中医防治脚湿气

脚湿气,又称香港脚,是一种令人烦恼的疾病。其发生是由于环境潮湿、通风不良,致使真菌大量滋生所致,以夏秋季节加重,冬春季节减轻为特点。皮损表现为水疱、糜烂、角化过度、脱屑、皲裂等,往往以其中一两种损害为主,常先发生于足部一侧,而后迁延两侧。患者主观感觉局部疼痛、灼热、瘙痒,如果糜烂严重,常因流     

大疱性类天疱疮合并神经系统疾病6例分析

正大疱性类天疱疮(Bullous pemphigoid,BP)是一种非遗传性自身免疫性皮肤病,大多发生于老年人,临床上相对少见。以水肿性红斑基础上,发生紧张性水疱和大疱为主要临床特征。Nikolsky征阴性,其组织病理为表皮下水疱,直接及间接免疫荧光可检测到抗皮肤基底膜自身抗体。一般多为单独发病或首发疾病。近些年,在既往有脑血管病、痴呆等神经系统疾病的患者中发生大疱性类天疱疮的病例并不少见,并已引起皮肤科医生的关注。     

寻常型天疱疮患者的护理

1 病历摘要患者,男,47岁。因无明显诱因反复发作性口腔溃疡4月伴全身皮损1月入院。查体:口腔粘膜内多处破溃、糜烂,无脓性分泌物。颈部、躯干、腋下、腹股沟及四肢可见散在水疱,疱液清、疱壁薄,部分破溃、糜烂,创面有较多黄色渗液。生命体征正常,白细胞计数6.7×10~9/L。入院后经皮质激素、免疫抑制剂、抗感染、能量合剂等治疗及精心护理,水疱     

中医辨治小儿炎性线样疣状表皮痣一例

报告一例小儿炎性线样疣状表皮痣。患儿,男,3岁。皮损单侧分布,表现为角化性丘疹、斑块,为炎性、角化性丘疹及斑块。出生后即发病,自觉皮损瘙痒剧烈,自幼在左大腿内侧及左上肢内侧皮肤出现红色丘疹及鳞屑性斑块,其上述部位均可见米粒大小的红色丘疹,逐渐融合成片,增厚,呈条状,片状分布,随年龄增长,皮疹向上臂及大腿内侧远端发展,形成密集的细小红斑丘疹及覆细鳞屑的红色条状斑块。组织病理改变主要为角化过度伴角化不全,棘层肥厚,真皮浅层及血管周围炎性细胞浸润。组织病理符合炎性线样疣状表皮痣。中医滋阴清热法治疗有效。     

乳头发瘁谨防两种病

很多女性都有过乳头发痒的感觉，乳头瘙痒，应该注意有无以下两种疾病。湿疹湿疹是乳头瘙痒常见病因，可发生于各个年龄段的人群。乳头湿疹好发于乳头、乳晕及其周围，针头大小的丘疹、水疱密布，边界清楚，常伴有渗液、糜烂，可出现少量鳞屑或薄痂，有时可发生皲裂，自觉瘙痒并有疼痛。     

治疗念珠菌阴道炎的新方法——口服里素劳 每日口服2片,连续5日即可治愈

念珠菌阴道炎(俗称霉菌性阴道炎)是很常见和多发的妇科感染性疾病。临床自觉症状和体征表现有:外阴、阴道瘙痒及烧灼感,充血性水肿、水疱、浓疱,糜烂或潜在溃疡,其白带呈泡沫或乳酪状,味臭,白带分泌增加,一些患者有排尿灼痛及性生活困难,同时性同伴也可受感染。发病原因多因早孕、新婚、阴部不洁,外用激素和抗生素等有关。     

