An investigation of the acute behavioural effects of styrene on factory workers

A group of men exposed to styrene in a factory building glass-fibre boats performed a series of behavioural tests at the beginning and end of their shift, and the results were compared with those of a referent group from the same factory. Changes in mood were noted in both groups of workers but were greater in the exposed men; moreover, the change in mood was correlated with blood styrene concentration. In the styrene workers the morning reaction time was slower than that for the referents. During the day the reaction time of the men with low blood styrene concentration (less than or equal to 5.4 mumol/l) speeded up and in the afternoon was similar to that of the referents; the reaction time for the men with high blood styrene concentration (greater than or equal to 5.5 mumol/l) was unchanged. Data taken from a questionnaire indicated that the men exposed were much more likely than was the referent group to report feeling unduly tired. They also reported feeling more tired on Friday night than Monday night, suggesting that the styrene might have a cumulative effect through the week.     

Neuroendocrine effects of styrene on occupationally exposed workers

The serum levels of prolactin (PRL), human growth hormone (HGH), thyroid-stimulating hormone (TSH), and the gonadotropins follicle-stimulating hormone (FSH) and luteinizing hormone (LH) were measured in 30 females exposed to about 130 (range 65-300) ppm of styrene in the air and in 30 age-matched referents to show whether styrene exposure influences the dopaminergic tuberoinfundibular system (TIDA). The exposed subjects' serum levels of PRL were more than double the reference values and were significantly related to the urinary excretion of styrene metabolites, ie, to the sum of mandelic acid (MA) and phenylglyoxylic acid (PGA) in the "next-morning" urine spot sample. Such a relationship still proved to be statistically significant after the removal of the effects of age and duration of exposure with the method of partial correlation. The serum concentrations of HGH in the exposed workers were also higher than in the reference group. Though within the reference levels, the TSH values of the exposed subjects were significantly related to the urinary excretion of MA and PGA. These results are consistent with the dose-dependent depletion in tuberoinfundibular dopamine after experimental styrene exposure of rabbits.     

An investigation into the acute vascular effects of riveting.

Measurements were made on 46 pairs of riveters and matched control subjects before and after a morning's work. Before starting work, the mean resting finger systolic pressure was 112 (SEM 3.3) mm Hg in the riveters, similar to 117 (1.7) in the control subjects. After cooling the middle phalanx to 10 degrees C for five minutes, 16 riveters but only one control subject exhibited digital vasospasm and these numbers were unaltered after a morning's work. A subgroup of riveters whose role was always to provide counter pressure to the rivet gun showed a higher incidence (45%) of cold induced vasospasm than did riveters who invariably held the gun (10%) or rotated between both roles (27%). Plasma levels of three markers of vascular activity, endothelin-1 (ET-1), von Willebrand factor antigen (vWFAg), and angiotensin converting enzyme (ACE), were measured in non-smoking riveters and control subjects. Before work, ET-1 concentrations were slightly lower (p < 0.05) in the riveters, but vWFAg concentration and ACE activity were similar in riveters and control subjects. Riveting for a morning did not alter ET-1 concentration or ACE activity but did induce a small increase (p < 0.05) in vWFAg concentration, which may indicate damage to the endothelium. This type of vascular assessment may be helpful in assessing vasospastic complications in workers exposed to vibration.     

No acute behavioural effects of exposure to styrene: a safe level of exposure?

To determine whether exposure to low levels of styrene (below 110 mg/m3) causes acute behavioural effects and symptoms that may be related to concentrations of styrene in air or urinary mandelic acid or both, 12 men occupationally exposed to styrene were studied and compared with a reference group of 10 unexposed men. Simple reaction time was measured before and after work and information about symptoms was obtained by questionnaire. Active and passive sampling of airborne styrene was carried out and urinary mandelic acid concentrations were measured. Although the size of the study groups is small, the results indicate that exposure to styrene below 110 mg/m3 does not cause any acute adverse effects on the central nervous system.     

No acute behavioural effects of exposure to styrene: a safe level of exposure?

