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1.
MAIN PROBLEM: There is an increasing presence of a population of British and Irish origin in southeastern Spain. Hypothesis: this population native from countries with higher rates of living kidney donation than Spain will be very much in favour of related living kidney donation. OBJECTIVE: to analyse the attitude of this population subgroup towards living kidney donation. METHODS: Between November 2005 and April 2006, a random sample was taken of British and Irish residents in southeastern Spain (n = 1700) and stratified by the respondent's nationality. Attitude was evaluated using a validated questionnaire that was completed anonymously and self-administered. RESULTS: The questionnaire completion rate was 90% (n = 1533). Ninety percent (n = 1384) are in favour of related living kidney donation, 9% (n = 138) are against and the remaining 1% (n = 11) are unsure. The following variables are related to attitude towards living kidney donation: (1) attitude towards cadaveric organ donation (P < 0.001); (2) having previous experience with the donation and transplantation process (P = 0.001); (3) participation in social help activities (P = 0.010); (4) having spoken about the matter within the family unit (P = 0.036); (5) the attitude of a respondent's partner towards the matter (P = 0.001); (6) knowing that one's own religion is in favour of this type of therapy (P = 0.002); (7) evaluation of the risks involved in this kind of donation (P < 0.001) and (8) concern about 'mutilation' after donation (P < 0.001). In the multivariate analysis, two variables are significantly related to this attitude: a negative attitude towards cadaveric donation (odds ratio = 0.309) and knowing that one's religion is in favour (OR = 1.745). CONCLUSIONS: The attitude of British and Irish citizens who are resident in southeastern Spain is very favourable and their attitude is very closely related to attitude towards cadaveric donation, family attitude and the attitude of their religion. The patients on the waiting list who are of British or Irish origin would be an ideal group to whom living kidney donation could be offered.  相似文献   

2.
INTRODUCTION: Most Spanish transplant centers have on-going living kidney transplant programs. However, such transplants are not increasing as a proportion of the total number of kidney transplants. The objective of this study is to analyze the attitude of kidney patients on the kidney transplant waiting list toward living kidney donation. MATERIALS AND METHODS: The patients studied were selected from those included on the kidney transplant waiting list from November 2003 until September 2005 (n = 221). Attitude toward living donation was evaluated using a psychosocial questionnaire. It was completed in a direct personal interview with an independent health-care worker from the Transplant Unit. Student's t-test and the chi-squared test were applied. RESULTS: Two hundred and fourteen patients completed the questionnaire (97%), of which 35% would accept a related living kidney if it were offered to them, 60% would prefer to wait on the waiting list and the remaining 5% are undecided. Up to 66% (n = 134) of patients report that a member of their family or a friend have offered them an organ for donation. Eighty-nine percentage believe that there is some risk involved in living kidney donation, although it is not a factor that affects whether an organ would be accepted or not (p = 0.767). The psychosocial variables that affect attitude toward accepting a related living kidney are: (i) age: the youngest are those who are most likely to accept (40 vs. 45-yr-old; p = 0.010); (ii) descendents: patients without descendents are more likely to accept a living organ (56% vs. 27%; p < 0.000); (iii) marital status: a greater percentage of single respondents would be prepared to receive this type of transplant compared to the group of married respondents (55% vs. 30%. p = 0.007); and (iv) level of education: those with a higher level of education are more likely to accept a living organ (43% have secondary or university studies vs. 28% who only have primary education; p = 0.040). CONCLUSION: Patients on the waiting list for a kidney transplant do not have a very favorable attitude toward receiving a related-living donor organ, although members of their family have offered them one of their organs. The profile of a patient who would accept a related-living donated kidney is a young, single person, without descendents, and with a high level of education.  相似文献   

