切除术的疗效。方法26例鼻腔鼻窦内翻性乳头状瘤病例中,22例行经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术,4例行鼻内镜联合鼻侧切开鼻腔鼻窦内翻性乳头状瘤切除术。结果术后随访9~60个月。1例术后30个月复发,其它25例未见复发,全部病例无并发症发生。结论经鼻内窥镜鼻腔鼻窦内翻性乳头状瘤切除术适用于较局限的病变,而对广泛病变则应采用鼻内镜联合鼻侧切开术,术后鼻内镜定期复查可早期发现肿瘤复发并处理。 相似文献
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目的:研究孤立性蝶窦肿瘤的诊断和治疗。方法:6例孤立性蝶窦肿瘤,全部病人均有头痛症状,其中5例有眼-神经症状,所有病人均经CT证实为孤立性蝶窦占位性病变,并在鼻内窥镜下取病检。其中良性2例,包括乳头腺瘤1例,内翻性乳头状瘤1例。恶性肿瘤4例,包括蝶窦低分化鳞癌2例,腺样囊性癌1例,内翻性乳头状瘤恶变1例。1例乳头状腺瘤行鼻内窥镜下蝶窦开放术,其余5例经鼻外筛窦径路手术。结果:2例良性肿瘤中,1例乳头状瘤治愈随访40月,1例内翻性乳头状瘤手术后随访15月症状改善。4例恶性肿瘤中3例术后放疗观察18-28月无复发。1例失访。结论:鼻内窥镜、影像学检查对本病的诊断起重要作用,并对手术有指导意义。良性肿瘤以鼻内窥镜手术为主。恶性肿瘤以手术加放疗治疗,鼻外筛窦径路是治疗此类恶性肿瘤的优选术式。 相似文献
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目的:探讨鼻内窥镜下电凝电刀手术治疗鼻腔内翻性乳头状瘤的方法和初步疗效。方法:对2008年11月至2010年12月诊治的20例鼻腔内翻性乳头状瘤的临床资料进行回顾性分析,全部患者均接受鼻内窥镜下鼻腔乳头状瘤切除术的手术方案。按Krouse分级,其中1级局限于鼻中隔患者3例和2级病变位于鼻腔上颌窦口周围患者10例,病变侵及筛窦5例,均全程采用电凝电刀完成手术治疗,属3级病变的既往手术复发者2例,病变累及全组鼻窦伴轻度骨质破环2例,采用电刀电凝结合电动吸切器完成手术治疗,手术过程均在全麻鼻内窥镜下进行。结果:除2例复发的属3级病变的鼻腔乳头状瘤病例,均完成肿瘤根治切除,术中出血较少,除2例复发性内翻性乳头状瘤患者出血约150ml外,其余18例原发性患者出血量为10-50ml,中位数出血量35ml。手术时间短,为20-60min,术中术野清晰,无颅-额-眶手术并发症,术后1天抽取纱条,3天后出院,3个月后复查见术腔完全上皮化。随访3-6个月,中位随访时间4个月,20例鼻腔乳头状瘤病例术前鼻塞,血性脓涕,头痛等症状均缓解,无复发病例。结论:电凝电刀手术治疗鼻腔内翻性乳头状瘤具有手术损伤小,手术时间短,手术视野清晰,对病变的基底及安全边缘切除彻底,不易造成瘤组织的血行播散,术中及术后出血少,围手术期不良反应轻,术后不易复发等优点,对于1级和2级病变可做到肿瘤完整切除,是一种较好的微创治疗鼻腔内翻性乳头状瘤的方法。 相似文献
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目的:探讨鼻内窥镜下电凝电刀手术治疗鼻腔内翻性乳头状瘤的方法和初步疗效。方法:对2008年11月至2010年12月诊治的20例鼻腔内翻性乳头状瘤的临床资料进行回顾性分析,全部患者均接受鼻内窥镜下鼻腔乳头状瘤切除术的手术方案。按Krouse分级,其中1级局限于鼻中隔患者3例和2级病变位于鼻腔上颌窦口周围患者10例,病变侵及筛窦5例,均全程采用电凝电刀完成手术治疗,属3级病变的既往手术复发者2例,病变累及全组鼻窦伴轻度骨质破环2例,采用电刀电凝结合电动吸切器完成手术治疗,手术过程均在全麻鼻内窥镜下进行。结果:除2例复发的属3级病变的鼻腔乳头状瘤病例,均完成肿瘤根治切除,术中出血较少,除2例复发性内翻性乳头状瘤患者出血约150ml外,其余18例原发性患者出血量为10-50ml,中位数出血量35ml。手术时间短,为20-60min,术中术野清晰,无颅-额-眶手术并发症,术后1天抽取纱条,3天后出院,3个月后复查见术腔完全上皮化。随访3-6个月,中位随访时间4个月,20例鼻腔乳头状瘤病例术前鼻塞,血性脓涕,头痛等症状均缓解,无复发病例。结论:电凝电刀手术治疗鼻腔内翻性乳头状瘤具有手术损伤小,手术时间短,手术视野清晰,对病变的基底及安全边缘切除彻底,不易造成瘤组织的血行播散,术中及术后出血少,围手术期不良反应轻,术后不易复发等优点,对于1级和2级病变可做到肿瘤完整切除,是一种较好的微创治疗鼻腔内翻性乳头状瘤的方法。 相似文献
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目的:通过总结28例经鼻内镜下手术治疗的鼻腔鼻窦内翻性乳头状瘤临床经验,探讨不同分期的鼻腔、鼻窦内翻性乳头状瘤鼻内镜下手术治疗的优选方法以及预防复发经验。方法: 回顾性分析28例2015年1月-2017年1月我院住院的临床及病理诊断为鼻腔鼻窦内翻性乳头状瘤的患者,其中采用单纯鼻内镜下经鼻腔、鼻窦肿瘤切除术22例,鼻内镜联合泪前隐窝入路4例,鼻内镜联合眉弓入路(Lynch切口)1例,鼻内镜联合上颌窦前壁进路(Caldwell-luc)1例。结果:28例患者痊愈20例,复发8例,复发患者中T2期7例,T3期1例,复发率29%。结论:鼻腔鼻窦内翻性乳头状瘤需根据分期及不同病变部位选择不同手术方法,T1期、T2期患者可单纯鼻内镜下完成彻底切除,必要时联合泪前隐窝入路;T3期患者,病变位于额窦可鼻内镜联合眉弓进路手术(Lynch切口)或DrafⅡb、DrafⅢ型[1],病变位于上颌窦可鼻内镜联合泪前隐窝入路或鼻内镜联合Caldwell-luc术式,T1、T2期患者疗效优于T3期患者。术后需长期随访观察,若有复发需尽早切除并电凝或等离子行病变处局部治疗。 相似文献