To determine whether exposure to low levels of styrene (below 110 mg/m3) causes acute behavioural effects and symptoms that may be related to concentrations of styrene in air or urinary mandelic acid or both, 12 men occupationally exposed to styrene were studied and compared with a reference group of 10 unexposed men. Simple reaction time was measured before and after work and information about symptoms was obtained by questionnaire. Active and passive sampling of airborne styrene was carried out and urinary mandelic acid concentrations were measured. Although the size of the study groups is small, the results indicate that exposure to styrene below 110 mg/m3 does not cause any acute adverse effects on the central nervous system.     

An investigation into the health of kapok workers.

Kapok is a cotton-like fibre obtained from the fruits of Ceiba pentandra, a tree surgeon in tropical countries. In Sri Lanka ginning of kapok is usually done by machine in poorly ventilated buildings where workers are exposed to a great deal of dust. Forty-one workers in five ginneries in Colombo were examined. Mill fever occurred in 28 (77-8%) of the 36 workers who were able to give a history. Chronic bronchitis, which is an uncommon condition in Sri Lanka, was detected to seven workers with an average of 20-9 years' service in the industry. It is suggested that chronic bronchitis is an occupational hazard of workers who are exposed to kapok dust for long periods. Byssinosis was not found in any of the workers studied.     

An investigation into the effects of vacations on the health status in male white-collar workers

There are many stress factors in occupational settings, and the lack of vacations could be one of factors in the context of work stress. The authors have been studying the relationship between workload and employee health. This time, an investigation into the effects of leisure vacations on worker health status using male white-collar employees aged 20–60 years engaged in a manufacturing company was conducted. The subjects were questioned on work stress factors including vacations and modifiers in their occupational settings, and on psychological and physiological stress reactions; that is, how often they were able to take leisure vacations every year, their average working hours a day and work stress factors from the Demand-Control-Support model. The questions also examined other factors concerning the employees such as type-A behavior and lifestyles as modifiers, diseases of the employees, physical complaints, feelings about sleep, perceived stress, job and life satisfaction, and stress reactions as measured by physiological examination. Correlation and logistic regression analysis were conducted with the 551 eligible subjects. The results were as follows: Leisure vacation was decreasingly related to some of psychological stress reactions after adjustment was made for working hours and for modifiers. Less vacation was increasingly related to the workers’ diseases especially among the employees aged 20–34, though the association was not statistically significant. Vacations did not show obvious association with physiological measures. These findings demonstrate the effectiveness and possibility of leisure vacation in controlling fatigue and maintaining the health of workers. Vacation should always be taken into consideration as a stress factor in a survey of the health problems of white-collar workers.     

Use of complementary and alternative medicines among factory workers: investigation of workers in manufacturing]

To elucidate the situation of complementary and alternative medicines (CAM) in an occupational health setting, workers in a factory of a housing construction business were surveyed using self-administered questionnaires on their utilization of CAM in the past 12 months, out-of-pocket expenditures on CAM and ordinary western medicines (OWM), and reasons for the use of CAM. A total of 263 workers (84.3%) completed the questionnaires. Among them, 134 (51%) had received CAM therapy in the last 12 months: i.e. nutritional and tonic drinks (35.4%), supplements (16.3%), massage (13.7%), chiropractic or osteopathy (8.7%), health-related appliances (6.5%), herb or kampo (3.4%), aromatherapy (1.9%), acupuncture (1.9%), or other therapy (1.5%). Reasons for the use of CAM was "the condition was not serious enough to warrant OWM" and "expectation of health promotion or disease prevention" for 70 (51.9%) and 53 (39.3%) subjects, respectively. Average annual out-of-pocket expenditures for CAM and OWM were 17,500 and 21,300 yen, respectively. It seems important to further widen awareness and knowledge of CAM in occupational health.     

