Clinical controlled study of integrative Chinese and western medicine in treating 49 cases of SARS

Objective:To evaluate the efficacy of integrative Chinese and western medicine(ICWM)in treating severe acute respiratory syndrome(SARS)patients.Methods:Through parallel control design,49 SARS patients were observed.Used as control,there were in the western medicine(WM)group 29 pa-tients,who were treated with Ribavirin,Levofloxacin,Thymopentin,Azithromycin,methylprednisolone,etc.,on the basis of“Recommended Protocol for Infectious Atypical Pneumonia”(abbreviated as“Recom-mended Protocol”)issueed by Ministry of Health.As the treated group,there were in the ICWM 20 ca-ses.The protocol for treatment of SARS in“Special Science and Technological Action to Prevent andTreats SARS”(abbreviated as“Special S-T Action”),issued by Ministry of Science and Technology,to-gether with the same WM as those for the control group.Results:(1)Time from the disease onset to thesymptom improvement were 5.10±2.83 days and7.62±2.27 days ICWM and WM group respectively,P<0.05;(2)As to corticosteroid(CS)amount and days bef     

Therapeutic Effect of Integrative Traditional Chinese and Western Medicine on 51 SARS Patients and Its Influence on Their TLymphocyte Subsets

Severeacuterespiratorysyndrome(SARS)isanewlyariseninfectiousdiseasewithrespiratorytractasthechiefpathwayoftransmission.Thisisespecial lytrueforSARSpatientsofseveretypeduetoitsse riouscondition,whichresultsinhighmortalityandgreatdifficultiesinitstreatment.InordertoexploretheeffectivewaysintreatmentofSARS,clinicalstudiesontreatmentofSARSbyintegrativeChineseandwesternmedicine(ICWM)havebeencarriedoutbytheauthorsandthepreliminarysummaryisre portedasfollows.METHODSClinicalMaterials　　 T…     

Clinical Characteristics of 42 SARS Patients and Their Treatment of Integrative Chinese and Western Medicine

Objictive:To understand the clinical manifestation of severe acute respiratory syndrome(SARS)and explore its effective treatment with integrative Chinese and western medicine(ICWM).Methods:The data of patients,whose diagnosis of SARS had been confirmed were summarized and ana-lyzed,and clinical observation was conducted when the patients were treated with ICWM.Results:In theearly stage of the 42 patients,the symptoms revealed were fever in 100％ of SARS patients,headache in92.9％,aversion to cold in 76.2％,chest stuffiness in 76.2％,cough in 73.8％and myalgia in 88.1％;Pulmonary lesion Involves ≥3 lobes in 42.9％,2 lobes in 47.6％ and 1 lobe in 9.5％;61.9％ of themshowed liver function abnormality(increase of ALT or AST),47.6％ showed elevated myocardial enzyme(CK or CK-MB),0.48％ showed an inclination of renal function(higher of BUN or Cr);in their T lym-Phocyte subsets,91.2％(31/34 Patients)had lowered CD_3 and 76.5％(26/34 Patients)lowered CD_4/CD_8ratio.In the mid-late stage,the symptoms were lass     

Clinical Observation on Chinese and Western Integrative Medicine in Treating Repeatedly Recurrent Chronic Pyelonephritis

Ｕｒｉｎａｒｙｔｒａｃｔｉｎｆｅｃｔｉｏｎｉｓａｃｏｍｍｏｎｄｉｓ ｅａｓｅｏｆｕｒｉｎａｒｙｓｙｓｔｅｍ，ｉｔｓｒｅｌａｐｔｉｃａｎｄｒｅｃｕｒ ｒｅｎｔｒａｔｅｗｅｒｅｖｅｒｙｈｉｇｈ，ｐａｒｔｉｃｕｌａｒｌｙｆｏｒｔｈｅｍａｒｒｉｅｄａｄｕｌｔｆｅｍａｌｅ，ａｇｅｄａｎｄｗｅａｋｉｎｄｉｖｉｄｕ ａｌｓａｓｗｅｌｌａｓｔｈｏｓｅｗｉｔｈｃｏｍｐｌｉｃａｔｅｄｕｒｉｎａｒｙｃｏｎｄｉｔｉｏｎｓ．Ｉｔｗａｓｏｆｔｅｎｍａｎｉｆｅｓｔｅｄａｓａｆｒｅ ｑｕｅｎｔｌｙｒｅｃｕｒｒｅｎｔｐｒｏｃｅｓｓ．…     