3.
4.
Emigration from East European (EE) countries into the South East of Spain (SES) is becoming more common. The objective of this study was to analyse the attitude towards living kidney donation in this group. A sample of residents ( n  = 320) in the SES who come from EE was obtained randomly and stratified by a respondent's nationality (November-05 to April-06). Attitude was evaluated using a validated questionnaire that was completed anonymously and was self-administered. Control group: native Spanish citizens. The questionnaire completion rate was 83% ( n  = 265). A total of 83% ( n  = 220) were in favor of related living donation. Attitude is similar to that of the urban control group ( P  = 0.0534) and more positive than that prevalent in the rural setting ( P  < 0.001). The variables that were related to attitude included: a respondent's marital status ( P  < 0.001); the country of origin ( P  = 0.014); attitude towards deceased donation ( P  < 0.001); having discussed the subject within the family ( P  < 0.001); a respondent's belief that he might need a transplant organ ( P  = 0.002) and concern about possible 'mutilation' after donation ( P  < 0.001). There is a favorable attitude towards related living kidney donation among EE who are resident in the SES and this attitude is closely related to attitude towards deceased donation, the attitude of one's family and feelings of reciprocity.  相似文献   

5.
Abstract The demand for transplantation exceeds the availability of cadaveric organs, which is why the importance of living, related kidney transplantation is increasing. In our study we wanted to evaluate the experiences of living related donors (LRD). Between 1973 and 1996, 1325 kidney transplantations were performed at our Department. Of these 1247 were from cadaver donors while 78 were from LRD. We contacted each living donor by post. We carried out a physical examination, laboratory tests, ultrasound and isotope investigations and they were interviewed and completed a questionnaire. Thirty previous kidney donors came to our Department who were all blood relatives of the recipients. In the recipient group, 16 still have a functioning kidney, the average time since transplantation being 8.92 years. The longest kidney survival time is 18 years. All the donors willingly donated their kidney, none was worried about their own health and their only concern was whether the kidney would function or not. Regarding general attitudes towards living related organ transplantation, all were in favour of blood relative donor transplantation and also husband/wife transplantation. Opinions regarding non-related transplantation were more mixed; 63.3% would have given their kidneys to a friend, only 46.6% to a stranger. Almost two-thirds (63.3%) of donors were not in favour of selling and buying organs but, controversially, they would have bought an organ had one been available. All agreed that the donation did not change their general health. In conclusion, the donors of living, related kidney transplantation all agreed that it was a good thing to donate; All confirmed they would go through the same procedure again in order to help. Apart from one person, who emphasised that he is agnostic, all belonged to a Christian religion.  相似文献   

6.
目的了解医院住院患者对器官移植与捐献相关领域的认知情况和态度。方法通过自编调查问卷形式,以医院住院患者为对象进行问卷调查。内容包括一般信息、对器官移植与捐献的认知和态度,并分析影响器官移植和捐献、对移植和捐献关注的问题以及捐献方式的影响因素。数据结果以SPSS 18.0进行分析。结果本次调查共发放问卷1 000份,回收973份,有效问卷906份,有效率为93.1%。906份有效问卷中,788例(87.0%)患者听过器官移植,118例(13.0%)未听过器官移植;189例(20.9%)有移植亲属,717例(79.1%)无移植亲属;511例(56.4%)愿意接受器官移植,226例(24.9%)不愿意,169例(18.7%)不知道;490例(54.1%)同意器官捐献,173例(19.1%)不同意,243例(26.8%)不知道。性别因素对器官移植(P=0.299)和捐献(P=0.327)的意愿均无影响,年龄、学历、职业、是否听过器官移植及是否有移植亲属对器官移植和捐献的意愿均有影响(P<0.01)。性别因素对关于器官移植(P=0.727)和器官捐献(P=0.935)关注问题均无影响,年龄、学历、是否听过器官移植、是否有移植亲属对器官移植和捐献后关注的问题均有影响(P<0.01)。对器官移植手术最关注的问题依次为:是否有可供移植的器官占28.7%(260/906),术后生活质量占23.0%(208/906),手术风险占21.5%(195/906),手术费用占19.5%(177/906),术后排斥反应占7.3%(66/906)。器官捐献后最关注的问题依次为:捐献器官的合理应用占57.4%(520/906),亲属的态度占23.8%(216/906),捐献补偿占17.6%(159/906),其他占1.2%(11/906)。捐献方式上,403例(44.4%)愿意接受心脏死亡器官捐献(DCD),257例(28.4%)愿意接受脑死亡器官捐献,246例(27.2%)愿意接受活体器官捐献。性别、学历和职业对捐献方式有影响(P<0.05),而年龄、是否听过器官移植和是否有移植亲属对捐献方式无影响(P>0.05)。结论对器官移植宣传的不足和高昂的移植费用是制约器官移植接受率的主要因素,随着时间推移、全民教育水平的不断提高和加强对器官移植的广泛宣传,器官移植的接受率将呈现不断增高的趋势。目前医院患者普遍接受的器官捐献方式仍然是DCD。建立一个合理运作的捐献器官分配体系和适当的捐献补偿机制是促进器官捐献事业发展的关键。  相似文献   

