发展性照顾护理模式对改善早产儿喂养的效果观察

目的研究探讨发展性护理模式对改善早产儿喂养的临床效果。方法按照随机抽取方法选取我院2014年2月至2015年2月收治的早产儿78例为研究对象。在统计学原理的指导下将所有早产儿分为例数均为39例的对照组和观察组。对照组早产儿接受常规的护理,观察组早产儿实行发展性照顾护理模式,比较两组早产儿喂养效果。结果结果表明,观察组早产儿睡眠时间、住院天数、每日体质量增长以及每日奶量摄入量均明显优于对照组早产儿,数据符合统计学差异(P0.05)。结论针对胎龄不足37周的早产儿,展开发展性照顾护理模式可有效延长早产儿的睡眠时间,促使喂养更为顺利,明显提高体质量增长,缩短住院时间,提高早产儿的生活质量。     

发展性照顾护理模式在重症监护室早产儿护理中的应用

目的:探析重症监护室早产儿应用发展性照顾护理模式的临床研究。方法:选择ICU早产儿70例为观察组,应用发展性照顾护理模式,另选择同期新生早产儿70例为对照组,进行常规护理。比较两组护理后的每天进奶量、每天睡眠时间、住院时间、体重恢复正常所需时间情况。结果:护理后观察组的每天进奶量、每天睡眠时间、住院时间、体重恢复正常所需时间等情况显著优于对照组(P<0.05)。结论:重症监护室早产儿应用发展性照顾护理模式可显著提高早产儿的体重,提升早产儿的生存质量,促进早产儿正常发育,临床效果确切,值得临床推广。     

新生儿重症监护室极低体重新生儿应用发展性照顾的临床分析

目的：分析新生儿重症监护室极低体重新生儿应用发展性照顾的临床效果。方法：随机选择于2013年3月至2015年10月间入住该院的早产新生儿140例,通过随机分组的方式将其分为研究组与常规组,其中研究组给予发展性照顾,常规组给予日常护理方法。观察两组的恢复情况、住院天数、睡眠时间、留置针留置时间以及胃管留置时间。结果：研究组给予发展性照顾之后,发现患儿住院天数以及康复时间缩短,胃管留置时间、睡眠时间以及留置针留置时间均显著高于常规组（P＜0．05）。结论：对极低体重新生儿实施发展性照顾,能有效促进护理质量提升,促进患儿健康生长发育。     

发展性照顾在NICU早产儿护理中的应用效果观察

目的 探讨发展性照顾对早产儿生长发育的影响.方法将我科NICU 100例早产儿按住院时间顺序,随机分为观察组50例和对照组50例.观察组在住院后提供常规护理方法和发展性照顾护理,对照组早产儿采用常规护理方法.结果观察组早产儿每日进奶量、平均体重增长速度以及住院天数显著优于对照组,胃肠耐受性也比对照组好,2组比较差异有统计学意义(P<0.05).结论发展性照顾有利于早产儿的生长发育,从而提高了早产儿的生存质量.     

发展性照顾在新生儿重症监护室早产儿护理中的应用效果

目的:探讨在新生儿重症监护室(NICU)早产儿护理中采用发展性照顾的应用效果。方法:选取收治的88例NICU早产儿为研究对象,按照随机数字表法将其分为对照组和观察组,每组44例。对照组予常规护理,观察组在常规护理基础上予发展性照顾。对比两组胎便完全排泄时间、达到全肠道喂养时间、体质量增至正常时间、NICU住院时间、并发症发生率及患儿家属护理满意度。结果:观察组胎便完全排泄时间、达到全肠道喂养时间、体质量增至正常时间、NICU住院时间均短于对照组,且并发症发生率低于对照组,差异均有统计学意义(P<0.05)。观察组患儿家属护理工作满意度为95.46%,高于对照组的75.00%,差异亦有统计学意义(P<0.05)。结论:发展性照顾用于NICU早产儿,可减少并发症,缩短康复进程,提升患儿家属护理工作满意度。     

