射频消融髓核成形术改善腰椎间盘突出症患者症状效果评估

目的评估射频消融髓核成形术对腰椎间盘突出症患者术后1周,1年,2年的疗效。方法荆州市中心医院骨科2002-03/2004-08进行射频消融髓核成形术治疗腰椎间盘突出症患者56例。在术前、术后1周、术后1年及术后2年采用日本矫形外科学会下腰痛评分法进行评分,计算出该手术治疗后的改善率,同时进行主观满意度分级。结果术前平均下腰痛评分为(16.56±2.25),术后1周、1年及2年平均下腰痛评分为(26.38±1.77),(24.47±2.31),(21.33±2.55),平均改善率分别为(75.69±5.46)%,(60.79±5.81)%,(48.88±6.57)%,主观满意度优良率分别为83%(45/56),60%(19/32),50%(10/19)。结论射频消融髓核成形术后1周,1年,2年下腰痛评分逐渐降低,说明减轻患者的疼痛是肯定的,但平均改善率和主观满意度优良率逐渐降低,远期疗效还不能肯定,有待进一步证实。     

髓核减压结合脊神经后支射频热凝治疗盘源性下腰痛

目的:评价腰椎间盘髓核减压结合脊神经后支热凝治疗盘源性下腰痛的有效性。方法:80例明确诊断为盘源性下腰痛的患者随机分为两组,治疗组(A组,n=40)行髓核钳夹减压术结合脊神经后支射频热凝术。对照组(B组,n=40)单纯采用髓核减压术治疗;手术效果按照疼痛视觉类比评分(Visual Analogue Scale,VAS)和改良的MacNab标准评定,记录两组术中异常情况、不良反应及术后随访满意度。结果:所有病例均顺利完成手术。根据改良的MacNab标准评估后,A组的有效率达90.0%,明显高于对照组的80.0%,差异具有统计学意义(P<0.05)。治疗后3天和3个月后患者的VAS评分与治疗前相比,治疗组及对照组均明显降低,差异有显著性意义(P<0.05);而治疗组与对照组相比,VAS下降更明显,差异也有显著性意义(P<0.05)。结论:腰椎间盘髓核减压术结合脊神经后支射频热凝治疗盘源性下腰痛疗效更好,而且无明显不良反应发生。     

射频消融髓核成形术改善腰椎间盘突出症患者症状效果评估

目的评估射频消融髓核成形术对腰椎间盘突出症患者术后1周，1年，2年的疗效。方法荆州市中心医院骨科2002—03／2004—08进行射频消融髓核成形术治疗腰椎间盘突出症患者56例。在术前、术后1周、术后1年及术后2年采用日本矫形外科学会下腰痛评分法进行评分，计算出该手术治疗后的改善率，同时进行主观满意度分级。结果术前平均下腰痛评分为(16．56&;#177;2．25)，术后1周、1年及2年平均下腰痛评分为(26．38&;#177;1．77)，(24．47&;#177;2．31)，(21．33&;#177;2．55)，平均改善率分别为(75．69&;#177;5．46)％，(60．79&;#177;5．81)％，(48．88&;#177;6．57)％，主观满意度优良率分别为83％(45／56)，60％(19／32)，50％(10／19)。结论射频消融髓核成形术后1周，1年，2年下腰痛评分逐渐降低，说明减轻患者的疼痛是肯定的，但平均改善率和主观满意度优良率逐渐降低，远期疗效还不能肯定，有待进一步证实。     

低温等离子射频消融髓核成形术治疗颈性眩晕的疗效

目的观察低温等离子射频消融髓核成形术治疗颈性眩晕的临床疗效。方法 37例颈性眩晕患者(共87个颈椎间盘)进行低温等离子射频消融髓核成形术。分析患者术前和术后VAS分值的变化,评价患者临床疗效。结果 37例患者术前VAS分值为(6.76±0.52),术后1年VAS分值为(2.95±0.63),差异有统计学意义(P0.01)。术后1年有效率为86.5%。结论低温等离子射频消融髓核成形治疗颈性眩晕安全、有效。     