7.
Anonymous nondirected living liver donation (ANLLD), sometimes referred to as “altruistic” donation, occurs when a biologically unrelated person comes forward to donate a portion of his/her liver to a transplant candidate who is unknown to the donor. Here, we explore the current status of ANLLD with special consideration of published reports; US experience; impact on donor psychosocial outcomes; barriers to donation; and current global trends with respect to ethical considerations. Between 1998 and 2019, 105 anonymous nondirected living liver donor (ND-LLD) transplants have been documented in the US Scientific Registry of Transplant Recipients. Sixteen donors (15%) were reported to experience a postoperative complication. Currently, 89 donors remain alive (85%), 16 (15%) have unknown status, and none are confirmed deceased. Although there are only a handful of case series, these data suggest that ANLLD is a feasible option. While there are no liver-specific data, studies involving anonymous nondirected kidney donors suggest that anonymous donation does not adversely impact psychosocial outcomes in donors or recipients. There are substantial financial burdens and ethical considerations related to ANLLD. Further studies are required to assess donor demographics, psychosocial motivations, long-term health-related quality of life, and financial impact of ANLLD.  相似文献   

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In Spain, despite its high rate of cadaveric donation, death while on the liver transplant waiting list is high. For this reason, living liver donation is being encouraged despite of the risk of morbidity for the donor. The objective of this study was to analyze attitudes toward living liver donation among hospital personnel in a hospital with a recently authorized living donor liver transplantation program. A random sample was taken and was stratified by type of service and job category (n = 1,262). Attitude was evaluated by means of a validated psychosocial questionnaire. The questionnaire was completed anonymously and was self-administered. Statistical analysis included the Student t test, the chi(2) test, and logistical regression analysis. The questionnaire completion rate was 93% (n = 1,168). Only 15% (n = 170) of respondents were in favor of living liver donation if it were unrelated. An additional 65% (n = 766) were in favor if this donation, but only for relatives. Of the rest, 9% (n = 107) did not agree with living liver donation, and the remaining 11% (n = 125) were undecided. The variables related to this attitude were age (P = 0.044); job category (P = 0.002); type of service (according to whether it is related to organ donation and transplantation) (P = 0.044); participation in prosocial activities (P = 0.026); attitude toward cadaveric organ donation (P <0.001); attitude of a respondent's partner toward organ donation (P = 0.010); a respondent's belief that in the future, he or she may need a transplant (P < 0.001); and a willingness to receive a donated living liver organ if one were needed (P < 0.001). There is also a close relationship between attitude toward living kidney donation and living liver donation (P < 0.001). In the multivariate analysis, the only common independent variable from the bivariate analysis was a willingness to receive a living donor liver transplant if one were needed (odds ratio = 9.3). Attitude toward living liver donation among hospital personnel in a hospital with a solid organ transplant program is favorable and is affected by factors related to cadaveric donation, altruistic activity, and feelings of reciprocity. Physicians and the youngest hospital workers are those who are most in favor, which leads us to think that there is a promising future for living liver transplantation, which is essential given the cadaveric organ deficit and the high mortality rate while on the waiting list.  相似文献   

10.
Development of live donor kidney transplantation (LDKT) programs has intensified debate regarding acceptability of certain donor categories and potential commercialization. Concerning these issues, we surveyed the views of medical and nursing staff caring for patients with renal failure and renal transplant recipients and donors. Participants were recruited from a tertiary transplant unit and invited to complete an anonymous questionnaire. Four hundred and sixty-four participants completed the questionnaire (42% response). One hundred and sixty-eight (36.2%) were health care professionals and 296 (63.8%) patients; 85.6% of participants were willing to donate to their children, 80.2% to siblings, 80.8% to parents, 72% to a non-blood-related relative or friend, and 15.3% to a stranger. If participants had hypothetical renal failure, they were prepared to accept a kidney from a parent (79.5%), sibling (78.7%), child (56.3%), a non-blood-related relative or friend (79.3%), or stranger (54.1%). Regarding commercialization, responders' attitudes were that the donor should not accept financial reward (29.1%), be compensated for expenses only (60.6%), or should receive a direct financial reward (10.1%). For non-directed donation, 23.5%, 55.6%, and 20.7% were not in support of reward, compensation only, and financial reward, respectively. While live kidney donation was accepted by the majority of individuals surveyed, only the minority approved of commercialization.  相似文献   