Effects of Integrative Chinese and Western Medicine on Arterial Oxygen Saturation in Patients with Severe Acute Respiratory Syndrome

Objective: To evaluate the effects of treatment of integrative Chinese and Western medicine (ICWM) on arterial oxygen saturation (SaO2) in patients with severe acute respiratory syndrome (SARS). Methods:The non-randomized, controlled trial was conducted on 447 SARS patients treated synchronously with western conventional treatment (WM group, n = 171) alone and ICWM (ICWM group, n = 276). The changes of the cases with normal level (≥95% ) or abnormal level (<95% ) SaO2 were observed dynamically. Results: In the 3rd-14th day of the therapeutic course, the percentage of patients with normal SaO2 in the ICWM group was higher than that in the WM group (OR = 0.5178, P = 0.0038), and this tendency was more evident in patients of the severe type (OR = 0. 18, P = 0. 0001). However, the statistical significance of difference was only shown in patients for whom the ICWM treatment started in the early period after the onset (≤7 days after it, OR = 0.3803, P = 0.006), but not shown in those who received ICWM treat     

Clinical progress in the treatment of severe acute pancreatitis with integrative Chinese and Western medicine

Severe acute pancreatitis (SAP),one of the crucial acute abdominal diseases,has high mortality for its quick initiation,severe condition,long duration,and frequent complication with multiple organ failure.In this paper,the clinical progress in the treatment of SAP with integrative Chinese and Western medicine is inspected and summarized.     

240例SARS患者T淋巴细胞及活化亚群的变化

目的研究严重急性呼吸综合征(severeacuterespiratorysyndrome,SARS)患者外周血T淋巴细胞及其活化亚群的变化情况。方法采用多色荧光标记流式细胞术结合血液分析仪,检测240例不同病程的SARS患者(包括50例重型患者和190例普通型患者)的外周血T淋巴细胞及其活化亚群的表达情况。结果在年龄、性别无显著差异时,与正常对照组比较,SARS患者的外周血T淋巴细胞及其各活化亚群绝对值明显减低,其中CD3+CD25+、CD3+HLA-DR亚群百分比升高;与普通型患者比较,重型患者T细胞、CD4+亚群的绝对值均明显减低,CD25+CD3+、CD28+CD4+及CD95+CD4+亚群的绝对值也明显降低;各病程SARS患者比较,T淋巴细胞(包括CD4、CD8亚群)的绝对值为Ⅲ组>Ⅱ组>Ⅰ组;CD25+CD3+、CD28+CD4+及CD95+CD4+亚群的绝对值也明显降低。结论伴随着全面低下的细胞免疫功能,SARS患者的T细胞有效活化过程有所改变,以重型SARS患者尤其明显。     

中西医结合治疗骨折延迟愈合临床疗效观察

目的探讨中西医治疗骨折延迟愈合的疗效。方法200例骨折延迟愈合患者平均随机分为实验组和对照组,均予切开复位,钢板固定,实验组加用中药方剂内服,观察两组的骨折愈合效果。结果两组骨折延迟愈合患者治疗4个月盾治疗效果经秩和检验比较,差异有统计学意义（1t=7．11,P〈0．05）,实验组愈合率为90％,对照组愈合率为40％,差异有统计学意义（χ2=8．23,P〈O．05）。治疗后不同时间点实验组治疗起效人数比例（40％、75％、96％、100％）均高于对照组（20％、40％、70％、80％,P〈0．05）。术后随访12个月,实验组全部愈合,平均愈合时间（60．5=10．3）d,对照组90例愈合,平均愈合时间（109．2±12．3）d,实验组愈合时问显著短于对照组（P〈0．05）。结论中西医结合治疗骨折延迟愈合效果肯定,能显著增加总体骨折愈合率,加快愈合速度,缩短骨折愈合时间,提高骨折治疗效果及患者生活质量。     