经皮射频消融术治疗21例神经根型颈椎病的临床疗效观察

选择2009年5月~2011年1月我院收治的神经根型颈椎病患者共有21例,采用经皮射频消融髓核成形术进行治疗,对患者术前、术后14d以及末次随访的VAS评分、NDI评分以及颈椎稳定性进行比较观察。结果患者术后14d、末次随访的VAS评分显著低于术前评分(P0.05);患者术后14d、末次随访的NDI评分显著低于术前评分(P0.05);经过12~24个月随访,未发现患者手术阶段不稳定以及椎间隙塌陷。经皮射频消融髓核成形术能够有效治疗神经根型颈椎病,值得临床运用。     

Disc-FX系统经皮椎间盘切除、射频消融术治疗椎间盘源性腰痛的临床研究

目的:观察Disc-FX系统经皮椎间盘摘除、射频消融术治疗椎间盘源性腰痛的近期疗效.方法:选择自2010年7月至2010年10月在我院应用Disc-FX系统经皮髓核摘除、射频消融术治疗椎间盘源性腰痛并且随访资料完整的患者36例,比较术前、术后即刻、l周、3月、6月JOA、VAS及Oswestry(2.0版本)评分.结果:36例患者术后JOA评分较术前明显升高,术后VAS和Oswestry评分较术前明显降低,有统计学意义(P＜0.01).结论:Disc-FX系统经皮椎间盘切除、射频消融术是治疗椎间盘源性腰痛的有效方法.     

经皮射频消融髓核成形术治疗椎间盘源性腰痛的围手术期护理

目的 探讨椎间盘源性腰痛经皮射频消融髓核成形术患者的围手术期护理.方法 对行经皮射频消融髓核成形术治疗的154例患者进行术前镇痛及手术安心工程、术中适时沟通、术后及时的功能锻炼.结果 154例患者中70例术后腰痛即刻消失；4例术后1d腰痛加重,2d后缓解；3例先后接受2次同一间隙消融,腰痛部分缓解；2例无效,术后保守治疗3～5个月后患者腰痛加重,行髓核摘除加椎间融合术.结论 经皮射频消融髓核成形术治疗椎间盘源性腰痛的临床疗效优良,精心护理是保证手术成功的关键.     

等离子髓核成形术在颈椎盘源性疼痛中的应用评价

目的:评价等离子髓核成形术在颈椎间盘源性疼痛中的临床疗效.方法:自2009年3月至2010年12月,我院对152例伴颈肩部剧烈疼痛的颈椎间盘突出症患者371个椎间盘进行了等离子髓核成形术治疗,疗效采用症状缓解率(VAS评分)和主观满意度优良率进行评估.结果:所有患者均获平均(13±5.7)个月的随访.VAS评分术前、术后1周及12个月分别为(8.3±1.1)分、(1.5±1.5)分和(1.9±1.7)分;术后1周及12个月症状缓解率分别为81.9%和77.1%.主观满意度优良率分别为93.4%和92.1%.经t检验,术后1周及12个月VAS评分均较术前明显降低(P<0.05).结论:经皮等离子髓核成形术能有效地缓解颈椎间盘突出症患者的疼痛症状,具有操作简便、安全、起效快、疗效稳定、患者易于接受等优点,对保守治疗无效的顽固性颈椎间盘源性疼痛是一个良好的选择.     

等离子髓核成形术治疗腰椎间盘源性疼痛远期疗效的分析

目的 探讨髓核成形术治疗腰椎间盘源性疼痛的5年随访疗效.方法 对获得5年以上随访的41例诊断为腰椎间盘源性疼痛患者使用等离子髓核成形术后进行疗效分析,采用患者主观满意度、视觉疼痛模拟评分(VAS)及Oswestry功能障碍指数(ODI)评分,对患者腰腿疼缓解和日常生活状况进行疗效评估.结果 所有患者手术顺利实施,术后1例患者发生椎间盘炎,末次随访患者主观满意度为63.4%;术前、术后1周、术后3年、术后5年VAS评分分别为(7.9±0.7)分、(3.4±0.5)分、(2.9±0.4)分、(2.5±0.4)分;术前、术后1周、术后3年、术后5年ODI评分分别为(58.9±6.1)分、(42.1±4.2)分、(25.4±4.0)分、(23.0±2.9)分;术前、术后1周、术后3年的VAS及ODI评分有统计学差异(P<0.05),术后3年、术后5年的VAS及ODI评分不具有统计学差异(P>0.05).椎间隙、椎间盘退变MRI分级、椎间盘造影诱发试验的分类均有统计学差异(P<0.05).结论 在长达5年的随访研究中,等离子髓核成形术对椎间盘源性疼痛患者获得较为满意的临床疗效,但仍需大样本的随机对照试验.     