平板玻璃厂工人体力劳动强度的调查

本文对平板玻璃厂工人体力劳动强度的调查结果表明,该厂9个工种的平均劳动时间率为58%(18～83%);8小时工作日平均耗能为7010kJ/man(4043～9190)。在所调查的9个工种中,劳动强度属Ⅰ级占33.3%,Ⅱ级占44.4%,Ⅲ级占22.3%。与其它玻璃制品行业比较,平板玻璃厂主要特点是劳动耗能量大,工时利用率低。为此,建议今后应改进生产工艺与劳动条件,合理劳动定额、定员,提高工时利用率,降低体力劳动强度。     

工厂外来女工艾滋病干预前后分析

目的 了解珠江三角洲工厂外来女工艾滋病相关知识、态度、信念、行为(KABP)，评价艾滋病干预效果。方法 采用面对面匿名同卷法，对珠江三角洲某市4个制衣厂的外来女工进行基线调查，并对该人群进行艾滋病综合措施干预，干预后再进行调查。结果 工厂外来女工对艾滋病缺乏基本了解，艾滋病传播途径和预防方法的知晓率均较低，安全套使用率低，是艾滋病的脆弱人群。经干预，工厂外来女工的艾滋病传播途径和预防方法的知晓率均显著提高，安全性行为率增高，安全套使用率增高。结论 干预取得明显效果。     

Cytogenetic and hematological effects in plastics workers exposed to styrene

For 20 glass-reinforced plastics workers exposed to styrene and 22 unexposed referents, the frequency and size distribution of micronuclei were determined for lymphocytes stimulated with phytohemagglutinin or pokeweed mitogen, and white blood cell counts were made. Furthermore, chromosome aberrations were scored for 11 of the exposed subjects and 15 of the referents. The mean level of styrene in the breathing zone of the workers was 56 mg/m3. Workers exposed to styrene did not show an increase in any of the cytogenetic end points studied when the effect of age and smoking was allowed for in a multiple regression analysis. A significant 30% increase in the number of peripheral monocytes was observed for the exposed workers. No correlations between the cytogenetic and hematological tests on one hand and the length of exposure time on the other could be detected.     

Long term radiological effects of short term exposure to amosite asbestos among factory workers.

Chest radiographs were read from a sub-cohort of 386 factory workers with short term exposure to amosite asbestos (median exposure six months) and long follow up (median 25 years). Prevalence of abnormality was determined independently by two readers from the first film available after 20 years from first employment. Serial films were obtainable for 238 men (median interval from first to last film: nine years). Progression was classified with a direct progression scoring scale. Individual dust exposure estimates were derived from dust counts from two similar plants. With as little as one month or less of employment, about 20% of the films showed parenchymal abnormality and about a third showed pleural abnormality. Those in the lowest cumulative exposure stratum (less than 5 fibre-years/ml) were similarly found to have high rates of abnormality. Dose-response relations were present in the data of both readers. Smokers had higher rates of parenchymal abnormality. On multivariate analysis, cumulative exposure was the exposure variable most closely related to parenchymal abnormality, and time from first employment was the variable most closely related to pleural abnormality. Progression (including first attacks) 20 or more years after ceasing employment occurred and was more common for pleural than for parenchymal abnormality. It is concluded that with exposure to high concentrations to amosite such as existed in this factory and with follow up for at least 20 years, (1) exposure for as little as a month was sufficient to produce radiological signs of parenchymal and pleural fibrosis, (2) no cumulative exposure threshold for parenchymal and pleural fibrosis was detectable, and (3) parenchymal and pleural progression were still detectable >/= 20 years after the end of exposure.     

Long term radiological effects of short term exposure to amosite asbestos among factory workers.