中西医结合治疗SARS杂谈

中西医结合治疗严重急性呼吸综合征(severe acute respiratory syndrome，SARS)有明显优势，结合古今文献和SARS的特殊流行规律、病理特点和临床表现，提出了中西医结合治疗SARS的思路和方法，以及临床应用时应该注意的几个问题。     

Therapeutic Effects of Integrated Traditional Chinese Medicine and Western Medicine in Treating Severe Acute Respiratory Syndrome

Severeacuterespiratorysyndrome(SARS)isanacuteinfectiousdiseasecausedbyanewkindofcoro navirus,andasitisstronglyinfective,highlymortalandliabletoaffecthumanbeings,itseverelythreat enshumanhealth,influencestheirdailylifeandpro ductiveactivity.Now,themicrobiologicalcharacter isticsofSARSrelatedvirusanditsinfectionmecha nismarebeingdeeplystudiedbuttherehasbeennospecifictreatmentforSARSfoundsofar.Inordertoelevatethetherapeuticeffects,lightenpatients'symptoms,improvethepulmonaryinflammationandcel…     

SARS患者T淋巴细胞亚群的动态改变

目的研究严重急性呼吸综合征(severeacuterespiratorysyndrome,SARS)患者T淋巴细胞亚群动态变化的特点。方法收集本院确诊的46例SARS患者在发病后不同时间的抗凝血,用特异性荧光抗体标记,通过三色流式细胞仪检测其T淋巴细胞亚群、CD4+纯真细胞亚群(CD4+CD45RA+CD62L+)和CD8+激活亚群(CD8+CD38+),以56例健康献血员的结果作为正常人对照。结果与正常对照相比,SARS患者的CD4+细胞和CD8+细胞在感染1周内百分比正常,但计数均显著减少,分别为(306±140)/mm3和(270±143)/mm3,CD4+纯真细胞亚群的计数也明显降低至(96±49)/mm3,CD8+CD38+激活亚群的比例则明显升至(59.3±12.6)%犤正常人为(44.9±12.5)%犦。感染3～5周时,CD8+细胞计数和激活亚群的百分比均恢复正常,分别为(581±356)/mm3和(40.1±17.6)%。感染8～12周时,CD4+细胞和CD4+纯真细胞亚群的计数分别为(578±193)/mm3和(176±64)/mm3,仍低于正常水平,但与感染1周时相比均有异常显著的升高。结论SARS患者的T淋巴细胞免疫在细胞数量上严重受损,但在短期内有很明显的恢复,CD4+细胞和纯真CD4+细胞亚群的恢复需要比8～12周更长的时间。     

中西医结合治疗痛风患者临床疗效观察及安全性评价

目的：探讨中西医结合治疗痛风患者临床疗效观察及其安全性评价。方法选自2014年1月至2015年1月期间收治的92例痛风患者,依据随机数字表法随机分为治疗组46例与对照组46例。治疗组采用中西医结合治疗,对照组仅采用西医治疗。2组疗程均为10 d。比较2组患者治疗总有效率,治疗后关节疼痛缓解时间和关节红肿时间,治疗前后血清白介素－1β（ IL－1β）、 C 反应蛋白（ CRP）、血沉（ ESR）水平变化及治疗期间不良反应发生情况。结果治疗组总有效率（95．65％）高于对照组（76．09％）（ P＜0．01）;治疗组关节疼痛缓解时间和关节红肿时间明显优于对照组（ P＜0．05）;2组血清 IL－1β、 CRP、 ESR 治疗后明显下降（ P ＜0．05）;治疗组血清 IL－1β、CRP、 ESR治疗后低于对照组（P＜0．05）;治疗期间2组均未见严重药物不良反应。结论中西医结合治疗痛风患者临床疗效显著,且安全可靠,具有重要研究意义。     