发展性照顾对早产儿生存质量的影响

目的:探讨发展性照顾的主要方法及对早产儿生存质量的影响.方法:选择早产儿422例,随机分为实验组和对照组各211例.对照组给予常规护理,实验组在对照组的基础上采取发展性照顾,比较2组恢复出生体重时间、每日睡眠时间、住院时间、达足量喂养量时间.结果:实验组恢复出生体重时间、达足量喂养量时间较对照组短,差异有统计学意义(P<0.01);实验组每日睡眠时间较对照组长,差异有统计学意义(P<0.01);实验组住院时间较对照组短,差异有统计学意义(P<0.01).结论:发展性照顾方法简单,且安全性高,可靠性和实用性强;能促进早产儿病情的康复.     

发展性照顾在早产儿中的临床护理应用分析

目的研究分析发展性照顾在早产儿中的临床护理应用。方法选取在我院出生的早产儿78例为本次研究对象,按照护理方式的不同分为两组,两组患儿均匀分配,观察组39例患儿接受发展性照顾护理,对照组39例患儿接受常规护理干预,对比两组患儿的临床指标变化以及早产儿的生长发育情况。结果观察组患儿护理干预后的睡眠质量、摄入奶量,住院时间和喂养耐受时间均比对照组的数值优,观察组患儿在不同时间段的体质量明显高于对照组,组间对比差异显著,P0.05。结论针对临床中的早产儿实施发展性照顾护理措施能提高早产儿的睡眠质量,增加患儿摄奶量,保证患儿快速成长发育,值得临床应用借鉴。     

发展性照顾护理模式在重症监护室早产儿护理中的应用

目的 :研究发展性照顾护理模式在重症监护室早产儿护理中的应用。方法:选取2014年1月至2016年5月我院重症监护室收治的360例早产儿随机分为两组并分析讨论,对照组进行常规护理,观察组进行发展性照顾。对两组患者的治疗情况进行比较。结果:与对照组相比,观察组新生儿的每天进奶量、每天睡眠时间等具有明显优势,住院时间、体重恢复正常所需时间明显缩短,经比较具有显著差异(P0.05),有临床统计学意义。结论:通过实施重症监护室早产儿应用发展性照顾护理模式可显著增加早产儿的体重,提升早产儿的生存质量,促进早产儿正常发育,临床效果确切,值得临床推广。     

早产儿喂养应用护理干预的效果观察

目的：探讨早产儿喂养应用护理干预对其喂养不耐受发生率、促进早产儿生长发育的效果观察。方法：随机平均将我院在2014年5月至2016年5月期间收治的60例早产儿按2014年5月至2015年4月30例早产儿为对照组,2015年5月至2016年5月30例早产儿为观察组,对照组患儿给予常规护理,观察组的则用按摩腹部、抚触以及非营养性吸允等方式进行干预。比较两组体重增长量、住院时间、腹胀发生率、胃潴留发生率、胃管留置时间。结果：观察组患儿体重增长量明显优于对照组（P＜0.05）;腹胀发生率、胃潴留发生率均低于对照组（P＜0.05）;住院时间与胃管留置时间显著短于对照组（P＜0.05）。结论：早产儿喂养应用护理干预对促进早产儿胃肠激素的分泌,加速胃肠动力成熟,降低其喂养不耐受发生率,加快早产儿生长发育,缩减住院时间有重要意义,值得临床推广。     

发展性照顾对早产儿生长发育的影响

目的:探讨发展性照顾对早产儿的影响.方法:对新生儿重症监护室收治的68例早产儿随机分为观察组35例和对照组33例,观察组在常规治疗及护理的基础上实施发展性照顾,包括鸟巢护理、暗室护理、最少干预护理、非营养性吸吮、抚触.对两组早产儿体重、奶量、喂养耐受情况进行观察.结果:两组早产儿在体重、喂养不耐受方面比较差异均有显著意义(P＜0.05).进奶量比较差异有极显著意义(P＜0.01).结论:新生儿重症监护室实施发展性照顾可促进早产儿生长发育,促进疾病恢复,提升护理质量.     