11.
Australian nephrologists' attitudes towards living kidney donation.   总被引:3,自引:0,他引:3  
BACKGROUND: The demand for deceased donor kidneys far outweighs the supply. The rate of living kidney donation (LKD) has been steadily increasing world-wide and is associated with excellent outcomes for the recipient. With respect to donors' outcomes, however, a strong evidence base is lacking. This study explores the attitudes and perceptions of Australian nephrologists towards LKD, specifically regarding donor risk, their willingness to recommend LKD and their own preparedness to become a live donor. METHODS: A postal survey of Australian nephrologists was conducted. Responses to six multiple choice questions about LKD were collected as a separate focus of a larger study. RESULTS: We achieved a survey response rate of 52.4% and analysed responses from 184 practicing nephrologists and trainees. Australian nephrologists and trainees were generally supportive of LKD. The vast majority (95%) of respondents indicated that they would recommend it to a suitable donor or would themselves (97%) donate a kidney to an immediate family member. However, fewer than half (43%) would recommend LKD to a potential donor, where their relative's end-stage kidney disease (ESKD) had been attributed to diabetes and where there was a strong family history of diabetes. A minority thought that LKD increased the donor's risk of mortality (12%) or of ESKD (25%). Few nephrologists (4%) indicated their preparedness to be an altruistic donor--to a recipient unknown to them. CONCLUSIONS: Although LKD is clearly supported by the nephrologists, the increasing incidence of ESKD attributable to diabetes, now the leading cause of ESKD in Australia, might, however, progressively limit its use. Meeting the growing demand for kidney transplantation will require an increased supply of both live and deceased donor kidneys. We should develop, evaluate and implement best-practice approaches to achieve this.  相似文献   

12.
The purpose of this study is to systematically review guidelines, position papers, and reports on living kidney donation by minors. We systematically searched the databases such as Medline, Embase, ISI Web of knowledge, Google scholar as well as the websites of various bioethics committees, transplant organizations and societies. Guidelines were included if they provided recommendations for or against living kidney donation by minors. Data were analyzed using qualitative content analysis. We included 39 documents in this study. Twenty seven of these endorse an absolute prohibition of living kidney donation by minors, because of concerns regarding the decision‐making capacity of minors, the impartiality of parental authorization, the best interests of the minor, and the necessity of the donation. Twelve guidelines, however, would exceptionally allow living kidney donation by minors, provided that adequate safeguards are put in place, including an assessment of the minor's autonomy and maturity, authorization by an independent body, assuring that the anticipated psychosocial benefits outweigh the medical and psychosocial risks for the donor and the restriction to situations of last resort. A more adequate medical and psychosocial follow‐up of living kidney donors may likely contribute to a more unified approach towards living kidney donation by minors.  相似文献   

13.
The effect of state legislation and federal policies supporting living donors on living kidney donation rates in the United States is unknown. We studied living kidney donation rates from 1988 to 2006, and we assessed changes in donation before and after the enactment of state legislation and the launch of federal initiatives supporting donors. During the study, 27 states enacted legislation. Among states enacting legislation, there was no statistically significant difference in the average rate of increase in overall living kidney donations after compared to before state legislation enactment (annual increase in donations per 1 000 000 population [95% confidence interval] 2.39 [1.94–2.84] compared to 1.68 [0.89–2.47] respectively, p > 0.05). Among states not enacting legislation, there was a statistically significantly greater annual increase in overall donation rates from 1997 to 2002 compared to before 1997 when federal initiatives commenced, but there was no growth in annual rates after 2002. State and federal legislation were associated with increases in living-unrelated donation. These findings suggest that although existing public policies were not associated with improvements in the majority of donations from living-related donors, they may have had a selective effect on barriers to living-unrelated kidney donation.  相似文献   

