播散性多发性血管球瘤1例

患者,女,20岁。躯干散在紫蓝色结节2年。组织病理示:真皮内多个形状不规则囊腔,部分囊壁由单层细胞组成,部分由多层细胞组成。免疫组化示:SMA(+),Actin(+)。诊断为播散性多发性血管球瘤。     

播散性血管球瘤1例

患者男,29岁。四肢、臀部起蓝色结节1年余。皮损约数十个,蓝色或蓝黑色,质软可压缩,部分有触痛。组织病理示:真皮下部及皮下组织见大量纡曲扩张血管腔,管壁内衬一层血管内皮细胞,其外有一层至数层血管球细胞。免疫组化:平滑肌肌动蛋白(+),波形蛋白(+),CD31(-)。结合临床表现、组织病理改变及免疫组化染色结果诊断:播散性多发性血管球瘤。     

局限性多发性血管球瘤

患者女,24岁。 主诉：右内踝后部起暗紫红色丘疹和蓝黑色结节1年余。 现病史：患者于1年前无意中发现右内踝后上方出现二三个米粒大暗紫红色丘疹,无明显自觉症状,未就诊。此后丘疹逐渐增大、增多,鞋后帮不慎碰到丘疹时有针刺样疼痛,其疼痛与寒冷、进食刺激性食物（如辣椒、醋、蒜等）无明显关系。起病前局部无明确外伤史。患者既往体健,无皮肤及内脏肿瘤病史。家族中无类似疾病患者。为明确诊断,于2006年5月17日来我院皮肤科门诊就诊。     

腰部单发性血管球瘤一例

临床资料患者,男,58岁。左腰部淡紫红色结节伴触痛6个月。6个月前患者无意中发现左腰部出现一绿豆大淡红色皮下结节,微隆起皮肤表面,无痛痒,未介意。后结节渐增大至豌豆大,颜色渐变为淡紫红色,触痛明显,无放射痛。为明确诊断、进一步治疗来本院就诊。患者既往体健,发病前否认外伤史.     

右前臂单发性血管球瘤1例

患者男,58岁。右前臂出现单个结节伴触痛5年。皮肤科情况:右前臂伸侧一个黄豆大淡蓝红色结节,结节表面光滑,可见毛细血管扩张。皮损组织病理:真皮中下部可见瘤细胞团块,瘤团由血管腔和血管球细胞组成。免疫组化:血管球细胞vimentin(+),SMA(+),S-100(-)。诊断:单发性血管球瘤。     

播散性黄瘤1例

患者男,33岁。全身皱褶处出现多个棕红色丘疹结节。免疫组化CD68(+),S-100蛋白阴性。血脂水平正常。     

甲床外单发性血管球瘤

报告1例血管球瘤.患者男,46岁.颈部左侧豆大红色带蒂肿物10年,疼痛5年.皮损组织病理检查示表皮萎缩变薄,基底层黑素增加,真皮内可见肿瘤细胞团块,主要由大量均匀一致的血管球细胞和扩张的血管腔组成,免疫组化染色:平滑肌肌动蛋白(SMA)(+++),波形蛋(vimentin)(++),结蛋白(desmin)、S-100蛋白、CD34、CD31均(-),诊断为甲床外单发性血管球瘤.     

播散性黄瘤1例

患者男,48岁。主诉面、颈部黄色丘疹5年,伴烦渴、多饮、多尿半年,于2002年3月30日入院。患者于5年前,无明显诱因于右面颊部、右侧腋窝出现数粒针头大的红色丘疹,无自觉症状,未予以注意。后丘疹逐渐增多、增大,渐累及整个面部及左侧腋窝,不伴痒痛。曾就诊于当地医院,具体诊治情况不详。2年前,颈部、腰部、下腹部逐渐出现类似皮损,原有皮损继续增多、增大,部分融合,曾在外院行皮损组织病理检查,检查报告示“黄色瘤”,未予以治疗。半年前开始出现烦渴、多饮、多尿(尿量具体不详)、纳差、全身乏力。平素体健,无高脂饮食习惯及烟酒嗜好,两代家族…     

播散性黄瘤1例

患者男,10岁。全身起皮疹5年,伴烦渴、多饮、多尿3年。结合病史、临床表现、实验室检查及组织病理改变,确诊为播散性黄瘤。     

播散性黄瘤1例

患者男,16岁,因腘窝,股部起棕黄色丘疹8年,口渴,多饮,多尿1年,于2003年3月3日来我院就诊。患者于8年前无明显诱因于腘窝,股部起米粒大粽黄色扁平丘疹,微痒,以后皮损逐渐增大,增多,波及面部,颈部,躯干及四肢,     

Localized form of multiple glomus tumors: report of the first case showing partial involution

We recently examined a boy with relatively large multiple glomus tumors on the left scapular region. Histologic examination revealed a typical non-capsulated glomangioma in the middle and deep dermis; by electron microscopic examination, the tumor cells were seen to exhibit a characteristic smooth muscle cell structure. Thermographic examination revealed the higher temperature of the tumor. Within a year, the tumor showed a partial involution. We think this is the first report of multiple glomus tumor showing a partial involution.     