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目的 探讨鼻内镜手术治疗鼻腔鼻窦内翻性乳头状瘤(SNIP)的临床效果.方法 回顾性分析93例行鼻内镜手术治疗的SNIP患者的临床资料,对患者进行Krouse分期,比较不同手术方法(单纯鼻内镜手术、鼻内镜联合改良柯-陆氏手术、鼻内镜联合鼻外进路手术)的治疗效果及术后复发情况.结果 所有患者均一次性完成手术,手术时间47~196 min,平均(94.3±25.9)min;术中出血量34~281 ml,平均(97.3±29.0)ml;术后随访时间26~62个月,平均(39.4±10.9)个月.19例KrouseⅠ期患者均采用单纯鼻内镜手术治疗,复发1例(5.26%).45例KrouseⅡ期患者中,32例采用单纯鼻内镜手术治疗,复发2例(6.25%);13例采用鼻内镜联合改良柯-陆氏手术治疗,复发1例(7.69%),两种手术方法的复发率比较,差异无统计学意义(P>0.05).25例KrouseⅢ期患者中,10例采用单纯鼻内镜手术治疗,复发6例(60.00%);15例采用鼻内镜联合改良柯-陆氏手术治疗,复发1例(6.67%),两种手术方法的复发率比较,差异有统计学意义(P<0.05).4例KrouseⅣ期患者均采用鼻内镜联合鼻外进路手术治疗,复发1例(25.00%).结论 鼻内镜手术治疗SNIP效果较好,复发率低,应根据患者肿瘤分期制定手术方案,并于术后定期复查以有效预防肿瘤复发. 相似文献
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背景与目的:对于放疗后鼻咽局限性残留、复发鼻咽癌,二程放疗可以使部分患者得到长期局部控制,但其放射性后遗症也相当严重:而救援性外科手术在取得相仿甚至更优疗效的同时,避免了这些放射性后遗症.然而,传统开放式手术进路创伤大,术野欠清晰,难以按肿瘤外科原则进行连续、整块切除.本研究旨在探索一种新的微创性鼻内镜进路的复发鼻咽癌外科治疗方法.方法:从2004年9月至2007年1月,25例放疗后鼻咽局限性残留或复发鼻咽癌患者在中山大学肿瘤防治中心进行经鼻内镜鼻咽切除术,将鼻咽肿瘤和足够的安全边缘连续、整块切除.观察其疗效和并发症.结果:25例患者均在鼻内镜进路下按肿瘤外科手术原则进行根治性整块切除,仅1例切缘阳性,鼻咽创面愈合良好,均未追加术后放疗.中位随访时间13个月(3~31个月),1例原位残留,3例术后原位复发,无远处转移和死亡.1年总生存率100%,无局部复发生存率达86.0%.无张口、吞咽、发音困难和其他手术并发症发生,无围手术期死亡.结论:鼻内镜进路鼻咽癌救援手术能充分暴露鼻咽以及咽旁间隙浅部,能将鼻咽残留、复发病灶按肿瘤外科原则进行连续、整块根治性切除,并发症少而轻,近期疗效满意. 相似文献
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Endoscopic Modified Danker’s Approach for Management of Sinonasal Inverted Papilloma: Our Experience
Brajendra Baser Ankit Mishra Priya Chaubey 《Indian journal of otolaryngology and head and neck surgery》2021,73(3):282
Sinonasal inverted papilloma (SNIP), Inverting papilloma, Schneiderian papilloma etc. It is a benign tumor with incidence nearly 70% of all sinonasal papilloma and 0.5–4.0% of all sinonasal neoplasms. The most common site of origin is lateral nasal wall and common presenting symptom is nasal obstruction followed by epistaxis. On histopathology examination, it is characterized by invagination of neoplastic epithelium into underlying stroma. With the advent of technology, the endoscopic modified dankers approach became the surgical approach of choice. The present study was undertaken to study its role in management of SNIP with reference to rate of recurrence and malignancy. An observational study was conducted in a tertiary