经皮椎间孔镜下腰椎间盘切除术治疗下腰痛

目的探讨经皮椎间孔镜下腰椎间盘切除术(PELD)治疗下腰痛的可行性和有效性。方法回顾性总结2008年11月～2009年12月采用PELD治疗下腰痛患者79例,其中普通腰椎间盘突出症67例(合并轻度椎间孔狭窄44例),极外侧型腰椎间盘突出症6例,盘源性腰痛6例,所有椎间盘突出的均为包容型。于术前、术后1周及末次随访时进行视觉模拟疼痛评分(VAS),末次随访时按改良Macnab标准及患者满意度评价临床疗效。结果手术时间30～100 min,平均50 min;术后住院时间2～30 d,平均5.6 d。无手术并发症及转为其他手术方式。随访12～25个月,平均19.3个月。术前、术后1周及末次随访残余疼痛评分(VAS)分别是(8.75±0.25)、(4.12±0.51)、(3.86±0.43)分(P<0.05),1例患者末次随访时疼痛较术前加重。改良Macnab标准评价优良率70.9%,患者满意率63.3%。结论 PELD治疗下腰痛安全且近期效果良好,恰当的病例选择非常重要。     

椎间盘造影结合亚甲蓝注射治疗椎间盘源性下腰痛的初步疗效观察

目的:收集行椎间盘造影结合椎间盘内亚甲蓝注射治疗的椎间盘源性腰痛患者的术后及1年后随访资料进行分析,评估该技术的临床治疗效果.方法:2005年8月～2008年11月,我们对67例诊断为椎间盘源性腰痛并经过正规保守治疗3个月无效的患者,采用椎间盘造影结合椎间盘内亚甲蓝注射治疗治疗.通过对患者术后第2天与1年后视觉疼痛评分比例尺和SF-36躯体疼痛调查问卷评分分析,评价椎问盘内亚甲蓝注射治疗对椎间盘源性腰痛的治疗效果.结果:所有67例患者中,术后2天VAS得分较术前平均降低了4.33,SF-36问卷评分平均上升了20.11;术后获得1年随访的47例患者中VAS得分较术前平均降低了4.16,SF-36问卷评分平均上升了17.55.术后2天内及术后1年VAS得分和SF-36问卷评分与术前相比存在显著性差异(P＜0.001).治疗及随访期间未发生任何并发症.结论:椎间盘造影结合椎间盘内亚甲蓝注射治疗椎间盘源性腰痛近期疗效比较理想,是一种安全有效的治疗方法.     

经皮椎间孔镜下射频热凝纤维环成形联合髓核摘除修复腰椎间盘突出症

背景：侧后路经椎间孔镜下椎间盘髓核摘除联合射频热凝纤维环成形术是治疗慢性椎间盘源性腰腿痛的微创治疗方法,尤其适合于极外侧型椎间盘突出。目的：探讨经皮椎间孔镜下髓核摘除联合射频热凝纤维环成形术治疗腰椎间盘突出症的安全性及近期疗效。方法：32例腰椎间盘突出症患者者,均应用侧后路经皮椎间孔镜髓核摘除联合射频热凝纤维环成形术治疗,治疗前后采用目测类比评分和改良Macnab标准评价患者腰痛缓解情况,ODI评分评价患者的日常生活情况,随访时间1-6个月,平均3.5个月。结果与结论：所有患者均顺利完成治疗,无神经血管系统损伤等并发症发生。患者腰痛及生活能力均获得明显的改善。与治疗前相比,治疗后患者目测类比评分评分及ODI评分明显改善（P 〈0.01）;参照Macnnab疗效评定标准,结果显示治疗后1周有效率达到94%,治疗后3月有效率为97%。说明经皮椎间孔镜下髓核摘除联合射频热凝纤维环成形术治疗腰椎间盘突出症近期疗效肯定,并发症少,近期功能恢复稳定。     