Value of D-Dimers in patients with acute aortic dissection

Objective: To evaluatel the value of D-dimers in patients with acute aortic dissection (AAD). Methods: This study consisted of 16 patients with AAD and 27 non-AAD patients. Serum D-dimets were measured by Sta-Liatest D-DI immunoturbidimetric assay. Results: D-dimer level was higher (P ＜ 0.001) in patients with AAD(7.91 ± 5.52 μg/ml) than that in non- AAD group(1.57±1.24 μg/ml). D-dimer was positive (＞0.4 μg/ml) in all patients with AAD and in 10 control group patients (37%). Among patients with acute AAD, D-dimers tended to be higher in Stanford A than in Stanford B (8.67 ± 4.31 μg/ml vs. 3.24±1.27 μg/ml, P ＜0.01). D-dimer values tended to be higher in more extended disease(3.84 ± 1.65 μg/ml, 8.57 ± 3.58 μg/ml and 11.87 ± 5.69 μg/ml in thoracic aorta, thoracic and abdominal aorta, thoracic and abdominal aorta and iliacal arteries, respectively, P ＜ 0.05 for both 8.57 ± 3.58 and 11.87 ± 5.69 vs. 3.84 ± 1.65 ). Including the control group into the analysis, we found a sensitivity of 100%, a negative predictive value of 100%, and a specificity of 66% and a positive predictive value of 64% for D-dimer in diagnosis of AAD in our patients with suspected AAD. Conclusion: D-dimer was elevated in patients with AAD. A negative D-dimer test result could be useful in excluding AAD.     

Research of combined liver-kidney transplantation model in rats

Objective： To set up a simple and reliable rat model of combined liver-kidney transplantation. Methods： SD rats served as both donors and recipients. 4℃ sodium lactate Ringer＇s was infused from portal veins to donated livers,and from abdominal aorta to donated kidneys, respectively. Anastomosis of the portal vein and the inferior vena cava （IVC） inferior to the right kidney between the graft and the recipient was performed by a double cuff method, then the superior hepatic vena cava with suture. A patch of donated renal artery was anastomosed to the recipient abdominal aorta. The urethra and bile duct were reconstructed with a simple inside bracket. Results： Among 65 cases of combined liver-kidney transplantation, the success rate in the late 40 cases was 77.5%. The function of the grafted liver and kidney remained normal. Conclusion： This rat model of combined liver-kidney transplantation can be established in common laboratory conditions with high success rate and meet the needs of renal transplantation experiment.     

BLOOD PRESSURE CHANGE WITH AGE IN SALT-SENSITIVE TEENAGERS

Objective To observe blood pressure change with age in salt-sensitive teenagers whose salt sensitivity were determined by repeated testing.Methods Salt sensitivity was determined through intravenous infusion of normal saline combined with volume-depletion by oral diuretic furosemide in 55 teenagers. After five years, salt sensitivity was re-examined and subject blood pressure was followed up. Blood pressure changes in salt-sensitive teenagers were compared to that of non-salt sensitive teenagers over five years.Results After 5 years, the repetition rate of salt sensitivity determined by intravenous saline loading is 92.7%. In teenagers with salt sensitivity on the baseline, both the systolic blood pressure increments and increment rates were much higher than non-salt sensitive teenagers (12.7±12.1 mmHg vs. 2.8±5.2 mmHg, P＜ 0.01; 12.2%± 12.0% vs. 2.5% ±4.4%, P＜ 0.001,respectively). There was a similar trend for diastolic blood pressure (8.4 ± 6.4 mmHg vs. 3.7 ± 6.4 mmHg, P = 0.052; 13.2% ±10.6 % vs. 6.8%± 10.1%, P = 0.053, respectively).Conclusions Salt sensitivity determined by intravenous saline loading showed good reproducibility. Blood pressure increments with age were much higher in salt-sensitive teenagers than non-salt sensitive teenagers, especially in terms of systolic blood pressure.     