治疗念珠菌阴道炎的新方法——口服里素劳

念珠菌阴道炎(俗称霉菌性阴道炎)是很常见和多发的妇科感染性疾病,临床自觉症状和体征表现有:外阴、阴道瘙痒及烧灼感,充血性水肿、水疱、脓疱,糜烂或潜在溃疡,其白带呈泡沫或乳酪状,味臭,白带分泌增加,一些患者有排尿灼痛及性生活困难,同时性同伴也可受感染。发病原因多因早孕、新婚、阴部不洁,外用激素和抗生素等有关。     

治疗念珠菌阴道炎的新方法——口服里素劳

念珠菌阴道炎(俗称霉菌性阴道炎)是很常见和多发的妇科感染性疾病。临床自觉症状和体征表现有:外阴、阴道瘙痒及烧灼感,充血性水肿、水疱、浓疱,糜烂或潜在溃疡,其白带呈泡沫或乳酪状,味臭,白带分泌增加,一些患者有排尿灼痛及性生活困难,同时性同伴也可受感染。发病原因多因早孕、新婚、阴部不洁,外用激素和抗生素等有关。     

治疗念珠菌阴道炎的新方法——口服里素劳

念珠菌阴道炎(俗称霉菌性阴道炎)是很常见和多发的妇科感染性疾病。临床自觉症状和体征表现有:外阴。阴道瘙痒及烧灼感,充血性水肿、水疱、浓疱,糜烂或潜在溃疡,其白带呈泡沫或乳酪状,味臭,白带分泌增加,一些患者有排尿灼痛及性生活困难,同时性同伴也可受感染。发病原因多因早孕、新婚、阴部不洁,外用激素和抗生紊等有关。     

治疗念珠菌阴道炎的新方法——口服里素劳((R))

念珠菌阴道炎(俗称霉菌性阴道炎)是很常见和多生的妇科感染性疾病,临床自觉症状和体征表现有:外阴、阴道瘙痒及烧灼感,充血性水肿、水疱、脓疱,糜烂或潜在溃疡,其白带呈泡沫或乳酪状,味臭,白带分泌增加,一些患者有排尿灼痛及性生活困难,同时性同伴也可受感染。发病原因多因早孕、新婚、阴部不洁,外用激素和抗生素等有关。     

Sequential study of the pathology of Prudhoe Bay crude oil in chicken embryos

Ten microliters of Prudhoe Bay crude oil was applied to the shell of fertile leghorn chicken eggs on Day 9 of incubation. Gross and microscopic pathological changes were examined in embryos surviving 1, 2, 4, and 9 days after treatment. Liver necrosis, renal lesions, and extensive edema appeared 2 days after treatment and reached maximal prevalence 4 days after treatment. There was minimal repair of the lesions from Day 4 to Day 9 after treatment. Pathological changes, including liver necrosis, mineralization in the kidney, infiltration by a large number of heterophils in the liver and spleen, subcutaneous edema with formation of large blisters, and reduction in body weight and length were still present on Day 18 of incubation, close to hatching time.     

皮肤镜毛孔检测方法在2940nm铒像素激光治疗毛孔粗大中的效果观察

目的探讨皮肤镜毛孔检测方法在2940 nm铒像素激光治疗毛孔粗大中的效果。方法选取我院2018年1月至2019年3月收治的毛孔粗大患者58例,采用飞顿辉煌激光光子工作站2940 nm铒像素激光治疗,依据面部毛孔标准照片评估治疗前后的毛孔粗大和皮肤情况,并经毛孔检测系统评估患者治疗前后的面积量化值和色差量化值,统计患者的不良反应发生率。结果治疗后,降低3等级2例,降低2等级24例,降低1等级30例,无变化2例;患者治疗前后的评级差异有统计学意义(P<0.05)。患者治疗后的面积量化值和色差量化值均低于治疗前(P<0.05)。58例患者治疗后均出现短暂红斑水肿,时间<48 h,有轻微结痂,无色素沉淀或减退,未出现水疱、红斑等不良反应。结论皮肤镜毛孔检测方法在2940 nm铒像素激光治疗面部毛孔粗大中的临床效果明显,毛孔面积量化值、色差量化值均降低,不良反应较少,具有较高的临床应用价值。     