14.
The use of living donors for kidney transplantation in the United States is common, and long-term studies have demonstrated the safety of donation by young, healthy individuals. However, transplant programs have little data to guide them in deciding which donors are unacceptable, and which characteristics are associated with kidney disease or poor psychosocial outcomes after donation. To document current practices in evaluating potential donors, we surveyed all US kidney transplant programs. Compared to a survey 12 years ago, medical criteria for donation are more inclusive in several areas. All responding programs now accept living unrelated donors. Most programs no longer have an upper age limit to be eligible. Programs are now more likely to accept donors with treated hypertension, or a history of kidney stones, provided that certain additional criteria are met. In contrast, medical criteria for donation are more restrictive in other areas, such as younger donor age and low creatinine clearance. Overall, significant variability remains among transplant programs in the criteria used to evaluate donors. These findings highlight the need for more data on long-term outcomes in various types of donors with potential morbidities related to donation.  相似文献   

15.
INTRODUCTION: There has been an increase in the population resident in southeast Spain originating from the British Isles, among them Irish citizens. Living kidney donation rates are currently low in Spain. In an attempt to increase these rates, a search is underway to find groups who are favorable toward this type of donation especially from those countries with high levels of living kidney donation. The objective of this study was to analyze the attitudes toward living kidney donation among the population group originating from Ireland (including Northern Ireland) and who live in southeast Spain. MATERIALS AND METHODS: A random sample (n = 325) of the population in southeast Spain (Autonomous Community of Murcia) who were born in Ireland completed a validated questionnaire to measure attitudes. The questionnaire was self-administered and was completed anonymously between November 2005 and March 2006. Spanish citizens from an urban and a rural area were used as control groups (n = 500). RESULTS: The questionnaire completion rate was 81% (n = 262) including 87% (n = 229) of respondents in favor of living related donation and 13% (n = 94) against it. The attitude was similar to that of the urban Spanish control group (87% vs 89%; P = .5832) and more favorable than that of the rural area (87% vs 29%; P < 0.001). With respect to living donation for monetary incentives, 7% (n = 16) reported that they would donate an organ while alive for money, although this would depend on the quantity of money offered; 4% (n = 10) would need to think about it; while the vast majority (81%; n = 212) would never donate an organ in life for money. The following variables influenced attitudes toward living kidney donation: respondent sex (P = .023); previous experience with the donation and transplantation process (P = .004); participation in prosocial activities (P = .016); religion (P = .003); partner's attitude toward the matter (P = .020); concern about "mutilation" after donation (P < .001); and belief that living kidney donation is a risk for the patient (P = .003). CONCLUSION: Irish citizens living in southeast Spain showed a favorable attitude toward related living kidney donation. Therefore, they are a priority group to whom the option of living kidney donation should be offered when a kidney transplant is needed by an Irish person.  相似文献   

16.
INTRODUCTION: A living donor kidney is currently the most accepted kind of solid organ donation, given the low level of morbidity and mortality and the good results in the recipient. In Spain, its use is still scarce; even many health service workers are not in favor. Our objective was to analyze the attitudes toward living kidney donation in a surgical department. MATERIALS AND METHODS: A random sample was stratified according to surgical services and job category in a tertiary hospital with an solid organ transplant program. Attitudes toward living kidney donation were evaluated using a questionnaire on donation and transplantation, which evaluated various psychosocial variables. Student's t test and the Chi square test were used. RESULTS: Two hundred sixty-three respondents of mean age 40 +/- 10 years were analysed for attitudes toward living kidney donation. The level of acceptance was 87% (n = 229) versus 13% undecided or against the procedure (n = 34). No differences were observed according to job category. The variables that showed a relationship with the attitude were the partner's attitude toward donation (P = .049); the possible need for an organ oneself (P = .0001); and belief that medical errors occur (P = .001). The attitude toward cadaveric organ donation was not reflective of that toward living kidney donation (P = .241). CONCLUSIONS: A favorable attitude toward living kidney donation was high among hospital staff of the surgical department. Those for whom it was not favorable were influenced by personal factors such as partner's attitude and the possibility of needing a kidney in the future.  相似文献   