甲下血管球瘤

报告1例甲下血管球瘤。患者男,36岁。右示指甲下暗红色丘疹,并伴有放射性刺痛10年。组织病理检查示肿瘤位于真皮内,有假包膜,境界清楚,瘤内可见血管腔,周围绕以多层血管球细胞,基质中有较多肥大细胞及黏蛋白沉积。免疫组化染色结果示肿瘤细胞波形蛋白、肌动蛋白、CD34均（＋）,结蛋白、FⅧ均（-）。诊断：血管球瘤。     

A case of multiple subungual glomus tumors associated with neurofibromatosis type 1.

Glomus tumor is a distinctive neoplasm characterized by the presence of cells that resemble the modified smooth muscle cells of the normal glomus body, which is a specialized form of arteriovenous anastomosis. We report a case of multiple subungual glomus tumors associated with neurofibromatosis and review the literature on the pathophysiology of this association.     

播散性带状疱疹一例

患者,女,51岁。左下肢红斑及水疱伴阵发性疼痛20余天,泛发伴发热1周。皮肤科检查：全身散在分布粟粒至黄豆大暗紫红色斑疹、丘疹及丘疱疹,部分融合成片,中央处可见褐色痂皮。细胞涂片可见多核巨细胞及核内包涵体。诊断：播散性带状疱疹。予以甲泼尼龙、更昔洛韦等治疗有效。     

An incidental finding of an asymptomatic intraneural glomus tumor: A case report and review of the literature

Glomus tumors are rare, soft‐tissue neoplasms arising from the thermoregulatory neuromyoarterial glomus bodies. They are commonly observed in the extremities and typically present with symptoms of cold hypersensitivity, pain and localized tenderness. Intraneural glomus tumors (INGTs) are even rarer. Here we review the literature on INGT and present an unusual case of an asymptomatic INGT, found incidentally within the excision specimen of a spiradenocarcinoma that arose near the natal cleft. Interestingly, this had not been identified on magnetic resonance imaging (MRI) used to investigate the spiradenocarcinoma. Although glomus tumors are usually considered benign, malignant transformation has been reported, highlighting the need for reporting pathologists and treating clinicians to be aware of this entity.     

播散型匐行性穿通性弹性纤维病1例

报告1例播散型匐行性穿通性弹性纤维病。患者男,17岁。全身出现成片丘疹伴轻度瘙痒8个月。皮肤科检查示面颈部、躯干、四肢泛发对称的米粒大红色角化性丘疹,排列成线状、环状、半环状或匐行状。组织病理检查显示：表皮角化过度,棘层肥厚,部分表皮穿通,形成管道,真皮上部弹性纤维增多呈嗜碱性变性,其周围可见混合性炎性细胞及嗜碱性碎片组成的异物肉芽肿。     

Localized multiple glomus tumors of the face and oral mucosa

We describe a 54-year-old patient with an unusual localization of localized multiple glomus tumors. She had several nodules on the left mandibular area, lower lip, and anterior part of the buccal mucosa. A biopsy taken from the left mandibular area showed cystically dilated vessels lined by endothelial cells and a few outer layers of glomus cells in the dermis to subcutis. Localized multiple glomus tumors are rare, and both their facial and oral mucocal localization are extremely rare.     

Subungual glomus tumor diagnosis based on imaging

A 50-year-old woman had had tenderness of the nail bed of the right thumb for more than 20 years. For the previous 5 or 6 years, she had also had attacks of pain with exposure to cold, and deformity of the right thumb nail plate began to appear. There was red discoloration on the proximal aspect of the nail bed, and a longitudinal fissure on the distal aspect of the nail plate. Ultrasonography showed a well-circumscribed hypoechoic area under the proximal aspect of the nail plate and the nail matrix. Color Doppler ultrasonography showed subtle flow signals within the hypoechoic area. Magnetic resonance imaging showed a well-circumscribed mass in the same place that the ultrasonography indicated. It was isointense to the dermis of the nail bed on the T1-weighted image and hyperintense on the T2-weighted image. Radiography showed subtle dorsal bone erosion in the distal phalanx. Surgery was performed. Histologically, the diagnosis of a subungual glomus tumor was made. We diagnosed the exact location and size of the subungual glomus tumor by preoperative imaging and completely removed it easily and safely. Imaging is very useful for diagnosing tumors of the nail unit.     

血管球瘤15例临床病理分析

对15例血管球瘤患者进行回顾性分析,皮损均表现为皮下红蓝色小结节,其中甲下5例,指腹2例,上肢3例,大腿内侧2例,肩部1例,腰部1例,膝外侧1例.15例患者均出现不同程度疼痛,其中5例甲下皮损对冷刺激更敏感.15例患者皮损组织病理分为四种类型,其中经典型2例,黏液型4例,球血管瘤型8例,球血管肌瘤型1例.免疫组化示15...