Paraganglioma of the nasal cavity: a case report

We describe the case of a 72-year-old woman presenting with a 1-year history of recurrent epistaxis and unilateral progressive nasal obstruction with associated rhinolalia resulting from the presence of a tumor mass occupying two-thirds of the right nasal cavity. Histopathologically, neoplastic cells or "chief cells" were arranged in well-defined nests, which had the classic alveolar or so-called "zellballen" pattern. Immunohistochemical studies highlighted the presence of S-100 protein-positive sustentacular cells located at the periphery of the clusters of chief cells. The chief cells showed a diffuse and intense positivity for neuron-specific enolase and synaptophysin. A diagnosis of paraganglioma was made. The lesion was excised completely and the patient did not develop recurrences or distant metastases after 8 months of follow-up. Paragangliomas arising in the nasal cavity and paranasal sinuses are extremely rare tumors. We report on the clinical, histopathological and immunohistochemical findings of our case and review the cases previously described in the literature.     

Leishmaniasis of the nasal cavity: a case report

Establishing diagnosis of a granulomatous lesion of the nose is often difficult. Here we report a case of granulomatous lesion of the nose caused by Leishmania--an unlikely cause in the UK. The diagnosis and management of the case is discussed here.     

Verrucous carcinoma of the nasal cavity: a case report

We report a rare case of verrucous carcinoma occurring in the nasal cavity. A 53-year-old man reporting left-sided nasal obstruction and awareness of a left intranasal lesion--a whitish polypoid lesion--was found in CT to have an expansive lesion of the left nasal cavity and maxillary sinus. The tumor was completely removed by Denker's operation. Verrucous carcinoma is a rare variant of squamous cell carcinoma most commonly seen in the oral cavity. In some cases, conventional squamous cell carcinoma components may be observed focally in verrucous carcinoma, called a hybrid tumor. In our case, the tumor showed typical features of a hybrid tumor. To the best of our knowledge, this is the first case of hybrid verrucous squamous cell carcinoma originating in the nose in the Japanese literature.     

Nodular fasciitis of the nasal cavity: a case report

Nodular fasciitis is an uncommon tumor-like fibroblastic proliferation of the head and neck that is difficult to differentiate from its more malignant counterparts. Despite modern advances, making this distinction is challenging because the clinical presentation is nonspecific and the histologic and radiologic features are variable. Once nodular fasciitis is diagnosed, the primary treatment is conservative resection and observation. We describe a case of nodular fasciitis of the nasal cavity in a 43-year-old woman. To the best of our knowledge, this is only the second reported case of nodular fasciitis arising in the nasal cavity, and the first such case in an adult.     

Complex odontoma of the nasal cavity: a case report

We describe the case of a 76-year-old man who presented with symptoms of chronic nasal obstruction and recurrent sinusitis of many years' duration. The patient's history and radiographic findings established a diagnosis of a complex odontoma of the nasal cavity. The mass was surgically excised, and the diagnosis was confirmed by histopathology. The occurrence of an odontoma in the nasal cavity is extremely rare.     

Extramedullary plasmocytoma of the larynx

Extramedullary plasmacytomata (EMP) are rare malignant neoplasms composed of plasma cells, 90 percent of which occur in the neck and head area, but generally representing only 1 percent of tumors of that location. The paper report a case of extramedullary plasmacytoma of the larynx, in a 62-year-old man. We also review the different malignant plasma cell dyscrasias, paying special attention to the EMP, given its predilection for the upper aerodigestive tract.     

Adenoid cystic carcinoma of the nasal cavity: a case report

Adenoid cystic carcinoma (ACC) is the most common malignant tumor of the minor salivary glands. The sinonasal tract is a common site of ACC occurrence, second only to the oral cavity. Of all cases of sinonasal ACC, a minority (22 to 35%) arise in the nasal cavity. Three histologic patterns of ACC have been described: cribriform, tubular, and solid. Compared with the cribriform and tubular forms, predominantly solid-type ACCs have been associated with higher rates of perineural invasion, higher S-phase fractions, and a higher incidence of aneuploidy. The histologic differentiation of solid-pattern ACC from other sinonasal malignancies typically requires the identification of one or both of the other ACC patterns in the same specimen. We present the case of a 39-year-old man with solid-pattern ACC arising in the nasal cavity. The tumor was resected endoscopically. We also discuss the relevant literature regarding the histologic diagnosis, prognosis, and treatment options for solid-pattern ACC.     

Hemangiopericytoma like tumor of the nasal cavity: a case report

Sinonasal hemangiopericytoma originates from vascular pericytes. It may arise in any part of the body but it is an uncommon vascular tumor in the nose. It can show benign or malignant histologic features. Sinonasal hemangiopericytoma like tumor is important as it is recognized as a special variant of hemangiopericytoma. In this article, we present a 65-year-old male patient with hemangiopericytoma like tumor of the nasal cavity.     