安心颗粒对急诊经皮冠状动脉介入术后生活质量影响的研究

目的：评价使用安心颗粒对急诊经皮冠状动脉介入术（PPCI）术后生活质量的影响.方法：将160例接受PPCI的急性ST段抬高型心肌梗死患者随机分为安心颗粒组（术前顿服安心颗粒8.8g,术后安心颗粒4.4 g/次,每日2次）和对照组（仅接受基础药物治疗）.所有患者均服用阿司匹林、氯吡格雷和阿托伐他汀.分别在入院时、出院前1d、出院后180 d时,应用心肌梗死多维度量表（MIDAS）、中文版SF-36评价量表对患者生活质量评分.并观察术后30 d以内的出血并发症、血小板减少症发生情况.结果：入院时和出院前1d,两组患者的心肌梗死MIDAS、SF-36量表评分比较无差异（P＞0.05）;出院后180 d时,与对照组比较,安心颗粒组MIDAS、SF-36评分明显减低（P＜0.05）;组内与入院时比较,两组出院前1d、出院后180 d时,MIDAS、SF-36评分均降低（P＜0.05）.两组患者在随访期间均无大量出血、少量出血、重度和极重度血小板减少症发生,安心颗粒组有4例、对照组有7例发生不明显出血（P＞0.05）.两组发生轻度血小板减少症的患者数比较无差异（P＞0.05）.结论：PPCI使用安心颗粒,能改善急性ST段抬高型心肌梗死患者的生活质量,且不增加出血风险.     

The comparative studies of the influences of Urapidil and Nicardipine on sino-atrial node function, atrio-ventricular node function and hemodynamics

Objective:To investigate the influences of urapidil and nicardipine on rabbit sinus function,atrio-ventricular node function and hemodynamics.Methods:Thirty-two Angora's rabbits were selected and randomly divided into four groups.U1 group:urapidil 0.25 mg/kg;U2 group:urapidil 0.5 mg/kg;N1 group:nicardipine 10 μg/kg;N2 group:nicardipine 20 μg/kg.All these medicine were administrated within 30 seconds.Measurements were taken before and after the administration of urapidil or nicardipine for the following data:mean blood pressure(MAP),heart rate(HR),sino-atrial conduction time(SACT),maximal sinoatrial recovery time(SNRTmax)corrected sinus node recovery time(CSNRT),index of sinus node recovery time(SNRTI),Wenckebach A-V conduction frequency (WB),and P-R interval.Results:Significant MAP and HR changes were identified in all of the four groups before and after administration of both urapidil and nicardipine.No significant changes could be found in the rest of the parameters.Intergroup analysis showed that SACT and CSNRT of N1 and N2 groups were shorter than those of the U2 group(P＜0.01);the MAP decreased(P＜0.01)and the HR increased drastically(P＜0.01).Conclusions:Neither urapidil(0.25 mg/kg,0.5 mg/kg)nor nicardipine(10μg/kg,20μg/kg)has any significant influence on rabbit sinus function or rabbit atrio-ventricular node function.Nicardipine could be a better choice than urapidil for parafunctional sinus node patients.     

Expression of OPGmRNA and ODFmRNA in the patients of hip fracture due to osteoporosis

Objective：To investigate the gene expression of osteoprotegerin（OPG） and osteoclast differentiation factor（ODF） in the bone tissue of patients with hip fracture due to osteoporosis. Methods：OPGmRNA and ODFmRNA in the bone tissue in 50 cases of osteoporosis sufferers（over 50 years old） with hip fracture（Observer Group） and 30 cases of hip facture sufferers with no osteoporosis（Control group） were analyzed with the Semi-Quantitative RT-PCR method. Results：The mRNA expressed of ODF, OPG were both high in the patients with hip fracture. In the control group, the expression of OPG mRNA was observed, while the expression of ODF mRNA was very slight. Conclusion：Aged patients contained all signals including OPG, ODF that are essential for inducing osteoclastogenesis and promoting bone resorption.     

