浅表脂肪瘤样痣1例

患者女,10岁。骶尾部丘疹、融合性斑块9年余。皮肤科情况:骶尾部可见簇集分布的米粒大淡黄色丘疹,质地柔软,融合成多处大小不等斑块或斑片,皮疹中央可见2处1.0cm×1.5cm大瘢痕增生。皮损组织病理示:表皮轻度角化过度,棘细胞层增生,真皮浅中层胶原束间可见成群分布异位脂肪细胞。诊断:浅表脂肪瘤样痣。     

Huge Nevus Lipomatosus Cutaneous Superficialis on Back: An Unusual Presentation

Nevus lipomatosus cutaneous superficialis (NLCS) is a benign dermatosis, histologically characterized by the presence of mature ectopic adipocytes in the dermis. We hereby report a case of a 10-year-old boy who presented with multiple huge swellings on the scapular regions and lower back. The lesions were surmounted by small papules, along with peau-d orange appearance at places. Histology showed features consistent with NLCS. The case is being reported for the unusual clinical presentation.     

Nevus Lipomatosus Cutaneous Superficialis. An Electron Microscopic Study of Four Cases

Four cases of nevus lipomatous cutaneous superficialis were studied under the electron microscope. The results showed the vascular origin of the fat cell and differentiation of young fat cells into mature fat cells. These findings are comparable to those observed in fetal adipogenesis.     

浅表性脂肪瘤样痣一例报告

浅表性脂肪瘤样痣(Naevus Lipomatodes Superficialis),此病临床较为少见,现将我院所遇一例报告如下.     

巨大浅表脂肪瘤样痣1例

患者女,22岁。出生后发即发现右侧胸部丘疹、结节等软性皮损,皮疹呈进行性增多,扩大至腋下。查体右侧胸部及腋下可见多个皮色或黄色的米粒至甲板大小扁平或半球形丘疹、结节、皮赘,触之柔软,部分皮疹融合成斑块。皮损组织病理示:真皮中上部胶原束间见脂肪细胞团块,呈片状或叶状分布,脂肪细胞形态成熟,发育正常。弹力纤维染色可见弹力纤维减少或短小、破碎。组织病理学诊断为浅表脂肪瘤样痣。腋下皮损行局部切除,疗效满意。     

Nevus Lipomatosus Cutaneus Superficialis (Hoffmann-Zurhelle)

We are reporting seven cases with nevus lipomatosus cutaneus superficialis. A review of the literature indicates that this is a relatively rare type of connective tissue nevus with little more than 50 cases recorded. Localization of the cutaneous nodular lesions over the upper thigh and buttock and histologic findings of fat lobules within the substance of the nevoid malformation differentiate these lesions from other varieties of the connective tissue nevi.     

表现为浅表脂肪瘤样痣的毛囊皮脂腺囊性错构瘤1例

患者女,36岁。颈部丘疹30余年。颈部可见密集呈片状分布的皮色圆顶丘疹,约绿豆大小,质韧。皮损组织病理示:角化过度,表皮大致正常,真皮内可见多数大的分化成熟的皮脂腺体,开口于毛囊漏斗部,腺体周围间质有裂隙,真皮内胶原增生致密。诊断:毛囊皮脂腺囊性错构瘤。     

膝部单发浅表性脂肪瘤样痣1例

患者男,29岁,左膝皮色结节逐渐长大5年余,无明显症状。皮肤镜检查示:类黄白色均质无结构区,边缘灶性分布的浅褐色指纹状色素沉着。皮损组织病理示:真皮胶原纤维束间可见成熟脂肪细胞,脂肪细胞无异型性。诊断:单发型浅表性脂肪瘤样痣。     

Giant Cutaneous Horn Arising in an Epidermal Nevus

Cutaneous horns, which rarely occur in children, can overlie a large array of pathologic lesions that range from benign to malignant. When a cutaneous horn is encountered, it is not the horn itself that is of relevance, it is the nature of the underlying disease that dictates overall prognosis and management. In this report we present a case of a cutaneous horn arising within a linear verrucous epidermal nevus and briefly review cutaneous horns, with an emphasis on their clinical implications and differential diagnosis.     

Localized Cutaneous Argyria Mimicking Blue Nevus after Wearing Earrings

Localized cutaneous argyria is a rare condition in which the skin changes into blue-grey spots due to the absorption of silver. The lesions need to be differentiated from other pigmentary disorders and require radiographic and histological examination for more accurate diagnosis. Scanning electron microscopy and energy dispersive x-ray spectroscopy can be a confirmatory tool in the evaluation of silver elements in biopsy tissue. This report shows the localized cutaneous argyria in earlobe of a 21-year-old woman who wears silver earrings for 10 years.     

Nevus Anemicus: A Distinctive Cutaneous Finding in Neurofibromatosis Type 1

Nevus anemicus (NA) is a cutaneous anomaly characterized by pale, well‐defined patches with limited vascularization after rubbing. They are largely known to be associated with neurofibromatosis 1 (NF1) and have received little attention in the literature until recently. We sought to characterize the prevalence and clinical features of patients with NA and NF1. We conducted an observational prospective study of 99 children with NF1 at the Hospital Niño Jesús, Madrid, Spain, from January 1, 2012, through July 31, 2013, and reviewed three other series of patients with NF1 and NA recently reported. The prevalence of NA in children with NF1 ranged from 8.8% to 51%, being much more prevalent at younger ages. Prospective studies yielded a higher prevalence than retrospective studies. NA was located most commonly on the trunk, particularly on the anterior chest wall, and was often multiple. Patients with segmental NF1 or isolated café au lait spots rarely had NA, and NA was absent in other genodermatoses. The collection of data was not homogeneous in all studies. NA has a high prevalence in individuals with NF1 patients but seems to be absent in connection with other genodermatoses, therefore its presence can assist in the diagnosis of suspected cases of NF1. The subtle clinical appearance of NA makes its detection difficult, and physicians involved in the care of children with NF1 must be aware of its possible presence and significance.     

Subungual Congenital Nevus with Recurrent Nevus Phenomenon

Melanonychia is uncommon. We report the first case of histopathologic recurrence of a completely excised subungual congenital nevus that presented as congenital melanonychia     

Nevus anemicus

The results of three cases of nevus anemicus studied by mechanical, histologic, pharmacologic, and electron microscopic technics are presented. The proposed pathogenesis and the differential diagnosis of this congenital disorder are discussed.     

Nevus spilus

Nevus spilus (NS), also known as speckled lentiginous nevus (SLN), is a relatively common cutaneous lesion that is characterized by multiple pigmented macules or papules within a pigmented patch. It may be congenital or acquired; however, its etiology remains unknown. NS deserves its own place in the spectrum of classification of important melanocytic nevi; as a lentigo and melanocytic nevus, it has the slight potential to develop into melanoma. Accordingly, we recommend consideration of punch excisions of the speckles alone if excision of the entire NS is declined.