95例SARS患者T细胞及其亚群动态变化的观察

对 95例SARS患者的T淋巴细胞亚群动态变化进行分析。其中 85例痊愈 ,1 0例死亡。 85例痊愈患者 ,病程第 7天平均CD4 + ( 3 2 5± 1 90 )个 /μL ,CD8+ ( 3 1 9± 3 1 5 )个 /μL ,CD4 + /CD8+ 1 .2 5± 0 .71 ,与我国正常人相比〔平均CD4 + ( 72 7± 2 5 5 )个 /μL、CD8+ ( 5 3 9± 1 3 4)个 /μL ,CD4 + /CD8+ 1 .49〕 ,T淋巴细胞亚群明显下降 (P =0 .0 0 1 )。病程第1 4天左右免疫功能逐渐恢复 ,平均CD4 + ( 5 61± 5 2 2 )个 /μL ,CD8+ ( 3 70± 2 71 )个 /μL ,CD4 + /CD8+ 1 .68± 1 .1 1。 2 1d后免疫功能基本恢复正常 ,平均CD4 + ( 675± 448)个 /μL ,CD8+ ( 4 67± 2 41 )个 /μL ,CD4 + /CD8+ 1 .48± 0 .68。 1 0例死亡患者的T细胞亚群在入院后逐渐出现下降趋势 ,病程第 7天CD4 + ( 2 48± 82 )个 /μL ,CD8+ ( 2 3 3± 1 1 5 )个 /μL ,CD4 + /CD8+ 1 .2 1± 0 .40 ,第 1 4天T淋巴细胞继续下降 ,平均CD4 + ( 1 81± 1 2 8)个 /μL ,CD8+ ( 1 73± 1 0 9)个 /μL ,CD4 + /CD8+ 1 .1 7± 0 .45 ,2 1d后CD4 + 细胞继续下降 ,平均CD4 + ( 1 2 5± 46)个 /μL ,CD8+ ( 94± 3 8)个 /μL ,CD4 + /CD8+ 1 .44±0 .5 9。结果提示 :SARS患者早期可能存在异常的免疫反应 ,这种异常免疫反应可能是导?     

The model of western integrative medicine: The role of Chinese medicine

The basic concept of integrative medicine(IM) is that by combining mainstream(biomedicine) with complementary and alternative medicine(CAM), synergistic therapeutic effects can be attained.When the methods of mind/body medicine(MBM) are added to this combination,as in Western countries,a new concept emerges that drastically changes the approach toward illness. It is interesting to note that the joining of traditional Chinese medicine and Western medicine in the early days of the Peoples’ Republic of China preceded the Western model of IM by almost 50 years.Several elements that make up the key components of IM as practiced today in the West were already present in the Chinese version of IM,and Chinese medicine has played and continues to play an important role in advancing IM.However,one of the major differences between the Chinese and the Western models of IM today,besides MBM and some other treatment options,is that Western integrative medicine(WIM) strictly requires its CAM methods to be supported by scientific evidence. The therapeutic methods of IM and their applications are many and varied.However,they are most frequently employed to treat chronic medical conditions,e.g.,bronchial asthma,rheumatic disease, chronic inflammatory bowel disorder and chronic pain.Other fields in which IM may be applied are internal medicine(inflammatory bowel diseases and cardiovascular diseases),musculoskeletal disorders,oncology (chemotherapy-induced side effects),obstetrics and gynecology(dysmenorrhea,endometriosis,infertility and menopausal complaints),pediatrics,geriatrics,neurology(migraine and chronic headache),and psychiatry (anxiety and depression). The concept of WIM is discussed here in detail by reviewing its scope and implications for the practice of medicine and focusing on the role of Chinese medicine in WIM.     

从急性感染性疾病的临床诊治谈中西医结合

急性感染性疾病是严重威胁人类健康的常见病、多发病。近年来医疗界面临空前严峻的细菌耐药形势,而新药研发的速度远远赶不上耐药菌的发展速度。在严重感染诊治过程中注重脏器保护、改善微循环,是提高救治率的关键。我们在中西医结合理论指导下,采用西医辨病、中医辨证,中西医优势互补、病证结合的原则诊治急性感染性疾病,取得明显的临床疗效。通过多中心前瞻性临床研究,总结出实热证(热夹湿型、热盛伤阴型)、血瘀证、腑气不通证和厥脱证。通过实验研究,证实了中药在急性感染性疾病的细菌耐药、脏器保护、微循环等方面的作用。中西医结合是治疗急性感染性疾病的最佳策略,突破中西医之间的壁垒是关键,病证结合、方证对应是中西医结合治疗的切入点。     

A survey on treatment of dry eye by traditional chinese medicine and integrative Chinese and Western medicine

