国家食品药品监督管理局国家药品标准(修订)颁布件(批件号:ZGB2011-17-29)

速效救心丸 【处方】川芎 冰片     

国家食品药品监督管理局国家药品标准修订批件(批件号：XGB2009-001)

氨酚咖匹林片 本品含对乙酰氨基酚（C8H9NO2）和阿司匹林（C9H8O4）均为标示量的95．0％～105．0％;咖啡因（C8H10N4O2．H2O）为标示量的90．0％～110．0％。     

国家食品药品监督管理局国家药品标准(修订)颁布件(批件号:ZGB2011-44)

【处方】川芎153．8g 白芷76．9g 羌活76．9g 细辛38．5g 防风57．7g 荆芥153．8g 薄荷307．7g 甘草76．9g 【制法】以上八昧,川芎、白芷、羌活、细辛、防风、甘草加水煎煮两次,第一次1．5小时,第二次1小时,煎液滤过,滤液合并;薄荷、荆芥提取挥发油,挥发油备用,提油后的水溶液滤过,滤液与上述滤液合并,     

国家食品药品监督管理局国家药品标准(修订)颁布件(批件号:ZGB2011-45)

本品为五加科植物三七Panax notoginseng（Burk．）F．H．Chen的根茎经加工制成的三七总皂苷配制成的灭菌水溶液。     

国家食品药品监督管理局国家药品标准(修订)颁布件(批件号:ZGB2011-41)

【处方】地黄108g 山药27g 酒萸肉27g 茯苓78g 牡丹皮27g 泽泻27g 桂枝27g 附子（炙）4．5g 牛膝（去头）27g 盐车前子27g 【制法】以上十味,粉碎成细粉,过筛,混匀。每100g粉末加炼蜜110～130g制成大蜜丸或每100g粉末加炼蜜35～50g与适量的水泛丸,干燥,制成水蜜丸,即得。     

国家食品药品监督管理局国家药品标准(修订)颁布件(批件号:ZGB2011-46)

【处方】北柴胡1000g 【制法】取北柴胡1000g,切段,加水11000mL,70oC温浸8小时。经水蒸气蒸馏,收集初馏液6000mL,再重新蒸馏,收集重馏液约1000mL。加入聚山梨酯803g,搅拌使油完全溶解,再加入氯化钠9g,溶解后,滤过,加注射用水至1000mL,用10％氢氧化钠溶液调节pH值至7．0,精滤,灌封,灭菌,即得。     

国家食品药品监督管理局国家药品标准(修订)颁布件（批件号:ZGB2011-36-46）

【处方】丹参450g 三七141g 冰片8g 【制法】以上三味,三七粉碎成细粉,备用。冰片加乙醇适量使溶解,另取倍他环糊精40g,加水置55％恒温水浴中,搅拌使溶解,再边搅拌边滴加冰片的乙醇溶液,在不断搅拌下继续保温30分钟,取出,冷藏,抽滤,滤渣40℃烘干备用。丹参加乙醇加热回流1．5小时,提取液滤过,滤液回收乙醇并浓缩至适量,     

Occurrence and Exposure Assessment of Deoxynivalenol and Its Acetylated Derivatives from Grains and Grain Products in Zhejiang Province,China (2017–2020)

Deoxynivalenol (DON) together with its acetylated derivatives cause detrimental effects on human health, and the purpose of this study was to assess the prevalence of DON and its acetylated derivatives from grains and grain products in Zhejiang province, China, and to assess the risk of DON and its acetylated derivatives due to multiple consumptions of grains and grain products among the Zhejiang population. Food samples numbering 713 were collected, and the LC-MS/MS method was used to determine the toxins. The levels of toxins from grains and grain products were relatively low: DON was the toxin at the highest levels. The food frequency questionnaire was used to collect food consumption data. The result of exposure assessments showed that the population was overall at low levels of toxin exposure. The probable mean group daily intake of toxins was 0.21 μg/kg bw/day, which was far from the group provisional maximum tolerable daily intake of 1 μg/kg bw/day, but 0.71% of participants were at high exposure levels. Rice and dried noodles (wheat-based food) were the main sources of toxin exposure, and reducing the consumption of rice and dried noodles while consuming more of other foods with lower levels of toxins is recommended.