The clinicopathological and immuohistochemical analysis of solid-pseudopapillary tumor of the pancreas： report of 9 cases

Objective：To investigate the clinical features, pathological characteristics and immunophenotype of solid-pseudopapillary tumor of the pancreas（SPTP）. Methods：Nine surgically treated cases of SPTP were retrospectively reviewed. Hematoxylin and Eosin（HE） staining and immunohistochemical staining were used to analyze all cases, and the general clinical data was collected. Results：Six patients were asymptomatic except for a palpable mass. Two patients complained of vague-epigastric pain. One patient appeared jaundice. The tumor was encapsulated and solid tissues alternately with cystic tissues. Histologically, the histological structure of solid portion was pseudopapillary with a fibrovascular core. Tumor cells were uniform and medium-sized which were arranged in sheets ets or nests or pseudopapillary patterns. Immunohistochemical studies demonstrated that SPTP proved positive in vimentin（9/9 cases）, AAT（9/9 cases）, NSE（9/9 cases）, ACT（7/9 cases）, CK20（2/9 cases）, CgA（1/9 cases）, S-100（3/gcases）, PR（4/gcases）, Syn（3/9 cases） and CD56（5/9cases）, negative in CEA and ER. Conclusion：SPTP is a tumor predominantly occurring in young women frequently without special symptoms. This tumor has various characteristical histological patterns with different immunophenotype.     

Dynamic Changes in Serum Estradiol and Progesterone levels in Patients of Premenstrual Syndrome with Adverse Flow of Liver-qi

Objective:To probe into the influence of changes of ovarian hormones on the pathogenesis of the specific sub-type premenstrual syndrome(PMS)and reveal partial microcosmic mechanisms of adverse flow of liver-qi.Methods:Estradiol(E2)and progesterone(P)levels in serum were determined at different phases of menstrual cycle by radioimmunoassay.Results:In the group of PMS with adverse flow of liver-qi.the secretive peak value Of E2 and P at the follicular phase significantly decreased,and the secretive peak value at the luteal phase did not come into being.Conclusions:Low E2 and P secretive peak at the follicular phase and absence of secretive peak at the luteal phase is one of the microcosmic mechanisms of PMS with adverse flow of liver-qi.One of the pathophysiologic mechanisms of specific sub-type PMS is probably the continuous low level of E2and P.     

Real-time Three-dimensional Echocardiography in Assessment of Left Ventricular and Right Ventricular Volumes

Real-time three-dimensional echocardiography (RT3DE)is a new ultrasound technique that enables dynamic threedimensional visualization and quantification of the heart in real time. Investigation of feasibility and methodology of RT3DE in determining left ventricular (LV) and right ventricular (RV) volumes, RT3DE was performed in 35 normal adults using Philips SONOS 7500 system with a 2-4 MHz matrix array transducer. The 60°×60° "pyramid" volume database was obtained and analyzed on a TomTec echo workstation. Both LV and RV volumes were calculated with four 3DE methods (i.e. apical 2, 4, 8, and 16-plane) through manually tracing ventricular endocardial borders in end diastole and end systole. Stroke volumes were then calculated. LV volume was also measured by 2DE Simpson's rule using GE VIVID 7 ultrasound machine.     

SCREENING FOR A 21-CHROMOSOME ABNORMALITY IN PREIMPLANTED EMBRYOS OF ELDERLY WOMEN

Increasing maternal age is the only etiological factor unequivocally linked to Down's syndrome in humans. The occurrence rate of newborns with Down's syndrome is about 1/220 in women over 35 years old. However, the occurrence rate in embryos fertilized in vitro, of the elder woman is unclear. Using FISH we screened the number of chromosome 21 in preimplanted embryos of 5 elderly women (average age, 38.4 years) to study the feasibility and necessity of screening trisomy 21 in embryos in patients over 35 years old at the in vitro fertilization (IVF) center.