Pustular and vesicular skin eruptions in newborns

Four neonates with vesicopustular skin eruptions, 1 girl and 3 boys, were diagnosed with feeding blisters, bullous impetigo, erythema toxicum neonatorum and transient neonatal pustular melanosis, respectively. The neonate with bullous impetigo was treated with antibiotics; the remaining neonates were not treated. The neonate with transient neonatal pustular melanosis developed hyperpigmentation, whereas the other neonates recovered without sequelae. Skin lesions in neonates are common and frequently cause parental concern. Most causes of neonatal pustular and vesicular skin eruptions are benign and transient. However, some skin lesions must be recognised and treated rapidly. Therefore it is important to identify these neonatal skin eruptions based on a thorough history of the mother and child and clinical presentation. Skin culture may be helpful in some cases.     

蒲地蓝消炎口服液联合碘伏治疗假丝酵母菌性包皮龟头炎临床观察

目的:观察蒲地蓝消炎口服液联合碘伏外用,治疗假丝酵母菌性包皮龟头炎的疗效。方法:将120例假丝酵母菌性包皮龟头炎患者随机分为研究组及对照组,研究组(蒲地蓝消炎口服液口服联合碘伏外用)60例,对照组(2%咪康唑乳膏外用)60例。详细记录2组患者的瘙痒、红斑、丘疹、浸渍、糜烂、水疱的消退时间并进行比较。结果:治疗随访10 d时,研究组总有效率为96.67%,对照组为86.67%,2组比较差异有统计学意义(P0.05)。研究组瘙痒、红斑、丘疹、浸渍、糜烂、水疱的消退时间分别为(1.35±0.16)d、(1.43±0.38)d、(5.72±0.66)d、(2.43±0.39)d、(4.62±0.65)d和(3.32±0.36)d,对照组则分别为(2.32±0.56)d、(2.63±0.60)d、(8.31±1.32)d、(3.93±0.81)d、(7.63±1.27)d和(4.62±0.55)d,2组比较差异有统计学意义(t值分别为12.900 9,13.087 9,13.5940,12.924 3,16.342 5和15.318 9,均P0.001)。结论:蒲地蓝消炎口服液口服联合碘伏外用治疗假丝酵母菌性包皮龟头炎,可明显控制局部炎症反应,瘙痒、红斑、丘疹的消退时间快,可有效缩短病程,值得临床推广。     

Erythema multiforme--oral manifestations

Modern scientific achievements in the etiology, pathogenesis, diagnosis and treatment of the vesiculobullous lesions of the oral mucosa are of basic significance for the students, who study the diagnosis and the treatment of these diseases, as well as for the clinical practitioners in their everyday practice. The presented new information about the drug-induced or herpes-associated erythema multiforme, the more severe forms - the Stevens-Johnson syndrome and the toxic epidermal necrolysis, is necessary for each practising dentist especially in the diagnosis and treatment of medically compromised patients. Modern investigations confirm the susceptibility of these patients to infections due to primary or secondary immune deficiency. The clinical oral manifestations of erythema multiforme and their treatment are presented.     

Standardized multicolored magnetic resonance images of gynecologic lesions

PURPOSE: The purpose of this study was to develop a convenient and simple method for visualizing in color the features of gynecologic lesions by combining T1- and T2-weighted magnetic resonance images using RGB (red-green-blue) color channels. MATERIALS AND METHODS: T1- and T2-weighted film images of gynecologic lesions were digitized using a film-scanner. The signal intensities of fat on T1-weighted images were converted to 133% of those on T2-weighted images. Additive multicolored images in the RGB color system were produced from T1- and T2-weighted images using color axes of a complementary color pair for a total of 84 typical gynecological lesions. RESULTS: Tissues were displayed in color as follows: fat: light tan; urine: light blue: muscle: dark brown; endometrium: light blue; leiomyomas with cystic degeneration: cyanblue; cellular leiomyoma: yellowish brown; endometrial cyst: orange. The images of female intrapelvic structures and gynecologic lesions were semi-natural in appearance. CONCLUSION: Standardization of fat intensities provides a simple method for multicolored visualization of the features of gynecologic lesions.     