Malignant oncocytoma of the nasal cavity: a case report.

Malignant oncocytoma is a rare clinical entity and is most commonly seen in the salivary glands. Its occurrence in the nasal cavity is extremely rare, and only 4 such cases have been reported in the literature. The authors report one such case in a 60-year-old woman, which presented as a slow-growing nasal mass arising from the nasal septum, with no lymph node metastasis, which was successfully managed by a combined modality of treatment-surgery followed by radiation therapy. The relevant literature has been reviewed. The case is discussed as a possible differential diagnosis for a mass in the nose.     

鼻腔尤文肉瘤一例

患者女,40岁.因右侧鼻塞伴右眼流泪2个月于2006年9月8日入院.无涕中带血、视力模糊、头痛、面部麻木、牙齿疼痛及嗅觉减退症状.体检:鼻外形无明显畸形,鼻中隔稍偏左,右侧鼻腔总鼻道及下鼻道充满红色新生物,中鼻道少量黏性分泌物,左侧下鼻甲、中鼻道未见明显异常.鼻窦CT示右侧鼻腔可见大小约2.8 cm×2.5 cm的肿块,右侧下鼻甲及卜颌窦内侧壁骨质部分吸收(图1).     

鼻腔原发性粒细胞肉瘤一例

患者女,57岁,2007年4月因双侧鼻塞反复发作1年余入院.查体:鼻中隔左偏,双侧下鼻甲充血、肿胀,双侧中鼻道未见息肉样物及分泌物.行鼻窦CT检查示:左侧上颌窦、双侧筛窦炎症,双侧下鼻道见软组织密度影,阻塞右侧后鼻孔(图1a).入院诊断:"慢性鼻-鼻窦炎(Ⅰ型2期)、慢性肥厚性鼻炎".     

鼻腔多形性腺瘤恶性变一例

患者男，69岁。以右侧鼻塞5年，鼻旁隆起及鼻外肿块7个月于2006年2月23日入院。患者5年前因右侧鼻塞就诊于当地医院，表面麻醉下经前鼻孔行鼻腔肿物摘除，病理报告为鼻腔混合瘤。术后鼻腔通气较好，未曾复诊。半年前开始出现渐进性鼻塞及少量涕中带血，右侧鼻前孔有肿物突出伴右侧鼻背隆起畸形。4个月前在当地医院CT检查示右鼻腔前部有光滑肿物，骨质完整，未行治疗。近1个月来，     

Extramedullary plasmacytoma of the nasal cavity: treatment perspective in a developing nation

Extramedullary plasmacytomas are uncommon tumors, with a worldwide annual incidence of 3 per 100,000 population. They account for 1% of all tumors of the head and neck and 4% of all nonepithelial tumors of the nasal tract. A variety of treatment options has been suggested. These treatments vary according to the site of presentation, the presence of locoregional spread, and the histologic picture. Radiotherapy has been widely used as a treatment modality, but little has been written about surgery as a single management modality. However, such an option assumes importance in a developing nation, where patient follow-up is erratic and treatment costs must be kept low. We discuss the feasibility of surgery in such a circumstance, and we describe our surgical treatment of a case of extramedullary plasmacytoma in an elderly woman who presented to our hospital in India.     

Giant cell tumor of the nasal cavity: case report

Soft tissue giant cell tumor of low malignant potential is a rare tumor located in superficial and deep soft tissue. Tumors with osteoclast-like giant cells have been reported in various sites as breast, salivary glands, lung, kidney and pancreas. These tumors are composed of evenly spaced multinucleated giant cells in a background of mononuclear component composed of round, oval or spindled cells. No atypia or significant mitotic activity is encountered. Immunohistochemical stains for TRAP, smooth muscle actin, desmin and cytokeratins are of great value for diagnosis. Nasal cavity represents a very unusual location for this type of tumors; soft tissue tumors must be included in the differential diagnosis of nasal obstruction. Due to the possibility of local recurrence, clinical follow-up is recommended.     

鼻腔上皮样血管内皮瘤一例

患者女,48岁,因右侧鼻腔反复出血伴鼻塞3个月于2015年1月入院。患者入院前3个月无明显诱因出现反复右侧鼻腔出血,伴右侧鼻塞,嗅觉稍减退,无鼻痒、打喷嚏、流清涕。患者既往体健。查体：神志清楚,自主体位,查体合作,心肺腹未见明显异常。专科检查见右侧鼻腔一肿物堵塞右侧中鼻道、总鼻道,呈暗红色,质软,表面凹凸不平,