health center in which 40 biopsy proven cases of SNIP, operated by endoscopic assisted modified Danker’s approach between September 2008 and January 2019 with minimum follow-up period of 6 months were analyzed. Male:Female ratio was 2.33:1. The most common symptom was nasal obstruction (97.5%) followed by rhinorrhoea (87.5%). Using various imaging and diagnostic measures, lateral nasal wall was found to be the most common site of origin. Out of total 40 cases, 9 (27.5%) patients had recurrence, of these, 6 were benign and remaining 3 had malignancy as confirmed by biopsy. Most of the cases of SNIP can be managed endoscopically, although extensive lesions or the lesions with malignant transformation, external approach may be needed so expertise in both endoscopic and conventional techniques is needed. Although most of the recurrences occurred in first 2 years, but life time follow-up is advisable. 相似文献
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Nagendra P. B. Kadapa L. Sudarshan Reddy Venkataram Reddy P. Kumuda M. Vishnu Vardhan Reddy L. M. S. Chandra Sekhara Rao 《Indian journal of otolaryngology and head and neck surgery》2014,66(2):200-204
Sinonasal inverted papillomas (SIP) are unique group of locally aggressive benign neoplastic lesions arising from mucosa of sinonasal tract with potential for recurrences and known association with squamous cell carcinoma in 5–15 % of cases. This study was conducted was to assess the efficacy and usefulness of the nasal endoscope in treating SIP. We reviewed 28 biopsy proven cases of SIPs that were treated at our hospital between June 2009 and September 2013. Average patient age was 46 years. Fourteen were treated by transnasal endoscopic excision of tumor with noted recurrence of 21.43 %. Thirteen were treated by endoscopic assisted open surgery which had 23 % recurrence. Three patients had malignant inverted papillomas, of whom two (7 %) were found to have synchronous squamous cell carcinoma and one (3.6 %) had metachronous squamous cell carcinoma. No evidence of recurrence was found in rest during our follow up. The endoscopic approach is the preferred method for the treatment of the majority of inverted papillomas. Powered instrumentation is extremely useful to achieve good results. Although significant number of cases was done by external approach by lateral rhinotomy, the endoscopic assistance is required to ensure complete removal of the tumour to reduce the recurrence rates. Close follow up of the patient for a longer period of time is necessary for the early detection of recurrence and to allow for surgical salvage. 相似文献