17.
Background: Living kidney donation (LKD) is becoming increasingly necessary as a treatment option for reducing the deficit in transplant organs. Hospital personnel in services related to donation and transplantation play a key role in promoting this kind of donation. Objective: To analyze the attitude toward LKD among hospital workers in services related to donation and transplantation in Spain and Latin America. Methods: Eight hospitals in the “International Collaborative Donor Project” were selected (Spain–Mexico–Cuba). A random sample was taken which was stratified according to the type of service and job category, in transplant-related services. Results: Of the 878 respondents, 90% were in favor of related LKD, and 28% were in favor if the LKD was not related. Attitude was more favorable among Latin Americans workers compared to the Spanish (p?=?0.014). Other factors associated to attitude included: age (p?=?0.004); an attitude in favor of deceased donation and living liver donation (p?p?Conclusions: The attitude toward related LKD was very favorable among hospital personnel in units related to the donation and transplantation process in Spain and Latin America, which means that they could contribute to its promotion particularly at the current time when living kidney donation needs to be expanded.  相似文献   

18.
China has the largest population of end-stage liver disease patients, but the acceptance of liver donation is really poor. Our objective was to analyze the attitudes toward living liver donation among hospital workers in a hospital with an authorized living donor liver transplant program in northeast China. A random sample stratified by department of service and job category (n = 800) evaluated attitudes using a modified psychosocial questionnaire, which was self-administered and completed anonymously. The factors were divided into subcategories of psychosocial variables, family variables, and attitudes toward other types of organ donation and willingness to accept an organ if needed. The results showed favorable attitudes toward living liver donation among hospital personnel. Family factors were closely related to this attitude as were altruistic activities and feelings of reciprocity.  相似文献   

19.
BACKGROUND: Health professionals are increasingly turning to living organ donation to augment cadaveric donation. Although living donation is currently performed with donors who are either genetically or emotionally related to the recipient, a 1997 British Columbia Transplant Society survey indicated that 32% of BC residents would be willing to donate a kidney, while alive, to a stranger (unpublished data). The goal of this study is to tap the public pulse about the living anonymous donor (LAD) by replicating and expanding the 1997 findings. METHODS: Five hundred BC residents completed a telephone survey including demographic information, questions about their organ donation behaviors and attitudes, and their willingness to donate a kidney, while alive, to particular individuals (child, spouse, parent, relative, friend, and stranger). To improve the methodological rigor of the 1997 study, an informed condition was added in the current study where participants learned about living donation before being asked about their willingness to donate. RESULTS: There were no differences among the 1997 results and the two conditions in the 2000 survey. Twenty-eight percent of participants in the uninformed condition and 29% of participants in the informed condition indicated that they would be willing to be LADs. LADs were more likely than self-reported non-donors to have registered as cadaveric donors and to endorse attitudes that were congruent with wanting to donate to a stranger. CONCLUSIONS: This study replicates the 1997 findings and increases confidence that a significant minority of British Columbians support living anonymous donation and that some would consider becoming LADs themselves.  相似文献   

20.
INTRODUCTION: Living liver donation is not exempt from risks to the donor, although it is currently ethically accepted. It is important to examine the level of acceptance among the different health levels toward this therapeutic option, in order to design promotion and awareness-raising activities. The objective herein was to analyze the attitudes and the factors that condition them among nursing personnel in Primary Care (PC) toward living liver donation. MATERIALS AND METHODS: This random survey was stratified by geographical location (6 health areas in our community) among PC nurses, obtaining a total of 139 nurses from 34 health centers. Attitudes toward living liver donation were evaluated using a questionnaire on donation which included different psychosocial variables. For the distribution of the questionnaire, the nursing coordinator of each centers was contacted to distribute questionnaires which were completed anonymously. The chi-square test and Student t test were applied. RESULTS: Attitudes toward living liver donation were favorable in 89% of those questioned (n = 124) if it is related donation; 3% (n = 4) were against donating a living hemiliver and 8% (n = 11) had doubts. It is important that up to 76% (n = 106) have cared for transplant patients or patients awaiting transplant, however, no relationship was observed with attitude to this type of donation (P = .489). Of all the analyzed variables, there was only a significant relationship between attitudes and concern about possible body mutilation (P < .0005), and partners attitudes toward this matter (P < .0005). It is noteworthy that no relationship was found with attitudes toward cadaveric donation (P = .062). CONCLUSION: Despite the risk of morbidity and mortality in the donor, the attitude of the PC nursing personnel toward living liver donation was favorable, especially if the donation is related.  相似文献   

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