A randomized controlled trial of radiofrequency denervation of the ramus communicans nerve for chronic discogenic low back pain

OBJECTIVE: The objective of this study was to determine the efficacy of percutaneous radiofrequency (RF) thermocoagulation of the ramus communicans nerve in patients suffering from chronic discogenic low back pain. METHODS: Forty-nine patients who suffered chronic discogenic low back pain at only 1 painful vertebral level, and whose pain continued after undergoing intradiscal electrothermal annuloplasty (IDET), were randomly assigned to 1 of 2 treatment groups. The lesion group (n = 26) received RF thermocoagulation of the ramus communicans nerve. Patients in the control group (n = 23) received an injection of lidocaine without radiofrequency. Visual analog scale (VAS) pain scores, analgesic requirements, SF-36 subscales, and the overall patient satisfaction with the procedure were tabulated. RESULTS: The average follow-up period was 4 months. The patient-reported VAS pain scores were significantly lower (P < 0.05) in the lesion group. The scores of the RF lesion group improved by a mean increase of 11.3 points (P < 0.05) on the SF-36 bodily pain subscale, and by a mean increase of 12.4 points on the physical function subscale (P < 0.05). In a follow-up analysis within the RF lesion group, VAS pain scores improved by a mean reduction of 3.32 (P = 0.001). The scores improved by a mean increase of 14.5 points (P = 0.005) on the SF-36 bodily pain subscale and 15.2 points(P = 0.002) on the physical function subscale within the RF lesion group. One patient in the lesion group complained of mild lower limb weakness, but he completely recovered at postoperative 15 days without any serious problems. DISCUSSION: In patients with chronic discogenic low back pain, percutaneous RF denervation of the ramus communicans nerve should be considered as a treatment option.     

Intradiscal pulsed radiofrequency application following provocative discography for the management of degenerative disc disease and concordant pain: a pilot study

Abstract: The development of diagnostic criteria and the use of provocative discography allow identifying the degenerative disc as causative structure for chronic low‐back pain. Unfortunately, none of the available interventional treatment options have been demonstrated to be effective over a prolonged period of time for a considerable number of patients. Pathophysiological studies indicate sprouting of sensory nerves and inflammatory processes as underlying pain mechanisms. Pulsed radiofrequency (PRF) treatment in small and larger joints was described to reduce pain and improve healing by stimulating the immunology. Earlier findings of PRF applied in the disc annulus were promising. It is assumed that PRF applied in the nucleus would change the conductivity of nerve endings and provide a clinically relevant pain reduction. The application of the electric field of PRF in the disc may also activate the immune system, thus reducing the inflammation process of chronic pain. Pulsed radiofrequency in the nucleus was studied in 76 patients with discogenic pain confirmed by magnetic resonance imaging and provocative discography. At 3‐month follow‐up, 38% of the patients had > 50% pain reduction, at 12 month the effect is maintained in 29%. In patients with unsatisfactory pain relief 3 months after the intervention, secondary pain sources may have been revealed. The latter were treated accordingly. Of all patients, 56% had > 50% pain reduction 1 year after first treatment. Our findings suggest that PRF in the nucleus may be considered for patients with proven discogenic pain. A randomized controlled trial to confirm our findings is justified.?     

CT引导下盘内外臭氧治疗椎间盘源性腰痛50例临床分析

目的探讨CT引导下臭氧治疗椎间盘源性腰痛的疗效。方法选取符合椎间盘源性腰痛标准50例患者,在CT引导下对58个椎间盘进行穿刺,在盘内及椎间孔区分别注射浓度为50μg/mL及35μg/mL的臭氧,根据视觉模拟评分及改良的Macnab疗效评定标准进行评定,观察疗效。结果 CT引导下均一次穿刺成功,58个间盘注射臭氧后均诱发或复制出下腰部疼痛,CT表现为纤维环部分撕裂18例,完全撕裂40例,术前及术后3d、3个月、6个月的视觉模拟评分分别为7.53±1.51、4.10±0.43、1.96±0.43、1.71±0.53,术前与术后各个时间段对比,差异具有统计学意义（P〈0.05）;术后3d、3个月、6个月的优良率分别为79.8%、89.7%、91.2%。结论 CT引导下盘内外注射臭氧治疗椎间盘源性腰痛操作简单,安全准确,不仅具有影像学诊断价值,而且疗效良好。     