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[目的]探讨经胃镜高频电切除术对食管微小平滑肌瘤诊断及治疗的意义.[方法] 54例食管微小平滑肌瘤患者,其中49例行高频电切除治疗,2例行外科手术治疗,3例随访观察.术后常规送切除组织行病理检查.[结果]在50例获得病理诊断中,确诊食管平滑肌瘤47例.临床诊断食管微小平滑肌瘤的符合率为94.0%(47/50),高频电切除成功率为90.7%(49/54).高频电切除治疗术后患者无食管穿孔等严重并发症发生,创面渗血2例(2/49);30例患者术后1个月~2年复查胃镜未见病变再发.[结论]胃镜下高频电切除微小食管平滑肌瘤安全、有效,有助于明确诊断,又可使其获得治疗. 相似文献
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Background and Study Aims Advanced neoplasia may occur in the remaining colon and distal ileum of familial adenomatous polyposis (FAP) patients who
have had a prophylactic colon resection. The role of post operative lower GI endoscopic surveillance and management of advanced
neoplasia in FAP patients is not well defined. The aims of this study were to determine the prevalence of post operative neoplasia
and to evaluate the safety and effectiveness of lower GI endoscopic surveillance and ablative therapy following prophylactic
colon resection. Patients and Methods A retrospective analysis of 42 FAP patients with prior primary colon cancer preventative surgery undergoing lower GI surveillance
and ablative therapy from 1992 to 2006. Results All patients had adenomatous disease identified upon initial endoscopy with advanced neoplasia identified in 6/42 (14%).
Patients had a median of 4 endoscopic procedures of which 2 (range 0–12) were therapeutic, over a 49 month follow-up period
(range 0–168) Thermal ablation with argon plasma coagulation, polypectomy and surgical intervention were required in 55%,
7% and 14% of patients. Ablative therapy complications were due to Nd: YAG laser and snare polypectomy (5%). Progression to
advanced neoplasia from baseline pathology occurred despite ablative therapy in 3/42 (7%) patients. We propose a lower GI
tract endoscopic surveillance program for post surgical FAP patients. Conclusion Despite prophylactic colon surgery, FAP patients continue to be at risk of neoplasia. The development of advanced neoplasia
is infrequent in patients embarking upon endoscopic surveillance. Ablative therapy is effective and safe for the vast majority
of FAP patients. 相似文献