Dryeyeisadisorderoftearfilmduetotear deficiencyorexcessivetearevaporationcausingdamagetotheinterpalpebralocularsurfaceandas sociatedwithsymptomsofoculardiscomfort(1).As itisnowoneofthemostcommonsuperficialdisor dersinophthalmologyintheworldaswellasinChi na,moreandmorepeopleattachimportancetothe study.ThetreatmentofdryeyebytraditionalChi nesemedicine(TCM)orintegrativeChineseandWesternmedicine(ICWM)isnowreviewedinthis paper.TREATMENTOFDRYEYEBYTCMANDICWMTHERAPY LocalTreatmentwi…     

Treatment of severe post-kidney-transplant lung infection by integrative Chinese and Western medicine

Lunginfection is one of the most common post-kidney-transplant complications . About 70 % of thepost-kidney-transplant patients develop infectionswithin one year of operation(1),of which the rate oflung infection within 1 -3 months were the highest ,and apparently affected survival rate. Severe lunginfection with its severe symptoms ,complex statusand rapid clinical course,is one of the main causesforthe death rate among kidney transplant receivers. Themortalityis even as high as 23 .8 %-52 .0…     

髌骨软化症中西医治疗进展

髌骨软化症是一种髌骨软骨退行性病变,西医治疗早中期主要提倡保守治疗,包括关节腔内注射玻璃酸钠、口服硫酸氨基葡萄糖、非甾体类抗炎药等;晚期建议手术治疗,均有一定效果及毒副作用.中医认为本病多因伤后气血不足,瘀血阻滞风寒湿邪侵袭,或因年老体弱,肝肾亏虚,气血亏虚,卫外不固,不能濡润关节,风寒湿邪乘虚而入而发病,治疗主要有中药内服、外敷、熏洗、针灸、推拿等法,急则治其标,缓则治其本,因人制宜,标本兼顾.中西医结合治疗可取长补短.     

中西医结合治疗代谢综合征的临床疗效

目的观察恩施州少数民族地区我院自制中药降脂活血片联合常用西药治疗代谢综合征（metabolic syndrome,MS）的临床疗效。方法将72例代谢综合症患者随机分为两组,均常规口服西药罗格列酮、非诺贝特片为对照组,治疗组加用我院自制中药降脂活血片。治疗前、治疗12周后分别观察肥胖指数（BMI）、空腹血糖（FBG）、谷丙转氨酶（GPT）、总胆固醇（TC）、三酰甘油（TG）、高、低密度脂蛋白（HDL、LDL）、胰岛素抵抗指数（IRI）、血压等指标变化情况。结果治疗12周后,两组患者BMI、IRI指数下降,血脂TC、TG、LDL水平均降低,HDL均升高（P〈0.05）,与对照组比较,治疗组效果更显著（P〈0.05）。临床治疗总有效率治疗组为92.86%,对照组为73.33%,两组比较差异有统计学意义（P〈0.05）。结论降脂活血片具有降脂、抗凝、抑制血小板聚集、降低血液黏度的作用,临床研究证实降脂活血片联合罗格列酮、非诺贝特治疗对代谢综合征患者比单用西药更有效,可显著改善患者血脂、血糖,维持血压稳定和减轻胰岛素抵抗,且无明显副作用。     

中西医结合治疗复发性口腔溃疡的循证评价

目的应用Meta分析法评价中西医结合治疗复发性口腔溃疡的临床疗效。方法计算机检索1990年—2011年发表的有关中西医结合治疗复发性口腔溃疡的文献,采用Review Manager 5.0软件进行数据分析。结果共检索到12篇相关文献,其中7篇为随机对照试验,2篇为单个病例-对照试验,3篇为随机化不明确的同期对照试验。上述文献研究结果显示,目前有足够的证据支持能够用于治疗复发性口腔溃疡的方法有戒除吸烟、口服抗生素预防继发感染、中西医结合治疗。中西医结合治疗复发性口腔溃疡显示出较单纯使用西药治疗更加满意的疗效,临床应根据具体情况和条件选择合适的治疗方法。结论基于循证理论,采用中西医结合治疗复发性口腔溃疡可确切提高临床疗效。