Morphologic and clinical aspects of chronic gastric erosions

Chronic erosions of the stomach are mostly papular lesions of the gastric mucosa with large base, 0.5-1 cm in diameter, often with superficial central depression covered with fibrin, less frequently without it. The typical site of lesion is the antrum the chronic erosions are here manifold, solitary forms are infrequent. In the course of 5694 gastroduodenoscopies the authors observed in 198 patients (5.2%) typical endoscopic picture of chronic erosions. In biopsy samples volcano-type lesions of the mucous membrane characteristic of the disease were found. According to the results the chronic erosions of the stomach are lesions of aspecific symptomatology, the disturbance of the mucosal barrier cannot be made probable. It is important to know the morphological characteristics of the rather frequent independent entity also for separating it from adenomas. Malignant transformation was not found in the material of the authors.     

Management of toxic epidermal necrolysis

Toxic epidermal necrolysis and Stevens-Johnson syndrome are rare, life-threatening drug reactions. Widespread epidermal necrosis and mucosal erosions lead to complications similar to those developing after extensive burns. Treatment is supportive. The role of steroids and other potential disease-modifying agents remains to be established by controlled studies.     

Stomatitis in childhood, not always benign

Two boys of 1 and 16 year had painful buccal lesions and were admitted for dehydration. The younger had finger and toe blisters; the older, severely ill, had conjunctivitis, urethritis and skin lesions. Only symptomatic treatment with lidocaine gel and paracetamol gave good recovery. A 5-year-old Turkish girl had recurrent painful buccal ulcers which each time cleared up spontaneously. Stomatitis is common in childhood. Viral infections are the most common causes of stomatitis, in particular infections with herpes simplex virus (herpes gingivostomatitis), Coxsackie virus (herpangina, hand-foot-mouth-disease), chickenpox and infectious mononucleosis. Bacterial infections are rare and mostly secondary to the viral infections. In infants oral candidiasis (thrush) is a common cause of stomatitis. Most infections are self-limiting and reassurance of parents is important. Dehydration is a common complication and admission to hospital can be prevented by analgesics. The most important non-infectious conditions that cause stomatitis in children are recurrent aphthous stomatitis, erythema multiforme major (Stevens-Johnson syndrome), Beh?et's disease, malignancy (leukaemia), immune-mediated disorders (agranulocytosis, cyclic neutropenia), traumata, blistering disorders of the skin and lichen planus. A complete history and a thorough physical examination usually give the correct diagnosis and further investigations are seldom necessary.     

Oral Pemphigus Vulgaris: Case Report

Background

Pemphigus is a potentially life threatening autoimmune disease that causes blisters and erosions of the skin and the mucous membrane. The epithelial lesions are a result of auto-antibodies that react with desmosomal glycoproteins that are present on the cell surface of the keratinocyte. The autoimmune reaction against these glycoproteins causes a loss of cell to cell adhesion, resulting in the formation of intraepithelial bullae. Eighty to ninety percent of patients with pemphigus vulgaris develop oral lesions and in 60% of cases oral lesions are the first sign. Timely recognition and therapy of oral lesion is critical as it may prevent skin involvement. If treatment is instituted during this time, the disease is easier to control and the chance for an early remission of the disorder is enhanced.

Case Details

This case report describes the case of a patient who complained of ulcers of the mouth and difficulty in swallowing since 20 days, who was diagnosed as having Pemphigus vulgaris. Due to early diagnosis, lower doses of medication for a shorter period of time could control the disease.

Conclusion

Dental professionals must be sufficiently familiar with the clinical manifestations of pemphigus vulgaris to ensure early diagnosis and treatment which in turn determines the prognosis and course of the disease.