Chest radiographs were read from a sub-cohort of 386 factory workers with short term exposure to amosite asbestos (median exposure six months) and long follow up (median 25 years). Prevalence of abnormality was determined independently by two readers from the first film available after 20 years from first employment. Serial films were obtainable for 238 men (median interval from first to last film: nine years). Progression was classified with a direct progression scoring scale. Individual dust exposure estimates were derived from dust counts from two similar plants. With as little as one month or less of employment, about 20% of the films showed parenchymal abnormality and about a third showed pleural abnormality. Those in the lowest cumulative exposure stratum (less than 5 fibre-years/ml) were similarly found to have high rates of abnormality. Dose-response relations were present in the data of both readers. Smokers had higher rates of parenchymal abnormality. On multivariate analysis, cumulative exposure was the exposure variable most closely related to parenchymal abnormality, and time from first employment was the variable most closely related to pleural abnormality. Progression (including first attacks) 20 or more years after ceasing employment occurred and was more common for pleural than for parenchymal abnormality. It is concluded that with exposure to high concentrations to amosite such as existed in this factory and with follow up for at least 20 years, (1) exposure for as little as a month was sufficient to produce radiological signs of parenchymal and pleural fibrosis, (2) no cumulative exposure threshold for parenchymal and pleural fibrosis was detectable, and (3) parenchymal and pleural progression were still detectable >/= 20 years after the end of exposure.     

烟草企业磷化氢暴露人员心血管及呼吸系统损伤跟踪调查

以某烟草厂接触磷化氢作业工人作为磷化氢组，选择同年体检的普通作业工人作为对照组，同时建立为期4年的动态随访。结果显示，磷化氢作业工人胸片异常率及血压值高于对照组；随着职业暴露年限增加，磷化氢作业工人血压、心电图及胸片异常率逐年增高。提示磷化氢对职业暴露工人可能存在心血管及呼吸系统毒性作用，应加强个人防护。     

Effect of highway driving on the health of factory workers

Commuting transportation is one of the important factors in the administration of safety management in industries. Most workers commute to work by car and are certain to make use of highways, mainly because of the special condition of factory locations. In this study, we investigated the effect of communicating by car on the health of factory workers. The proportion of males was significantly higher in the highway (HW) group than in the non-highway (NHW) group, and the former was younger than the latter. BMI, systolic blood pressure, diastolic blood pressure, and total cholesterol deteriorated significantly in the NHW group after 5-year periodic medical checkups. However, in the HW group, those factors did not change except for systolic blood pressure and significant improvements in triglyceride. The percentage of those who follow a good lifestyle regarding excise and nutrition, and have a solution for stress, was lower in the HW group than in the NHW group. Nevertheless, the percentage of those who did not feel stress was significantly higher in the HW group than in the NHW group, suggesting a stress-relieving effect of highway driving. Highway driving might have an unexpectedly good impact on the health of factory workers.     

工厂外来女工艾滋病干预模式研究

目的 了解珠江三角洲工厂外来女工艾滋病相关知识、态度、信念、行为(KABP)，探索适合该人群的有效的艾滋病干预模式。方法 采用匿名问卷法对外来女工进行基线调查后开展针对该人群的艾滋病综合干预措施，并对干预结果进行评价。结果 工厂外来女工艾滋病知晓程度非常低，缺乏自我保护意识和能力，生殖健康状况较差，是艾滋病的脆弱人群。干预后，其对艾滋病传播途径和预防方法的知晓率显著提高，安全性行为率增高，安全套使用率增高。结论 干预模式取得明显效果，可在该类人群中推广。     

某地毯厂织毯工手指变形调查

对某地毯厂织毯工手指变形情况调查.结果显示织毯可致作业者手指变形,主要表现为食指尺侧弯.     

Field study to explore possible effects of styrene on auditory function in exposed workers

OBJECTIVES: We conducted this study to examine, whether occupational styrene exposures are associated with reduced hearing ability. METHODS: The auditory function was investigated by pure tone audiometry and registration of transitory evoked otoacoustic emissions (TEOAE) in 32 workers of a fibre-reinforced plastic boat building factory. Sixteen subjects were laminators (mean age: 41 yr (SD: 8)) and therefore regularly exposed to styrene with mean duration of exposure to styrene of 7.5 yr (SD 5.0). The tests were applied to a reference group of 16 workers (mean age: 39 yr (SD: 8)) who were not directly exposed to styrene but had a similar noise exposure. RESULTS: A few and isolated correlations between the parameters of hearing acuity and exposure indices, such as current internal styrene exposures (sum of MA and PGA) and duration of styrene exposure, were statistically significant, but no consistent association was found. CONCLUSION: The results of this study do not support the assumption of an ototoxic effect of chronic styrene exposure in workers.