持续硬膜外输注镇痛结合交感神经射频热凝治疗四肢带状疱疹后遗神经痛的疗效

摘要 目的：观察CT 引导下四肢带状疱疹后遗神经痛（PHN）持续硬膜外输注镇痛结合交感神经射频热凝治疗的临床结果。 方法：32例四肢带状疱疹后遗神经痛患者随机分为对照组（A组,采用硬膜外置管持续输注镇痛治疗,n=17）和联合治疗组（B组,采用持续硬膜外置管镇痛3—4周后行交感神经射频热凝治疗3次,n=15）,比较治疗前后7d、1个月、6个月、1年的视觉模拟评分（VAS）、疼痛缓解率、生存质量评分（QOL）、麻木评分、肌力下降发生率。 结果：治疗后两组患者的VAS评分均较治疗前明显降低（P<0.05）;治疗后6个月、1年,B组的VAS、QOL、疼痛缓解率均优于A组（P<0.05）,同时A、B两组的麻木发生率和麻木评分均无显著性差异（P>0.05）,治疗后两组均无肌力下降发生。 结论：四肢带状疱疹后遗神经痛持续硬膜外镇痛结合交感神经射频毁损治疗可有效缓解疼痛,长期疗效高于单纯持续硬膜外镇痛,同时并不增加麻木及肌力下降的发生率。     

The Swedish back school in chronic low back pain. Part I. Benefits

The aim of this 12-month follow-up study was to evaluate the effect of the Swedish-type back school in chronic low back pain. 188 subjects completed the study (95 in the treatment group and 93 in the control group). The following were assessed: 1) subjective scores of pain and disability; 2) clinical measurement and evaluation including spinal mobility and strength measurement; 3) number and length of sick-leaves. At 12 months, subjective scores of pain and disability, and mobility of the lumbosacral section of the spine showed differences in the favour of the treatment group. There was no difference, however, in the number or the length of sick-leaves after the back school. It was concluded that patients with chronic or recurrent low back pain may get relief of subjective symptoms of low back pain from the back school. In addition to chronicity, there may be other factors affecting the outcome of treatment.     

单纯后纵韧带增生型颈椎病责任间盘的确认及其射频治疗

目的:观察单纯后纵韧带增生型颈椎病的微创治疗效果。方法:具有颈、肩和上背部至少一处持续6个月以上酸、胀、麻、重或痛的患者30例,采用射频温度递增诱发试验代替椎间盘造影试验确定责任间盘及相对应的责任增生后纵韧带,采用射频热凝方式治疗单纯后纵韧带增生型颈椎病。结果:30例患者围术期及术后180天内未出现局部感染和颈脊神经损伤等并发症。术后72小时有14例颈、肩、上背部等部位原有症状全部消失,感觉轻松;13例原有症状明显减轻,感觉也比较轻松;3例原有症状部分消失或减轻另部分没有减轻。疗效优良率达到90%。术后72 h和术后180天的视觉模拟评分(visual analogue scale,VAS)较术前均有明显降低。结论:成对管状电极射频椎间盘成形术可用于单纯后纵韧带增生型颈椎病的治疗。     

Clinical predictors of success and failure for lumbar facet radiofrequency denervation

OBJECTIVE: To determine the clinical factors associated with the success and failure of radiofrequency denervation of the lumbar facet joints. METHODS: Clinical data were garnered from 3 academic medical centers on 192 patients with low back pain who underwent radiofrequency denervation after a positive response to diagnostic blocks. Success was defined as >/=50% pain relief lasting at least 6 months. Factors evaluated for their association with outcome included duration of pain, opioid use, symptom location, paraspinal tenderness, pain exacerbated by extension/rotation (ie, facet loading), MRI abnormalities, diabetes, smoking, scoliosis, obesity, prior surgery and levels treated. RESULTS: The only factor associated with a successful outcome was paraspinal tenderness. Variables that correlated with treatment failure were 'facet loading,' long duration of pain, and previous back surgery. CONCLUSIONS: It is counterproductive to use 'facet loading' as the sole basis for choosing patients for facet interventions. In patients at high risk for treatment failure, taking additional steps to reduce the rate of false-positive screening blocks may improve outcomes.